NWVCIL Logo
Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6711 results

Sierra Tucson
Tucson, AZ

Sierra Tucson, situated in Tucson, Arizona, provides extensive support for adults and young adults dealing with substance use issues alongside mental health challenges. The center features inpatient detox services and various treatment programs, including targeted assistance for individuals with past trauma or experiences of sexual abuse. With an emphasis on 12-step programs, anger management, and short-term interventions, Sierra Tucson serves both men and women, including active military members. Renowned for its exceptional care and personalized treatment plans, this center stands out as a leading option for individuals in need of empathetic rehabilitation solutions.

Signature Health Inc
Willoughby, OH

Located in Willoughby, OH, Signature Health Inc provides a wide array of services for adults and seniors struggling with addiction. Their offerings encompass detox services, treatment for substance use disorders, and support for individuals facing both substance use and significant mental health challenges in adults or severe emotional issues in children. The center utilizes various treatment modalities, including intensive outpatient, outpatient, and day treatment programs, ensuring that care is customized to meet individual needs through methods such as cognitive behavioral therapy and motivational interviewing. Signature Health Inc is dedicated to delivering quality care tailored for both male and female patients, making it an excellent option for those in search of effective and personalized treatment for addiction.

Signature Health Inc

Situated in Beachwood, OH, Signature Health Inc delivers extensive services for addiction recovery aimed at adults and seniors. This center specializes in detoxification, treatment for substance use disorders, and offers tailored assistance for individuals facing concurrent substance use and significant mental health challenges, as well as serious emotional disturbances in children. The program encompasses options such as intensive outpatient care, standard outpatient services, and day treatment. Emphasizing techniques like brief intervention, cognitive-behavioral therapy, and motivational interviewing, Signature Health Inc customizes treatment plans to meet the unique needs of each client. The facility is recognized for its personalized approach, providing high-quality care for both men and women in their journey to overcome addiction.

Signature Health Inc

Located in Ashtabula, OH, Signature Health Inc provides a wide variety of rehabilitation services. The center focuses on detoxification and treatment for substance use disorders, while also addressing the needs of those with concurrent serious mental health challenges or emotional issues. Treatment options are available in formats such as intensive outpatient, outpatient, and partial hospitalization, with a strong emphasis on evidence-based methods like cognitive behavioral therapy and motivational interviewing. What distinguishes Signature Health Inc is its commitment to creating customized programs for each individual. Catering to adults and seniors of any gender, the center prioritizes delivering top-notch care with a strong emphasis on individualized treatment strategies to facilitate effective recovery.

Silicon Valley Recovery

Silicon Valley Recovery, located in San Jose, CA, provides a wide range of addiction treatment options for both adults and young adults. This facility features long-term residential programs, detoxification services, and around-the-clock residential assistance. Emphasizing 12-step methodologies, anger management strategies, and brief intervention techniques, the center customizes its treatment plans to meet the unique requirements of each individual. There are specialized programs designed for both adult men and women, fostering a nurturing and inclusive atmosphere. The committed team at Silicon Valley Recovery delivers high-quality support for clients of all genders, positioning it as an exceptional option for those in need of effective substance abuse treatment and detoxification in the Silicon Valley region.

Silver Linings Recovery Center

Silver Linings Recovery Center, situated in Langhorne, PA, provides extensive care for individuals struggling with substance use. The center focuses on addressing co-occurring mental health challenges in adults and emotional difficulties in children alongside substance dependency. Their therapeutic offerings encompass intensive outpatient, outpatient, and day treatment programs, all delivered with personalized support. Utilizing methods like 12-step facilitation, anger management, and brief interventions, Silver Linings Recovery Center distinguishes itself through its dedicated programs for those with dual diagnoses of mental and substance use disorders, serving both men and women with an emphasis on superior care and overall well-being.

Silver Pines Treatment Center

Silver Pines Treatment Center, situated in Mahanoy City, PA, delivers extensive support for those in need of detox and addiction treatment. Services include round-the-clock hospital inpatient detoxification and residential detoxification. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this establishment serves active military, adult men and women, and individuals across different age demographics, including young adults. By offering individualized programs designed for specific gender and age considerations, Silver Pines Treatment Center guarantees top-tier assistance and care for everyone pursuing sobriety.

