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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Hunterdon Medical Center/Add Trt Servs

Hunterdon Medical Center/Add Trt Servs, situated in Flemington, NJ, delivers thorough care for adults navigating substance use disorders alongside serious mental health concerns. This center provides intensive outpatient, standard outpatient, and partial hospitalization programs, incorporating therapeutic strategies such as 12-step facilitation and anger management. Their expertise lies in assisting individuals with dual diagnoses, including older adults. The facility is equipped to serve both men and women. By prioritizing evidence-based practices and personalized recovery pathways, Hunterdon Medical Center/Add Trt Servs guarantees excellent rehabilitation services for adults and seniors striving for recovery from addiction and mental health issues.

Huntington Comprehensive Trt Ctr

Situated in Huntington, WV, the Huntington Comprehensive Trt Ctr delivers a variety of outpatient services designed for adults and young adults dealing with substance use issues alongside mental health challenges. The center focuses on detoxification, treatment for substance use, and support for individuals facing severe mental health conditions. Services include outpatient detox, as well as medication-assisted treatments using methadone, buprenorphine, and naltrexone. Their approach combines 12-step facilitation, anger management strategies, and brief intervention methods to aid recovery. With dedicated programs for adult men, adult women, and individuals with co-occurring disorders, the center prioritizes personalized care that addresses the specific requirements of each client.

Huntington Creek Recovery Center

Huntington Creek Recovery Center, situated in Shickshinny, PA, provides a wide array of services for individuals battling addiction. With a focus on both detoxification and treatment for substance use disorders, the center offers options such as residential detox, continuous care, and short-term programs. Utilizing effective methodologies like 12-step support, anger management strategies, and cognitive behavioral therapy, the facility serves a diverse clientele, including adults, teenagers, and military personnel. Customized programs designed for adult men, women, and youths ensure that each individual receives the care they need. Huntington Creek Recovery Center is recognized for its high-quality services and varied specialized offerings, making it an excellent option for those in search of tailored addiction recovery solutions.

INSynergy Treatment Program

The INSynergy Treatment Program located in Saint Louis, MO, offers an extensive variety of outpatient services aimed at detoxification, substance use recovery, and managing co-existing mental health issues in adults, alongside emotional challenges in children. This program features targeted outpatient detox services and options for methadone/buprenorphine treatment. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, the facility serves adult men and women, including those with dual diagnoses of mental health and substance use disorders. Committed to providing exceptional care in a nurturing and welcoming atmosphere, INSynergy Treatment Program supports individuals of all ages and genders, including adults, children, and teenagers.

IBH Addiction Recovery

Situated in Akron, Ohio, IBH Addiction Recovery delivers thorough care for substance use disorders and provides targeted interventions for individuals facing dual diagnoses of mental health conditions. They feature intensive outpatient, standard outpatient, and day treatment modalities, employing proven therapeutic techniques like 12-step support and emotional regulation strategies. Emphasizing a trauma-sensitive approach, IBH Addiction Recovery serves adults of all genders and young adults. Patients receive individualized care plans and high-quality support within a nurturing setting designed to meet their specific requirements.

ITRS Outpatient
Lansing, MI

ITRS Outpatient, located in Lansing, MI, delivers extensive rehabilitation services aimed at adults and children facing challenges related to substance use disorders and concurrent mental health issues. The center implements intensive outpatient programs that utilize proven methods such as cognitive behavioral therapy and motivational interviewing. ITRS Outpatient excels in addressing the needs of individuals with intricate circumstances, including those within the criminal justice system, offering personalized treatment plans. With specialized programs for both adults and youth, the facility is dedicated to providing exceptional, gender-sensitive care that fosters sustainable recovery and enhances overall health.

Human Development Center

The Human Development Center in Duluth, MN, delivers extensive addiction treatment for adults grappling with concurrent serious mental health conditions or developmental challenges in youth. This establishment features robust intensive outpatient and outpatient services, incorporating pharmacotherapy such as methadone, buprenorphine, or naltrexone. Emphasizing strategies like 12-step integration, motivational interviewing, and cognitive behavioral approaches, the center accommodates adult males and females, along with individuals facing dual diagnoses. Serving adults and older adolescents of all genders, this facility is dedicated to providing tailored care that meets distinct personal requirements, fostering effective recovery and comprehensive assistance.

