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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Recovery Institute of Ohio

The Recovery Institute of Ohio, situated in Sandusky, OH, specializes in extensive treatment for substance use, transitional living options, and targeted assistance for individuals facing both substance use and significant mental health issues in adults, along with emotional challenges in children. This center features both inpatient hospital services and intensive outpatient care, emphasizing techniques such as 12-step programs, anger management strategies, and brief intervention methods. Customized programs are offered for adult men, adult women, and those who have undergone trauma. Catering to adults and young adults of any gender, the facility is dedicated to providing exceptional care and support for those on their path to recovery and wellness.

Recovery Life Group LLC
Upper Marlboro, MD

Recovery Life Group LLC, situated in Upper Marlboro, MD, provides focused interventions for individuals grappling with addiction and dual diagnoses affecting adults and youth. The facility encompasses several care models, such as acute inpatient care, round-the-clock residential stays, and extended therapeutic housing. Employing methodologies like 12-step support, motivational interviewing, and cognitive restructuring, the center crafts personalized recovery plans. Distinctive services are available for active military personnel, as well as adult men and women. Catering to a diverse clientele including adults and adolescents of all genders, Recovery Life Group LLC is dedicated to delivering exceptional, all-encompassing support within a nurturing atmosphere.

Recovery Pathways LLC
Ortonville, MI

Situated in Ortonville, Michigan, Recovery Pathways LLC delivers outpatient services for substance use disorders. They have particular expertise in treating adults with co-occurring substance use and significant mental health conditions, as well as addressing emotional disturbances in children. The facility offers medication-assisted treatment, including methadone, buprenorphine, or naltrexone, alongside standard outpatient support. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Recovery Pathways LLC also features specialized programs for active military personnel, adult men, and adult women, serving adults and young adults of all genders. For personalized and effective treatment, consider Recovery Pathways LLC.

Recovery Pathways LLC
Essexville, MI

Nestled in Essexville, Michigan, Recovery Pathways LLC provides extensive outpatient services for adults managing substance use disorders, particularly those with co-occurring serious mental health conditions. The center's expertise lies in outpatient medication-assisted treatment, including methadone, buprenorphine, and naltrexone. Their therapeutic interventions incorporate methods such as 12-step program support, anger management techniques, and brief intervention strategies. Recovery Pathways LLC also offers specialized programming for active duty military members, young people, and adult males, demonstrating a commitment to diverse needs. Serving adults and children across all genders, Recovery Pathways LLC is dedicated to delivering high-quality care to aid individuals in their pursuit of lasting recovery.

Recovery Research Network Foundation

Situated in West Palm Beach, FL, the Recovery Research Network Foundation delivers outpatient treatment for substance use disorders in adults, while also addressing co-occurring mental health issues for those facing significant emotional challenges. This center features dedicated programs for adult men and women, as well as services aimed at individuals impacted by intimate partner violence. Emphasizing 12-step principles, anger management, and targeted brief interventions, the center customizes its treatment approaches to cater to each person's unique requirements. Offering outpatient options for methadone/buprenorphine or naltrexone therapy, the facility provides comprehensive support for its clients. It serves a diverse demographic, including both adults and young adults, by delivering effective, gender-sensitive treatment for individuals on their recovery journey.

Recovery Point of Huntington

Nestled in Huntington, WV, Recovery Point of Huntington is dedicated to providing extensive recovery support, concentrating on addiction treatment and dual diagnoses for all age groups. This facility offers intensive outpatient, extended residential stays, and standard outpatient services, employing methodologies like 12-step facilitation, brief intervention, and cognitive behavioral therapy. Tailored services are available for adult males, individuals with past trauma, and those experiencing concurrent mental health challenges. Catering to adults, older adults, and younger adults, this center offers specific support exclusively for male patients. Emphasizing superior care and scientifically-backed methods, Recovery Point of Huntington is recognized as a reliable choice for comprehensive recovery.

Recovery Place Community Services

Located in Savannah, GA, Recovery Place Community Services offers a comprehensive range of addiction treatment services. The center specializes in detoxification and substance use treatment for adults and young adults. With treatment formats including intensive outpatient, outpatient, and day treatment, this facility provides tailored care for individuals at various stages of recovery. Utilizing approaches such as 12-step facilitation, anger management, and brief intervention, the program caters to clients with co-occurring mental health and substance use disorders. Notably, Recovery Place Community Services also offers specialized programs for those who have experienced intimate partner violence, domestic violence, and forensic clients. With a focus on quality care and individualized treatment plans, this center is dedicated to supporting clients on their journey to recovery.

