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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Walker Center
Gooding, ID

Situated in Gooding, ID, the Walker Center delivers an extensive array of rehabilitation services tailored for both adults and young adults. The facility is particularly focused on detoxification and treatment for substance use disorders, offering long-term residential support and emphasizing 12-step methods and anger management strategies. It also accommodates those facing both substance use issues and significant mental health challenges. Specialized programs are available for active military members, as well as for adult men and women. Committed to providing high-quality care, the Walker Center seeks to assist individuals as they progress on their path to recovery.

Warner Park Recovery Center
Woodland Hills, CA

Warner Park Recovery Center, situated in Woodland Hills, CA, delivers targeted treatment for individuals grappling with addiction and concurrent severe mental health challenges, serving both adults and adolescents. The center offers a spectrum of care, including intensive outpatient, outpatient, and partial hospitalization programs. Core therapeutic modalities employed at the facility encompass 12-step facilitation, anger management strategies, and brief intervention techniques. Specialized programming is available for active military personnel, adult men, and women, reflecting a commitment to diverse client needs. Warner Park Recovery Center is dedicated to providing comprehensive and individualized care to assist clients in achieving lasting recovery, welcoming adults and young adults of all gender identities.

Wasatch Crest Treatment Services

Based in Heber City, UT, Wasatch Crest Treatment Services delivers extensive addiction rehabilitation options for both adults and young adults. The center features a comprehensive array of services such as detox programs, substance abuse treatment, and targeted support for individuals dealing with both substance use disorders and significant mental health challenges in adults, as well as serious emotional issues in children. Treatment modalities offered include intensive outpatient care, long-term residential stays, and outpatient services to meet diverse requirements. The center employs strategies like 12-step programs, anger management techniques, and brief interventions to ensure individualized treatment plans. Additionally, specialized programs are designed for active military personnel, as well as for adult men and women. The facility is inclusive, welcoming male and female clients, and is dedicated to providing high-quality, customized care.

Wasatch Crest Womens Residential

Nestled in Park City, UT, Wasatch Crest Women's Residential offers tailored rehabilitation services for adults and young adults grappling with substance abuse and accompanying mental health challenges. They provide adaptable residential care options, including extended stays, shorter programs, and 24/7 support, all designed to meet unique recovery journeys. Their therapeutic methods include 12-step integration, strategies for managing anger, and brief intervention. Additionally, Wasatch Crest provides specialized support for active military personnel, adult males, and adult females, demonstrating a commitment to inclusive care. Their dedication to high-quality, gender-focused treatment establishes Wasatch Crest as a reliable resource for individuals pursuing holistic recovery in a nurturing setting.

Walworth County Health/Human Services

Walworth County Health/Human Services, situated in Elkhorn, WI, delivers extensive treatment for substance use disorders, specifically aimed at adults who also face significant mental health challenges, as well as for children experiencing emotional issues. The center focuses on outpatient care utilizing methadone, buprenorphine, or naltrexone therapies and employs a variety of evidence-based methods, including anger management, cognitive behavioral therapy, and brief interventions. Customized treatment plans are developed for adolescents, men, and women, allowing for a wide array of individual needs to be met. This facility prides itself on providing quality support and care to both adult and senior populations, fostering a nurturing environment for those in need of addiction recovery services.

WTCR Amarillo
Amarillo, TX

At WTCR Amarillo in Amarillo, TX, adults and young adults can access outpatient services for substance use disorder and detoxification. This center excels in 12-step facilitation, anger management, and brief intervention strategies, serving both male and female individuals. They offer specialized support for pregnant and postpartum women, ensuring quality care within a nurturing setting. WTCR Amarillo provides comprehensive treatment options, including detoxification and medication-assisted treatment with methadone, buprenorphine, or naltrexone, tailored to each person's unique recovery journey. Their mission is to guide clients toward sustained sobriety and overall well-being.

WTCR Plano
Plano, TX

Situated in Plano, TX, WTCR Plano delivers outpatient detox and substance use treatment solutions for both adults and young adults. This center emphasizes 12-step facilitation, anger management, and brief intervention techniques, accommodating clients of all genders. With special attention to pregnant and postpartum women, WTCR Plano ensures personalized care tailored to various requirements. Clients seeking detox options or continuous treatment involving methadone, buprenorphine, or naltrexone can rely on receiving exceptional support. For those in need of efficient addiction treatment in Plano, WTCR Plano is committed to guiding individuals toward sustainable recovery.

