Naltrexone Treatment Centers in Oklahoma
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 76 naltrexone providers across Oklahoma, with the largest concentrations in Oklahoma City (7), Tulsa (4) and McAlester (3).
Naltrexone (Vivitrol, Revia) is an opioid antagonist used to treat both alcohol use disorder and opioid dependence. Available as a daily oral tablet or monthly extended-release injection, it blocks opioid receptors to reduce cravings and prevent relapse.
Treatment landscape in Oklahoma:
- SoonerCare covers addiction treatment
- Growing treatment infrastructure
- Faith-based and traditional recovery options
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Naltrexone providers in Oklahoma
Oklahoma City · 7 centers

HOPE Community Services Inc
Oklahoma City, OK
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North Oklahoma County MH Center Inc
Oklahoma City, OK
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Veterans Affairs Medical Center
Oklahoma City, OK
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TRC The Recovery Center
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Tulsa · 4 centers

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McAlester · 3 centers

Oklahoma Treatment Services LLC
McAlester, OK
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Stigler Health and Wellness Inc
McAlester, OK
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Carl Albert
McAlester, OK
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Lawton · 2 centers

Catalyst
Lawton, OK
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Jim Taliaferro CMHC
Lawton, OK
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Muskogee · 2 centers

Eastern Oklahoma VA Healthcare System
Muskogee, OK
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Green Country Behavioral Hlth Servs
Muskogee, OK
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Stigler · 2 centers

Stigler Health and Wellness Center
Stigler, OK
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Carl Albert
Stigler, OK
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Tahlequah · 2 centers

Northeastern Health System
Tahlequah, OK
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CREOKS Health Services
Tahlequah, OK
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Alva · 1 center

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Anadarko · 1 center

Kiowa Alcohol Drug
Anadarko, OK
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Ardmore · 1 center

Lighthouse Behavioral Wellness Centers
Ardmore, OK
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Chickasha · 1 center

Red Rock Behavioral Health Services
Chickasha, OK
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Cleveland · 1 center

Grand Lake Mental Health Center Inc
Cleveland, OK
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Colcord · 1 center

Grand Lake Mental Health Center Inc
Colcord, OK
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Cushing · 1 center
Edmond · 1 center

Arcadia Trails Integris Center for
Edmond, OK
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El Reno · 1 center

Red Rock Behavioral Health Services
El Reno, OK
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Elk City · 1 center

Red Rock Behavioral Health Services
Elk City, OK
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Enid · 1 center

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Eufaula · 1 center
Fairview · 1 center

Northwest Center for Behavioral Health
Fairview, OK
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Fort Supply · 1 center
Guymon · 1 center

Northwest Center for Behavioral Health
Guymon, OK
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Hobart · 1 center

Red Rock Behavioral Health Services
Hobart, OK
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Holdenville · 1 center

Carl Albert
Holdenville, OK
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Idabel · 1 center

Carl Albert
Idabel, OK
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Kingfisher · 1 center

Red Rock Behavioral Health Services
Kingfisher, OK
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Konawa · 1 center

Valliant House Konawa
Konawa, OK
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Norman · 1 center
Ponca City · 1 center
Poteau · 1 center
Sallisaw · 1 center

CREOKS Health Services
Sallisaw, OK
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Stillwater · 1 center

Payne County
Stillwater, OK
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Stilwell · 1 center

CREOKS Health Services
Stilwell, OK
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Watonga · 1 center

Red Rock Behavioral Health Services
Watonga, OK
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Weatherford · 1 center

Red Rock Behavioral Health Services
Weatherford, OK
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Wilburton · 1 center

Stigler Health and Wellness Center
Wilburton, OK
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Woodward · 1 center

