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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Parallax Center Inc

Situated in New York, NY, Parallax Center Inc provides outpatient detox services, treatment for substance abuse, and outpatient care with methadone, buprenorphine, or naltrexone. The facility emphasizes cognitive behavioral therapy, motivational interviewing, and contingency management as part of its therapeutic offerings. It features distinctive programs designed for adult men, women, and the LGBTQ community. Catering to both adults and young adults, the center delivers customized treatment services for all genders. Parallax Center Inc distinguishes itself through its personalized addiction treatment strategies, prioritizing effective care and supportive experiences for individuals on their recovery journey in a diverse and welcoming setting.

Parham Doctors Hospital

Situated in Henrico, VA, Parham Doctors Hospital delivers a wide range of rehabilitation programs aimed at adults and young adults facing challenges with substance use and related mental health conditions. The center features outpatient services, day treatment, and partial hospitalization options designed to meet diverse individual requirements. Utilizing scientifically supported methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, clients partake in customized support for their recovery process. The facility, which specializes in addressing co-occurring disorders, offers programs for both men and women. Committed to providing high-quality care and individualized treatment plans, this center strives to assist individuals in achieving enduring sobriety and improved mental health.

Parkman Recovery Center

At Parkman Recovery Center in Warren, OH, we provide extensive addiction recovery programs designed exclusively for adult men. Our services encompass hospital-based inpatient detox, specialized substance use therapy, and supportive transitional living arrangements. We integrate proven therapeutic approaches like 12-step facilitation, anger management techniques, and cognitive behavioral therapy, serving adults of all ages who desire high-quality care. Our distinctive focus on the unique challenges faced by men allows for highly individualized treatment plans aimed at achieving enduring sobriety and successful community reintegration.

Partida Corona Medical Center

Partida Corona Medical Center, located in Las Vegas, NV, specializes in providing outpatient services aimed at detoxification, addressing substance use issues, and managing co-occurring disorders for both adults and minors. The facility offers various treatment options including outpatient detox, as well as methadone, buprenorphine, and naltrexone therapies. Emphasizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, the center is dedicated to delivering personalized care. They serve individuals of all ages and genders, ensuring their approach is uniquely tailored to each client's needs. Partida Corona Medical Center is committed to delivering high-quality, comprehensive addiction treatment in a nurturing atmosphere.

Partners Project Inc
Huntington Beach, CA

Located in Huntington Beach, CA, Partners Project Inc provides a wide range of rehabilitation services for both adults and young adults struggling with substance abuse and concurrent mental health challenges. The center features inpatient detoxification and treatment plans, with particular attention to the needs of active duty military members. Utilizing customized strategies like 12-step engagement and anger management therapy, the facility serves clients of all genders. The emphasis on short-term interventions guarantees personalized and effective care. Partners Project Inc is distinguished by its unwavering dedication to high-quality support and its mission to assist individuals in attaining sustainable recovery.

Partners Project Inc
Huntington Beach, CA

Partners Project Inc, located in Huntington Beach, CA, provides extensive addiction recovery programs designed for both adults and young adults dealing with substance use disorders and simultaneous mental health issues. The center offers a range of specialized services, including inpatient detox and round-the-clock hospital care, ensuring customized support through techniques such as 12-step facilitation, anger management, and brief intervention strategies. The facility features distinct programs for active duty military members as well as tailored options for adult men and women, promoting personalized treatment. With a strong focus on delivering high-quality care, this center is dedicated to assisting clients of all genders in attaining lasting recovery.

Pasadena Council on Alcoholism and

The Pasadena Council on Alcoholism provides a full spectrum of substance abuse recovery options designed to meet various requirements. Their offerings include structured intensive outpatient care, general outpatient services, and standard outpatient treatment, all grounded in proven methods like 12-step guidance, emotional regulation skills, and short-term counseling. Tailored programs are offered for young individuals, adult males, and adult females, serving a broad age range from youth to adults. This establishment is committed to personalized support, delivering excellent care to all male and female individuals pursuing a path to sobriety.

