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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Keystone Recovery Center Inc

Keystone Recovery Center Inc, located in Little Falls, NJ, provides targeted treatment for substance use disorders in both adults and young adults. The center features a variety of programs, including intensive outpatient care, outpatient services, and daytime treatment options, which encompass partial hospitalization. Their treatment strategy incorporates methods such as 12-step programs, anger management, and brief intervention practices. Keystone Recovery Center Inc serves both men and women, including individuals who have faced sexual abuse. With an emphasis on personalized treatment, the facility delivers a range of comprehensive services designed to address the distinct needs of every client, ensuring effective support and quality care for those on their journey to recovery from addiction.

Kimberly ReGenesis Center

Experience renewal and recovery at the Kimberly ReGenesis Center located in Fort Myers, FL. This center provides tailored therapeutic programs for detox, substance abuse, and dual diagnosis issues affecting both adults and children. Emphasizing personalized treatment, the facility offers intensive outpatient as well as outpatient care, which includes detox services. Employing methods like 12-step support, anger control, and short-term intervention, the center serves a diverse clientele, including adult men and women, as well as young adults. Benefit from holistic support in an encouraging setting that fosters enduring health and rehabilitation.

Kindred Treatment Center

Kindred Treatment Center, located in Manchester, MD, delivers thorough addiction recovery services and expert support for individuals with dual diagnoses, encompassing mental health issues in adults and emotional challenges in youth. The center features intensive outpatient care, including medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like 12-step integration, anger management, and brief counseling, Kindred Treatment Center addresses each client's unique circumstances. Special programs are available for those navigating trauma, co-occurring mental health and addiction disorders, and pain management. Serving children and adolescents of all genders, Kindred Treatment Center is dedicated to providing excellent care and assistance to all on their path to healing.

Kings County Hospital Center

Kings County Hospital Center, situated in Brooklyn, NY, provides an extensive array of outpatient services aimed at detoxification, treatment for substance use, and addressing co-occurring disorders among adults and children. The center features outpatient detox options, along with methadone and buprenorphine therapies, and employs a variety of evidence-based techniques such as cognitive behavioral therapy and motivational interviewing. Programs are specifically designed for active military members, as well as for adult men and women. With a commitment to high-quality care and specialized offerings, Kings County Hospital Center is recognized as a leading option for those pursuing tailored addiction treatment solutions.

Kingsway Recovery LLC
Mullica Hill, NJ

Kingsway Recovery LLC, located in Mullica Hill, NJ, offers robust outpatient and intensive outpatient care for adults grappling with substance use disorders and associated mental health challenges. They cater to distinct programs for adult men and women, and individuals who have experienced trauma, employing methodologies like 12-step facilitation, anger management, and brief intervention. Their services are designed for adults and young adults across the gender spectrum, providing personalized support. Kingsway Recovery LLC distinguishes itself through its all-encompassing treatment strategies and patient-centered approach, positioning it as a leading provider of impactful and empathetic addiction recovery services in the Mullica Hill region.

Kinnic Falls
River Falls, WI

Situated in River Falls, WI, Kinnic Falls stands out as a leading rehabilitation facility dedicated to long-term residential care for adult males struggling with substance use disorders. The center focuses on addressing both substance-related issues and significant mental health challenges that may co-occur. Kinnic Falls fosters a nurturing atmosphere for individuals living with HIV or AIDS and employs diverse treatment methodologies, including 12-step programs and anger management strategies. With options for transitional housing, this facility serves a wide range of clients, from young adults to seniors. Renowned for its exceptional care and tailored treatment plans, Kinnic Falls is a preferred destination for those in pursuit of thorough and efficient addiction recovery solutions.

Kirkbride Center
Philadelphia, PA

Situated in Philadelphia, PA, the Kirkbride Center provides an extensive array of services aimed at helping adults and young adults with addiction issues. This center features long-term residential options, outpatient care, and outpatient programs incorporating methadone, buprenorphine, or naltrexone treatment. The Kirkbride Center is adept at addressing both co-occurring substance use disorders and significant mental health challenges in adults, in addition to serious emotional issues in children. Emphasizing 12-step support, anger management, and brief intervention techniques, the facility serves a diverse clientele, including specialized offerings for adult men, women, and individuals with a history of trauma. Recognized for its quality of care and individualized treatment strategies, the Kirkbride Center is a reliable choice for those pursuing recovery from addiction.