Northwest Center for Behavioral Health
Woodward, OK
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Showing 52 of 76 naltrexone providers in Oklahoma. Browse all centers in Oklahoma
SoonerCare
SoonerCare covers buprenorphine and naltrexone; methadone treatment is covered at licensed OTPs, primarily in Oklahoma City and Tulsa.
State regulations
Oklahoma Department of Mental Health and Substance Abuse Services (ODMHSAS) licenses OTPs and funds the Oklahoma Opioid Helpline.
- Cash or self-payment46
- Medicaid46
- Federal, or any government funding for substance use treatment programs42
- Private health insurance37
- Medicare36
- Federal military insurance (e.g., TRICARE)34
- Outpatient48
- Regular outpatient treatment48
- Outpatient methadone/buprenorphine or naltrexone treatment38
- Intensive outpatient treatment19
- Residential/24-hour residential8
Frequently Asked Questions About Naltrexone in Oklahoma
Do I have to stop using opioids before starting naltrexone?
For methadone and buprenorphine, continued opioid use during induction is common and expected; the medication itself helps stop use. For naltrexone, however, you must complete a 7–14 day opioid-free period first. Your Oklahoma clinician will tailor the induction based on your medication.
Is the first visit to a naltrexone provider free?
Some Oklahoma programs offer a free screening or phone intake; others charge an initial assessment fee ($100–$300 self-pay). Federally qualified health centers often waive the first visit. Ask up front about assessment fees when you schedule your appointment.
Does SoonerCare cover SAMHSA-required counseling along with naltrexone?
Yes. SoonerCare covers the mandated counseling component for MAT — individual therapy, group sessions, and care coordination — at participating Oklahoma clinics. Reimbursement for peer-support specialists is also available under the state plan.
Will UnitedHealthcare or Aetna cover naltrexone?
Yes. Both UnitedHealthcare and Aetna cover the MAT benefit in Oklahoma, including naltrexone. Verify in-network providers and whether long-acting injectables require prior authorization; patient-advocate lines can confirm network status before you schedule.
Are there license caps or certificate-of-need rules for new naltrexone providers in Oklahoma?
Oklahoma applies state-specific licensure review for new OTPs; some states also require a certificate-of-need demonstrating unmet demand. Existing buprenorphine prescribers do not face these caps — only methadone OTPs are subject to location-specific licensure review.
Is it harder to quit methadone than buprenorphine?
Methadone tapering generally takes longer than buprenorphine because of its long half-life and higher cumulative-dose equilibrium. Most Oklahoma clinicians taper methadone over 6–12 months or longer. Buprenorphine tapers often complete in 3–6 months for stable patients.
How do I start naltrexone treatment in Oklahoma?
Call a naltrexone clinic directly, SAMHSA’s national helpline (1-800-662-4357), or 988 for urgent help. Most Oklahoma naltrexone providers offer same-day or next-business-day intake; the intake visit includes an assessment and your first dose or prescription.
Will I feel high or sedated after the first naltrexone dose?
Most patients feel calm relief of withdrawal rather than euphoria. Mild drowsiness is common the first day; avoid driving or operating machinery until you know how you react. Severe sedation is rare and warrants a call to the Oklahoma clinic.
Is constipation on naltrexone a serious problem?
Constipation is one of the most common and persistent naltrexone side effects. Daily fluids, fiber, stool softeners, and an over-the-counter laxative like polyethylene glycol are first-line. If severe, your Oklahoma clinician may prescribe a peripherally acting opioid-receptor antagonist.
Can I deliver at any Oklahoma hospital if I’m on naltrexone?
Yes. All Oklahoma birthing hospitals are equipped to care for MAT patients. Choosing a hospital with a dedicated perinatal-addiction protocol — often larger urban hospitals — can improve experience. Discuss delivery location with your OB and MAT team well before the due date.
Will my counseling sessions be confidential?
Yes — counseling records are protected by 42 CFR Part 2 and HIPAA. The counselor cannot disclose your MAT status or session content to family, employer, or law enforcement without your specific written consent or a narrowly tailored court order.
Can I keep my naltrexone treatment private from my health-insurance company?
If you use insurance, the insurer sees billed services (including MAT). They cannot share that with your employer or family. If you strongly value privacy from insurance, self-pay is the only fully insulated option.
Other Treatment Options in Oklahoma
Naltrexone Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)



