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Medically Reviewed Content
Updated: April 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers in Oklahoma

Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026

Our directory lists 126 MAT programs across Oklahoma, with the largest concentrations in Oklahoma City (11), Tulsa (8) and Stillwater (3).

Medication-Assisted Treatment (MAT) combines FDA-approved medications — methadone, buprenorphine, and naltrexone — with counseling and behavioral therapies for comprehensive addiction care. MAT is the evidence-based gold standard for opioid and alcohol use disorders.

Treatment landscape in Oklahoma:

  • SoonerCare covers addiction treatment
  • Growing treatment infrastructure
  • Faith-based and traditional recovery options

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MAT programs in Oklahoma

Filters:

Oklahoma City · 11 centers

Cope Inc - Facility Image

Cope Inc

Oklahoma City, OK

Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Hefner Comprehensive Treatment Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatment
HOPE Community Services Inc - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Tulsa · 8 centers

Tulsa Comprehensive Treatment Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Tulsa VA Outpatient Clinic - Facility Image
Insurance Accepted$$

Services:

Substance use treatment
Keetoowah Cherokee Trt Servs - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

McAlester · 3 centers

Oklahoma Treatment Services LLC - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Stigler Health and Wellness Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home
Placeholder image

Carl Albert

McAlester, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Stillwater · 3 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

Payne County

Stillwater, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Ardmore · 2 centers

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Bartlesville · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Oklahoma Treatment Services LLC - Facility Image
Insurance Accepted$$

Services:

Substance use treatment

Claremore · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Human Skills and Resources Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Jay · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home

Kansas · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Lawton · 2 centers

Catalyst - Facility Image

Catalyst

Lawton, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Miami · 2 centers

Northeastern Oklahoma Council on - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatment

Muskogee · 2 centers

Eastern Oklahoma VA Healthcare System - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment
Green Country Behavioral Hlth Servs - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Ponca City · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Oklahoma Treatment Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatment

Stigler · 2 centers

Stigler Health and Wellness Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

Carl Albert

Stigler, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Tahlequah · 2 centers

Northeastern Health System - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Vinita · 2 centers

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatment

Alva · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Anadarko · 1 center

Placeholder image

Kiowa Alcohol Drug

Anadarko, OK

$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Blackwell · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Canadian · 1 center

Narconon of Oklahoma Inc - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home

Chickasha · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Cleveland · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Colcord · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Commerce · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatment

Cushing · 1 center

Valley Hope - Facility Image

Valley Hope

Cushing, OK

Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Edmond · 1 center

Arcadia Trails Integris Center for - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

El Reno · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Elk City · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Enid · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Eufaula · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatment

Fairview · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Fort Supply · 1 center

Placeholder image
Insurance Accepted$$

Services:

Detoxification

Grove · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Guymon · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hobart · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Holdenville · 1 center

Placeholder image

Carl Albert

Holdenville, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Idabel · 1 center

Placeholder image

Carl Albert

Idabel, OK

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Kingfisher · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Konawa · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Maud · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

McLoud · 1 center

Kickapoo Tribe of Oklahoma - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Mead · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Norman · 1 center

Virtue Center - Facility Image

Virtue Center

Norman, OK

Insurance Accepted$$

Services:

Substance use treatment

Nowata · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Pawhuska · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Perry · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Poteau · 1 center

Stigler Health and Wellness Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatment

Pryor · 1 center

Grand Lake Mental Health Center Inc - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Roland · 1 center

Rightway Medical of Roland - Facility Image
Insurance Accepted$$

Services:

Substance use treatment

Sallisaw · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Sapulpa · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Stilwell · 1 center

CREOKS Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Stroud · 1 center

Sac and Fox Nation - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Watonga · 1 center

Red Rock Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Weatherford · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Wilburton · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Woodward · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Wyandotte · 1 center

Lost River Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Showing 91 of 126 MAT programs in Oklahoma. Browse all centers in Oklahoma

Coverage & Regulations in Oklahoma

SoonerCare

SoonerCare covers buprenorphine and naltrexone; methadone treatment is covered at licensed OTPs, primarily in Oklahoma City and Tulsa.

