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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Family Self Help Center Inc

The Family Self Help Center Inc, located in Joplin, MO, specializes in providing tailored substance use treatment for adult women who have experienced domestic violence, intimate partner violence, and sexual abuse. The center offers an array of services, including intensive outpatient treatment, outpatient day programs, and partial hospitalization, all grounded in evidence-based practices such as cognitive behavioral therapy, anger management, and brief interventions. Designed to cater to adults, seniors, and young adults, this facility creates a nurturing atmosphere for women seeking thorough support. Emphasizing personalized care and high standards, Family Self Help Center Inc is dedicated to meeting the specific needs of women facing challenges related to substance use and trauma.

Family Guidance Centers Inc

Family Guidance Centers Inc. in Joliet, Illinois, specializes in outpatient services for adults navigating the complexities of substance use disorders, particularly when co-occurring with significant mental health challenges. Their treatment approach incorporates evidence-based modalities such as cognitive behavioral therapy, motivational interviewing, and strategies for maintaining sobriety. The center also extends its reach to adolescents and individuals involved in the criminal justice system through tailored programs. Prioritizing a personalized treatment experience, Family Guidance Centers Inc. accommodates both men and women, offering medication-assisted treatment options including methadone, buprenorphine, or naltrexone. They are equipped to provide thorough care for those requiring assistance with substance abuse or dual diagnoses.

Family Guidance Centers Inc

Family Guidance Centers Inc in Joliet, IL, delivers thorough substance abuse care for adults and young adults. They offer intensive outpatient services, standard outpatient programs, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing cognitive behavioral techniques, motivational interviewing, and relapse prevention methods, this facility provides tailored support for all clients. They also feature a dedicated program for individuals involved with the criminal justice system. Clients will find evidence-based methods and empathetic assistance, establishing Family Guidance Centers Inc as a reliable provider of effective recovery solutions in Joliet.

Family Guidance Centers Inc

Family Guidance Centers Inc in Chicago, IL, delivers thorough substance use recovery services for adults and adolescents. Available programs include standard outpatient care, as well as specialized services utilizing methadone, buprenorphine, or naltrexone. The center employs therapeutic techniques such as cognitive behavioral therapy, motivational interviewing, and relapse prevention. Emphasizing personalized support, Family Guidance Centers Inc crafts treatment paths to suit individual client circumstances. They serve both men and women, fostering a welcoming atmosphere. For those pursuing scientifically supported addiction treatment, this establishment offers excellent care adapted to each person.

Family Medicine and Rehab Center

In Morehead City, NC, the Family Medicine and Rehab Center provides outpatient care for substance abuse in both adolescents and adults. Their services extend to individuals managing serious mental health conditions alongside addiction. They have distinct programs for active duty military members, adult men, and women. Utilizing methods like 12-step facilitation, anger management training, and brief intervention strategies, the center serves a diverse population, including older adults, of all genders. They offer outpatient treatment with methadone, buprenorphine, or naltrexone, aiming to deliver thorough recovery support.

Family Medicine and Rehab Center

The Family Medicine and Rehab Center, situated in Goldsboro, NC, provides outpatient care for individuals struggling with substance use. Their expertise lies in addressing co-occurring conditions, specifically substance use disorders alongside severe mental health challenges in adults or significant emotional issues in children. The treatment approach incorporates elements like 12-step facilitation, anger management techniques, and brief intervention strategies. The center is equipped to serve various groups with specialized programs for active military personnel, adult men, and adult women. They offer medication-assisted treatment options including methadone, buprenorphine, or naltrexone, alongside standard outpatient rehabilitation services, ensuring comprehensive support for all clients.

Family Healthcare Center at SSTAR

Family Healthcare Center at SSTAR, located in Fall River, MA, provides an array of specialized programs to address substance use and concurrent mental health issues. Their offerings include outpatient and intensive outpatient services that employ evidence-based methods like cognitive behavioral therapy, motivational interviewing, and contingency management. The center caters to diverse populations, creating customized programs for active duty military personnel, teenagers, and adult males, while also ensuring individualized support for adults and seniors of every gender. Their commitment to high-quality care and a wide variety of treatment options positions this facility as an essential resource for individuals in need of extensive rehabilitation services in the Fall River community.

