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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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La Fuente Hollywood Treatment Ctr LLC

La Fuente Hollywood Treatment Ctr LLC in Los Angeles, California, provides extensive care for individuals struggling with addiction. Their offerings include detox services, comprehensive substance use disorder treatment, and secure transitional and sober living environments for adults. The center supports adults and young adults through various treatment modalities, such as intensive outpatient, extended residential stays, and standard outpatient care. They also have specialized support for active-duty military members. La Fuente Hollywood Treatment Ctr LLC employs proven therapeutic methods, including 12-step facilitation, anger management techniques, and brief intervention strategies, ensuring personalized and effective recovery plans.

La Hacienda Treatment Center

Situated in Hunt, TX, La Hacienda Treatment Center delivers extensive addiction recovery programs for both adults and young individuals. This facility features hospital-level inpatient detox and treatment, focusing on co-existing substance use disorders alongside severe mental health issues in adults, and addressing significant emotional challenges in children. La Hacienda Treatment Center employs evidence-supported methodologies like 12-step facilitation, cognitive behavioral therapy, and strategies for preventing relapse. With programs designed specifically for adult men, adult women, and those who have faced trauma, this center guarantees personalized attention for every patient. By prioritizing gender-specific care for males and females alike, La Hacienda Treatment Center is committed to offering superior and effective rehabilitation solutions.

La Jolla Recovery
La Jolla, CA

Situated in La Jolla, CA, La Jolla Recovery delivers dedicated treatment for adults and seniors dealing with substance use issues. The facility features a variety of services, including intensive outpatient programs, standard outpatient care, and partial hospitalization options. With an emphasis on 12-step methods, anger management, and brief intervention strategies, this center serves both men and women, including those who have faced trauma. La Jolla Recovery prioritizes personalized care for its clients, focusing on high-quality treatment in a nurturing setting for individuals pursuing thorough addiction recovery.

La Jolla Recovery
La Jolla, CA

Situated in La Jolla, California, La Jolla Recovery stands out as a leading rehabilitation facility dedicated to assisting those facing challenges with substance use and related mental health issues. This center provides an array of services, including long-term residential treatment options, detoxification programs, and round-the-clock support for both adults and seniors. La Jolla Recovery emphasizes personalized care through methods such as 12-step guidance, anger management, and brief intervention techniques. Catering to adult men, adult women, and those with co-occurring conditions, this center is committed to fostering a nurturing recovery atmosphere. Whether you are in need of detox or extended therapeutic support, the facility is focused on providing exceptional care for individuals on their path to sustained recovery.

La Jolla Recovery
San Diego, CA

La Jolla Recovery, situated in San Diego, CA, provides extensive programs for addiction recovery and detox within a nurturing setting. The center features extended residential stays, immediate detoxification services, and constant residential support. Employing methods like 12-step guidance, emotional regulation techniques, and focused interventions, this establishment assists adult men and women, including those who have faced traumatic experiences. Catering to adults and older adults of all genders, La Jolla Recovery is committed to personalized treatment plans and tailored programs to guide each person through their recovery journey.

LGBT Community Center

Situated in New York, NY, the LGBT Community Center delivers outpatient services for substance use issues specifically aimed at adults within the LGBTQ community. The center offers tailored programs for individuals identifying as lesbian, gay, bisexual, transgender, or queer/questioning. Various therapeutic methods such as brief intervention, cognitive behavioral therapy, and the Matrix Model are employed, allowing for individualized treatment. The facility provides outpatient options for methadone/buprenorphine or naltrexone, assisting both male and female clients on their path to recovery. Discover understanding and efficient support at this prominent rehabilitation center created to address the distinct requirements of the LGBTQ population.

LRADAC
Columbia, SC

LRADAC in Columbia, SC, is dedicated to providing extensive addiction recovery solutions for adults and older individuals. They offer inpatient hospital detoxification, continuous hospital inpatient support, and structured outpatient therapy. Their services are designed to address both substance use disorders and co-occurring severe mental health conditions. Focusing on techniques such as anger management, brief intervention strategies, and cognitive behavioral approaches, LRADAC supports adolescents and adults of all genders. Their gender-informed programs offer customized care pathways for men and women. At LRADAC, individuals receive attentive treatment shaped around their specific recovery journeys.

