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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Freedom Village
Sanborn, NY

Situated in Sanborn, NY, Freedom Village stands out as a leading rehabilitation facility focused on helping adult and senior men dealing with substance abuse issues. The center features long-term residential options and around-the-clock support, delivering personalized treatment plans that include 12-step programs, anger management techniques, and brief intervention strategies. Notably, it offers dedicated services for active military members and veterans, providing crucial assistance to those who have served. With a commitment to personalized care and a nurturing atmosphere, Freedom Village aims to empower clients toward sustainable recovery and enhanced well-being.

Freeman Recovery Center LLC

Freeman Recovery Center LLC, located in Dickson, TN, offers an extensive array of services for individuals dealing with substance use issues and provides transitional housing solutions. This center focuses on individuals who are grappling with both substance use disorders and significant mental health challenges in adults, as well as emotional issues in children. It features intensive outpatient programs and day treatment options, applying evidence-based methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy. Customized programs are designed for adult men and women, as well as those who have faced trauma. Committed to delivering personalized, high-quality care, Freeman Recovery Center LLC aims to support long-term recovery for all genders among adults and young adults.

Frontier Health
Kingsport, TN

Frontier Health, situated in Kingsport, TN, specializes in a wide range of rehabilitation services targeting substance use disorders alongside mental health issues for both adults and children. The center offers various levels of care, including intensive outpatient programs, standard outpatient services, and specific treatments using methadone, buprenorphine, or naltrexone. Emphasizing approaches such as 12-step programs, anger management, and short-term interventions, Frontier Health is designed for those who have faced trauma, individuals with dual diagnoses, and those in contact with the criminal justice system. The facility serves a diverse population of adults and young adults, ensuring that quality care and tailored treatment plans are at the forefront of their recovery efforts.

Freedom Institute Inc

Freedom Institute Inc located in New York, NY, provides focused treatment for substance use disorders in both adults and young adults who also face significant mental health challenges or emotional issues. Their customized services comprise intensive outpatient, outpatient, and standard outpatient programs. By employing research-supported methodologies such as motivational interviewing and strategies for preventing relapse, this center ensures high-quality, personalized care. With an emphasis on short-term interventions and a gender-sensitive approach for all individuals, Freedom Institute Inc is distinguished by its dedication to delivering individualized support for those on the journey to recovery from substance abuse and mental health difficulties.

Friends of Bridge Inc
Valley Stream, NY

Friends of Bridge Inc, situated in Valley Stream, NY, provides thorough outpatient services for detoxification and addressing substance use disorders. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies to foster healing. The center is equipped to support individuals across different age groups and genders, offering specialized programs for young people, adult men, and adult women. They deliver gender-specific care to both adult and adolescent populations. For those in search of reliable addiction recovery assistance within a nurturing atmosphere, Friends of Bridge Inc is committed to guiding individuals toward sustained abstinence and improved well-being.

Friend Health
Chicago, IL

Situated in Chicago, IL, Friend Health delivers focused outpatient services for adults dealing with substance use disorders alongside serious mental health challenges, as well as emotional issues in children. The center emphasizes anger management, cognitive behavioral therapy, and short-term interventions, offering personalized care for both men and women. Special programs are available for adolescents, women, and individuals who have suffered sexual abuse. With outpatient options including methadone/buprenorphine or naltrexone therapies, along with regular outpatient services, this center provides thorough support for both adults and children on their path to recovery. Friend Health is recognized for its exceptional care and varied treatment approaches.

Freedom Recovery LLC

Freedom Recovery LLC, located in Yelm, WA, delivers extensive addiction treatment services for adults and older adults. Their offerings include intensive outpatient, standard outpatient, and flexible outpatient plans, all customized to meet specific requirements. The center emphasizes 12-step engagement, emotional regulation techniques, and short-term intervention strategies, serving active military personnel, young people, and adult males. With distinct treatment tracks for men and women, Freedom Recovery LLC is committed to providing high-caliber support for individuals pursuing freedom from addiction. For those seeking impactful and individualized recovery solutions, this center is devoted to aiding your path to sustained well-being.

