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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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St Johns Recovery Place
Crescent City, FL

Situated in Crescent City, FL, St Johns Recovery Place provides extensive addiction treatment options for both adults and young adults. The facility offers hospital-based inpatient detoxification alongside treatment programs emphasizing 12-step facilitation, anger management, and brief intervention strategies. St Johns Recovery Place features tailored programs for active duty military personnel, adult men, and adult women, addressing a variety of needs. Male and female patients benefit from personalized care designed to assist them on their path to recovery. The center’s dedication to delivering high-quality care and diverse treatment alternatives makes it an essential resource for anyone in need of effective rehabilitation services.

St Vincent HHS of the Third Order of

Situated in Marinette, WI, St Vincent HHS of the Third Order of provides a wide range of programs for substance use rehabilitation. The center features intensive outpatient care, general outpatient services, and treatment alternatives involving methadone/buprenorphine or naltrexone. Employing strategies like 12-step support, brief interventions, and cognitive behavioral therapy, the facility customizes treatment plans for each client. Catering to both adults and children/adolescents, and offering services to male and female individuals alike, St Vincent HHS of the Third Order of focuses on providing tailored support for everyone. This center is noted for its dedication to providing exceptional, individualized addiction treatment.

Stages of Recovery Inc

Stages of Recovery Inc in Lubbock, TX provides extensive treatment for substance use issues, catering to both adults and children who also face mental health challenges. The center offers various programs, including intensive outpatient, outpatient, and day treatment, and emphasizes methods such as 12-step support, anger management, and concise intervention strategies. There are specialized offerings for active military members, adult men, and survivors of intimate partner violence. With a commitment to individualized care for all clients, regardless of gender, the center strives to deliver effective rehabilitation services in a nurturing setting, helping individuals navigate their recovery journey.

Stages of Recovery Inc

Situated in Waco, TX, Stages of Recovery Inc provides targeted treatment for adults facing substance use challenges alongside significant mental health disorders, as well as emotional issues in children. The center features a range of treatment options including intensive outpatient, outpatient, and day programs, utilizing methods such as 12-step support, anger management, and brief intervention strategies. It offers specialized programs for military personnel, adult males, survivors of intimate partner violence, and other domestic violence victims, catering to individuals of all ages and genders. Stages of Recovery Inc emphasizes personalized care plans and evidence-supported techniques to assist clients in their recovery process.

Stairway Resource Center
Woodland Hills, CA

Situated in Woodland Hills, CA, the Stairway Resource Center delivers a wide range of rehabilitation services aimed at adults and young adults facing challenges related to substance use and concurrent mental health conditions. The center specializes in intensive outpatient programs, outpatient day treatment, and partial hospitalization. Emphasizing approaches such as 12-step facilitation, anger management, and brief intervention, the center serves both men and women, including those who have encountered intimate partner violence. Stairway Resource Center is committed to offering exceptional care that is customized to the specific needs of each client, facilitating a supportive and successful recovery experience.

Starlite Recovery Center
Center Point, TX

At Starlite Recovery Center in Center Point, TX, adults and young adults can access a complete spectrum of addiction care. The center delivers detox, substance abuse treatment, and dedicated support for dual diagnoses involving serious mental health or emotional conditions. Offering diverse pathways like intensive outpatient, extended residential stays, and outpatient services, Starlite Recovery Center adapts to individual requirements. Their recovery model incorporates 12-step guidance, anger management techniques, and targeted interventions, fostering a tailored and successful path to sobriety. Specific programs are also provided for active military personnel, adult men, and adult women. Starlite Recovery Center is committed to delivering superior support for those pursuing freedom from addiction.

Start Fresh Treatment Center

Start Fresh Treatment Center in Asheville, NC, provides comprehensive outpatient substance use disorder care for adults. Their services extend to individuals facing co-occurring mental health conditions or emotional disorders. The center offers medication-assisted treatment options including methadone, buprenorphine, and naltrexone, alongside robust relapse prevention strategies and remote therapy services. Catering to a diverse clientele of adults and young adults, regardless of gender, Start Fresh Treatment Center is dedicated to personalized treatment plans and ensuring high-quality support for those navigating addiction and mental wellness.