LSA Recovery
Brooklyn, NY

LSA Recovery, located in Brooklyn, NY, provides outpatient treatment programs specifically designed for both adults and adolescents dealing with substance use challenges. This center caters to the unique needs of adult males, adult females, and younger populations, ensuring specialized support. Employing various treatment methodologies, such as 12-step programs, anger management techniques, and short intervention strategies, LSA Recovery emphasizes a holistic approach to recovery. The facility is particularly recognized for offering outpatient treatments using methadone/buprenorphine and naltrexone, delivering thorough care for those in need. LSA Recovery's commitment to high-quality, personalized care positions it as a leading option for individuals searching for effective and empathetic addiction therapy services in the Brooklyn area.

LSA Recovery Inc
Brooklyn, NY

LSA Recovery Inc, located in Brooklyn, NY, provides comprehensive outpatient care for individuals struggling with substance use disorders. Their offerings include medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs evidence-based therapeutic modalities such as 12-step facilitation, anger management techniques, and brief intervention strategies within its regular outpatient services. LSA Recovery Inc caters to a diverse clientele, with specialized programs for adolescents, adult men, and adult women, ensuring personalized support for adults and young people of all gender identities. The facility is committed to delivering high-quality, individualized treatment plans to foster sustained recovery from addiction.

LSA Recovery Inc
Brooklyn, NY

LSA Recovery Inc in Brooklyn, NY, offers extensive care for substance use disorders via several outpatient modalities, such as methadone/buprenorphine or naltrexone services and standard outpatient care. This center features dedicated tracks for young people, adult men, and adult women. Employing strategies like 12-step facilitation, anger management, and brief intervention, LSA Recovery Inc assists individuals of all ages and genders, including children and adolescents. Clients receive personalized attention and assistance from skilled practitioners, guaranteeing exceptional treatment for addiction recovery.

LSS Health Center
Columbus, OH

Situated in Columbus, OH, the LSS Health Center provides outpatient services for individuals dealing with substance use disorders, targeting both adults and young adults. This center has expertise in handling co-occurring substance use and significant mental health challenges in adults, along with emotional disturbances in children. The treatment methods incorporate proven techniques like cognitive behavioral therapy and contingency management. Emphasizing personalized care, the center offers ongoing outpatient therapy, including options for outpatient methadone/buprenorphine or naltrexone treatment. LSS Health Center serves a diverse clientele, ensuring a thorough and inclusive strategy for recovery from addiction.

LRADAC
Lexington, SC

LRADAC, located in Lexington, SC, provides extensive treatment for substance use disorders and specialized services for adults facing co-occurring mental health challenges and children dealing with serious emotional disturbances. The center features a range of treatment options, including intensive outpatient programs, outpatient services, and medications like methadone, buprenorphine, or naltrexone. They employ customized strategies such as anger management, brief interventions, and cognitive behavioral therapy. Additionally, there are specific programs designed for adolescents, as well as men and women, to address varying needs. LRADAC is dedicated to offering high-quality care and assistance to individuals of all genders, including seniors, throughout their recovery process.

La Frontera Center

La Frontera Center, situated in Tucson, Arizona, delivers thorough addiction recovery services for adults and young adults. Their offerings include outpatient care, with options for methadone, buprenorphine, or naltrexone treatment, alongside standard outpatient programs. Employing proven methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the facility customizes recovery strategies to each person's unique requirements. La Frontera Center is particularly adept at serving adult women and pregnant or postpartum women, and welcomes clients of all genders. Committed to high-quality care and individualized guidance, this center aims to support individuals in attaining sustained sobriety.

LHRC
Baton Rouge, LA

LHRC, located in Baton Rouge, LA, specializes in providing rehabilitation services specifically for adult women facing challenges related to substance use and requiring transitional housing. The center offers a range of programs, including intensive outpatient, long-term residential, and standard outpatient options, incorporating methods such as 12-step facilitation, anger management, and brief interventions. LHRC also supports individuals dealing with both substance use disorders and significant mental health concerns, particularly survivors of intimate partner violence and sexual abuse. With an emphasis on the needs of women, LHRC delivers comprehensive care to both older and younger adults.

