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Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Solstice Counseling and Wellness Ctr

Located in Pemberton, NJ, Solstice Counseling and Wellness Center provides dedicated treatment for adults experiencing substance use issues alongside severe mental health challenges, as well as emotional difficulties in children. The facility offers comprehensive outpatient services, which encompass methadone/buprenorphine and naltrexone therapies. Emphasizing approaches such as 12-step programs, anger management, and short-term interventions, the center serves active military members as well as men and women. Catering to both adults and young adults of all genders, Solstice Counseling and Wellness Center is committed to delivering high-quality care through customized programs that effectively meet individual requirements.

Solstice Health and Wellness

Solstice Health and Wellness, located in Sarasota, FL, delivers a broad spectrum of outpatient services aimed at helping individuals on their journey to recovery from substance use disorders. The center includes detox services, treatment for substance use, and dedicated support for those facing co-occurring serious mental health challenges or emotional issues. Emphasizing approaches such as 12-step support, brief interventions, and cognitive behavioral therapy, this facility serves adult men and women, including clients with histories of intimate partner or domestic abuse. Customized programs for young adults ensure personal attention, while outpatient detox and medication-assisted treatment further elevate the standard of care provided.

SolutionsRetreat Inc

SolutionsRetreat Inc, located in Nashville, TN, delivers extensive long-term residential therapy programs that focus on detox, addiction recovery, and addressing co-occurring mental health issues for both adults and children. The facility offers round-the-clock support while emphasizing 12-step programs, anger management techniques, and short-term intervention strategies. They also provide distinctive services for adult males, veterans, and survivors of intimate partner violence. By offering specialized programs for seniors and young adults, along with a dedicated approach for men, SolutionsRetreat Inc is committed to providing personalized and efficient treatment for individuals on their path to recovery.

Sonoma Recovery Services LLC

Sonoma Recovery Services LLC, located in Petaluma, California, provides a wide array of treatment options aimed at assisting individuals on their recovery path. The center offers detox services, treatment for substance use disorders, and tailored support for adults facing co-occurring mental health issues or serious emotional challenges in children. With flexible programs that include intensive outpatient care, long-term residential options, and standard outpatient services, the facility meets various needs. Sonoma Recovery Services LLC employs methodologies like 12-step programs, anger management techniques, and cognitive behavioral therapy to ensure personalized treatment. Additionally, specialized programs are available for adult men, adult women, and those who have gone through intimate partner or domestic violence. This center is committed to delivering high-quality care and fostering holistic wellness for all clients, including adults and young adults of any gender.

Solas Health PLLC

Solas Health PLLC, situated in Raleigh, NC, specializes in treatment programs for substance use, serving both adults and young adults. This rehabilitation center emphasizes outpatient services, offering a variety of options, including outpatient methadone/buprenorphine or naltrexone treatments, along with standard outpatient care. The facility employs evidence-based practices, integrating anger management, cognitive behavioral therapy, and counseling for substance use disorders to aid clients in their recovery journey. Solas Health PLLC also provides targeted programs for men and women, as well as for individuals facing co-occurring mental health and substance use challenges, ensuring that care is of a high standard and caters to the unique needs of each client.

Solas Health PLLC
Lumberton, NC

Solas Health PLLC, located in Lumberton, NC, delivers outpatient services for individuals struggling with substance use. Their primary objective is to offer superior support to adults and young adults. The center features distinct programs tailored for adult men, adult women, and individuals experiencing co-occurring mental health and substance use issues. Treatment modalities employed include anger management, cognitive behavioral therapy, and contingency management/motivational incentives. Solas Health PLLC provides outpatient options utilizing methadone, buprenorphine, or naltrexone, in addition to standard outpatient care. Dedicated to personalized treatment, this facility serves both male and female clients in their pursuit of effective and customized addiction recovery solutions.