Silver Ridge
Mills River, NC

Nestled in Mills River, NC, Silver Ridge provides a complete suite of substance abuse recovery services for adults and adolescents. The facility excels in addressing dual diagnoses, offering intensive outpatient care, extended residential stays, and standard outpatient programs. Employing proven methods such as cognitive behavioral therapy and anger management techniques, Silver Ridge customizes recovery journeys to suit each person's unique requirements. Featuring dedicated programs for active military members, adult males, and adult females, the center cultivates a nurturing atmosphere for everyone. Committed to superior care centered on comprehensive well-being, Silver Ridge stands as a reliable choice for individuals pursuing effective and empathetic addiction recovery.

Silver Sands Recovery

Silver Sands Recovery in Prescott, AZ, provides thorough addiction treatment and expert support for individuals facing dual diagnoses of mental health conditions. This center offers structured outpatient services, incorporating 12-step principles, cognitive behavioral strategies, and techniques for managing anger. Emphasizing supportive transitional housing and sober living options, Silver Sands Recovery serves adult men and women, along with young adults. Their specialized care for co-occurring disorders guarantees personalized treatment plans. Opt for Silver Sands Recovery for effective, gender-tailored care in a peaceful Arizona location.

Silver Hill Hospital Inc

Silver Hill Hospital Inc, located in New Canaan, CT, offers dedicated inpatient services aimed at detoxification, treatment for substance use, and addressing co-occurring mental health issues for both adults and children. The center emphasizes 12-step approaches, anger management, and short-term interventions, providing thorough care for those facing trauma, substance use challenges, and mental health concerns. With specialized programs for teenagers and individuals with dual diagnoses, they ensure that treatment is personalized. Silver Hill Hospital Inc is committed to delivering effective, gender-sensitive care that promotes recovery and holistic well-being for all clients, regardless of age or gender.

Sierra Vista Hospital
Sacramento, CA

Sierra Vista Hospital in Sacramento, CA, delivers a complete spectrum of addiction recovery care for individuals of all ages. This institution features hospital-based inpatient detoxification and therapeutic programs designed to address substance use disorders, even those complicated by co-occurring mental health conditions. Employing scientifically validated methodologies such as 12-step facilitation, cognitive behavioral therapy, and specialized substance use disorder counseling, Sierra Vista Hospital crafts personalized treatment plans. Distinct programs are available for active duty military members, teenagers, and adult women. Prioritizing high-quality care and specialized services for various demographics, Sierra Vista Hospital is committed to guiding patients toward enduring sobriety.

Sinnissippi Centers Inc

Sinnissippi Centers Inc., located in Rochelle, IL, delivers thorough support for substance use disorders, including dedicated services for those facing concurrent serious mental health conditions or emotional challenges. Their offerings encompass intensive outpatient, outpatient, and medication-assisted treatment options (methadone/buprenorphine or naltrexone), all grounded in proven methods such as 12-step facilitation, anger management, and brief intervention. The center features distinct programs designed for adolescents, adult men, and adult women, and welcomes adults and seniors of any gender. Prioritizing high-quality, personalized care, Sinnissippi Centers Inc. is committed to guiding individuals through their recovery process.

Silver Maple Recovery

Situated in Lorain, OH, Silver Maple Recovery stands out as a premier rehabilitation center dedicated to providing hospital inpatient detox and treatment services specifically for adult males. The facility emphasizes 12-step support, anger management strategies, and short-term intervention methods to assist clients dealing with both mental health issues and substance use disorders, including those who have faced trauma. Silver Maple Recovery serves a diverse demographic of adult men, ranging from young adults to seniors. With a strong emphasis on personalized care and high-quality treatment, this center fosters a nurturing atmosphere for individuals looking to address their substance use difficulties.

Sinnissippi Centers Inc

Sinnissippi Centers Inc, located in Dixon, IL, provides targeted treatment for adults dealing with substance use issues and serious co-occurring mental health disorders, as well as for children facing emotional challenges. The center offers both intensive outpatient and standard outpatient services, including methadone and buprenorphine options. By implementing 12-step strategies, anger management techniques, and brief therapy sessions, the facility supports a diverse clientele, including adult men and women, adolescents, and seniors, with dedicated programs tailored for each gender. Emphasizing personalized care and evidence-driven methods, the center aims to deliver effective treatment to those in pursuit of recovery from addiction and mental health difficulties.

