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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Journey Road Treatment Center

Journey Road Treatment Center, situated in Indianapolis, IN, delivers an extensive variety of outpatient support for those on the path to recovering from substance use issues and related mental health challenges. The center specializes in detox services, treatment for substance use, and targeted assistance for adults facing significant mental health disorders, as well as children grappling with serious emotional challenges. Utilizing effective methods like cognitive behavioral therapy and motivational strategies, the center serves a wide demographic, including adults, children, adolescents, men, and women. Additionally, there are customized programs specifically designed for active duty service members, adult males, and adult females, ensuring that care is personalized for various groups. Journey Road Treatment Center emphasizes high-quality, evidence-based care to aid individuals in achieving lasting sobriety and improving their mental health.

JourneyPure
Bowling Green, KY

Situated in Bowling Green, KY, JourneyPure provides a wide range of treatment alternatives for those looking to recover from substance use issues and related mental health challenges. The center features various levels of care, including intensive outpatient programs, outpatient day treatment, and partial hospitalization, all founded on evidence-based methods like 12-step facilitation, cognitive behavioral therapy, and brief interventions. JourneyPure offers tailored programs designed for active duty military members as well as adult men and women, addressing a variety of needs. This facility is committed to serving adults and young adults of all genders, emphasizing personalized care and fostering a nurturing atmosphere to promote enduring recovery experiences.

JourneyPure
Lexington, KY

Situated in Lexington, KY, JourneyPure provides an extensive variety of treatment services for substance use disorders aimed at both adults and young adults. The facility focuses on addressing dual diagnoses, managing both substance use issues and serious mental health conditions in adults, as well as emotional challenges in children. Treatment modalities offered include intensive outpatient programs, regular outpatient services, and day treatment. JourneyPure employs a therapeutic strategy that features 12-step support, brief interventions, and cognitive behavioral therapy techniques. The center also has specialized programs designed for active duty military members and distinct services for adult men and women, ensuring personalized care for different groups. Clients can anticipate high-quality support in a nurturing environment that emphasizes recovery and overall wellness.

JourneyPure
Murfreesboro, TN

JourneyPure in Murfreesboro, TN, delivers extensive addiction recovery support. This center features hospital-level inpatient detox and treatment, with continuous medical supervision. Key therapeutic methods include 12-step program integration, emotional regulation strategies, and short-term counseling. JourneyPure serves active military, adult males, adult females, and provides services for both adults and younger adults. Emphasizing patient well-being, the center crafts personalized recovery paths. From initial detox to supportive sober living, JourneyPure is committed to guiding individuals toward sustained sobriety.

JourneyPure
Louisville, KY

JourneyPure, situated in Louisville, KY, delivers extensive addiction recovery services for adults and adolescents. This institution is particularly adept at addressing dual diagnoses of substance abuse and severe mental health conditions in adults, alongside significant emotional challenges in children. Their treatment offerings include intensive outpatient, outpatient, and partial hospitalization programs. Emphasizing 12-step facilitation, brief intervention, and cognitive behavioral therapy, JourneyPure customizes recovery plans to suit each person's unique requirements. Specialized tracks are available for active duty military members, as well as adult men and women. This center is committed to providing excellent care for all clients, fostering a nurturing atmosphere conducive to healing and sobriety.

JourneyPure Bowling Green
Elizabethtown, KY

Situated in Elizabethtown, KY, JourneyPure Bowling Green delivers a variety of research-backed therapies aimed at addressing substance use disorders and related mental health issues in both adults and children. The center features intensive outpatient programs, standard outpatient care, and day treatment options that utilize methods such as 12-step principles, cognitive behavioral therapy, and brief interventions. Tailored programs are available for active duty military members, as well as adult males and females. This facility is dedicated to providing personalized care and assistance for individuals of all genders throughout their recovery process, focusing on high-quality treatment and empathetic support for those pursuing meaningful transformation.

Journeys in Mental Health and Wellness

Journeys in Mental Health and Wellness in Wendell, NC, provides focused outpatient care for adults and children dealing with addiction and simultaneous mental health issues. The clinic offers various treatment options, such as outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Their therapeutic methods incorporate anger management, brief intervention strategies, and cognitive behavioral therapy. Specifically designed programs are available for active military members, adult men, and adult women, demonstrating their commitment to serving a wide array of individuals. Accepting adults and young people of any gender, Journeys in Mental Health and Wellness is committed to delivering excellent support and care for those pursuing recovery from mental health and substance use challenges.

