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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Sobermans Estate
Cave Creek, AZ

Sobermans Estate, situated in Cave Creek, AZ, stands as a leading addiction treatment provider for adult males. This institution delivers comprehensive care through hospital inpatient services, round-the-clock inpatient hospital support, and intensive outpatient programs. Emphasizing strategies like 12-step integration, emotional regulation, and concise counseling, Sobermans Estate crafts personalized treatment plans for individuals affected by intimate partner violence, domestic abuse, and sexual trauma. Serving both adults and older adults, the center is committed to delivering excellent care within a nurturing setting. For those in pursuit of thorough addiction recovery services, Sobermans Estate is devoted to supporting individuals on their path to enduring sobriety.

Sobriety Centers of NH

Sobriety Centers of NH located in Laconia, NH, presents a wide array of treatments for substance use disorders, addressing issues of co-occurring substance use and significant mental health disorders in adults, as well as emotional challenges in children. The facility provides specialized programs tailored for active military personnel, along with men and women of various backgrounds. It offers a mix of intensive outpatient, outpatient, and partial hospitalization services, employing well-established methods such as 12-step support, anger management, and short-term interventions. Committed to providing top-notch care, Sobriety Centers of NH serves adults and young adults of all genders who are on their journey to recovery.

Sobrius Curae
Galax, VA

Sobrius Curae, situated in Galax, VA, delivers extensive outpatient treatment for substance use disorders. This center specializes in addressing the needs of those dealing with both substance abuse issues and significant mental health challenges. They provide a range of services, including outpatient day programs, partial hospitalization, and ongoing outpatient care. Utilizing evidence-based practices such as 12-step initiatives, anger management techniques, and motivational incentive strategies, Sobrius Curae is distinguished by its customized programs for active duty military members, as well as services specifically designed for adult men and women. Committed to offering top-notch care, the center supports adults and young adults of all genders on their journey to recovery.

Sobriety Solutions Lakeside

Nestled in Sicklerville, NJ, Sobriety Solutions Lakeside provides extensive care for individuals struggling with substance misuse. The center is adept at addressing dual diagnoses, treating addiction in adults while simultaneously managing significant mental health conditions, and supporting children with emotional challenges. Their commitment to excellent care is reflected in their offerings, which include intensive outpatient programs, general outpatient services, and day treatment. Sobriety Solutions Lakeside utilizes proven therapeutic methods like 12-step integration, anger resolution, and short-term counseling. Specific, customized treatment plans are offered for military members, and for both male and female adults. This facility serves all genders in their pursuit of successful recovery.

Sobriety Solutions of Pennsylvania

Sobriety Solutions of Pennsylvania, situated in Plymouth Meeting, PA, specializes in extensive treatment for substance use and offers focused support for adults grappling with significant mental health challenges or emotional issues. The center provides various programs including intensive outpatient treatment, outpatient day programs, and partial hospitalization options. Utilizing customized strategies such as 12-step programs, anger management, and short-term interventions, the facility prioritizes personalized care. Additionally, specific programs are available for active military personnel, as well as adult men and women. Aiming to assist adults and young adults of all genders, Sobriety Solutions of Pennsylvania is dedicated to providing top-notch, evidence-informed rehabilitation services to foster enduring recovery.

Social Science Services Inc

Social Science Services Inc, situated in Bloomington, CA, provides extensive rehabilitation services with a focus on treating substance abuse and co-occurring mental health issues. The facility offers multiple treatment options, including long-term and short-term residential programs, as well as 24-hour supervision. Emphasizing techniques such as 12-step programs, anger management, and cognitive behavioral therapy, the center creates personalized treatment plans that address unique needs. With specializations in trauma support and services for pregnant and postpartum women, it serves adult, senior, and young adult female clients. Social Science Services Inc is committed to delivering high-quality, gender-responsive care to aid individuals in their recovery journey.

Social Science Services Inc

Social Science Services Inc in Bloomington, CA, delivers extensive addiction recovery programs. They offer detoxification, substance abuse therapy, and targeted support for adults with dual diagnoses of substance abuse and severe mental health conditions, or children with significant emotional disturbances. Patients benefit from customized treatment plans within long-term residential, outpatient, and standard outpatient settings. The facility utilizes proven methods like 12-step integration, anger management training, and cognitive behavioral therapy. Distinct programs are available for adult males, adult females, and individuals with trauma histories. Catering to both male and female adults and young adults, this establishment is dedicated to providing effective recovery support.

