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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Stepworks of Elizabethtown

Situated in Elizabethtown, KY, Stepworks of Elizabethtown delivers thorough addiction recovery plans for adults and adolescents. This institution features extended stay housing, onsite detox services, and round-the-clock residential support. Stepworks extends tailored therapy for concurrent addiction and severe mental health conditions in adults, or significant emotional challenges in youth. Emphasizing 12-step encouragement, emotional regulation training, and short-term intervention strategies, the facility serves adult males and females, along with individuals with a history of sexual trauma. Dedicated to high-standard support, Stepworks of Elizabethtown stands as a crucial provider of impactful and nurturing recovery solutions.

Stepworks Recovery Centers

Stepworks Recovery Centers, located in London, KY, delivers extensive addiction recovery services tailored for adult men in need of long-term residential support. This center excels in detox services, addressing substance use disorders, and providing treatment for individuals facing both substance use and severe mental health challenges. Emphasizing personalized treatment, Stepworks Recovery Centers incorporates 12-step programs, anger management, and brief intervention strategies. Additionally, specialized programs are available for clients who have endured sexual trauma or abuse. The residential care, available 24/7, is suitable for seniors, adults, and young adults alike. With a strong dedication to high-quality care, this center stands out as an exceptional option for those in search of effective rehabilitation assistance.

Stonegate Center

Stonegate Center, located in Azle, Texas, delivers extensive care for individuals struggling with addiction. The center provides hospital-based inpatient detox and treatment for various dependencies, as well as mental health conditions and significant emotional challenges in youth. Their approach integrates 12-step facilitation, anger management techniques, and brief intervention strategies. Stonegate Center serves adult men, adult women, and individuals experiencing both mental health and substance use issues concurrently. Emphasizing high-standard treatment, the center features specialized offerings designed to meet each person's distinct requirements. For those needing support with substance dependency or dual diagnoses, Stonegate Center offers a nurturing setting conducive to recovery and wellness.

Stepworks of Bowling Green

Stepworks of Bowling Green, situated in Bowling Green, KY, delivers extensive addiction rehabilitation for adults and adolescents. The facility excels in extended residential stays, inpatient detox, and round-the-clock residential treatment. Employing strategies like 12-step support, emotional regulation training, and short-term intervention methods, Stepworks serves those with co-occurring mental health disorders and substance dependencies. Distinctive offerings include customized support for men, women, and survivors of sexual trauma. By offering distinct care pathways for male and female patients, Stepworks of Bowling Green guarantees effective, individualized treatment to foster lasting recovery.

Stillaguamish Tribe
Arlington, WA

Situated in Arlington, WA, the Stillaguamish Tribe rehabilitation center provides comprehensive outpatient programs, including intensive outpatient treatment and medication-assisted therapies such as methadone, buprenorphine, or naltrexone for those struggling with substance use. This facility emphasizes 12-step support, anger management techniques, and short-term intervention strategies, serving both adults and young adults regardless of gender. With a particular emphasis on individuals who have faced trauma, the center ensures personalized care and assistance. The Stillaguamish Tribe center is dedicated to offering effective, research-supported treatment to support individuals in their journey toward recovery from addiction.

Stony Brook Eastern Long Island Hosp

Situated in Greenport, NY, Stony Brook Eastern Long Island Hosp delivers thorough addiction rehabilitation services for both adults and young adults. This establishment features hospital inpatient detox services and treatment programs for substance use disorders that also address concurrent mental health challenges. The center offers tailored programs for adult men and women, along with support for clients with dual diagnoses, focusing on personalized care to meet individual needs. By integrating 12-step facilitation, anger management, and brief interventions, the center promotes a comprehensive path to recovery. The exceptional care provided here supports individuals in achieving sustained sobriety and emotional stability, establishing it as a respected option for those in need of effective treatment.

Stepworks Crowne Pointe
Elizabethtown, KY

Stepworks Crowne Pointe in Elizabethtown, KY, delivers a full spectrum of addiction recovery support for adults and younger individuals. Their services encompass drug and alcohol detoxification, therapeutic interventions for substance abuse, and tailored programs addressing dual diagnoses of substance use disorders and severe mental health conditions. Stepworks Crowne Pointe offers flexible treatment options such as intensive outpatient, standard outpatient, and partial hospitalization programs to accommodate diverse recovery journeys. Key therapeutic modalities employed include 12-step program integration, anger management strategies, and brief intervention techniques. Additionally, specialized support groups are provided for adult men, women, and survivors of sexual trauma. This establishment is dedicated to providing high-quality, impactful recovery services.