Knox County Community Health Center

The Knox County Community Health Center, situated in Mount Vernon, OH, delivers personalized outpatient care for substance use disorders. Their offerings include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Therapies like anger management, brief intervention, and cognitive behavioral therapy are utilized. The center serves adults and seniors across all gender identities, with specific programs for active military, teenagers, and adult men. The emphasis is on high-quality, customized support for lasting recovery and enhanced wellness.

Knox County Hospital
Washington, IN

Situated in Washington, IN, Knox County Hospital specializes in rehabilitative services aimed at addressing substance use disorders alongside co-occurring mental health issues for both children and adults. The facility offers a range of programs, including intensive outpatient options and standard outpatient services, featuring treatments such as methadone/buprenorphine and naltrexone. Utilizing a variety of methodologies like 12-step facilitation, anger management techniques, and brief interventions, the center customizes its approach to meet the unique needs of each individual. With specific programs designed for adult males and females, as well as inclusive services for seniors and all adult genders, Knox County Hospital is committed to delivering exceptional, personalized care to aid individuals on their path to healing.

Khepera House
Ventura, CA

Khepera House, situated in Ventura, California, stands as a leading facility providing inpatient hospital detoxification and comprehensive treatment services exclusively for adult men. This center distinguishes itself through its expertise in 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Khepera House delivers exceptional care, specifically designed to meet the unique requirements of LGBTQ individuals, forensic clients, and adult men. The facility's core mission is substance use disorder treatment, serving adults, seniors, and young adults who are looking for a nurturing environment to begin their recovery journey. At this respected institution, individuals can expect thorough and empathetic treatment aimed at conquering addiction.

Kite Clinic
Lafayette, LA

Kite Clinic in Lafayette, LA provides outpatient care for adults and young adults struggling with substance use, particularly those with co-occurring mental health conditions. Their approach emphasizes personalized treatment, utilizing methods such as brief intervention and motivational interviewing. Medication-assisted treatment options including methadone, buprenorphine, or naltrexone are available, alongside comprehensive relapse prevention strategies. Kite Clinic is committed to delivering individualized, gender-inclusive care that addresses the complex needs of individuals with both addiction and serious mental health concerns, offering a dedicated path to recovery.

Keystone Substance Abuse Services

Keystone Substance Abuse Services, located in Rock Hill, SC, provides a wide range of addiction recovery services tailored for both adults and teenagers. Their offerings encompass hospital-based detoxification, intensive outpatient programs, and around-the-clock inpatient support. The center is well-versed in various therapeutic methods, including 12-step programs, brief intervention strategies, and cognitive behavioral therapy. Keystone Substance Abuse Services features specialized care for adolescents, as well as distinct programs for adult men and women, ensuring that treatment is customized to meet individual needs. With provisions for both genders, this center fosters a welcoming and supportive atmosphere for all clients. Experience effective care and proven recovery solutions at Keystone Substance Abuse Services.

Kingsboro Addiction Treatment Center

Kingsboro Addiction Treatment Center, situated in Brooklyn, NY, provides tailored detox for adult men. Their approach incorporates 12-step facilitation, cognitive behavioral therapy, and motivational interviewing within a residential care model. This center is equipped to support seniors and older adults, developing personalized recovery strategies for all residents. Catering to a broad age range including adults, seniors, and young adults, Kingsboro Addiction Treatment Center emphasizes high-quality, gender-specific treatment designed for sustained sobriety. For those in search of committed addiction recovery services in a nurturing atmosphere, this facility is devoted to offering effective and empathetic support.

Kingsboro ATC
Brooklyn, NY

Kingsboro ATC, situated in Brooklyn, NY, delivers exceptional inpatient care for individuals battling substance use disorders. Employing evidence-based approaches like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this center offers personalized treatment for adult men and women, and young adults, particularly those with a history of trauma. The facility's tailored programs address the distinct challenges faced by each patient, providing robust assistance on their path to recovery. Kingsboro ATC is dedicated to providing superior, customized care, solidifying its reputation as a reliable provider of impactful and empathetic addiction treatment.