Solstice Counseling and Wellness Ctr

Solstice Counseling and Wellness Center located in Deptford, NJ, provides a variety of tailored treatment options aimed at assisting individuals facing challenges related to substance abuse and co-occurring mental health issues. This center offers intensive outpatient programs, general outpatient services, and medication-assisted treatment options utilizing methadone, buprenorphine, or naltrexone. Emphasizing 12-step methods, anger management, and short interventions, the center serves active duty military members along with adult men and women. Committed to helping adults and young adults of diverse backgrounds, the center focuses on delivering personalized, high-quality care to foster enduring recovery and improve emotional health.

Social Science Services Inc

Social Science Services Inc, situated in Bloomington, CA, provides extensive rehabilitation services with a focus on treating substance abuse and co-occurring mental health issues. The facility offers multiple treatment options, including long-term and short-term residential programs, as well as 24-hour supervision. Emphasizing techniques such as 12-step programs, anger management, and cognitive behavioral therapy, the center creates personalized treatment plans that address unique needs. With specializations in trauma support and services for pregnant and postpartum women, it serves adult, senior, and young adult female clients. Social Science Services Inc is committed to delivering high-quality, gender-responsive care to aid individuals in their recovery journey.

Social Science Services Inc

Social Science Services Inc in Bloomington, CA, delivers extensive addiction recovery programs. They offer detoxification, substance abuse therapy, and targeted support for adults with dual diagnoses of substance abuse and severe mental health conditions, or children with significant emotional disturbances. Patients benefit from customized treatment plans within long-term residential, outpatient, and standard outpatient settings. The facility utilizes proven methods like 12-step integration, anger management training, and cognitive behavioral therapy. Distinct programs are available for adult males, adult females, and individuals with trauma histories. Catering to both male and female adults and young adults, this establishment is dedicated to providing effective recovery support.

Somerdale Treatment Services

Somerdale Treatment Services, located in Somerdale, NJ, offers tailored programs for adults and young adults dealing with substance use issues. The center specializes in various care options, including intensive outpatient programs, general outpatient support, and medications such as methadone/buprenorphine or naltrexone. Committed to individualized treatment, it emphasizes techniques like 12-step facilitation, anger management, and brief intervention strategies. The facility also features distinct programs designed for active military members, as well as specific offerings for adult men and women. Providing a nurturing and inclusive atmosphere, Somerdale Treatment Services caters to both male and female clients on their journey to recovery from substance use disorders.

Social Model Recovery Systems

Social Model Recovery Systems, situated in Los Angeles, California, delivers extensive support for individuals battling substance use disorders, particularly those facing co-occurring serious mental health conditions or emotional challenges. The facility offers a range of residential options, including extended, brief, and round-the-clock care. Their therapeutic methodologies incorporate 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Targeted interventions are available for adult men, women, and survivors of intimate partner or domestic violence. This center is dedicated to providing high-quality, personalized care for adult and young adult clients of all genders, fostering their journey toward recovery and well-being.

Social Recovery Center
Springfield, NJ

Social Recovery Center in Springfield, NJ, delivers tailored support for adults navigating the complexities of addiction alongside significant mental health concerns, or for children experiencing emotional distress. The center provides various levels of care, including intensive outpatient, standard outpatient, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their approach emphasizes principles of 12-step programs, strategies for managing anger, and short-term counseling techniques. This establishment is equipped to assist adult men and women, including individuals who have experienced domestic violence. Accommodating both adults and young adults of all genders, Social Recovery Center designs personalized plans to offer complete assistance and guidance to individuals pursuing healing from substance dependence and mental well-being issues.

Sojourner Recovery Services

Sojourner Recovery Services located in Hamilton, OH, provides a wide variety of treatment options for individuals dealing with substance use issues and related mental health disorders in both adults and children. The center's offerings encompass intensive outpatient programs, outpatient services, and day programs. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational incentives, they offer targeted services to active duty military members, teenagers, and adult males. Sojourner Recovery Services is dedicated to offering exceptional care tailored to the specific requirements of all adults and young people, regardless of gender, and aims to foster enduring recovery.

Social Model Recovery Systems

Social Model Recovery Systems in Covina, CA, provides extensive support for adults and young adults overcoming substance dependence. Their programs are adept at managing dual diagnoses, where substance abuse intersects with significant mental health challenges. Offering various levels of care including intensive outpatient and regular outpatient services, they deliver personalized treatment. This is achieved through methods like anger management, brief intervention, and cognitive behavioral therapy. They also specifically support adult men, adult women, and individuals with trauma histories, fostering a secure and understanding atmosphere. For those pursuing effective recovery, this center stands out as a leading option.