Jovive Health
Chicago, IL

Situated in Chicago, IL, Jovive Health specializes in outpatient treatment for adults and seniors dealing with substance use disorders. The facility employs a brief intervention strategy designed to meet the unique requirements of each individual. Jovive Health fosters an inclusive atmosphere for both male and female clients, promoting a nurturing environment throughout the recovery process. By prioritizing personalized attention and high-quality care, this center excels in delivering extensive addiction treatment services aimed at guiding clients toward sustainable recovery. For those seeking effective substance use treatment in Chicago, Jovive Health is here to assist you on your path to wellness.

Kaiser Permanente

Kaiser Permanente, situated in Fresno, CA, delivers a wide range of rehabilitation services for both adults and children dealing with substance use issues and associated mental health disorders. The center features several treatment formats, including intensive outpatient therapy, standard outpatient services, and day therapy. By employing proven techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the facility customizes its treatment plans to meet the unique needs of each individual. Kaiser Permanente is particularly adept at working with adolescents but also extends its services to adults and seniors of all genders. With a dedication to high-quality care and individualized support, this center has established itself as a reliable option for those in need of compassionate help in overcoming addiction.

Journey Treatment Center
Salt Lake City, UT

Journey Treatment Center, situated in Salt Lake City, UT, delivers a wide array of addiction recovery services designed for both adults and young adults. The center specializes in detoxification, treatment for substance use disorders, and targeted support for those dealing with co-occurring mental health issues. They offer various treatment modalities, including intensive outpatient care, long-term residential stays, and outpatient options. Employing methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, Journey Treatment Center focuses on individualized care. The facility also features specific programs for active duty military members, as well as separate offerings for adult men and women, addressing the unique requirements of each group. Both male and female clients are welcomed, with a strong commitment to high-quality care and customized treatment strategies.

JourneyPure
Panama City Beach, FL

Situated in Panama City Beach, FL, JourneyPure specializes in all-encompassing addiction rehabilitation for both adults and young adults. This center offers hospital-based detoxification services alongside treatment for substance use disorders and accompanying mental health issues. With dedicated programs for active duty military personnel, veterans, and their families, JourneyPure emphasizes a customized care strategy. The facility employs methods such as 12-step facilitation, anger management, and brief intervention to create individualized treatment plans. Catering to both men and women, JourneyPure is committed to delivering exceptional care and assistance throughout the recovery journey.

JourneyPure
Panama City Beach, FL

JourneyPure, situated in Panama City Beach, FL, delivers extensive services for the treatment of addiction, targeting both adults and young adults. The center features inpatient detoxification alongside treatment services and offers transitional housing solutions. Emphasizing 12-step facilitation, anger management, and brief interventions, JourneyPure customizes its programs to align with the unique requirements of each client. The facility is equipped to support active duty military members, as well as adult men and women. With specialized offerings and a focus on gender-specific care, JourneyPure is committed to providing exceptional support for individuals pursuing recovery from substance use issues.

Juneau Behavioral Health

Situated in Juneau, Alaska, Juneau Behavioral Health delivers extensive treatment options for substance use disorders in both adults and children, particularly for those facing simultaneous mental health challenges. The center features intensive outpatient and regular outpatient programs, offering tailored treatment with medications like methadone, buprenorphine, and naltrexone. Emphasizing 12-step support, anger management strategies, and brief intervention techniques, the facility serves clients of all genders. Additionally, specific programs are designed for individuals in the criminal justice system as well as those with co-occurring disorders. Juneau Behavioral Health is committed to offering exceptional care and assistance for individuals on their path to recovery.

Kaiser Permanente

Kaiser Permanente, situated in Oakland, CA, delivers a wide range of addiction treatment services catering to both adults and children. The facility specializes in detoxification, treatment for substance use, and management of concurrent mental health issues. Available treatment modalities include intensive outpatient programs, outpatient services, and day therapy options. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, the center customizes care to meet the specific requirements of each client. Kaiser Permanente also offers support programs designed for adolescents, LGBTQ individuals, and those dealing with co-occurring disorders, highlighting its dedication to inclusive and effective treatment solutions. The center accommodates clients of all genders, reinforcing its commitment to high-quality and varied care options.