Recovery Network of Programs Inc

Recovery Network of Programs Inc, situated in Stratford, CT, provides extensive support for individuals of all ages grappling with substance use disorders, including those with co-occurring mental health challenges. Their offerings encompass robust outpatient programs, standard outpatient services, and targeted medication-assisted treatments utilizing methadone, buprenorphine, or naltrexone. Emphasizing strategies like 12-step recovery, emotional regulation skills, and short-term counseling, this establishment serves adult men and women, and individuals with a history of trauma. The center is committed to delivering gender-specific, personalized treatment plans designed to address the unique requirements of each person.

Recovery Keys
Jacksonville, FL

Recovery Keys, situated in Jacksonville, FL, delivers holistic addiction recovery solutions for adults and adolescents. This establishment features detoxification services, addiction treatment, and dedicated support for those facing dual mental health diagnoses. Employing strategies like cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques, Recovery Keys offers intensive outpatient, outpatient, and partial hospitalization options. Their personalized plans are designed for adult males, adult females, and individuals with co-occurring conditions, ensuring a tailored recovery journey. Prioritizing excellence and client-specific care, this center supports both male and female individuals pursuing successful rehabilitation.

Recovery Now LLC
Louisville, KY

Situated in Louisville, KY, Recovery Now LLC delivers extensive substance abuse treatment alongside transitional housing options. This center features various programs, including intensive outpatient treatment, outpatient day care, and partial hospitalization. Utilizing targeted methods such as 12-step facilitation, anger management, and brief interventions, Recovery Now LLC addresses the needs of active military members as well as adult men and women. Catering to both adults and children/adolescents, the facility provides gender-specific programs designed for males and females. At Recovery Now LLC, you will find dedicated care and personalized strategies aimed at achieving effective addiction recovery and smooth reentry into everyday life.

Recovery Now LLC
Louisville, KY

Nestled in Louisville, KY, Recovery Now LLC provides a complete spectrum of care for individuals battling addiction. Their offerings encompass medically supervised detox, robust substance use disorder treatment, and supportive housing solutions like halfway houses and sober living residences. Recovery Now LLC emphasizes intensive outpatient care and day programs, employing proven methods such as 12-step engagement, anger management techniques, and concise therapeutic interventions. They also feature specialized tracks for active military members, adults of all genders, and young people, with distinct services for males and females. Recovery Now LLC is dedicated to delivering personalized, high-quality support, serving as a crucial beacon of hope for those on their journey to wellness.

Recovery Revolution Inc

Situated in Bangor, PA, Recovery Revolution Inc delivers a wide range of substance abuse rehabilitation for both adults and children facing serious mental health challenges. The center offers a variety of treatment options including intensive outpatient, outpatient, and standard outpatient programs. Emphasizing 12-step support, anger management, and brief intervention strategies, Recovery Revolution Inc serves adolescents as well as adult men and women. The programs are specifically designed for adults and seniors of all genders. Renowned for its exceptional care and targeted services, this facility is committed to supporting individuals on their path to recovery.

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Recovery Network of Programs Inc, situated in Bridgeport, CT, provides a full range of addiction recovery services designed for both adults and young adults. This center offers intensive outpatient programs, detoxification services on an outpatient basis, and various other outpatient options. Its expertise lies in addressing substance use disorders alongside mental health challenges and trauma. The center employs a 12-step approach, anger management techniques, and brief interventions, serving both male and female participants. There are specialized programs available for adult men, adult women, and those who have faced trauma, ensuring individualized and high-quality treatment experiences.

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Recovery Pathways LLC, located in Gladwin, MI, provides outpatient services tailored to adults struggling with substance use issues and serious mental health disorders, as well as addressing emotional challenges in children. The center emphasizes a 12-step approach, anger management techniques, and brief interventions. It offers specialized programs aimed at active duty military personnel and both men and women. Designed to accommodate adults and young adults of all genders, the facility features outpatient treatments such as methadone/buprenorphine or naltrexone, alongside standard outpatient options. Recovery Pathways LLC is committed to supporting individuals on their journey to sustainable recovery through comprehensive, evidence-based methods.