Family Guidance Centers Inc

Family Guidance Centers Inc. in Quincy, IL, provides outpatient addiction recovery programs for adults and young adults. Their specialized interventions include cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. Clients receive personalized care through treatment plans developed to address their specific circumstances. The center offers outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, in addition to standard outpatient services, promoting ongoing support for recovery. This facility serves both men and women, emphasizing high-quality assistance for individuals overcoming substance use challenges.

Family Health Centers of San Diego Inc

Family Health Centers of San Diego Inc., situated in San Diego, CA, delivers a full spectrum of care for substance use disorders. Services include intensive outpatient, standard outpatient, and regular outpatient treatment options for adults and adolescents. This facility specializes in cognitive behavioral therapy, anger management, and brief intervention techniques, serving individuals with co-occurring mental health conditions. Tailored programs are offered to clients with histories of trauma and those in the LGBTQ community. The center provides dedicated support for both male and female patients addressing substance use and mental health concerns.

Family Health Centers of San Diego Inc

Family Health Centers of San Diego Inc, situated in Imperial Beach, CA, provides extensive support for individuals struggling with substance use disorders. This center specializes in addressing co-occurring mental health conditions alongside substance dependence for both adults and young adults. Their treatment options include structured outpatient and intensive outpatient programs, with provisions for methadone and buprenorphine services. Employing proven therapeutic methods such as cognitive behavioral therapy and contingency management, Family Health Centers of San Diego Inc is equipped to support active duty military members, adult men, and women. They are committed to delivering tailored care, recognizing the importance of gender-specific and age-appropriate interventions to foster successful recovery.

Family Guidance Centers Inc

Family Guidance Centers Inc, located in Harvey, IL, provides outpatient treatment for substance use issues and specialized support for adults with co-occurring disorders related to serious mental health challenges, as well as emotional issues in children. The facility offers outpatient options for methadone, buprenorphine, and naltrexone treatments, employing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies to prevent relapse. Committed to personalized treatment, the center serves adults and young adults of any gender. Family Guidance Centers Inc is recognized for its customized care approach, making it an excellent option for individuals seeking effective and tailored addiction recovery services.

Family Guidance Centers Inc

Family Guidance Centers Inc. located in Des Plaines, IL, provides a comprehensive outpatient program for adults struggling with substance use disorders, particularly those with co-occurring mental health conditions. They also offer specialized services for children experiencing significant emotional challenges. The center administers medication-assisted treatment, including methadone, buprenorphine, and naltrexone, alongside general outpatient support. Their therapeutic methods incorporate evidence-based practices like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, all customized to meet the unique needs of each person. Open to adults and young adults across the gender spectrum, Family Guidance Centers Inc. is dedicated to delivering personalized care focused on achieving sustained recovery.

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Family Guidance Centers Inc, located in Chicago, IL, provides outpatient treatment for substance use disorders among both adults and young adults who also face significant mental health challenges. This center emphasizes specialized approaches, utilizing methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. With an emphasis on personalized treatment plans, the facility welcomes both men and women on their journey to recovery. The program also offers outpatient options for methadone, buprenorphine, or naltrexone. Clients can anticipate high-quality, gender-sensitive care that caters to the individual needs of each person, making it an excellent option for those seeking customized treatment approaches.

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Family Guidance Centers Inc located in Springfield, IL, delivers a wide range of treatment options for substance use disorders, including long-term residential programs, outpatient services, and specialized outpatient programs using methadone, buprenorphine, or naltrexone. Emphasizing methods such as 12-step support, cognitive behavioral therapy, and motivational interviewing, the center serves both adult men and women, as well as individuals facing dual diagnoses of mental and substance use disorders. With a strong focus on care for adults and young adults, Family Guidance Centers Inc features gender-specific treatments designed for both men and women. The center is committed to offering exceptional support and resources for those on their path to recovery and a clean lifestyle.

