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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Summit Wellness Group

Summit Wellness Group located in Roswell, GA, specializes in providing extensive addiction treatment and transitional living services. This center is designed to support adults dealing with substance use disorders and significant mental health challenges. The range of treatment services includes intensive outpatient programs, day treatment options, and support through 12-step facilitation. By incorporating anger management and trauma-informed methodologies, this facility serves adult men, women, and young adults. The program prioritizes short-term interventions, ensuring tailored and effective assistance for each client. Summit Wellness Group is committed to offering exceptional, gender-sensitive care aimed at fostering lasting recovery.

Summit Wellness Group

Summit Wellness Group, located in Atlanta, GA, provides a diverse array of rehabilitation programs designed for those aiming to overcome substance use disorders and concurrent mental health issues. The center offers intensive outpatient programs, day treatment options, and partial hospitalization. Their treatment approach incorporates 12-step support, anger management techniques, and brief intervention methods. Summit Wellness Group also includes tailored programs for adult men and women, along with support for those who have faced intimate partner or domestic violence. Focused on both adults and young adults, the facility serves individuals of all genders. Experience individualized attention and effective, research-supported treatment methods at Summit Wellness Group.

SunCloud Health SC
Northbrook, IL

SunCloud Health SC, located in Northbrook, IL, provides expert treatment for substance use disorders and co-occurring mental health issues for both adults facing severe psychological challenges and children experiencing significant emotional disturbances. The center offers a variety of programs, including intensive outpatient services, day treatment options, and partial hospitalization. Employing a range of therapeutic techniques such as 12-step programs, anger management, and cognitive behavioral therapy, SunCloud Health SC serves a diverse clientele, including active military personnel, adolescents, and adult males. The facility prioritizes tailored care for individuals of all ages and genders, aiming to fulfill the distinct requirements of each client and ensuring high standards of care and support for those on their path to recovery.

SunCloud Health SC
Naperville, IL

SunCloud Health SC, located in Naperville, IL, specializes in a wide range of rehabilitation services for both adults and children facing challenges related to substance use and co-existing mental health conditions. The center offers various treatment options, including intensive outpatient programs, day treatment services, and partial hospitalization. Emphasizing methodologies such as 12-step support, anger management, and cognitive behavioral therapy, SunCloud Health SC customizes its treatment strategies to address the unique requirements of each individual. Additionally, there are specialized programs designed for active duty military members, teenagers, and adult males. This facility caters to both men and women, providing essential care and guidance for individuals on their journey toward recovery.

SunCloud Health SC

SunCloud Health SC, located in Chicago, IL, provides a full spectrum of care for adults facing substance use challenges alongside significant mental health disorders, as well as for children experiencing severe emotional issues. The center offers various treatment modalities, including intensive outpatient, outpatient, and day treatment programs, with an emphasis on techniques such as 12-step support, anger management, and cognitive behavioral therapy. Additionally, SunCloud Health SC features specialized programs designed for active military personnel, adolescents, and adult males, addressing the needs of a diverse clientele. By offering customized services that cater to different genders and age brackets, the center ensures that each individual receives the attention they need. SunCloud Health SC is dedicated to providing effective, evidence-based treatment within a compassionate and supportive atmosphere.

Sundown M Ranch
Yakima, WA

Sundown M Ranch, situated in Yakima, WA, provides a wide range of addiction treatment services for both adults and teenagers. The center features detox programs, intensive outpatient care, standard outpatient services, and 12-step support options. Emphasizing cognitive behavioral therapy and contingency management, Sundown M Ranch serves adult males, adult females, and youth. Its specialized approaches are designed to meet the distinct requirements of each demographic, guaranteeing personalized support for all clients. Committed to delivering effective, evidence-supported treatment, Sundown M Ranch aims to assist individuals on their path to recovery.

Summit Womens Recovery

Summit Women's Recovery, situated in Dillon, CO, is dedicated to providing focused treatment for adult women facing substance use and related mental health challenges. The center offers a range of outpatient services, including intensive and regular programs, applying proven methods like cognitive behavioral therapy and contingency management. Designed to accommodate the unique needs of specific groups, such as active military members, victims of intimate partner violence, and women requiring thorough care, this facility is committed to delivering quality rehabilitation for adults and seniors. Its emphasis on gender-specific treatment positions Summit Women's Recovery as a crucial support system for women seeking tailored and effective assistance in their recovery process.