Stepworks of Nicholasville

Situated in Nicholasville, KY, Stepworks of Nicholasville delivers a wide range of addiction recovery services for both adults and young individuals. The center is adept at handling detoxification, substance abuse treatment, and mental health issues arising simultaneously. Prioritizing exceptional care, Stepworks offers inpatient detox and treatment with around-the-clock support. The facility employs diverse methods including 12-step programs, anger management, and short interventions to customize care for each person. Additionally, Stepworks of Nicholasville features tailored programs specifically for adult women, those who have undergone sexual trauma, and individuals dealing with past traumatic experiences. With a welcoming atmosphere for both men and women, this center supports individuals on their journey to recovery.

Stepworks of Nicholasville

Stepworks of Nicholasville in Nicholasville, KY, delivers extensive addiction treatment and expert support for those battling co-occurring substance use and severe mental health challenges. The center features outpatient options, such as day treatment, partial hospitalization, and medication-assisted treatment. Emphasizing 12-step approaches, anger management, and concise interventions, Stepworks supports adult men and women, including survivors of sexual abuse. Their offerings extend to young adults, with gender-specific programming. Stepworks is a reliable destination for individuals pursuing lasting recovery due to its dedication to high-quality, personalized care.

Stoneridge Centers for
Prescott Valley, AZ

Prescott Valley's Stoneridge Centers delivers complete care for addiction and dual diagnoses in adults and children facing mental health challenges. Their programs, including intensive outpatient, outpatient, and day treatment, integrate 12-step facilitation, brief intervention, and cognitive behavioral therapy. Specialized tracks are available for adult men, adult women, and survivors of intimate partner violence. Serving all genders, Stoneridge Centers emphasizes personalized, evidence-based treatment for sustained well-being.

Stewards of Recovery
Idaho Falls, ID

Stewards of Recovery, situated in Idaho Falls, ID, delivers complete addiction recovery services for adults and young adults. Their program offerings include intensive outpatient, outpatient, and partial hospitalization. Employing proven therapeutic methods like cognitive behavioral therapy, community reinforcement with incentives, and the Matrix Model, the center personalizes care for each individual. Specialized support is available for active military personnel, teenagers, and adult men, providing focused recovery pathways. Accommodating both male and female patients, Stewards of Recovery provides excellent, gender-tailored addiction care within a nurturing atmosphere.

Stigler Health and Wellness Center

Stigler Health and Wellness Center, situated in Poteau, OK, delivers a full spectrum of addiction recovery services. Their offerings include structured intensive outpatient care, extended stay residential programs, and standard outpatient support for adult men, adult women, and individuals within the criminal justice system. Employing approaches like brief intervention, cognitive behavioral therapy, and the Matrix Model, the facility customizes treatment plans. Catering to adults and seniors across all genders, Stigler Health and Wellness Center prioritizes excellent care within a nurturing setting. For those seeking impactful and individualized addiction recovery, this center is committed to guiding individuals toward sustained sobriety.

Stonington Institute

Stonington Institute, located in Groton, CT, provides a variety of evidence-supported treatment options for individuals dealing with substance abuse and concurrent mental health issues, applicable to both adults and children. The facility offers intensive outpatient services, standard outpatient programs, and day treatment sessions, utilizing methods such as 12-step support, anger management strategies, and brief intervention techniques. Tailored programs are available for adult men and women, as well as clients with trauma histories, addressing a wide array of needs. Known for its holistic and personalized approach, Stonington Institute serves individuals of all genders, focusing on delivering effective care to assist in their recovery processes.

Sterling Area Health Center

Situated in Sterling, MI, Sterling Area Health Center delivers extensive treatment for substance use aimed at adults and seniors. The facility specializes in outpatient care, emphasizing 12-step facilitation, anger management, and brief intervention strategies. A distinguishing feature of this center is its personalized treatment plans designed to meet the individual needs of each client. Offering quality support, the center caters to both men and women. Whether clients are pursuing routine outpatient treatment or specific services, Sterling Area Health Center is committed to aiding individuals in their journey to conquer addiction and attain lasting recovery.

