Medication-Assisted Treatment (MAT) Centers in Oklahoma
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 126 MAT programs across Oklahoma, with the largest concentrations in Oklahoma City (11), Tulsa (8) and Stillwater (3).
Medication-Assisted Treatment (MAT) combines FDA-approved medications — methadone, buprenorphine, and naltrexone — with counseling and behavioral therapies for comprehensive addiction care. MAT is the evidence-based gold standard for opioid and alcohol use disorders.
Treatment landscape in Oklahoma:
- SoonerCare covers addiction treatment
- Growing treatment infrastructure
- Faith-based and traditional recovery options
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MAT programs in Oklahoma
Oklahoma City · 11 centers

Cope Inc
Oklahoma City, OK
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Hefner Comprehensive Treatment Center
Oklahoma City, OK
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HOPE Community Services Inc
Oklahoma City, OK
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North Oklahoma County MH Center Inc
Oklahoma City, OK
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Oklahoma City Comprehensive Trt Center
Oklahoma City, OK
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Veterans Affairs Medical Center
Oklahoma City, OK
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TRC The Recovery Center
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Red Rock Behavioral Health Services
Oklahoma City, OK
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Tulsa · 8 centers

Tulsa Comprehensive Treatment Center
Tulsa, OK
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Keetoowah Cherokee Trt Servs
Tulsa, OK
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Human Skills and Resources Inc
Tulsa, OK
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McAlester · 3 centers

Oklahoma Treatment Services LLC
McAlester, OK
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Stigler Health and Wellness Inc
McAlester, OK
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Carl Albert
McAlester, OK
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Stillwater · 3 centers

Grand Lake Mental Health Center Inc
Stillwater, OK
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Grand Lake Mental Health Center Inc
Stillwater, OK
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Payne County
Stillwater, OK
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Ardmore · 2 centers

Lighthouse Behavioral Wellness Centers
Ardmore, OK
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Southern Oklahoma Treatment Services
Ardmore, OK
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Bartlesville · 2 centers

Grand Lake Mental Health Center Inc
Bartlesville, OK
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Claremore · 2 centers

Grand Lake Mental Health Center Inc
Claremore, OK
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Human Skills and Resources Inc
Claremore, OK
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Jay · 2 centers

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Kansas · 2 centers

Grand Lake Mental Health Center Inc
Kansas, OK
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Grand Lake Mental Health Center Inc
Kansas, OK
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Lawton · 2 centers

Catalyst
Lawton, OK
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Jim Taliaferro CMHC
Lawton, OK
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Miami · 2 centers

Northeastern Oklahoma Council on
Miami, OK
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Muskogee · 2 centers

Eastern Oklahoma VA Healthcare System
Muskogee, OK
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Green Country Behavioral Hlth Servs
Muskogee, OK
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Ponca City · 2 centers

Grand Lake Mental Health Center Inc
Ponca City, OK
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Stigler · 2 centers

Stigler Health and Wellness Center
Stigler, OK
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Carl Albert
Stigler, OK
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Tahlequah · 2 centers

Northeastern Health System
Tahlequah, OK
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CREOKS Health Services
Tahlequah, OK
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Vinita · 2 centers

Grand Lake Mental Health Center Inc
Vinita, OK
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Alva · 1 center

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Anadarko · 1 center

Kiowa Alcohol Drug
Anadarko, OK
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Blackwell · 1 center

Grand Lake Mental Health Center Inc
Blackwell, OK
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Canadian · 1 center

Narconon of Oklahoma Inc
Canadian, OK
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Chickasha · 1 center

Red Rock Behavioral Health Services
Chickasha, OK
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Cleveland · 1 center

Grand Lake Mental Health Center Inc
Cleveland, OK
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Colcord · 1 center

Grand Lake Mental Health Center Inc
Colcord, OK
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Commerce · 1 center
Cushing · 1 center
Edmond · 1 center

Arcadia Trails Integris Center for
Edmond, OK
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El Reno · 1 center

Red Rock Behavioral Health Services
El Reno, OK
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Elk City · 1 center

Red Rock Behavioral Health Services
Elk City, OK
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Enid · 1 center

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Eufaula · 1 center
Fairview · 1 center

Northwest Center for Behavioral Health
Fairview, OK
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Fort Supply · 1 center
Grove · 1 center

Grand Lake Mental Health Center Inc
Grove, OK
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Guymon · 1 center

Northwest Center for Behavioral Health
Guymon, OK
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Hobart · 1 center

Red Rock Behavioral Health Services
Hobart, OK
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Holdenville · 1 center

Carl Albert
Holdenville, OK
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Idabel · 1 center

Carl Albert
Idabel, OK
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Kingfisher · 1 center

Red Rock Behavioral Health Services
Kingfisher, OK
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Konawa · 1 center

Valliant House Konawa
Konawa, OK
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Maud · 1 center

Clay Crossing Foundation Inc
Maud, OK
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McLoud · 1 center

Kickapoo Tribe of Oklahoma
McLoud, OK
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Mead · 1 center

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Norman · 1 center
Nowata · 1 center

Grand Lake Mental Health Center Inc
Nowata, OK
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Pawhuska · 1 center

Grand Lake Mental Health Center Inc
Pawhuska, OK
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Perry · 1 center