Journey to Wellness Inc

Journey to Wellness Inc, situated in Perth Amboy, NJ, delivers extensive care for individuals struggling with substance abuse, serving both adults and younger adults. This establishment focuses on addressing dual diagnoses, managing co-occurring substance use and severe mental health conditions in adults, as well as serious emotional disturbances in children. Through various treatment approaches like intensive outpatient, outpatient, and day treatment, the facility offers services including 12-step support, anger control, and short-term counseling. Specialized programs are also provided for active military members, adult men, and adult women. Journey to Wellness Inc is dedicated to providing superior treatment for those on the path to recovery, accommodating both male and female patients.

Journeys Mental Health and Wellness

Journeys Mental Health and Wellness in Wilson, NC, provides comprehensive outpatient services designed to address substance use disorders, co-occurring mental health conditions, and childhood emotional challenges. The center features specialized therapeutic interventions including anger management, cognitive behavioral therapy, and brief intervention strategies. They offer distinct treatment tracks for active-duty military members, adult men, and women. Serving a diverse clientele across age groups and genders, from children to adolescents and adults, Journeys Mental Health and Wellness is committed to delivering personalized care and fostering lasting recovery through effective, holistic approaches.

Jude House Inc
Bel Alton, MD

Jude House Inc, located in Bel Alton, MD, provides extended residential care for adults and young adults dealing with substance abuse and co-occurring disorders. The center emphasizes 12-step programs, anger management techniques, and cognitive behavioral therapy, delivering focused support to both men and women, including those who have undergone traumatic experiences. Their offerings are designed for individuals suffering from significant mental health challenges or emotional issues. Jude House Inc fosters a nurturing atmosphere for all clients pursuing extensive rehabilitation options. For those in need of personalized treatment strategies and exceptional care, this facility is committed to guiding individuals toward their recovery journey.

Judicial Supervision Services LLC

Judicial Supervision Services LLC, located in Salt Lake City, UT, provides targeted programs for adults confronting dual diagnoses of substance use disorders and significant mental health challenges. Their treatment options include intensive outpatient, standard outpatient, and medication-assisted treatments such as methadone, buprenorphine, or naltrexone. The center employs therapeutic modalities like 12-step facilitation, anger management, and brief interventions. They extend services to active military personnel, adult men, and women. Judicial Supervision Services LLC supports adults and young adults of all genders, offering a comprehensive and supportive rehabilitation experience.

KOLPIA Counseling Services Inc

Situated in Ashland, OR, KOLPIA Counseling Services Inc delivers extensive treatment for adults dealing with substance use challenges alongside severe mental health disorders. The facility offers various programs, including intensive outpatient services, standard outpatient care, and outpatient treatments involving methadone, buprenorphine, or naltrexone. With an emphasis on cognitive behavioral therapy, strategies for relapse prevention, and counseling for substance use disorders, the center serves both adults and youth, including tailored programs for adolescents and specific services for adult men and women. By prioritizing personalized care and evidence-supported methods, KOLPIA Counseling Services Inc guarantees effective treatment for all clients pursuing recovery.

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Judicial Supervision Services LLC, located in Orem, UT, provides extensive treatment options for those struggling with substance use and co-existing serious mental health issues. The center features intensive outpatient programs alongside outpatient services, incorporating treatments like methadone, buprenorphine, and naltrexone. Emphasizing methodologies such as 12-step facilitation, anger management, and brief interventions, this facility supports active military members as well as men and women of adult and young adult ages. By offering personalized programs, the center is dedicated to delivering high-quality care that addresses each client's specific requirements.

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Judicial Supervision Services LLC in Clearfield, UT, is dedicated to providing effective care for individuals grappling with substance use issues and concurrent mental health challenges, serving both younger and adult populations. The program includes various levels of support, such as intensive outpatient, standard outpatient, and medication-assisted treatment involving methadone, buprenorphine, or naltrexone. Emphasis is placed on proven strategies like 12-step program integration, emotional regulation techniques, and concise, impactful interventions. This center is particularly equipped to assist active service members, adult men, and women, as well as young adults and adults of all gender identities. Judicial Supervision Services LLC commits to delivering high-quality, individualized addiction recovery services. If you are looking for thorough addiction treatment with a customized plan, this center is committed to aiding your path to wellness.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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