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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone Treatment Centers in Oklahoma

Medically reviewed by NWVCIL Editorial TeamLast reviewed: May 2026

Our directory lists 76 naltrexone providers across Oklahoma, with the largest concentrations in Oklahoma City (7), Tulsa (4) and McAlester (3).

Naltrexone (Vivitrol, Revia) is an opioid antagonist used to treat both alcohol use disorder and opioid dependence. Available as a daily oral tablet or monthly extended-release injection, it blocks opioid receptors to reduce cravings and prevent relapse.

Treatment landscape in Oklahoma:

  • Oklahoma recorded 1,278 drug overdose deaths in 2023 at 32.4 per 100,000 (CDC NCHS).
  • 82 buprenorphine providers and 16 methadone Opioid Treatment Programs serve the state; Oklahoma City and Tulsa anchor access.
  • SoonerCare covers buprenorphine and naltrexone; methadone treatment is covered at licensed OTPs concentrated in Oklahoma City and Tulsa.
  • ODMHSAS funds the Oklahoma Opioid Helpline and licenses all OTPs for state oversight.

Naltrexone in Oklahoma — By the Numbers

32.4

per 100,000 drug overdose mortality (CDC 2023)

1,278

total overdose deaths in Oklahoma (2023)

52

naltrexone providers in our directory

114 / 139

facilities offering telehealth

122

accept Medicaid for treatment

16

SAMHSA-certified Opioid Treatment Programs

Top cities by buprenorphine provider density

Oklahoma City (10) · Tulsa (7) · McAlester (3)

Sources: CDC NCHS Drug Overdose Mortality (2023) · SAMHSA Treatment Locator · NWVCIL directory snapshot, May 2026

Coverage & Regulations in OklahomaSources verified: 2026-05-14

SoonerCare

SoonerCare covers buprenorphine and naltrexone; methadone treatment is covered at licensed OTPs, primarily in Oklahoma City and Tulsa.

State regulations

Oklahoma Department of Mental Health and Substance Abuse Services (ODMHSAS) licenses OTPs and funds the Oklahoma Opioid Helpline.

SAMHSA National Helpline: 1-800-662-4357Crisis: 988Oklahoma: 1-800-522-9054 (Oklahoma Reachout)
Commonly Accepted Insurance in Oklahoma
  • Cash or self-payment46
  • Medicaid46
  • Federal, or any government funding for substance use treatment programs42
  • Private health insurance37
  • Medicare36
  • Federal military insurance (e.g., TRICARE)34
Available Treatment Settings in Oklahoma
  • Outpatient48
  • Regular outpatient treatment48
  • Outpatient methadone/buprenorphine or naltrexone treatment38
  • Intensive outpatient treatment19
  • Residential/24-hour residential8

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Naltrexone Treatment Providers in Oklahoma

Naltrexone providers in Oklahoma

Filters:

Oklahoma City · 7 centers

HOPE Community Services Inc - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Japanese+3 more
North Oklahoma County MH Center Inc - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more
Veterans Affairs Medical Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home+1 more
Spanish

Tulsa · 4 centers

Tulsa VA Outpatient Clinic - Facility Image
Insurance Accepted$$

Services:

Substance use treatment
Counseling and Recovery Services of OK - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

McAlester · 3 centers

Oklahoma Treatment Services LLC - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Stigler Health and Wellness Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home
Sign language services for the deaf and hard of hearing
Placeholder image

Carl Albert

McAlester, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Lawton · 2 centers

Catalyst - Facility Image

Catalyst

Lawton, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Muskogee · 2 centers

Eastern Oklahoma VA Healthcare System - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment
Green Country Behavioral Hlth Servs - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Stigler · 2 centers

Stigler Health and Wellness Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more
Placeholder image

Carl Albert

Stigler, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Tahlequah · 2 centers

Northeastern Health System - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Alva · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Anadarko · 1 center

Placeholder image

Kiowa Alcohol Drug

Anadarko, OK

$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Ardmore · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Chickasha · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Cleveland · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Colcord · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Cushing · 1 center

Valley Hope - Facility Image

Valley Hope

Cushing, OK

Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Edmond · 1 center

Arcadia Trails Integris Center for - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment
Sign language services for the deaf and hard of hearing

El Reno · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Elk City · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Enid · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Eufaula · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatment

Fairview · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Fort Supply · 1 center

Placeholder image
Insurance Accepted$$

Services:

Detoxification
Sign language services for the deaf and hard of hearing

Guymon · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Hobart · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Holdenville · 1 center

Placeholder image

Carl Albert

Holdenville, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Idabel · 1 center

Placeholder image

Carl Albert

Idabel, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Kingfisher · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Konawa · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Norman · 1 center

Virtue Center - Facility Image

Virtue Center

Norman, OK

Insurance Accepted$$

Services:

Substance use treatment
Sign language services for the deaf and hard of hearing

Ponca City · 1 center

Oklahoma Treatment Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatment

Poteau · 1 center

Stigler Health and Wellness Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatment
Sign language services for the deaf and hard of hearing

Sallisaw · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Stillwater · 1 center

Placeholder image

Payne County

Stillwater, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Stilwell · 1 center

CREOKS Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Watonga · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Weatherford · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Wilburton · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Woodward · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Showing 52 of 76 naltrexone providers in Oklahoma. Browse all centers in Oklahoma

Frequently Asked Questions About Naltrexone in Oklahoma

Do I have to stop using opioids before starting naltrexone?

For methadone and buprenorphine, continued opioid use during induction is common and expected; the medication itself helps stop use. For naltrexone, however, you must complete a 7–14 day opioid-free period first. Your Oklahoma clinician will tailor the induction based on your medication.

Is the first visit to a naltrexone provider free?

Some Oklahoma programs offer a free screening or phone intake; others charge an initial assessment fee ($100–$300 self-pay). Federally qualified health centers often waive the first visit. Ask up front about assessment fees when you schedule your appointment.

Does SoonerCare cover SAMHSA-required counseling along with naltrexone?

Yes. SoonerCare covers the mandated counseling component for MAT — individual therapy, group sessions, and care coordination — at participating Oklahoma clinics. Reimbursement for peer-support specialists is also available under the state plan.

Will UnitedHealthcare or Aetna cover naltrexone?

Yes. Both UnitedHealthcare and Aetna cover the MAT benefit in Oklahoma, including naltrexone. Verify in-network providers and whether long-acting injectables require prior authorization; patient-advocate lines can confirm network status before you schedule.

Are there license caps or certificate-of-need rules for new naltrexone providers in Oklahoma?

Oklahoma applies state-specific licensure review for new OTPs; some states also require a certificate-of-need demonstrating unmet demand. Existing buprenorphine prescribers do not face these caps — only methadone OTPs are subject to location-specific licensure review.

Is it harder to quit methadone than buprenorphine?

Methadone tapering generally takes longer than buprenorphine because of its long half-life and higher cumulative-dose equilibrium. Most Oklahoma clinicians taper methadone over 6–12 months or longer. Buprenorphine tapers often complete in 3–6 months for stable patients.

How do I start naltrexone treatment in Oklahoma?

Call a naltrexone clinic directly, SAMHSA’s national helpline (1-800-662-4357), or 988 for urgent help. Most Oklahoma naltrexone providers offer same-day or next-business-day intake; the intake visit includes an assessment and your first dose or prescription.

Will I feel high or sedated after the first naltrexone dose?

Most patients feel calm relief of withdrawal rather than euphoria. Mild drowsiness is common the first day; avoid driving or operating machinery until you know how you react. Severe sedation is rare and warrants a call to the Oklahoma clinic.

Is constipation on naltrexone a serious problem?

Constipation is one of the most common and persistent naltrexone side effects. Daily fluids, fiber, stool softeners, and an over-the-counter laxative like polyethylene glycol are first-line. If severe, your Oklahoma clinician may prescribe a peripherally acting opioid-receptor antagonist.

Can I deliver at any Oklahoma hospital if I’m on naltrexone?

Yes. All Oklahoma birthing hospitals are equipped to care for MAT patients. Choosing a hospital with a dedicated perinatal-addiction protocol — often larger urban hospitals — can improve experience. Discuss delivery location with your OB and MAT team well before the due date.

Will my counseling sessions be confidential?

Yes — counseling records are protected by 42 CFR Part 2 and HIPAA. The counselor cannot disclose your MAT status or session content to family, employer, or law enforcement without your specific written consent or a narrowly tailored court order.

Can I keep my naltrexone treatment private from my health-insurance company?

If you use insurance, the insurer sees billed services (including MAT). They cannot share that with your employer or family. If you strongly value privacy from insurance, self-pay is the only fully insulated option.

Other Treatment Options in Oklahoma

Naltrexone Treatment in Other States

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)