Sinnissippi Centers Inc

Sinnissippi Centers Inc, situated in Sterling, IL, delivers comprehensive rehabilitation programs. The facility excels in addressing addiction, supporting adults with co-occurring mental health conditions and children facing significant emotional challenges. Services are available in intensive outpatient and standard outpatient formats, with medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Program methodologies encompass 12-step facilitation, anger management techniques, and brief intervention strategies. Sinnissippi Centers Inc features tailored programs for active military members, teenagers, and adult men. Catering to individuals of all ages, including seniors, and both genders, the center is dedicated to providing personalized care and encouragement for individuals on their recovery journey.

Silver Creek Clinic

Situated in Orem, UT, Silver Creek Clinic provides a wide range of outpatient rehabilitation services with a focus on detoxification and the treatment of substance use disorders. The center employs various methods, including anger management, cognitive behavioral therapy, and motivational incentives, to support adult men and women, including individuals living with HIV or AIDS. Designed to meet the diverse needs of adults and young adults across genders, Silver Creek Clinic fosters a nurturing environment for those on the path to recovery. The center offers personalized outpatient detoxification and treatment options featuring methadone, buprenorphine, or naltrexone. Opt for Silver Creek Clinic for high-quality, evidence-based care in a friendly atmosphere.

Sims Kemper Clinical Counseling and

Sims Kemper Clinical Counseling in Topeka, KS, provides extensive addiction recovery services via its intensive, standard outpatient, and general outpatient tracks. They excel in 12-step support, emotional regulation techniques, and short-term counseling strategies, serving young individuals and adults of all genders, including seniors. This establishment prioritizes personalized support for a wide spectrum of recovery requirements. Their dedication to superior treatment and customized plans positions Sims Kemper Clinical Counseling as a premier option for individuals desiring successful dependency recovery within a nurturing setting.

Sinnissippi Centers Inc

Sinnissippi Centers Inc, located in Freeport, IL, provides a wide range of services for people dealing with substance use disorders, along with specialized support for those facing both substance use and significant mental health challenges. The center features multiple treatment options, including intensive outpatient initiatives and outpatient services utilizing methadone, buprenorphine, or naltrexone. By emphasizing 12-step programs, anger management, and short intervention strategies, it serves active military members, teenagers, and adult males. Sinnissippi Centers Inc is committed to offering top-notch, gender-sensitive care that addresses the specific requirements of each person, including adults and seniors of any gender.

Sinnissippi Centers Inc
Mount Carroll, IL

Sinnissippi Centers Inc, located in Mount Carroll, Illinois, delivers a wide range of services for individuals struggling with substance use issues and co-occurring mental health disorders. The facility specializes in intensive outpatient programs, outpatient care, and medication-assisted treatments involving methadone, buprenorphine, or naltrexone. It emphasizes 12-step support, anger management techniques, and brief intervention strategies. Catering to diverse populations, including adults, seniors, active-duty military personnel, adolescents, and adult males, the center provides customized treatment plans for both genders. With a strong dedication to high-quality, evidence-informed care, Sinnissippi Centers Inc is recognized as an excellent option for those in need of effective rehabilitation solutions.

Placeholder image

Sierra Transformation Center in Las Vegas, NV, provides focused outpatient services for adults and youth dealing with addiction and co-occurring mental health conditions. Employing evidence-based methods such as 12-step guidance, cognitive behavioral strategies, and short-term counseling, the center delivers personalized support. Their programs are designed for active military personnel, teenagers, and adult men. Sierra Transformation Center is committed to delivering high-standard care for both men and women seeking thorough recovery assistance in a nurturing setting. They offer individualized approaches for outpatient detox and maintenance treatments like methadone and buprenorphine, aiming for sustained healing.

Placeholder image

Sinnissippi Centers Inc. in Amboy, Illinois, delivers extensive substance abuse recovery programs specifically designed for adult women facing addiction and concurrent mental health conditions. The center has developed unique support systems for those who have endured intimate partner abuse, domestic violence, or sexual assault. Their therapeutic approach emphasizes 12-step integration, strategies for managing anger, and rapid intervention techniques, offering both intensive outpatient and standard outpatient care. Sinnissippi Centers Inc. serves adult women across various age groups, including seniors and young adults, providing personalized assistance to clients striving for recovery from addiction and mental health issues in a nurturing setting.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)