Start Fresh Treatment Center

At Start Fresh Treatment Center in Supply, NC, we provide complete outpatient care for individuals grappling with substance use disorders. Our expertise extends to addressing co-occurring mental health challenges in adults and emotional difficulties in young people. We are dedicated to crafting personalized recovery plans that prioritize preventing relapse. Offering medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside accessible telehealth services, Start Fresh Treatment Center makes quality support readily available. Our programs are designed to meet the unique needs of all clients, promoting a bespoke journey toward wellness and sustained recovery.

State Line Treatment Services

State Line Treatment Services in Harrison, OH, delivers a full spectrum of care for individuals battling addiction. Their offerings include intensive outpatient, standard outpatient, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The center employs evidence-based therapeutic modalities such as anger management, cognitive behavioral therapy, and motivational interviewing to create personalized recovery plans. They also provide distinct programs designed for adult men and women, alongside specialized support for those managing co-occurring mental health and substance use challenges. State Line Treatment Services is dedicated to providing equitable and effective rehabilitation for all clients.

St Lawrence County Comm Servs Board

St. Lawrence County Comm Servs Board in Canton, NY, delivers thorough substance abuse recovery services designed for adult men, adult women, and individuals facing dual diagnoses of mental health and substance use challenges. The facility features intensive outpatient care, standard outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Utilizing specialized therapeutic methods such as anger management, cognitive behavioral therapy, and the Matrix Model, this establishment guarantees personalized support for adults and older adults. By providing gender-specific programming, St. Lawrence County Comm Servs Board is committed to high-quality care and successful treatment interventions to guide people toward lasting sobriety.

Stable Community Services

Stable Community Services located in Burlington, NJ, provides an extensive selection of treatment options for those facing challenges with substance abuse and related mental health issues. This center features intensive outpatient programs, standard outpatient services, and specialized pathways for individuals experiencing co-occurring disorders. Emphasizing methods such as 12-step support, anger management strategies, and cognitive behavioral therapy, the facility customizes its approach to fit the diverse requirements of both adults and youth. Additionally, it offers transitional housing and sober living arrangements, fostering a nurturing atmosphere for clients of all genders who are committed to recovery. With a dedication to high-quality treatment, Stable Community Services emerges as a reliable option for individuals embarking on their healing journey.

Stafford Family Services
Stafford Springs, CT

Located in Stafford Springs, CT, Stafford Family Services specializes in outpatient care for adults facing substance use and dual mental health conditions, as well as emotional challenges in children. This center adopts various therapeutic methods, including motivational interviewing, anger management, and personalized counseling for substance use disorders. With programs designed for adults and seniors of all genders, Stafford Family Services is recognized for its holistic approach and commitment to high-quality care. Those looking for assistance with substance use or mental health issues can anticipate receiving compassionate and impactful support at this center.

START Treatment and Recovery Centers

START Treatment and Recovery Centers, located in New York, NY, delivers focused outpatient programs for substance use treatment aimed at both adults and young adults. The center employs proven strategies, including brief interventions, cognitive behavioral therapy, and motivational interviewing, to ensure customized support for individuals on the path to recovery. With an emphasis on inclusivity, START features dedicated programs for adult men and women, as well as clients who have faced incidents of intimate partner or domestic violence. Moreover, the center offers outpatient treatment options using methadone, buprenorphine, or naltrexone, fostering a well-rounded and supportive atmosphere for clients striving for sobriety.

Starting Point Behavioral Healthcare

Starting Point Behavioral Healthcare, located in Yulee, FL, delivers extensive outpatient treatment for adults facing substance use challenges alongside significant mental health conditions. The facility features targeted therapies, including anger management, cognitive behavioral therapy, and short-term intervention strategies. It also provides unique programs designed for adolescents, adult women, and individuals who have undergone sexual trauma. Catering to both adults and seniors, regardless of gender, the center offers outpatient options for methadone, buprenorphine, or naltrexone therapy. With its commitment to high-quality care and personalized treatment plans, it stands out as an excellent resource for those in need of effective rehabilitation support in the Yulee region.