Grand Lake Mental Health Center Inc
Perry, OK
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Poteau · 1 center
Pryor · 1 center

Grand Lake Mental Health Center Inc
Pryor, OK
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Roland · 1 center
Sallisaw · 1 center

CREOKS Health Services
Sallisaw, OK
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Sapulpa · 1 center

Human Skills and Resources Inc
Sapulpa, OK
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Stilwell · 1 center

CREOKS Health Services
Stilwell, OK
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Stroud · 1 center

Sac and Fox Nation
Stroud, OK
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Watonga · 1 center

Red Rock Behavioral Health Services
Watonga, OK
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Weatherford · 1 center

Red Rock Behavioral Health Services
Weatherford, OK
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Wilburton · 1 center

Stigler Health and Wellness Center
Wilburton, OK
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Woodward · 1 center

Northwest Center for Behavioral Health
Woodward, OK
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Wyandotte · 1 center

Lost River Treatment Center
Wyandotte, OK
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Showing 91 of 126 MAT programs in Oklahoma. Browse all centers in Oklahoma
SoonerCare
SoonerCare covers buprenorphine and naltrexone; methadone treatment is covered at licensed OTPs, primarily in Oklahoma City and Tulsa.
State regulations
Oklahoma Department of Mental Health and Substance Abuse Services (ODMHSAS) licenses OTPs and funds the Oklahoma Opioid Helpline.
- Cash or self-payment83
- Medicaid83
- Private health insurance66
- Medicare61
- Federal, or any government funding for substance use treatment programs55
- Federal military insurance (e.g., TRICARE)53
- Outpatient83
- Regular outpatient treatment81
- Outpatient methadone/buprenorphine or naltrexone treatment71
- Outpatient detoxification30
- Intensive outpatient treatment25
Frequently Asked Questions About MAT in Oklahoma
Can undocumented immigrants access mat in Oklahoma?
Many Oklahoma providers accept self-pay, sliding-fee, or grant-funded patients regardless of immigration status. Federally funded community health centers and some SoonerCare-contracted clinics offer MAT on a sliding scale. Providers are not required to report immigration status.
Does the cost of mat in Oklahoma change over time?
Yes. Oklahoma MAT costs typically decrease as you stabilize — fewer in-person dosing visits, less frequent drug testing, and the option for take-home doses for methadone patients. Naltrexone patients often shift from monthly visits to quarterly visits once stable.
Can SoonerCare pay retroactively for MAT I started before enrollment?
Yes — SoonerCare can pay retroactively for up to 3 months of prior treatment in most cases, provided you were eligible during that period. Save all receipts and itemized statements from MAT programs and submit them to the Medicaid enrollment caseworker.
Does COBRA cover mat in Oklahoma?
Yes. COBRA continues your former employer’s health plan unchanged for up to 18 months, including MAT benefits. The monthly COBRA premium is higher than a marketplace plan for most people; explore Marketplace options too before the 60-day COBRA deadline.
Is mat treatment legal and regulated in Oklahoma?
Yes. mat is a federally approved medication used legally across Oklahoma. Methadone is dispensed only at SAMHSA-certified Opioid Treatment Programs (OTPs); buprenorphine is prescribed by licensed clinicians; naltrexone has no prescriber waiver requirement. State licensing agencies oversee all MAT programs.
Can I take mat while travelling outside Oklahoma?
Yes. Buprenorphine and naltrexone prescriptions travel with you. For methadone, your clinic coordinates with an out-of-state guest-dosing OTP; plan at least 2 weeks ahead for domestic travel, longer for international. Ask the clinic about guest-dosing letters.
Can I switch Oklahoma mat providers later if this one isn’t a fit?
Yes. Transferring to a different Oklahoma provider is routine; the new clinic will request records with your consent and continue your current dose. There is no penalty for switching providers — clinical compatibility matters.
Can I drive myself home from the first mat dose in Oklahoma?
Oklahoma programs generally recommend arranging a ride for the first induction visit, since initial drowsiness is common. After the first 1–2 weeks at a stable dose, patients typically resume driving and most daily activities without restriction.
Does mat interact with other medications?
Yes. Benzodiazepines, alcohol, and some sleep medications significantly increase sedation risk. HIV medications and certain antibiotics can alter methadone levels. Always share your full medication list with the Oklahoma MAT clinician so interactions can be managed.
Will pediatricians in Oklahoma know how to care for my MAT-exposed baby?
Yes. Oklahoma pediatricians and neonatologists receive training on caring for infants with prenatal opioid exposure. Eat, Sleep, Console protocols, parental involvement, and compassionate postpartum care are standard. Share your MAT history openly so the team can tailor monitoring.
Does SoonerCare cover counseling along with mat?
Yes. SoonerCare covers individual therapy, group sessions, and care coordination at Oklahoma MAT clinics without separate deductibles in most plans. Peer-recovery support services are also covered in Oklahoma.
Are group-counseling sessions confidential?
Yes. Group members sign confidentiality agreements, and the clinician protects group content under 42 CFR Part 2. Enforcement between group members depends on honor among peers, but legal protections limit disclosure by the clinic or clinician.
Other Treatment Options in Oklahoma
Medication-Assisted Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)