State regulations

Oklahoma Department of Mental Health and Substance Abuse Services (ODMHSAS) licenses OTPs and funds the Oklahoma Opioid Helpline.

SAMHSA National Helpline: 1-800-662-4357Crisis: 988
Commonly Accepted Insurance
  • Cash or self-payment83
  • Medicaid83
  • Private health insurance66
  • Medicare61
  • Federal, or any government funding for substance use treatment programs55
  • Federal military insurance (e.g., TRICARE)53
Available Settings
  • Outpatient83
  • Regular outpatient treatment81
  • Outpatient methadone/buprenorphine or naltrexone treatment71
  • Outpatient detoxification30
  • Intensive outpatient treatment25

Frequently Asked Questions About MAT in Oklahoma

Can undocumented immigrants access mat in Oklahoma?

Many Oklahoma providers accept self-pay, sliding-fee, or grant-funded patients regardless of immigration status. Federally funded community health centers and some SoonerCare-contracted clinics offer MAT on a sliding scale. Providers are not required to report immigration status.

Does the cost of mat in Oklahoma change over time?

Yes. Oklahoma MAT costs typically decrease as you stabilize — fewer in-person dosing visits, less frequent drug testing, and the option for take-home doses for methadone patients. Naltrexone patients often shift from monthly visits to quarterly visits once stable.

Can SoonerCare pay retroactively for MAT I started before enrollment?

Yes — SoonerCare can pay retroactively for up to 3 months of prior treatment in most cases, provided you were eligible during that period. Save all receipts and itemized statements from MAT programs and submit them to the Medicaid enrollment caseworker.

Does COBRA cover mat in Oklahoma?

Yes. COBRA continues your former employer’s health plan unchanged for up to 18 months, including MAT benefits. The monthly COBRA premium is higher than a marketplace plan for most people; explore Marketplace options too before the 60-day COBRA deadline.

Is mat treatment legal and regulated in Oklahoma?

Yes. mat is a federally approved medication used legally across Oklahoma. Methadone is dispensed only at SAMHSA-certified Opioid Treatment Programs (OTPs); buprenorphine is prescribed by licensed clinicians; naltrexone has no prescriber waiver requirement. State licensing agencies oversee all MAT programs.

Can I take mat while travelling outside Oklahoma?

Yes. Buprenorphine and naltrexone prescriptions travel with you. For methadone, your clinic coordinates with an out-of-state guest-dosing OTP; plan at least 2 weeks ahead for domestic travel, longer for international. Ask the clinic about guest-dosing letters.

Can I switch Oklahoma mat providers later if this one isn’t a fit?

Yes. Transferring to a different Oklahoma provider is routine; the new clinic will request records with your consent and continue your current dose. There is no penalty for switching providers — clinical compatibility matters.

Can I drive myself home from the first mat dose in Oklahoma?

Oklahoma programs generally recommend arranging a ride for the first induction visit, since initial drowsiness is common. After the first 1–2 weeks at a stable dose, patients typically resume driving and most daily activities without restriction.

Does mat interact with other medications?

Yes. Benzodiazepines, alcohol, and some sleep medications significantly increase sedation risk. HIV medications and certain antibiotics can alter methadone levels. Always share your full medication list with the Oklahoma MAT clinician so interactions can be managed.

Will pediatricians in Oklahoma know how to care for my MAT-exposed baby?

Yes. Oklahoma pediatricians and neonatologists receive training on caring for infants with prenatal opioid exposure. Eat, Sleep, Console protocols, parental involvement, and compassionate postpartum care are standard. Share your MAT history openly so the team can tailor monitoring.

Does SoonerCare cover counseling along with mat?

Yes. SoonerCare covers individual therapy, group sessions, and care coordination at Oklahoma MAT clinics without separate deductibles in most plans. Peer-recovery support services are also covered in Oklahoma.

Are group-counseling sessions confidential?

Yes. Group members sign confidentiality agreements, and the clinician protects group content under 42 CFR Part 2. Enforcement between group members depends on honor among peers, but legal protections limit disclosure by the clinic or clinician.

Other Treatment Options in Oklahoma

Medication-Assisted Treatment in Other States

Medically Reviewed Updated April 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)