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Freedom House Recovery Center, located in Chapel Hill, NC, provides a wide array of detox services for both adults and young adults. The center offers various options, including inpatient detox in a hospital setting, residential detox, and 24-hour inpatient care. It specializes in techniques such as 12-step support, anger management, and brief intervention strategies, serving adult men and women facing simultaneous mental health and substance use challenges. Patients benefit from personalized care in a nurturing environment that fosters recovery and healing. Prioritizing empathetic and high-quality treatment, Freedom House Recovery Center is a reliable choice for individuals pursuing effective addiction rehabilitation.

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Freedom House Recovery Center, located in Roxboro, NC, specializes in treating adults who face substance use issues alongside significant mental health disorders. The center offers a range of treatment options, including intensive outpatient services, standard outpatient care, and medications such as methadone, buprenorphine, or naltrexone. Emphasizing de-escalation of anger, short-term interventions, and cognitive behavioral therapy, the center customizes its services to meet the unique needs of each client. There are dedicated programs for active duty military members as well as specific services for adult men and women. Freedom House Recovery Center is committed to providing exceptional, all-encompassing care for adults and seniors, regardless of gender, within a nurturing setting.

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Freedom House Recovery Center, located in Durham, NC, provides extensive long-term residential treatment for adult women facing substance use challenges. The center fosters a nurturing atmosphere with specialized services for individuals who have undergone intimate partner violence, domestic abuse, and sexual trauma. Employing methods like 12-step programming, brief interventions, and relapse prevention strategies, the focus remains on holistic healing. Designed for women across different age groups, including adults and seniors, the program guarantees customized care. With options for transitional housing and a sober living environment, Freedom House Recovery Center emphasizes high-quality care and tailored support to promote enduring sobriety and overall well-being.

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Freedom House Recovery Center, located in Chapel Hill, NC, specializes in long-term residential treatment for substance use disorders, specifically designed for adult males. This center serves as a refuge for individuals who have endured intimate partner violence, domestic violence, and sexual abuse. Its programs emphasize 12-step principles, anger management strategies, and brief intervention techniques, catering to a diverse clientele that includes adults, seniors, and young adults in need of focused support. With options for transitional housing, halfway houses, and sober living arrangements, the center fosters a nurturing atmosphere conducive to recovery. Dedicated to providing high-quality and personalized care, Freedom House Recovery Center is a symbol of hope for those embarking on their healing journey.

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Freedom House Recovery Center in Durham, NC, is dedicated to providing extensive support for adult men battling substance use disorders, offering both treatment and transitional housing. The center emphasizes long-term residential care, utilizing proven therapeutic approaches such as 12-step facilitation, brief interventions, and motivational incentives. This specialized facility is designed to meet the distinct challenges faced by adult men in recovery. Serving a broad age range from young adults to seniors, the 24-hour residential program ensures continuous care and encouragement. By maintaining a male-only environment, Freedom House Recovery Center fosters a secure and supportive atmosphere conducive to achieving lasting sobriety.

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Freedom House Recovery Center, located in Warrenton, NC, delivers complete care for adults dealing with substance abuse and coinciding mental health issues. The center features intensive outpatient, standard outpatient, and regular outpatient services, all customized to each person's specific requirements. Employing methods such as anger management, cognitive behavioral therapy, and brief intervention strategies, the facility guarantees care that is uniquely fitted to each individual. With dedicated programs for active military personnel, young people, and adult men, the center accommodates a wide array of individuals. Open to adults and older adults of any gender, this establishment emphasizes high-quality treatment and comprehensive wellness for those pursuing recovery from addiction and mental health concerns.