Kodiak Community Health Center

Situated in Kodiak, AK, Kodiak Community Health Center specializes in outpatient treatment for substance use disorders in both adults and children grappling with significant mental health challenges. The center offers a variety of outpatient options, including methadone/buprenorphine and naltrexone therapies, alongside standard outpatient services. Techniques such as cognitive behavioral therapy, anger management, and brief intervention are employed to enhance treatment outcomes. With an emphasis on personalized care, the center serves adults and seniors across all genders. Its dedication to high-quality care and tailored programs positions it as an essential resource for individuals in the Kodiak region seeking thorough and effective rehabilitation support.

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Key Recovery Outpatient Services located in Brookhaven, PA, provides targeted treatment for substance use issues through a variety of programs including intensive outpatient, outpatient, and options with methadone, buprenorphine, or naltrexone. The center employs techniques such as motivational interviewing, relapse prevention strategies, and counseling specifically for substance use disorders, catering to both adults and teens struggling with addiction. Key Recovery Outpatient Services places special emphasis on individuals facing trauma and those with concurrent mental health challenges, offering a well-rounded support system for every gender. Their dedication to high-quality, personalized care positions them as an excellent option for those in need of effective and empathetic rehabilitation solutions.

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At the Kinston Community Behav Health Ctr in Kinston, NC, adults and children facing co-occurring serious mental health issues can access outpatient substance use treatment. The facility features dedicated programs for individuals involved with the criminal justice system, emphasizing 12-step facilitation, anger management strategies, and brief intervention techniques. Designed to support both male and female patients, this center also provides outpatient services including methadone/buprenorphine or naltrexone treatment, alongside standard outpatient care. The Kinston Community Behav Health Ctr is dedicated to delivering high-quality rehabilitation services for young people and adults alike.

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Anadarko, OK

Situated in Anadarko, OK, Kiowa Alcohol Drug delivers thorough rehabilitation services for both adults and young adults dealing with substance use issues. This center is particularly adept at addressing co-occurring disorders related to substance use alongside severe mental health challenges in adults, and significant emotional issues in children. Kiowa Alcohol Drug offers various treatment options including intensive outpatient, outpatient, and standard outpatient programs. Employing methods such as 12-step facilitation, anger management, and brief intervention techniques, the center supports male and female clients, including those with trauma backgrounds. With an emphasis on personalized treatment plans, this facility is dedicated to providing effective recovery solutions for individuals struggling with addiction.

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Port Orchard, WA

Situated in Port Orchard, WA, Kitsap Recovery Center delivers a wide array of addiction rehabilitation services. This establishment encompasses various treatment methods, including detox and residential substance use care. The program implements proven strategies, such as cognitive behavioral therapy and motivational interviewing, to aid recovery. Kitsap Recovery Center serves both male and female adults as well as clients involved with the criminal justice system. Emphasizing 12-step support, the center aims to provide exceptional care for adults and young adults across all genders. For individuals in search of reliable and compassionate addiction treatment, Kitsap Recovery Center stands out as a respected option in the Port Orchard community.

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Klawock Behavioral Health, situated in Klawock, Alaska, delivers extensive outpatient services for individuals of all ages struggling with substance use disorders, particularly those facing co-occurring mental health challenges. Their expertise includes facilitating 12-step programs, managing anger, and employing brief intervention strategies, all while catering to those involved with the criminal justice system. The center offers distinct programs for men and women, incorporating medication-assisted treatment options like methadone, buprenorphine, or naltrexone, ensuring a personalized recovery journey. For those needing robust support for both addiction and significant mental health issues, Klawock Behavioral Health is committed to delivering high-quality, personalized care to support your healing process.

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Jasper, AL

Situated in Jasper, AL, Kolbe Clinic specializes in outpatient detox services and treatment for substance use disorders, as well as offering targeted support for adults dealing with co-occurring mental health issues or children facing emotional challenges. The center emphasizes a 12-step approach, anger management, and short-term interventions, delivering customized programs for both adults and young adults regardless of gender. Prioritizing high-quality care, Kolbe Clinic is noted for its outpatient treatments involving methadone and buprenorphine, along with its dedication to personalized treatment strategies. If you are in search of understanding and effective support for addiction recovery, this facility's individualized methodology may be ideal for your healing process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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