Passages Malibu
Malibu, CA

Passages Malibu, located in Malibu, CA, delivers a wide array of services aimed at treating addiction. With a focus on detoxification and substance abuse treatment, this center offers various residential programs that include round-the-clock care and short-term stays. Their methodology incorporates cognitive behavioral therapy, strategies for preventing relapse, and counseling for substance use disorders. Passages Malibu features specialized programs designed for adult men and women, along with clients who have faced traumatic experiences, ensuring a wide spectrum of support. By accommodating both adults and young adults, the center creates customized care plans for its male and female clients. Renowned for its high-quality treatment and personalized approach, Passages Malibu stands out as an excellent option for those in need of effective rehabilitation services.

Parent Care Family Recovery Center

The Parent Care Family Recovery Center, situated in La Mesa, CA, provides targeted substance abuse care for adult females and teenagers facing co-occurring mental health challenges. This center features intensive outpatient, outpatient, and standard outpatient treatment options, integrating 12-step facilitation, anger management techniques, and brief intervention strategies. Specialized services are offered for individuals affected by intimate partner violence. Catering to women of all ages, from adolescents to seniors, the center prioritizes excellent care in a nurturing atmosphere, serving as a vital resource for individuals pursuing holistic recovery.

Park Mental Health Treatment of

Park Mental Health Treatment in San Diego, CA, provides tailored support for adult men facing addiction and concurrent mental health challenges. The center offers robust partial hospitalization, intensive outpatient, and standard outpatient programs, serving adults across the age spectrum, including older adults and young adults. Their therapeutic modalities encompass 12-step integration, emotional regulation strategies, and short-term counseling. Park Mental Health Treatment distinguishes itself with specialized curricula for individuals with a history of trauma and those managing dual diagnoses. Emphasizing superior treatment and personalized recovery paths, this establishment is committed to guiding individuals toward lasting wellness.

Park Place Behavioral Healthcare

Park Place Behavioral Healthcare in Kissimmee, FL, delivers thorough substance abuse treatment for individuals of all ages struggling with addiction and associated mental health conditions. The facility provides various care levels, including intensive outpatient, extended residential stays, and standard outpatient services, with distinct programs designed for young people. Employing scientifically proven methods like 12-step support, brief counseling, and cognitive behavioral therapy, this center serves both men and women looking for high-caliber care in a nurturing setting. Park Place Behavioral Healthcare distinguishes itself through its integrated treatment plans customized for each person's specific circumstances, establishing it as a premier destination for effective and empathetic recovery assistance.

Park Center Inc
Bluffton, IN

Park Center Inc, located in Bluffton, IN, provides targeted outpatient services for adults dealing with substance use disorders and co-occurring mental health issues, as well as addressing significant emotional challenges in children. The center employs a variety of treatment methodologies, such as anger management, brief intervention sessions, and cognitive behavioral therapy. Additionally, unique programs are available for individuals who have faced traumatic experiences. With a strong emphasis on personalized care for both adults and children/adolescents, Park Center Inc is dedicated to offering tailored treatment plans for all clients. The facility prioritizes an individualized approach and utilizes evidence-based methods, reflecting its dedication to delivering exceptional rehabilitation services.

Parkview Behavioral Health

Parkview Behavioral Health, located in Fort Wayne, IN, provides extensive treatment options for both adults and children dealing with substance use challenges and associated mental health conditions. The center features hospital-based detox services, around-the-clock inpatient support, and intensive outpatient programs, accommodating individuals of all genders. With targeted services for those experiencing simultaneous mental health and addiction issues, the facility emphasizes the importance of 12-step programs, anger management strategies, and short-term therapeutic interventions. Parkview Behavioral Health is recognized for its personalized treatment plans and dedication to high-quality care, establishing itself as a leading provider of empathetic addiction recovery solutions in the Fort Wayne region.

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At Papilion Integrated Recovery Center located in Orem, Utah, individuals in need of thorough substance use treatment can access a variety of focused programs designed to meet their specific requirements. This center features options such as intensive outpatient care, outpatient day programs, and transitional housing, ensuring ongoing support for clients. Emphasizing 12-step support, anger management, and brief intervention strategies, the facility caters to numerous facets of the recovery process. Additionally, Papilion offers targeted programs for those who have faced trauma, intimate partner violence, sexual assault, and domestic abuse. Welcoming adults and young adults of all genders, Papilion Integrated Recovery Center is committed to delivering high-quality care and comprehensive healing for those on their path to recovery.