Suncoast Center Inc
Saint Petersburg, FL

Suncoast Center Inc, located in Saint Petersburg, FL, provides outpatient substance abuse services for adults, with a focus on individuals experiencing co-occurring serious mental health conditions. The center features dedicated programs tailored for active military members, young people, and adult males. Therapies employed include anger management, cognitive behavioral therapy, and motivational incentives. This establishment offers outpatient treatment utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Serving a diverse population of adults and older adults, regardless of gender, Suncoast Center Inc is committed to delivering excellent, personalized rehabilitation services in the Saint Petersburg region.

Suncoast Center Inc
Saint Petersburg, FL

Suncoast Center Inc, situated in Saint Petersburg, FL, delivers outpatient care for adults battling substance use disorders, including individuals managing co-occurring severe mental health conditions. The center excels in anger management techniques, cognitive behavioral therapy, and motivational incentives, offering proficient support across diverse age demographics, including the elderly. With customized treatment plans designed for active military personnel, teenagers, and adult men, Suncoast Center Inc prioritizes personalized healing. Accommodating both male and female patients, this organization is committed to assisting people in conquering addiction and mental health struggles through a nurturing and successful outpatient approach.

Sun Street Centers
King City, CA

Situated in King City, CA, Sun Street Centers provides a wide range of addiction treatment services within a nurturing atmosphere. The center offers multiple types of care, including detox services, substance use therapy, transitional living arrangements, and options for sober living. Emphasizing long-term residential support and around-the-clock assistance, the facility employs methods such as 12-step programs, anger management, and cognitive behavioral therapy. Sun Street Centers serves adult men and women, along with individuals who have faced sexual trauma. Catering to both adults and young adults, this center delivers personalized care that meets the unique needs of each individual pursuing recovery.

Sun Street Centers
King City, CA

Sun Street Centers in King City, CA, presents an extensive array of programs for substance use rehabilitation. The center features intensive outpatient care, standard outpatient services, and regular outpatient options customized to meet the specific needs of individuals. Employing proven methods like 12-step support, anger management strategies, and cognitive behavioral therapy, the facility serves adult men and women, including those who have faced sexual trauma. With dedicated programs for adults, children, adolescents, and young adults of all genders, Sun Street Centers prioritizes individualized support for every client. The center's dedication to high-quality treatment and its variety of services make it an essential resource for individuals in need of rehabilitation.

Sun Street Centers

Situated in Salinas, California, Sun Street Centers delivers extensive substance abuse rehabilitation services for both adults and young adults. The center features a variety of programs such as intensive outpatient, outpatient, and standard outpatient treatment options. Care is customized through methods like 12-step facilitation, anger management strategies, and cognitive behavioral therapy. Notably, Sun Street Centers provides targeted programs for men, women, and survivors of sexual abuse. With gender-focused treatment available for both sexes, this center is dedicated to offering exceptional care and assistance to those pursuing successful recovery in a friendly atmosphere.

Sun Street Centers

Sun Street Centers, situated in Salinas, CA, delivers targeted substance abuse recovery services for adult males struggling with addiction. This establishment features extensive residential treatment options, encompassing detox services and continuous oversight. Their therapeutic strategies integrate 12-step principles, emotional regulation techniques, and cognitive restructuring to foster healing. Sun Street Centers is distinguished by its dedication to serving adult males, individuals with histories of sexual trauma, and its individualized pathways for older adults and younger clients. By offering a dedicated space for men's recovery, this center ensures high standards of support and care for those committed to achieving sobriety.

SummitStone Health Partners

SummitStone Health Partners, located in Fort Collins, CO, provides a wide array of outpatient services aimed at addressing substance use disorders and accompanying mental health challenges in both adults and children. The center employs research-backed methods such as cognitive behavioral therapy and counseling specifically for substance use. By offering specialized programs for youth and gender-specific treatment for adult men and women, it ensures personalized care. Furthermore, with options like telehealth therapy and outpatient treatments utilizing methadone or buprenorphine and naltrexone, SummitStone Health Partners aims to deliver accessible and effective support to adults and seniors striving for recovery and improved mental health.