Sobermind Recovery Center

Sobermind Recovery Center, located in Winnetka, CA, delivers a full range of rehabilitation services designed for those facing addiction challenges. The center features long-term residential treatment, detoxification services, and around-the-clock support for both adults and young adults. With expertise in addressing co-occurring substance use disorders alongside severe mental health conditions, the center creates customized programs that cater to the unique requirements of each client. Emphasizing a comprehensive recovery strategy, Sobermind incorporates 12-step methodologies, anger management techniques, and targeted interventions. Committed to providing top-quality care, Sobermind Recovery Center focuses on personalized treatment approaches to foster the recovery journey for both men and women.

Social Model Recovery Systems

Social Model Recovery Systems, situated in Los Angeles, California, delivers extensive support for individuals battling substance use disorders, particularly those facing co-occurring serious mental health conditions or emotional challenges. The facility offers a range of residential options, including extended, brief, and round-the-clock care. Their therapeutic methodologies incorporate 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Targeted interventions are available for adult men, women, and survivors of intimate partner or domestic violence. This center is dedicated to providing high-quality, personalized care for adult and young adult clients of all genders, fostering their journey toward recovery and well-being.

Social Recovery Center
Springfield, NJ

Social Recovery Center in Springfield, NJ, delivers tailored support for adults navigating the complexities of addiction alongside significant mental health concerns, or for children experiencing emotional distress. The center provides various levels of care, including intensive outpatient, standard outpatient, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their approach emphasizes principles of 12-step programs, strategies for managing anger, and short-term counseling techniques. This establishment is equipped to assist adult men and women, including individuals who have experienced domestic violence. Accommodating both adults and young adults of all genders, Social Recovery Center designs personalized plans to offer complete assistance and guidance to individuals pursuing healing from substance dependence and mental well-being issues.

Sojourner Recovery Services

Sojourner Recovery Services located in Hamilton, OH, provides a wide variety of treatment options for individuals dealing with substance use issues and related mental health disorders in both adults and children. The center's offerings encompass intensive outpatient programs, outpatient services, and day programs. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational incentives, they offer targeted services to active duty military members, teenagers, and adult males. Sojourner Recovery Services is dedicated to offering exceptional care tailored to the specific requirements of all adults and young people, regardless of gender, and aims to foster enduring recovery.

Social Model Recovery Systems

Social Model Recovery Systems in Covina, CA, provides extensive support for adults and young adults overcoming substance dependence. Their programs are adept at managing dual diagnoses, where substance abuse intersects with significant mental health challenges. Offering various levels of care including intensive outpatient and regular outpatient services, they deliver personalized treatment. This is achieved through methods like anger management, brief intervention, and cognitive behavioral therapy. They also specifically support adult men, adult women, and individuals with trauma histories, fostering a secure and understanding atmosphere. For those pursuing effective recovery, this center stands out as a leading option.

Sobriety Centers of NH

Sobriety Centers of NH, located in Antrim, New Hampshire, provides a wide array of addiction recovery services designed for both adults and young adults. The facility focuses on detox services, treatment for substance use disorders, and addressing dual diagnoses for those facing both addiction and significant mental health challenges. Offering 24/7 residential support and short-term programs, the center creates a nurturing atmosphere conducive to recovery. Employing methods such as 12-step programs, anger management strategies, and brief intervention techniques, treatment plans are customized to suit each individual’s requirements. The center also features specialized programs for active duty military personnel, as well as distinct services for adult men and women. Committed to delivering high-quality care, Sobriety Centers of NH aims to support clients in achieving enduring sobriety and improved mental health.

Sober Living Willowcreek

Sober Living Willowcreek, based in Sandy, UT, offers an extensive array of rehabilitation services designed for adult women on their path to recovery from substance abuse. The center provides a variety of options including intensive outpatient care, day treatment, and partial hospitalization, utilizing proven methodologies such as 12-step programs and anger management strategies. Additionally, Sober Living Willowcreek features specialized support for individuals affected by intimate partner violence and domestic abuse, fostering a nurturing and secure space for recovery. With a focus on adults, seniors, and young women, the facility is dedicated to empowering its clients to attain enduring sobriety through customized treatment and well-rounded support.