WTCR Dallas
Dallas, TX

WTCR Dallas, situated in Dallas, TX, provides comprehensive outpatient services including substance abuse treatment and detox. They offer tailored programs for expectant and new mothers, serving adults and young adults across the gender spectrum. Their treatment methodologies encompass 12-step facilitation, anger management, and brief intervention. The center specializes in outpatient medication-assisted treatment, utilizing methadone, buprenorphine, or naltrexone. WTCR Dallas is committed to fostering a secure and welcoming space for individuals to begin and sustain their recovery, emphasizing personal healing and development.

Wasatch County Family Clinic

Situated in Heber City, UT, Wasatch County Family Clinic delivers a wide array of services aimed at addressing addiction for both adults and older adults. The clinic specializes in intensive outpatient programs, outpatient detox services, and therapeutic sessions, employing proven methods such as cognitive behavioral therapy and motivational interviewing. It focuses on supporting clients facing both mental health challenges and substance use disorders, including those involved with the criminal justice system. By emphasizing anger management and creating customized programs for men and women, the clinic provides exceptional care for individuals pursuing recovery from addiction and related mental health issues.

WTCR Odessa
Odessa, TX

WTCR Odessa, situated in Odessa, TX, is dedicated to providing outpatient addiction treatment, with a focus on medically supervised detox and comprehensive substance use disorder care. The center offers services including outpatient detox, and medication-assisted treatment with methadone, buprenorphine, or naltrexone, serving adults and young adults regardless of gender. WTCR Odessa utilizes proven therapeutic methods like 12-step support, anger management techniques, and brief intervention strategies to deliver thorough treatment. Furthermore, they have specific treatment plans tailored for pregnant and postpartum women. WTCR Odessa is recognized for its commitment to delivering high-quality, personalized care, making it a reliable choice for individuals pursuing effective and empathetic addiction recovery.

WTCR Temple
Temple, TX

Situated in Temple, TX, WTCR Temple delivers outpatient detox services and treatment for substance use issues for both adults and young adults. This center emphasizes methods such as 12-step facilitation, anger management, and brief intervention strategies, accommodating clients of all genders. WTCR Temple especially prioritizes the needs of pregnant and postpartum women, offering a nurturing space for those aiming to recover. Their outpatient programs for methadone, buprenorphine, or naltrexone provide tailored support for each individual. With a strong focus on high-quality care, WTCR Temple is committed to guiding individuals towards a path of sobriety.

Walden Clinic
Walden, NY

Situated in Walden, NY, Walden Clinic is a dedicated facility providing specialized outpatient services for individuals grappling with substance use disorders, co-occurring severe mental health conditions in adults, and emotional challenges in children. The clinic employs a range of therapeutic modalities, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient therapy. They also implement evidence-based interventions like cognitive behavioral therapy and contingency management, tailored to each person's needs. Walden Clinic distinguishes itself with distinct programs catering to adult men, adult women, and those affected by intimate partner violence or domestic abuse. The center extends its support to both adults and the younger population of children and adolescents, serving all genders. Walden Clinic is recognized for its thorough offerings, customized treatment strategies, and a strong dedication to delivering high-quality care.

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Situated in Winston Salem, NC, Wake Forest Baptist Health delivers extensive addiction recovery services for both adults and young adults. The facility specializes in detoxification, substance abuse treatment, and addressing co-occurring mental health issues. Available treatment modalities include intensive outpatient programs, outpatient detox, and various outpatient therapies. Prioritizing approaches such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, this center serves adult men and women facing co-occurring challenges. With customized programs designed for diverse age groups and genders, the center promotes personalized care and support, highlighting the importance of effective treatment and sustainable recovery.

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Greenville, NC

The Walter B Jones rehabilitation center, situated in Greenville, NC, delivers targeted therapies for detoxification, substance abuse, and dual diagnoses affecting both adults and youth. Through its inpatient hospital detoxification and treatment services, the center ensures thorough support within a secure setting. Employing methods such as 12-step program encouragement, anger control techniques, and concise therapeutic interventions, the center addresses the distinct requirements of each person. Specialized offerings for active-duty service members, adult men, and women elevate the standard of care. This facility is committed to aiding individuals of all genders, encompassing adults and young adults, on their path toward healing.