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Family Guidance Centers Inc. in Aurora, IL, delivers outpatient care for individuals struggling with substance use disorders and co-occurring mental health conditions. This center extends specialized support to those involved with the criminal justice system. Their therapeutic methods encompass cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. In addition to standard outpatient services, they offer medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Family Guidance Centers Inc. provides a welcoming and effective rehabilitation experience for adult men and women.

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Family Guidance Centers Inc. in Chicago, IL, specializes in outpatient addiction recovery, emphasizing personalized treatment plans. They offer medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside various outpatient programs. Their approach incorporates evidence-based therapies such as cognitive behavioral therapy, motivational interviewing, and strategies for relapse prevention. These customized services are available for adults and young adults of any gender. The center distinguishes itself through its dedication to tailored care and proven methods for overcoming substance dependence, making Family Guidance Centers Inc. a trusted resource in Chicago for those prioritizing individualized support in their recovery journey.

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Family Guidance Centers Inc, situated in Manteno, IL, delivers a complete spectrum of addiction recovery programs designed for adults and adolescents. Their offerings include detoxification, substance abuse therapy, temporary housing, and sober living arrangements. The center features extended residential stays, outpatient programs, and outpatient medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Employing methodologies such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this institution serves adult men and women, including individuals with a history of trauma. Prioritizing personalized care and scientifically-backed methods, Family Guidance Centers Inc guarantees effective treatment for both male and female individuals pursuing freedom from addiction.

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Family Medical Centers in Ironton, OH, delivers extensive outpatient care tailored for adults facing substance use disorders and concurrent serious mental health issues, along with support for children's emotional challenges. This center features targeted programs for both adult males and females, as well as those who have undergone trauma. Treatment strategies encompass anger management, short-term interventions, and cognitive behavioral therapy. The services provided are designed for adults and young adults, ensuring distinct programs for each gender. With an emphasis on high-quality treatment and multiple outpatient options, including methadone/buprenorphine or naltrexone therapies, this center is committed to guiding individuals on their recovery journey.

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The Family Mental Health Clinic, situated in Hartsdale, NY, is dedicated to providing expert care for individuals struggling with substance use disorders and those experiencing co-occurring mental health conditions. They also address emotional challenges in young individuals. Their treatment spectrum includes intensive outpatient, outpatient, and medication-assisted treatment such as methadone, buprenorphine, or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, the clinic crafts personalized recovery plans. The facility offers specialized tracks for teenagers, adult men, and women, supporting both male and female clients of all ages in their journey toward healing.

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Steubenville, OH

Family Recovery Center, located in Steubenville, OH, specializes in various treatment options for individuals dealing with substance use issues alongside mental health challenges. The center offers a range of services including intensive outpatient programs, standard outpatient care, as well as methadone/buprenorphine and naltrexone treatments. Emphasizing a blend of 12-step support, anger management techniques, and brief intervention strategies, the center serves a diverse population including adolescents, adult men, and women. Catering to people of all ages and genders, Family Recovery Center is dedicated to providing high-quality, personalized care, making it a reliable option for those in need of thorough rehabilitation support.

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Situated in Lisbon, OH, the Family Recovery Center delivers an extensive range of treatment options for adults dealing with concurrent severe mental health issues and substance use disorders. This center features a variety of programs, including intensive outpatient services, standard outpatient support, and tailored treatments involving medications such as methadone, buprenorphine, or naltrexone. Emphasizing approaches like 12-step support, anger management, and brief interventions, the center serves individuals of all ages and gender identities. It also offers specialized programs for teenagers, adult males, and survivors of domestic abuse, making it a distinctive resource. The Family Recovery Center is committed to providing high-quality care and support for individuals striving to overcome addiction and mental health obstacles.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)