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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Aleda E Lutz VAMC

Situated in Saginaw, MI, the Aleda E Lutz VAMC stands out as a premier rehabilitation center dedicated to assisting adults and young adults facing challenges related to substance use and accompanying mental health conditions. The center features both intensive outpatient and outpatient detox programs, employing proven methods including cognitive behavioral therapy and anger management techniques. With a particular emphasis on adult women, survivors of domestic violence, and those who have faced sexual abuse, this facility provides customized support for its clients. Both men and women can access a range of comprehensive treatment solutions that emphasize high-quality, compassionate care.

Alexian Brothers BH Hosp

Situated in Schaumburg, IL, the Alexian Brothers BH Hosp delivers thorough addiction recovery services for both adults and children facing substance misuse and concurrent mental health challenges. The center features specialized programs catering to adolescents, adult males, and individuals with dual diagnoses, offering inpatient detox and treatment grounded in evidence-based methodologies such as 12-step facilitation, brief interventions, and cognitive behavioral therapy. Customized treatment plans are developed for male and female adults and seniors, ensuring personalized care. The facility's dedication to high-quality treatment and its emphasis on meeting individual needs position it as a reliable option for those in search of effective rehabilitation support.

Align Recovery Centers

Align Recovery Centers located in Sonoma, CA, provides a wide range of addiction treatment services aimed at adults and young adults struggling with substance abuse issues and co-existing mental health challenges. The facility features hospital inpatient detox and treatment options, along with specific programs designed for active-duty military members, as well as adult men and women. Emphasizing approaches such as 12-step facilitation, anger management, and cognitive behavioral therapy, the center customizes its treatment plans to meet the unique needs of each individual. Catering to both male and female clients, Align Recovery Centers is dedicated to offering top-tier care in a nurturing environment to support clients on their path to sustainable recovery.

Alexian Brothers/Foglia Family
Elk Grove Village, IL

Situated in Elk Grove Village, IL, the Alexian Brothers/Foglia Family center delivers exceptional substance use rehabilitation in a residential environment. The facility specializes in short-term residential programs that emphasize 12-step facilitation, brief interventions, and cognitive behavioral therapy. Focusing on individualized care, the center serves both adults and young adults across all gender identities. Its distinctive methodology guarantees customized treatment strategies for everyone, ensuring superior care and support during the recovery process. If you are looking for personalized and effective addiction treatment, this center is committed to guiding you towards lasting sobriety.

Aldie Counseling Center

Nestled in Doylestown, PA, Aldie Counseling Center distinguishes itself with comprehensive programs for individuals of all ages grappling with substance use disorders and co-occurring mental health conditions. The center emphasizes intensive outpatient and standard outpatient services, employing evidence-based therapies like 12-step facilitation, cognitive behavioral therapy, and brief intervention strategies. Aldie Counseling Center offers specialized support for active duty military members, teenagers, and adult men, ensuring a gender-inclusive approach to recovery for both male and female clients facing addiction and mental health struggles.

Alfre Inc
Morristown, NJ

Alfre Inc, located in Morristown, NJ, is a leading facility dedicated to assisting women with substance abuse and co-occurring mental health challenges. They offer a full spectrum of care, including intensive outpatient, extended residential stays, and standard outpatient services. Their treatment methodologies include 12-step facilitation, anger management, and brief intervention strategies. Notably, Alfre Inc provides specialized support for adult women who have experienced intimate partner violence, domestic abuse, and sexual assault. Serving adult women, seniors, and young adults, Alfre Inc is distinguished by its tailored approach and its unwavering dedication to fostering sustained recovery and overall well-being.

Aliviane Inc
El Paso, TX

Aliviane Inc, located in El Paso, TX, provides extensive addiction treatment services, specializing in intensive outpatient, outpatient, and medication-assisted treatment options including methadone, buprenorphine, and naltrexone. Utilizing scientifically proven methods such as anger management, cognitive behavioral therapy, and motivational interviewing, this establishment delivers customized support to adults, youth, and young adults regardless of gender. A key distinction of Aliviane Inc is its creation of unique treatment itineraries, guaranteeing customized assistance for every individual. With an unwavering dedication to superior care, Aliviane Inc is committed to guiding people toward a life free from addiction.