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Situated in Spanish Fork, UT, the Wasatch BH Special Servs District offers a wide range of addiction recovery services aimed at both adults and young adults. This center specializes in detoxification, treatment for substance use disorders, and care designed for those facing both substance use issues and significant mental health challenges. The facility provides various treatment options, including hospitalization, round-the-clock inpatient care, and extended residential programs to meet the unique needs of each client. By implementing methods such as 12-step programs, anger management techniques, and brief interventions, the center focuses on tailored treatment plans. Additionally, dedicated programs for men, women, and those who have suffered from intimate partner violence underscore the center's dedication to individualized and effective recovery solutions.

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The Wasatch BH Special Servs District, situated in Provo, UT, specializes in providing rehabilitation services for both adults and young adults facing challenges with substance use disorders alongside mental health issues. The center features a range of treatment options, including intensive outpatient programs, outpatient services, and the administration of methadone, buprenorphine, or naltrexone. Emphasizing techniques such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the facility customizes its approach to align with the specific needs of adolescents, male adults, and female adults. Additionally, it offers gender-specific programs to ensure that all individuals receive comprehensive care and supportive resources as they pursue their recovery journey.

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Abilene, TX

WTCR Abilene Inc in Abilene, TX provides a full spectrum of care for those in recovery. Their programs include outpatient detox and treatment for substance use disorders, utilizing medications such as methadone, buprenorphine, or naltrexone. The center's expertise lies in serving adults and young adults, with particular attention to pregnant and postpartum women. Employing proven methods like 12-step facilitation, anger management, and brief intervention, they deliver effective care to all genders. For specialized assistance in a supportive setting, explore the varied therapeutic paths at WTCR Abilene Inc.

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Garland, TX

Situated in Garland, TX, WTCR Garland provides outpatient detox services, treatment for substance use disorders, and outpatient programs for methadone, buprenorphine, or naltrexone. This center is dedicated to 12-step facilitation methods, anger management strategies, and brief intervention techniques. Focusing on the needs of pregnant and postpartum women, WTCR Garland caters to adults and young adults across all genders. The facility fosters a nurturing atmosphere for those striving to defeat addiction. Their customized programs and extensive care guarantee that every client gets individualized treatment to support their path to recovery.

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Irving, TX

WTCR Irving, situated in Irving, TX, provides outpatient detox and treatment solutions for substance use, specifically designed for both adults and young adults. The center features targeted support for women during pregnancy and postpartum. Treatment modalities employed include 12-step support, anger management strategies, and brief intervention methods. WTCR Irving serves both male and female clients, delivering gender-specific care when appropriate. Committed to high-quality service and personalized treatment plans, this center aims to assist individuals in conquering addiction and establishing a solid pathway to enduring recovery.

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Midland, TX

WTCR Midland, situated in Midland, TX, delivers thorough outpatient care for withdrawal management and addiction recovery. They provide services for detox as an outpatient, along with medication-assisted treatment using methadone, buprenorphine, or naltrexone, serving adults and younger adults. Their approach incorporates 12-step support, strategies for managing anger, and brief intervention techniques, adapting programs to each person's unique situation. A key feature at WTCR Midland is dedicated assistance for expectant and new mothers. Welcoming both men and women, the center fosters a nurturing space for everyone on their path to sobriety. Discover effective, individualized recovery at WTCR Midland.

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San Angelo, TX

Situated in San Angelo, TX, WTCR San Angelo specializes in outpatient detox and substance use recovery for both adults and young adults. The center includes specific programs designed for pregnant or postpartum women, providing customized care for their unique needs. Employing treatment methods such as 12-step facilitation, anger management, and brief interventions, this facility emphasizes holistic support. WTCR San Angelo serves clients of all genders, fostering a secure and welcoming atmosphere for everyone. Renowned for its high-quality care and individualized treatment plans, those in search of effective addiction recovery can find understanding and assistance at this well-regarded rehabilitation center.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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