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Decatur, IN

Park Center Inc, located in Decatur, IN, offers a wide range of substance abuse treatment options for both adults and children dealing with concurrent mental health challenges. The facility provides various programs, including intensive outpatient, outpatient, and medication-assisted therapies, employing research-backed methods like cognitive behavioral therapy and anger management techniques. With a commitment to trauma-informed care, Park Center Inc serves individuals of all ages and genders, developing customized treatment strategies to foster enduring recovery. Prioritizing quality support and comprehensive healing, this center is a reliable choice for individuals in need of efficient rehabilitation services within a nurturing setting.

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Fort Wayne, IN

Park Center Inc, located in Fort Wayne, Indiana, stands out as a premier rehabilitation center that delivers tailored treatment for substance abuse as well as concurrent mental health issues in both adults and children. The facility encompasses both inpatient care and intensive outpatient services, utilizing proven methods such as 12-step programming, anger management strategies, and short-term interventions. Designed to meet the unique requirements of adolescents, adult males, and females, Park Center Inc supports a wide range of clients. With a dedication to providing holistic care, the center is dedicated to assisting both adult and youth clients in their recovery journey. Their focus on personalized treatment and high-quality services makes them a reliable option for those seeking to overcome challenges and achieve wellness.

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Columbia City, IN

Park Center Inc, located in Columbia City, IN, specializes in providing substance use treatment for adults with serious mental health disorders alongside children facing significant emotional challenges. The center offers various outpatient and intensive outpatient services, including treatments utilizing methadone/buprenorphine or naltrexone. With an emphasis on anger management, brief therapeutic interventions, and cognitive behavioral therapy, the facility is designed for those who have gone through traumatic experiences. Park Center Inc welcomes clients of all genders, ensuring personalized treatment for both adults and younger populations. Discover exceptional care and tailored programs at this well-appointed rehabilitation center.

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Park West Health System Inc, located in Baltimore, MD, provides focused treatment for adults struggling with substance use issues alongside mental health challenges, as well as for children facing significant emotional difficulties. The center's outpatient services feature intensive outpatient programs and medication-assisted treatment options, including methadone, buprenorphine, and naltrexone. Emphasizing techniques such as cognitive behavioral therapy, anger management, and quick therapeutic interventions, the facility delivers personalized care to active military members, teenagers, and adult males. Catering to a diverse population of adults and seniors, this center is dedicated to delivering high-quality care with customized treatment strategies aimed at fostering recovery and enhancing overall health.

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Parkside Outpatient Program in Astoria, NY, provides targeted care for adults struggling with substance use disorders, particularly when accompanied by serious mental health issues or emotional difficulties in younger individuals. This center delivers a range of services including intensive outpatient treatment, standard outpatient care, and medication-assisted options like methadone, buprenorphine, or naltrexone. They employ specialized therapeutic techniques such as 12-step facilitation, anger management, and brief interventions, serving adult men and women, as well as those with a history of trauma. The program is equipped to support both adult and pediatric/adolescent populations, offering personalized plans for both male and female participants. Parkside Outpatient Program is dedicated to delivering effective treatment, standing as a key provider for individuals pursuing recovery from addiction.

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Partners in Recovery/SPHS, situated in Rosedale, MD, delivers a full spectrum of addiction recovery solutions designed for adults and adolescents. Their services encompass safe detoxification, comprehensive substance use therapy, and tailored support for individuals managing both addiction and significant mental health challenges. Available treatment modalities include intensive outpatient programming, general outpatient services, and outpatient detoxification. Employing evidence-based strategies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center customizes treatment plans to address each person's unique journey. Specific programs are offered for active military personnel, adult men, and adult women. Partners in Recovery/SPHS is committed to providing high-quality care for all individuals, supporting both men and women on their path to wellness.

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Partners in Recovery/SPHS in Baltimore, MD, delivers complete addiction recovery programs for adults and younger adults. Their services encompass detoxification, treatment for substance dependency, and dedicated support for individuals facing both addiction and significant mental health challenges. Employing approaches like 12-step facilitation, brief intervention, and cognitive behavioral therapy, their offerings are customized to meet individual requirements. Specific tracks are available for active-duty military members, adult men, and adult women, providing targeted assistance. The facility provides outpatient and intensive outpatient care, emphasizing high-quality, personalized treatment for all clients, regardless of gender, on their journey to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)