Aletheia House
Birmingham, AL

Aletheia House, situated in Birmingham, Alabama, delivers a wide range of substance abuse rehabilitation options, including intensive outpatient programs, outpatient services, and standard outpatient care. This center features targeted programs designed specifically for adult males, individuals who have faced trauma, and those living with HIV or AIDS. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational incentives, Aletheia House serves adults and young adults of every gender. The facility is committed to providing exceptional, personalized care, establishing itself as a crucial support system for individuals in need of effective addiction recovery services.

Aletheia House
Birmingham, AL

Aletheia House, situated in Birmingham, AL, delivers comprehensive substance abuse rehabilitation within a long-term residential environment, serving adult males exclusively. This facility provides tailored interventions for individuals managing HIV or AIDS, and those navigating the legal system. Employing proven therapeutic modalities such as anger management, cognitive behavioral therapy, and contingency management, the center customizes treatment plans for each resident. Catering to adult, senior, and young adult men, Aletheia House ensures round-the-clock residential care to foster enduring recovery.

Alcohol and Drug Dep Services of SE IA

Situated in Burlington, IA, the Alcohol and Drug Dep Services of SE IA presents a wide variety of treatment solutions for those struggling with substance use disorders. This center features intensive outpatient programs, extended residential care, and outpatient services. Employing evidence-based techniques such as cognitive behavioral therapy, motivational interviewing, and contingency management, the facility serves adolescents, adult males, adult females, along with older adults. With tailored programs for various age groups and genders, the center guarantees personalized attention. Clients can look forward to receiving quality support and care as they navigate their recovery journey, whether they need transitional housing, a halfway house, or a sober living environment.

Alcohol and Drug Freedom Center of

Situated in Mount Vernon, OH, the Alcohol and Drug Freedom Center delivers an extensive array of substance use disorder treatment for both adults and children facing simultaneous mental health challenges. The center offers various treatment modalities, including intensive outpatient, outpatient, and medications like methadone and buprenorphine. Employing a mix of strategies, such as cognitive behavioral therapy and community reinforcement with vouchers, it serves a diverse clientele, including adults, seniors, and specialized programs for teens, as well as men and women. With an emphasis on anger management and personalized care for each gender, this facility is dedicated to providing high-quality, customized support for individuals pursuing recovery from addiction.

Align Group Homes
San Tan Valley, AZ

Situated in San Tan Valley, AZ, Align Group Homes delivers comprehensive long-term residential treatment for substance use in a nurturing setting. The facility features transitional housing, halfway housing, and sober living arrangements for adult men and women. Programs specifically designed for active duty military members are also offered. Emphasizing 12-step methods, anger management, and brief intervention, this center serves both young and adult residents in need of effective care. With specialized offerings for each gender, Align Group Homes is committed to supporting individuals as they progress on the path to recovery.

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Alcohol and Drug Dep Services of SE IA, situated in Keokuk, IA, delivers extensive substance abuse care for adults and older adults. Their services include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside regular outpatient programs. They employ proven methods like cognitive behavioral therapy, motivational interviewing, and contingency management. Tailored services are available for adult men and women, recognizing gender-specific requirements. Prioritizing high-quality assistance, the center crafts personalized recovery strategies. For those needing effective addiction treatment, this establishment offers a nurturing setting for healing and rehabilitation.

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Alcohol and Drug Services (ADS) located in Greensboro, NC, provides a wide range of treatment options for adults dealing with substance use issues, as well as those who may have concurrent mental health challenges. The center’s offerings extend to address serious mental health concerns and emotional issues impacting children. ADS features intensive outpatient programs, standard outpatient care, and specialized services specifically for pregnant or postpartum women. The center employs methods such as 12-step facilitation and cognitive behavioral therapy to ensure personalized care based on evidence-based practices. With a solid focus on clients with dual diagnoses, ADS is committed to delivering customized support to meet each individual’s specific requirements. Catering to both adult men and women, along with young adults, this facility is devoted to offering exceptional and compassionate support for individuals embarking on their journey to recovery from addiction.