IL Institute for Addiction Recovery

The IL Institute for Addiction Recovery, situated in Peoria, IL, provides extensive support for individuals battling addiction. Their specialized services include hospital-based inpatient detoxification and treatment for various substance use disorders. Employing evidence-based strategies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, they deliver tailored care to adult men and women. Distinctive programs are available for those who have faced intimate partner or domestic violence. This center also offers gender-specific treatment for both adult and young adult female and male patients. Committed to high-quality, individualized recovery plans, the IL Institute for Addiction Recovery is devoted to fostering long-term healing.

Human Service Center of

Situated in Rhinelander, WI, the Human Service Center offers an extensive range of outpatient rehabilitation services aimed at addressing substance use disorders alongside concurrent mental health issues. The center features targeted programs designed specifically for adult men, women, and young adults, ensuring that treatments are appropriate for different age demographics and genders. By employing evidence-based methods such as 12-step facilitation, cognitive behavioral therapy, and short interventions, the center guarantees personalized attention. It provides various treatment options, including outpatient, methadone/buprenorphine, or naltrexone therapies, along with regular outpatient services, all aimed at fostering holistic recovery for adults and seniors. Discover effective care and impactful treatment at the Human Service Center.

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Human Supports of Idaho Inc, located in Boise, ID, specializes in treating substance use disorders and addressing the needs of individuals who are faced with severe mental health challenges. The center provides a range of services, including intensive outpatient treatment and various outpatient programs, such as those involving methadone, buprenorphine, or naltrexone. Emphasizing methods like 12-step facilitation, anger management, and brief intervention, this facility is designed to meet the unique needs of adult men and women, particularly those affected by intimate partner violence. Catering to adults and seniors of all genders, Human Supports of Idaho Inc focuses on personalized care and employs evidence-based strategies to enhance recovery and overall health.

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Human Supports of Idaho Inc, located in Caldwell, ID, specializes in a wide range of rehabilitation services designed for adults and seniors grappling with substance use as well as co-occurring severe mental health disorders or emotional issues. The center offers both intensive outpatient and outpatient care options, incorporating treatments such as methadone/buprenorphine or naltrexone. It features targeted programs for adult men, adult women, and individuals who have faced intimate partner violence, addressing various client needs. By employing methods like 12-step facilitation, anger management, and brief interventions, the center provides personalized care for every individual. Committed to high-quality, customized support, Human Supports of Idaho Inc aims to empower individuals on their journey to sustainable recovery.

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Humboldt Recovery Center Inc, situated in Eureka, CA, delivers focused programs for substance use treatment within a peaceful residential atmosphere. The center offers various options including long-term, short-term, and round-the-clock residential care exclusively for adult males. Emphasizing the 12-step approach, anger management strategies, and cognitive behavioral therapy, the center customizes its programs to meet the unique needs of each client. Specialized services are available for adult men and those who have endured intimate partner violence or sexual trauma. Humboldt Recovery Center Inc is open to adults, seniors, and young adults who are looking for a nurturing environment conducive to recovery. Here, clients will find compassionate support and proven treatment methods aimed at fostering enduring sobriety.

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Situated in Eureka, California, Humboldt Recovery Center Inc provides dedicated treatment for adult males dealing with substance use issues in a nurturing and secure setting. The center features extensive long-term, 24-hour residential, and short-term residential care that integrates 12-step support, anger management strategies, and cognitive behavioral therapy. Humboldt Recovery Center Inc is particularly distinguished by its commitment to assisting those who have faced intimate partner violence, domestic abuse, and sexual trauma. With customized programs for adults, seniors, and young adults, this facility prioritizes personalized care and guidance for men striving to conquer addiction and establish a sustainable path to recovery.

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Situated in Eureka, California, Humboldt Recovery Center Inc specializes in providing tailored substance use therapies for adult males in a nurturing and secure setting. This center offers various treatment options, such as long-term, short-term, and round-the-clock residential programs. With an emphasis on 12-step support, anger management, and cognitive behavioral therapy, it specifically serves clients who have faced challenges related to intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, seniors, and young adults, Humboldt Recovery Center Inc prioritizes personalized care designed to meet the unique needs of each individual, focusing on effective treatment and support for sustainable recovery.