La Frontera Center

Situated in Tucson, AZ, La Frontera Center delivers extensive long-term residential care for individuals facing addiction and dual mental health issues, catering to both adults and children. The facility offers round-the-clock support, emphasizing 12-step programs, anger management strategies, and short-term interventions. La Frontera Center is distinguished by its personalized treatment plans, accommodating adults and young adults of all genders. Dedicated to providing exceptional care, this center fosters a nurturing environment for individuals pursuing targeted assistance for their substance use and mental health difficulties.

La Frontera Center

La Frontera Center, situated in Tucson, AZ, is dedicated to providing expert care for adults struggling with addiction and co-occurring severe mental health conditions, as well as children experiencing emotional disturbances. This facility offers extended residential stays with continuous round-the-clock assistance. Employing proven therapeutic methods such as cognitive behavioral therapy and anger management, La Frontera Center also integrates contingency management and motivational incentives into its treatment plans. Their tailored programs are designed for adults and young adults of any gender. Emphasizing high-quality service and individualized support, this establishment distinguishes itself through its thorough treatment strategies and its dedication to fostering enduring recovery.

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La Amistad Behavioral Health Servs in Winter Park, FL, presents a full spectrum of care for those pursuing freedom from addiction and concurrent mental health challenges. They offer various levels of care, including hospital inpatient, intensive outpatient, and round-the-clock hospital inpatient services. Their therapeutic framework incorporates proven methods like 12-step support, anger management strategies, and brief intervention techniques. La Amistad is equipped to serve a broad demographic with distinct programs for adult men, women, and survivors of intimate partner violence. Catering to adults and young adults of all genders, the center is committed to delivering superior, tailored treatment designed to guide each person toward recovery and wellness.

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La Frontera Center, situated in Tucson, Arizona, delivers extensive treatment for substance use and expert care for those facing serious co-occurring mental health issues. The center features intensive outpatient programs and offers both outpatient services and treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, it serves adults and young adults across all genders. Notable programs focus on support for active military members, as well as specialized services for both adult men and women, ensuring personalized treatment for each client. La Frontera Center is committed to providing high-quality care and effective treatment plans to support individuals on their path to recovery.

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Wappingers Falls, NY

Situated in Wappingers Falls, NY, the LCR Southern Dutchess Clinic delivers a wide range of substance use therapies, including outpatient services, as well as methadone, buprenorphine, and naltrexone options. This center features specialized programs designed for active military members, teenagers, and adult males. Emphasizing 12-step support, anger management strategies, and brief intervention techniques, it accommodates individuals of all ages and genders. The clinic's dedication to high-quality care and customized treatment plans positions it as a reliable option for those pursuing effective addiction recovery solutions.

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Hicksville, NY

Situated in Hicksville, NY, LITC BH LLC provides dedicated rehabilitation services aimed at adults and young adults who are facing challenges related to substance use disorders and concurrent significant mental health issues. The facility offers a variety of programs such as intensive outpatient care, outpatient day treatment, and partial hospitalization, employing methods like 12-step facilitation and anger management techniques. Emphasizing personalized treatment, this center customizes its programs to cater to the specific requirements of each individual. Catering to both male and female participants, LITC BH LLC guarantees exceptional care through a diverse selection of treatment modalities, including short interventions, to aid individuals on their recovery journey.

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Situated in Charlotte, NC, LMS Medical Services PLLC specializes in outpatient treatment for adults and young adults grappling with both substance use disorders and significant mental health issues. The center employs customized methods in its care, offering services like 12-step facilitation, anger management, and short-term interventions. With distinct programs catering to both men and women, LMS Medical Services PLLC is recognized for its dedication to high-quality care and personalized treatment strategies. Whether clients need ongoing outpatient support or options involving methadone, buprenorphine, or naltrexone, this facility is committed to aiding individuals on their path to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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