Sun Street Centers

Sun Street Centers, located in Salinas, CA, provides thorough substance abuse treatment for both adults and young adults. The facility features intensive outpatient programs, outpatient services, and standard outpatient treatment options. It emphasizes 12-step facilitation, anger management techniques, and cognitive behavioral therapy. The center offers specialized programs for adult men, adult women, and those who have faced sexual trauma. By prioritizing personalized care, Sun Street Centers delivers effective treatment for all clients pursuing recovery from substance use issues.

SummitStone Health Partners

Situated in Loveland, CO, SummitStone Health Partners delivers focused rehabilitation services geared towards adults and seniors struggling with substance use disorders. The center features a range of treatment options, including intensive outpatient programs, outpatient day therapy, and partial hospitalization. Emphasizing techniques such as 12-step facilitation, anger management, and brief intervention, SummitStone Health Partners addresses the needs of adult men, women, and adolescents who are also facing concurrent mental health challenges. Customized programs for both genders provide personalized attention, making it an ideal choice for individuals seeking thorough and supportive treatment. This facility is recognized for its dedication to providing high-quality care.

Sun Street Centers

In Marina, California, Sun Street Centers provides comprehensive substance use disorder care, encompassing intensive outpatient, standard outpatient, and regular outpatient treatment options. Their expertise lies in employing 12-step facilitation, anger management techniques, and cognitive behavioral therapy. The center features specialized programs designed for adult men, adult women, and survivors of sexual abuse. Sun Street Centers welcomes adults and young adults of all genders, fostering a healing atmosphere for those pursuing lasting recovery. Their commitment to high-quality, individualized treatment plans is central to their mission of aiding individuals in achieving sobriety.

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SummitStone Health Partners, located in Loveland, Colorado, delivers an extensive range of substance abuse treatment options through its various outpatient services. This includes outpatient programs featuring methadone, buprenorphine, or naltrexone therapy, as well as standard outpatient care. The center emphasizes tailored treatment methods such as anger management, brief interventions, and cognitive behavioral therapy. There are specialized services designed for individuals affected by intimate partner violence and domestic violence, as well as those living with HIV/AIDS and concurrent mental health and substance use disorders. SummitStone Health Partners is dedicated to providing high-quality support and care for adults and seniors of all genders who are pursuing recovery from addiction.

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Spokane, WA

Situated in Spokane, WA, Sun Ray Court is an esteemed rehabilitation facility dedicated to assisting adult men with substance use disorders. The center provides a range of programs, including long-term, short-term, and residential options available around the clock, all designed to foster a nurturing atmosphere conducive to recovery. Emphasizing the 12-step methodology, anger management, and various brief intervention strategies, Sun Ray Court customizes its offerings to cater to the unique needs of each client. It also features specialized programs for active duty military members, adult males, and individuals who have faced intimate partner violence, distinguishing it from other centers. Serving a diverse clientele that includes adults, seniors, and young adults, this facility is committed to delivering thorough care for those pursuing sobriety and overall well-being.

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Located in Seaside, CA, Sun Street Centers provides a wide range of treatment options for individuals struggling with substance use, catering to both adults and children/adolescents. Their offerings encompass intensive outpatient programs, outpatient services, and standard outpatient care. The center emphasizes therapeutic techniques such as 12-step facilitation, anger management, and cognitive behavioral therapy. With an emphasis on personalized treatment, Sun Street Centers features tailored programs for men, women, and individuals who have faced sexual abuse. By welcoming clients of all genders, they create a nurturing and inclusive atmosphere. For those in need of reliable and empathetic addiction treatment, this facility is distinguished by its varied approaches and dedication to high-quality care.

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Hollister, CA

Situated in Hollister, CA, Sun Street Centers delivers targeted rehabilitation services aimed at adult women facing issues related to substance abuse. This center features long-term residential treatment options, detoxification services, and round-the-clock care. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and anger management, Sun Street Centers supports individuals dealing with trauma and sexual abuse. The facility accommodates a range of age groups, serving not only adults but also young adults and seniors. With an emphasis on women's unique needs, this center fosters a compassionate and supportive atmosphere for recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)