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Humboldt Recovery Center Inc, located in Eureka, CA, delivers tailored programs for substance use treatment in a nurturing setting. The facility offers a variety of treatment approaches, including long-term residential, 24-hour residential, and short-term residential options. It emphasizes evidence-based practices such as cognitive behavioral therapy, 12-step methodologies, and anger management techniques. The center features distinct programs designed specifically for adult males and individuals who have survived experiences of intimate partner violence or sexual assault. Catering to adults, seniors, and young adults, this center focuses primarily on services for men. With a strong dedication to high-quality care and personalized treatment plans, it serves as a crucial resource for individuals seeking thorough support in their recovery journey.

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Humboldt Recovery Center Inc, situated in Eureka, CA, provides a complete range of substance abuse rehabilitation services for adult women within a nurturing atmosphere. This establishment features extended stay residential, 24-hour residential, and brief residential treatment options. The center's expertise lies in its application of 12-step facilitation, anger control techniques, and cognitive behavioral therapy methodologies. Specialized services are available for adult women, individuals who have endured intimate partner violence, domestic abuse, and sexual trauma. Catering to a broad demographic including adults, seniors, and young adults, this center prioritizes personalized treatment plans and scientifically validated methods to foster enduring sobriety.

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Humboldt Recovery Center Inc, located in Eureka, CA, provides focused addiction treatment services for adult women within a nurturing setting. The center offers diverse treatment modalities, encompassing extended stay residential, round-the-clock residential, and brief residential programs. Emphasizing 12-step integration, emotional regulation techniques, and cognitive behavioral approaches, the facility personalizes treatment to address distinct requirements. Humboldt Recovery Center Inc distinguishes itself with unique offerings for adult women, particularly those with histories of domestic violence or sexual trauma. Catering to a broad age range from young adults to seniors, this institution is dedicated to delivering excellent care and extensive assistance to women on their path to recovery.

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Rochester, NY

Huther Doyle, situated in Rochester, NY, provides extensive outpatient care for individuals of all ages dealing with substance use, detoxification, and co-occurring mental health conditions. Their expertise includes outpatient detox, medication-assisted treatment (methadone/buprenorphine), and therapeutic interventions such as anger management and cognitive behavioral therapy. The center is dedicated to serving specific populations including adolescents, women, and those affected by trauma, ensuring tailored, high-quality support for everyone pursuing a life of recovery.

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Morocco, IN

IFC Clinics, located in Morocco, IN, provides an extensive array of services aimed at treating addiction for both adults and young individuals. The facility offers detox services and specialized treatment for substance use, with a focus on individuals facing dual challenges of substance use disorders and severe mental health issues in adults, as well as significant emotional disturbances in minors. Treatment options include intensive outpatient programs, outpatient care, and day treatment, allowing the center to customize its services based on individual requirements. Employing evidence-based methods such as 12-step programs, brief interventions, and cognitive behavioral therapy, IFC Clinics maintains a high standard of care. The center has specialized initiatives for adult men, adult women, and those dealing with concurrent mental health and substance use issues. IFC Clinics is open to male and female clients, providing assistance to a broad spectrum of individuals on their path to recovery.

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Lawrenceburg, IN

Situated in Lawrenceburg, IN, INcompass Healthcare specializes in treating adults and children dealing with substance use disorders alongside significant mental health challenges. The center offers various outpatient services, such as intensive outpatient programs and partial hospitalization, designed to meet diverse needs. INcompass Healthcare employs proven methods including 12-step facilitation, anger management, and brief interventions to aid individuals in their recovery process. With an emphasis on personalized treatment, the facility serves adults and seniors of all genders, crafting specific plans that cater to each client’s unique situation. Discover empathetic and all-encompassing support at INcompass Healthcare.

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Lawrenceburg, IN

INcompass Healthcare, located in Lawrenceburg, IN, provides tailored recovery programs for individuals grappling with addiction and associated mental health challenges, serving both adolescents and adults. Their approach encompasses a spectrum of care, from intensive inpatient hospital stays to sustained residential living, all designed with personalization at its core for men, women, and seniors. Employing proven therapeutic techniques like 12-step support, emotional regulation training, and concise counseling, INcompass Healthcare guarantees advanced treatment strategies adapted to the unique journey of each patient. For a supportive and successful path to healing, INcompass Healthcare is committed to delivering excellent services for enduring sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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