Stairways Drug and Alcohol

Stairways Drug and Alcohol, situated in Erie, PA, stands as a premier provider of addiction treatment services. The facility delivers specialized care through intensive outpatient, standard outpatient, and medication-assisted treatment options, including methadone, buprenorphine, or naltrexone. Prioritizing long-term recovery, their services encompass relapse prevention strategies, counseling for substance use disorders, and support for trauma survivors. Stairways Drug and Alcohol is equipped to assist adult men and women, as well as young adults, offering tailored and all-encompassing support for those seeking to overcome addiction. Their dedication to high-quality care is central to their mission of fostering enduring sobriety.

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Fall River, MA

SSTAR, situated in Fall River, MA, specializes in a variety of evidence-supported therapies for individuals dealing with substance use issues and related mental health challenges, catering to both adults and children. The facility offers intensive outpatient, outpatient, and day treatment services, utilizing methods such as 12-step support, anger management, and brief intervention techniques. Additionally, it features tailored programs for those who have faced intimate partner violence, domestic abuse, sexual trauma, and other forms of adversity. Serving individuals of all genders, SSTAR prioritizes customized care and guidance to facilitate meaningful recovery. Known for its commitment to quality and all-encompassing services, this center is recognized as a reliable option for those in pursuit of effective rehabilitation solutions.

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Fall River, MA

SSTAR in Fall River, MA, provides extensive addiction care for individuals and adolescents grappling with substance abuse and psychological well-being issues. The facility offers diverse treatment options, including inpatient detox, round-the-clock residential stays, and brief residential stays. SSTAR customizes its methods for men, women, and those with dual diagnoses, ensuring personalized support. Employing proven therapeutic strategies like 12-step support, cognitive behavioral therapy, and concise counseling, the center delivers excellent treatment for all clients pursuing sobriety.

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The St. Kolbe Puckett Center for Healing, situated in Saint Joseph, MO, stands as a premier institution dedicated to the treatment of substance use disorders. They provide diverse therapeutic options including outpatient services, methadone/buprenorphine or naltrexone treatment within an outpatient setting, and standard outpatient care. This facility is committed to delivering personalized support for adults and young adults. Recognizing the unique challenges faced by specific groups, they offer specialized programs designed for active duty military, adult men, and adult women. Employing scientifically validated methodologies such as 12-step facilitation, brief intervention, and motivational interviewing, the center ensures effective and individualized care. Serving both male and female individuals, the St. Kolbe Puckett Center for Healing is a steadfast partner in the recovery process.

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St Mary Behavioral Health Center, situated in Morgan City, LA, delivers thorough care for substance use disorders and co-occurring mental health conditions. This establishment provides outpatient programs, encompassing methadone and buprenorphine treatment, designed for adults experiencing significant emotional distress and mental health challenges. The center's expertise lies in areas such as anger management, brief intervention strategies, and cognitive behavioral therapy. Offering customized services for young people, adult men, and women, St Mary Behavioral Health Center supports individuals across the lifespan, including seniors, of all genders. Clients will find personalized treatment plans and scientifically validated methods aimed at fostering their path to recovery.

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Stages of Recovery Inc in Abilene, TX, delivers an extensive array of evidence-informed therapies for addressing substance use disorders and concurrent mental health issues in both adults and children. The center features specialized services for active military members, men, and individuals who have experienced domestic abuse, ensuring that the care provided is customized to meet varied requirements. Their outpatient services, which encompass treatments such as methadone and buprenorphine, serve both adults and youths. By employing methods including 12-step programs and anger management techniques, the facility aims to promote a well-rounded recovery process. Stages of Recovery Inc is committed to high standards of care, supported by a collaborative team focused on helping clients achieve enduring sobriety and enhanced mental health.

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Starting Point Behavioral Healthcare, located in Fernandina Beach, FL, provides extensive outpatient services for both substance use and co-occurring mental health issues in children and adults. This center offers targeted programs for teenagers, women, and individuals who have faced sexual trauma. Emphasizing methods such as anger management, brief interventions, and cognitive behavioral therapy, they deliver personalized treatment to adults and seniors across all genders. The facility provides outpatient options including methadone/buprenorphine or naltrexone treatment, alongside regular outpatient programs, ensuring a comprehensive recovery strategy. Patients can anticipate high-quality, individualized support that meets their specific requirements at Starting Point Behavioral Healthcare.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)