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Recovery Pathways LLC in Corunna, MI, is dedicated to providing diverse outpatient services for individuals facing challenges with substance use and co-occurring mental health conditions. Our programs are designed for adults with substance use disorders and mental health issues, as well as children experiencing emotional disturbances. We offer specialized support for active-duty military members, adolescents, and adult men. Our therapeutic approaches encompass 12-step facilitation, anger management, and brief intervention strategies. Recovery Pathways LLC is committed to delivering high-quality, personalized care for both male and female clients across various age demographics. We also provide outpatient treatment options including methadone, buprenorphine, and naltrexone, ensuring a comprehensive recovery journey tailored to each individual's unique requirements.

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Recovery Pathways LLC, located in Midland, MI, specializes in outpatient treatment for substance use issues and offers focused support for individuals with concurrent substance use and mental health disorders in adults, as well as emotional challenges in children. Their services feature outpatient care using methadone, buprenorphine, or naltrexone, along with 12-step programs, anger management sessions, and brief intervention strategies. This center provides customized care for active military personnel, as well as for men and women over 18. Recovery Pathways LLC is dedicated to delivering comprehensive care and assistance to all individuals, regardless of gender, who are striving for recovery.

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Mount Pleasant, MI

Recovery Pathways LLC, situated in Mount Pleasant, MI, delivers outpatient programs for individuals battling substance use disorders. They also specialize in comprehensive care for adults with co-occurring mental health issues and children experiencing emotional disturbances. Their services include outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, alongside standard outpatient therapy. Emphasizing approaches like 12-step facilitation, anger management techniques, and brief intervention strategies, the center customizes treatment plans to meet specific patient needs. Distinct programs are available for active military members, adult men, and adult women. Recovery Pathways LLC welcomes adults and young adults of all genders, committed to providing effective support throughout the recovery process.

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Savannah, GA

Situated in Savannah, GA, Recovery Place Inc provides a wide array of services aimed at treating addiction. The facility offers detox services, treatment for substance use disorders, and focused care for those facing both substance use challenges and significant mental health conditions. Treatment options consist of intensive outpatient programs, long-term residential treatments, and traditional outpatient services. Recovery Place Inc employs evidence-backed methodologies, including 12-step programs, anger management, and cognitive behavioral therapy. With specialized programs for adult men, women, and individuals with trauma histories, this center addresses the needs of a varied clientele. Catering to adults and young adults of all genders, Recovery Place Inc commits to delivering high-quality care and assistance for individuals on their journey to recovery from addiction.

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Hinesville, GA

Situated in Hinesville, GA, Recovery Place Inc provides extensive treatment options for both adults and young adults facing substance use challenges. This center focuses on addressing co-occurring substance use issues along with significant mental health conditions or emotional challenges. Offering a variety of outpatient services such as intensive outpatient programs, 12-step facilitation, anger management sessions, and cognitive behavioral therapy, the facility is designed to meet the specific needs of its male and female clientele. Specialized programs for adult men, adult women, and survivors of sexual abuse ensure personalized attention. Recovery Place Inc is committed to delivering exceptional and empathetic care to assist clients in their recovery journey.

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Savannah, GA

Recovery Place Inc, situated in Savannah, GA, delivers a full spectrum of addiction recovery support for adults and adolescents. The facility provides detoxification, treatment for substance abuse, and tailored assistance for those dealing with co-occurring psychological conditions. Treatment modalities encompass intensive outpatient, outpatient, and day treatment programs. Recovery Place Inc utilizes proven therapeutic methods, including 12-step facilitation, anger management, and cognitive behavioral therapy, to foster lasting recovery. Distinct programs are available for individuals with a history of trauma and those with co-occurring disorders. Committed to high-quality care, this institution assists both men and women in their journey toward successful rehabilitation.

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Recovery Services of NW Ohio, located in Fayette, OH, provides a wide range of treatment options for substance use and specialized services for individuals dealing with concurrent mental health issues. The center features long-term and short-term residential programs, as well as 24-hour residential care, aimed at both adults and young adults. Employing scientifically-backed methods such as cognitive behavioral therapy and motivational interviewing, the facility also provides specialized programs catering to adult women, trauma survivors, and those with dual diagnoses. With a commitment to supporting female clients, this center strives to deliver exceptional care and assistance for those on the path to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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