Sol Medical Group
Wake Forest, NC

Situated in Wake Forest, NC, Sol Medical Group provides extensive outpatient services for individuals struggling with substance use disorders alongside severe mental health challenges. The center features tailored programs for teens, men, and women. Treatment methods encompass brief interventions, community reinforcement with incentives, and strategies for preventing relapse. Committed to delivering high-quality care, Sol Medical Group serves both male and female clients, offering outpatient options such as methadone/buprenorphine or naltrexone therapy alongside general outpatient services. This center invites adults and older adults in search of impactful rehabilitation solutions within a nurturing setting.

Solas Health PLLC
Pinehurst, NC

Solas Health PLLC, located in Pinehurst, NC, provides extensive treatment options for substance use disorders through outpatient services, which include methadone, buprenorphine, and naltrexone therapies. The center focuses on cognitive behavioral therapy, counseling for substance use issues, and offers telemedicine options as well. It features customized programs for active military personnel, as well as specific tracks for adult men and women. Solas Health PLLC serves both adults and young adults of all genders, ensuring personalized care within a nurturing setting. Clients can look forward to receiving high-quality treatment from skilled professionals, establishing Solas Health PLLC as a leading option for those in need of specialized addiction recovery support.

Sol Medical Group

Sol Medical Group in Durham, NC, provides focused outpatient care for individuals of all ages dealing with addiction and related mental health challenges. They offer diverse treatment options, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach emphasizes short-term interventions, building supportive community connections, and equipping patients with tools to avoid relapse. Sol Medical Group has distinct programs for teenagers, adult men, and women, and welcomes adults and older adults of any gender, making them a key provider of extensive recovery services in Durham.

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Social Model Recovery Systems, situated in El Monte, CA, stands out as a leading rehabilitation facility that focuses on detoxification and treatments for substance abuse. This center provides residential detox services and around-the-clock care specifically designed for adult men on their recovery journey. Emphasizing 12-step programs, anger management, and brief intervention strategies, the center is equipped to support active duty military members, adult males, and victims of intimate partner violence. Catering to adults, seniors, and young adults, this establishment fosters a nurturing atmosphere for male clients aiming to conquer addiction and reclaim their lives.

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Social Model Recovery Systems in El Monte, CA, provides extensive addiction treatment within a nurturing residential environment. They offer various residential program lengths for adult men struggling with addiction, including options for extended stays, shorter durations, and immediate, around-the-clock care. Their expertise lies in guiding clients through 12-step programs, anger management techniques, and cognitive behavioral therapy, specifically assisting those affected by domestic or intimate partner violence. The center also serves active duty military members, adult males, and individuals across all age groups, prioritizing personalized care and proven therapeutic methods to support successful recovery from substance dependency.

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Sojourners Recovery, located in Lake Mary, FL, delivers an extensive range of treatment options for both adults and children/adolescents facing substance use challenges alongside significant mental health disorders or emotional issues. The center features programs that include intensive outpatient, outpatient, and day treatment, utilizing methods such as 12-step support, anger management therapy, and brief intervention strategies. There are specialized services designed for active duty military personnel, adolescents, and adult males, providing personalized care. Emphasizing high-quality, individualized treatment, this center invites male and female clients to engage in effective rehabilitation within a nurturing atmosphere.

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Oak Lawn, IL

Situated in Oak Lawn, Illinois, Solleys Place stands as a premier facility dedicated to recovery. They provide a comprehensive suite of services, encompassing detox and addiction treatment. Their offerings include intensive outpatient, outpatient, and outpatient detox programs, designed for adults and seniors. Special considerations are given to active duty military, adult men, and adult women. Solleys Place utilizes proven methods like 12-step facilitation, brief intervention, and cognitive-behavioral therapy for thorough care. Prioritizing personalized recovery plans, this center delivers effective support to all clients, regardless of gender, aiming for successful rehabilitation.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)