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Mandeville, LA

Situated in Mandeville, LA, the Alcohol and Drug Unit delivers exceptional treatment for substance use disorders aimed at both adults and young adults. Emphasizing the importance of co-occurring mental health conditions, this center offers targeted support for those with psychological challenges. Its programs feature anger management, cognitive behavioral therapy, and short-term intervention techniques. Designed for adult males and those involved with the criminal justice system, the center provides 24-hour residential care as well as short-term options to deliver thorough assistance. Demonstrating a dedication to high-quality treatment, this facility serves both men and women pursuing successful rehabilitation.

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Alcohol/Drug Care Services Inc, located in Eureka, CA, provides extensive addiction recovery services for both adults and young adults. Focused on detoxification, treatment for substance use disorders, and addressing co-occurring conditions, this center offers long-term residential support with round-the-clock assistance. Employing techniques like 12-step facilitation, anger management, and brief intervention, the facility customizes its care to meet the unique needs of each client. There are specialized programs designed for individuals who have experienced intimate partner violence, sexual abuse, and trauma. Committed to delivering high-quality care, Alcohol/Drug Care Services Inc accommodates male and female clients, offering tailored, gender-specific recovery support.

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Aldie Counseling Center, situated in Langhorne, PA, delivers comprehensive substance abuse treatment for individuals of all ages. Their offerings include intensive outpatient services, standard outpatient care, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center emphasizes therapeutic modalities such as anger management, brief interventions, and cognitive behavioral therapy, ensuring personalized treatment plans. They further distinguish themselves with specialized programs designed for adult men, adult women, and survivors of sexual abuse, allowing for highly focused support. Aldie Counseling Center is committed to providing effective and empathetic addiction recovery services to both male and female clients.

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Reidsville, NC

ALEF Behavioral Group, located in Reidsville, NC, delivers tailored outpatient addiction recovery services for adults and young adults. Their offerings include intensive outpatient care, standard outpatient services, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs strategies such as 12-step facilitation, anger management, and brief intervention, all customized to meet individual client requirements. ALEF Behavioral Group extends specialized care to pregnant and postpartum women, and maintains distinct programs for male and female clients to foster a supportive, gender-sensitive recovery atmosphere. Opt for ALEF Behavioral Group for reliable and impactful substance use disorder treatment.

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ALEF Behavioral Group Reidsville, located in Reidsville, NC, specializes in providing tailored treatment for substance use disorders for both adults and young adults. The facility features intensive outpatient programs, standard outpatient services, and options for methadone/buprenorphine or naltrexone treatment. Emphasizing 12-step support, anger management, and brief intervention techniques, the center serves clients of all genders. Additionally, it offers specialized programs for pregnant and postpartum women, ensuring holistic support for every individual. Committed to high-quality care and personalized treatment plans, this center is an essential resource for effective addiction recovery in the Reidsville region.

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Situated in Alexandria, VA, the Alexandria Community Services Board delivers extensive treatment options for substance use issues among both adults and children facing simultaneous mental health challenges. This center offers outpatient services such as anger management, cognitive behavioral therapy, and short-term interventions. It features tailored programs for teenagers, individuals with dual diagnoses, and those involved in the criminal justice system, accommodating a wide range of clients. The treatment modalities include outpatient alternatives like methadone, buprenorphine, or naltrexone. The Alexandria Community Services Board focuses on providing high-quality, evidence-driven care to support all genders in their journey towards recovery.

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Alhambra Valley Retreat LLC, located in Martinez, CA, provides extensive treatment for adult men struggling with substance use issues. This center is particularly focused on addressing co-existing substance use problems and significant mental health challenges among adults, alongside severe emotional issues in children. Offering both long-term and short-term residential options, as well as 24/7 care, the facility customizes its treatment strategies, incorporating methods like 12-step programs, anger management, and quick intervention techniques. Special initiatives are designed for adult men, as well as individuals affected by intimate partner violence, domestic violence, or sexual abuse. Catering to adults, seniors, and young adults, this center emphasizes high-quality, personalized care aimed at achieving sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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