Sober Living Properties

Sober Living Properties in Sandy, UT, is dedicated to providing adults with a full spectrum of addiction recovery solutions. Our offerings encompass detox, comprehensive substance abuse treatment, and structured transitional living in a nurturing setting. We employ various therapeutic models, including intensive outpatient and day treatment programs, utilizing proven methods like 12-step facilitation and anger management techniques. Our specialized programs are designed for active military members, adult men, and those affected by intimate partner violence. Sober Living Properties is committed to delivering high-quality, individualized care for adults, seniors, and young adults on their journey to lasting sobriety.

Sober Living Properties
Salt Lake City, UT

Recovery Residence Solutions in Salt Lake City, UT delivers extensive substance abuse treatment designed for adults and the elderly. This establishment provides detox, drug and alcohol rehabilitation, supportive housing, and sober living accommodations, emphasizing intensive outpatient and daily outpatient treatment approaches. The facility excels in guiding clients through 12-step principles, managing anger, and employing brief intervention strategies to aid in their recovery process. Distinct programs are available for women, adult females, current military members, and those affected by domestic abuse. Their superior quality of care and targeted interventions position them as a premier provider for individuals pursuing successful and empathetic addiction recovery.

Sober Strategies Inc

Sober Strategies Inc, located in Urbandale, IA, provides outpatient treatment for substance use disorders aimed at both adults and youth. The center emphasizes personalized care with services that include 12-step facilitation, anger management, and brief intervention techniques. Designed to cater to the distinct needs of each individual, Sober Strategies Inc features special programs for both men and women. By integrating evidence-based methodologies with empathetic support, the facility prioritizes high-quality care to assist individuals on their path to recovery. Whether you are seeking assistance for yourself or someone else, this center fosters a nurturing atmosphere for anyone striving to conquer addiction.

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Sobriety House Inc. in Detroit, MI, is dedicated to providing tailored substance use disorder recovery for adult men, seniors, and younger individuals. They offer a range of services including intensive outpatient, extended residential stays, and standard outpatient care, all customized for each client. Utilizing methods such as 12-step facilitation, anger management, and brief intervention strategies, the center delivers thorough support. Distinctive offerings for active military members, adult males, and survivors of domestic abuse highlight their specialized approach. Sobriety House Inc. fosters a nurturing setting for individuals pursuing lasting sobriety.

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Social Model Recovery Systems, situated in El Monte, CA, stands out as a leading rehabilitation facility that focuses on detoxification and treatments for substance abuse. This center provides residential detox services and around-the-clock care specifically designed for adult men on their recovery journey. Emphasizing 12-step programs, anger management, and brief intervention strategies, the center is equipped to support active duty military members, adult males, and victims of intimate partner violence. Catering to adults, seniors, and young adults, this establishment fosters a nurturing atmosphere for male clients aiming to conquer addiction and reclaim their lives.

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Social Model Recovery Systems in El Monte, CA, provides extensive addiction treatment within a nurturing residential environment. They offer various residential program lengths for adult men struggling with addiction, including options for extended stays, shorter durations, and immediate, around-the-clock care. Their expertise lies in guiding clients through 12-step programs, anger management techniques, and cognitive behavioral therapy, specifically assisting those affected by domestic or intimate partner violence. The center also serves active duty military members, adult males, and individuals across all age groups, prioritizing personalized care and proven therapeutic methods to support successful recovery from substance dependency.

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Sojourners Recovery, located in Lake Mary, FL, delivers an extensive range of treatment options for both adults and children/adolescents facing substance use challenges alongside significant mental health disorders or emotional issues. The center features programs that include intensive outpatient, outpatient, and day treatment, utilizing methods such as 12-step support, anger management therapy, and brief intervention strategies. There are specialized services designed for active duty military personnel, adolescents, and adult males, providing personalized care. Emphasizing high-quality, individualized treatment, this center invites male and female clients to engage in effective rehabilitation within a nurturing atmosphere.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)