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Freedom House Recovery Center, located in Chapel Hill, NC, delivers tailored substance abuse rehabilitation for adults experiencing co-occurring severe mental health conditions and children with significant emotional disorders. This establishment features intensive outpatient services, day treatment, and partial hospitalization options, serving adults and elderly individuals of any gender. The center offers distinct programs for teenagers, adult males, and adult females, employing methods such as 12-step facilitation, anger management techniques, and brief intervention strategies to ensure superior and personalized support. Freedom House Recovery Center is committed to promoting enduring sobriety for individuals pursuing complete and gender-focused addiction recovery.

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Situated in Alpena, MI, Freedom Recovery Center specializes in outpatient programs for substance use treatment, assisting individuals in their recovery process. The facility offers targeted outpatient therapies including methadone, buprenorphine, and naltrexone, along with 12-step programs, anger management, and brief intervention services. Designed to accommodate various groups, the center has specific programs for active duty military, adult men, and women, as well as services for seniors and young adults. Freedom Recovery Center is committed to providing excellent care in a nurturing environment for those pursuing recovery. Treatment plans are customized for both male and female clients, focusing on their individual requirements.

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Freeman Recovery Center LLC, situated in Burns, TN, provides extensive addiction treatment solutions. Their offerings include extended residential stays, inpatient detoxification, and round-the-clock residential supervision. Utilizing approaches such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center serves adult men and women, as well as young adults. Specialized care is offered for adult men, adult women, and individuals with a history of trauma. Freeman Recovery Center LLC is committed to delivering excellent, tailored support for those pursuing lasting recovery.

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Fresh Start Treatment Facility located in Indianapolis, IN, provides a wide range of rehabilitation services designed for adults and young adults facing substance use challenges alongside mental health issues. The center offers various programs, including detoxification, intensive outpatient, long-term residential, and general outpatient treatment. Emphasizing 12-step support, anger management strategies, and brief therapeutic interventions, the facility is well-equipped to address the needs of those with histories of trauma, dual diagnoses, and pain management challenges. Catering to both men and women, Fresh Start Treatment Facility ensures that every client receives a customized recovery plan and exceptional care.

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Friend Family Health Center, located in Chicago, IL, provides a wide range of outpatient rehabilitation services tailored for individuals dealing with substance use issues alongside mental health challenges, applicable to both adults and children. Emphasizing personalized care, the center offers treatments including methadone, buprenorphine, and naltrexone therapies, as well as anger management, cognitive behavioral therapy, and targeted programs designed for adolescents, women, and survivors of sexual abuse. This facility caters to both men and women, ensuring quality care through short-term interventions that are customized to fulfill each person's distinct requirements. If you or someone close to you is in search of empathetic and effective rehabilitation options, explore the varied programs at Friend Family Health Center.

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Friend Family Health Center in Chicago, IL, delivers extensive outpatient care designed for individuals struggling with addiction and co-occurring mental health issues, serving adults and children with significant emotional difficulties. Emphasizing excellent service, they offer targeted support for teenagers, adult women, and survivors of sexual abuse. Patients can access customized outpatient plans utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. The center welcomes both men and women of all ages, promoting a complete path to healing for those requiring assistance with substance dependence and psychological well-being.

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Friend Family Health Center in Chicago, IL, delivers extensive outpatient care for adults grappling with substance use disorders alongside severe mental health conditions, and for children experiencing significant emotional challenges. This establishment features tailored services for teenagers, adult women, and individuals who have endured sexual trauma. Their therapeutic modalities encompass anger reduction, immediate support strategies, and cognitive behavioral interventions. The center serves both genders, providing outpatient options for methadone, buprenorphine, or naltrexone. Emphasizing excellent care and custom recovery strategies, Friend Family Health Center is committed to supporting each person's journey toward healing.

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Friend Family Health Center in Chicago, IL, provides extensive outpatient rehabilitation for those with substance use and co-occurring mental health issues. They offer tailored programs for adults with severe mental health conditions and children with emotional challenges. Employing diverse methods like anger management, cognitive behavioral therapy, and brief interventions, the center addresses individual client needs. Targeted support exists for adolescents, adult women, and survivors of sexual abuse. Serving all genders and ages, this center is committed to delivering excellent care and fostering recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)