Steward St Elizabeths/SECAP/ATS

Steward St Elizabeths/SECAP/ATS, situated in Brighton, MA, delivers a wide range of addiction recovery services. The center features hospital-based inpatient detox, around-the-clock inpatient care, and intensive outpatient programs tailored for both adults and young adults. It emphasizes techniques such as motivational interviewing, relapse prevention strategies, and counseling specifically for substance use disorders. Special programs are designed for adult males, adult females, and women who are pregnant or in the postpartum stage. Committed to personalized care, this facility fosters a nurturing atmosphere for individuals of all genders striving for recovery from substance use challenges.

Stigler Health and Wellness Center

Situated in Stigler, OK, the Stigler Health and Wellness Center provides extensive outpatient services for individuals dealing with substance abuse and concurrent mental health issues, serving both adults and children. Their targeted programs are designed for adolescents as well as adult men and women, ensuring that each service is customized to address the specific requirements of every patient. The center employs research-backed methods, such as cognitive behavioral therapy and the Matrix Model, to deliver high-quality care to adults and seniors from all backgrounds. Whether patients are looking for outpatient methadone/buprenorphine options or standard outpatient care, they can anticipate a supportive and effective treatment experience at this facility.

Stigler Health and Wellness Inc

Stigler Health and Wellness Inc, located in McAlester, OK, delivers a full spectrum of addiction recovery care designed for adults and older adults. Their offerings include detox services, treatment for substance use disorders, transitional accommodations, and sober living environments. Patients can choose from intensive outpatient, extended residential, and standard outpatient treatment modalities. Employing strategies like brief intervention, cognitive behavioral therapy, and community reinforcement with incentives, the center customizes its approach to meet unique client requirements. They also provide specialized programs for young people, adult men, and adult women. Stigler Health and Wellness Inc is committed to high-quality care through tailored treatment specifically for males and females.

Stonington Institute
North Stonington, CT

Situated in North Stonington, CT, Stonington Institute delivers a range of rehabilitation services for both adults and young adults. The center is dedicated to detoxification, treating substance use disorders, and addressing dual diagnoses for those facing concurrent substance use and significant mental health challenges. Treatment offerings encompass residential detox programs, round-the-clock residential support, and short-term residential options. Stonington Institute employs customized strategies including 12-step programs, anger management courses, and brief therapeutic interventions. Additionally, specialized programs are designed for active-duty service members, as well as adult men and women. Committed to personalized care and the use of evidence-based methods, this facility provides exceptional treatment for individuals of all genders who are pursuing addiction recovery.

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Situated in Blackfoot, ID, "Stewards of Recovery" delivers extensive treatment services for both adults and young adults grappling with addiction. The center features long-term residential care, detoxification programs, and round-the-clock support for residents. Emphasizing a 12-step approach, it also incorporates anger management and cognitive behavioral therapy, specifically designed for those facing dual challenges of substance abuse and severe mental health issues. With a focus on addressing intimate partner and domestic violence, "Stewards of Recovery" provides customized programs catering to the needs of adult men and women. Committed to excellence in care, the facility aims to lead individuals on their journey to sustainable recovery.

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The Stigler Health and Wellness Center in Wilburton, OK, offers a wide range of treatment options for individuals grappling with substance use disorders and related mental health challenges, catering to both adults and children experiencing significant emotional difficulties. The center provides outpatient services that include treatments such as methadone/buprenorphine or naltrexone, alongside standard outpatient programs. Emphasizing practical interventions, cognitive behavioral therapy, and the Matrix Model, this facility creates customized treatment strategies suitable for adolescents, men, and women. Committed to delivering excellent care, the center supports adults and seniors from diverse backgrounds on their journey to recovery.

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Situated in Eufaula, OK, Stigler Health and Wellness Center provides all-encompassing addiction recovery services designed for each person's unique journey. The center offers adaptable treatment plans, including intensive outpatient, standard outpatient, and general outpatient programs. Through the use of telemedicine and virtual therapy, the facility guarantees support is accessible from any location. Tailored interventions are available for teenagers, adult males, and adult females, serving a diverse age range from seniors to young adults. Catering to both male and female clients, the center cultivates a nurturing atmosphere for everyone. Discover excellent support and individualized recovery at Stigler Health and Wellness Center.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)