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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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West Grove Clinic SC

West Grove Clinic SC in Kenosha, WI, is dedicated to providing expert care for adults experiencing substance use disorders alongside significant mental health challenges, as well as for children with severe emotional disturbances. The clinic offers structured programs including intensive outpatient care and various outpatient options, with medication-assisted treatment available for opioid use disorders. Employing evidence-based techniques like anger management, cognitive behavioral therapy, and motivational interviewing, the center is equipped to support active military members, teenagers, and adult males. West Grove Clinic SC extends its comprehensive rehabilitation services to seniors and adults across all genders, ensuring personalized treatment plans for optimal recovery.

West Haven Adult Behavioral Health

At West Haven Adult Behavioral Health in West Haven, CT, individuals grappling with substance use disorders alongside significant mental health challenges find comprehensive support. The center delivers outpatient programs featuring medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside traditional outpatient counseling. Their approach incorporates specialized interventions for anger management, brief therapy, and cognitive behavioral techniques. West Haven Adult Behavioral Health is committed to serving adults and young adults of all genders, providing personalized care that addresses the complexities of intimate partner and domestic violence experiences.

West Oaks Hospital LP

West Oaks Hospital LP, situated in Houston, TX, specializes in delivering extensive treatment options for individuals struggling with addiction, including both adults and children. The facility offers inpatient detox services alongside treatment for substance use issues and associated mental health disorders. With programs designed specifically for adolescents, as well as men and women, West Oaks Hospital LP addresses a variety of client needs. The center employs methods such as 12-step support, anger management techniques, and brief intervention strategies to provide personalized care for everyone. Committed to delivering high-quality services, the center aims to achieve positive outcomes for clients pursuing recovery from addiction and co-occurring conditions.

West Texas VA Healthcare Services

West Texas VA Healthcare Services, situated in Big Spring, TX, provides dedicated substance abuse recovery programs for adults and younger individuals. This center emphasizes high-quality services through its extended residential stays, day programs, and outpatient medication-assisted treatment (methadone, buprenorphine, or naltrexone). Employing strategies like 12-step integration, emotional regulation techniques, and immediate support interventions, the facility personalizes recovery plans. Designed specifically for veterans, the program serves both male and female patients. For anyone looking for thorough addiction treatment in a nurturing setting, West Texas VA Healthcare Services is committed to delivering effective support.

West Valley Detox Treatment

West Valley Detox Treatment, situated in Tarzana, CA, provides extensive long-term residential programs that concentrate on detoxification and addressing substance use disorders. This center delivers personalized care for adults facing both substance use issues and significant mental health challenges or emotional difficulties. Emphasizing 12-step facilitation, anger management, and short-term interventions, the facility serves active duty military personnel as well as adult men and women. By accommodating both adults and emerging adults, West Valley Detox Treatment prioritizes tailored care for individuals of all genders in a nurturing and supportive setting.

West Yavapai Guidance Clinic

Nestled in Prescott, AZ, West Yavapai Guidance Clinic provides comprehensive outpatient support for individuals grappling with substance use challenges. They also offer expert care for those experiencing dual diagnoses, where substance use disorders intersect with serious mental health conditions. Their recovery strategies are firmly rooted in scientifically proven methods, including techniques like anger management, cognitive behavioral therapy, and motivational interviewing. This clinic is equipped to deliver individualized programs catering to the unique needs of adolescents, victims of sexual abuse, and individuals who have experienced trauma. Serving adults, children, adolescents, and young adults across all genders, West Yavapai Guidance Clinic is dedicated to delivering high-quality rehabilitation within a nurturing setting.

Wellstone Regional Hospital
Jeffersonville, IN

Wellstone Regional Hospital, located in Jeffersonville, IN, is dedicated to detoxification, treatment for substance use, and addressing co-occurring disorders for both adults and children. This center offers comprehensive inpatient services with around-the-clock care, employing methods such as 12-step facilitation, cognitive behavioral therapy, and short-term interventions. Programs are specifically designed for various demographics, including adolescents, adult men, and women, while accommodating a diverse range of age groups like seniors, adults, and young adults. Wellstone Regional Hospital prioritizes personalized treatment plans for its clients, focusing on delivering high-quality care and support to individuals striving for recovery from addiction and mental health issues.

West Pines Behavioral Health

West Pines Behavioral Health, situated in Wheat Ridge, CO, provides extensive inpatient addiction care within a hospital environment. Their expertise lies in detoxification, managing substance use disorders, and addressing co-occurring mental health conditions in adults or emotional disturbances in children. Employing strategies such as 12-step facilitation, anger management, and brief interventions, West Pines delivers personalized treatment for adults and young adults, regardless of gender. They also feature specific programs for expectant and new mothers. Renowned for its high standards of care and customized treatment paths, West Pines Behavioral Health stands as a reliable choice for individuals pursuing sobriety.

West Ridge Center

West Ridge Center, situated in Rutland, VT, delivers extensive substance use care for adults of all genders. This establishment offers outpatient options including methadone, buprenorphine, or naltrexone, alongside regular outpatient services. It also features dedicated programs for individuals experiencing co-occurring mental health and substance use challenges. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational incentives, West Ridge Center serves adults and young adults in pursuit of effective treatment. The center’s gender-informed approach guarantees customized assistance for both men and women. For those seeking scientifically supported treatment combined with individualized attention, West Ridge Center is committed to guiding individuals toward lasting recovery.

West Central Human Service Center

Situated in Bismarck, ND, West Central Human Service Center delivers an extensive array of substance abuse treatment options for both adults and children experiencing concurrent mental health challenges. The center features intensive outpatient services, day treatment programs, and partial hospitalization, employing proven methods such as cognitive behavioral therapy and motivational strategies. Tailored programs are available for teenagers, those who have experienced trauma, and individuals with dual diagnoses. Committed to providing high-quality care, this center invites adults and seniors of all genders who are in need of focused rehabilitative support in a nurturing setting.

West Michigan Community MH

West Michigan Community MH, located in Baldwin, MI, provides targeted outpatient programs designed for individuals facing substance use challenges and dual mental health conditions. The center ensures thorough support for adults dealing with significant mental health issues and emotional difficulties in youth. Employing methods like brief intervention, motivational interviewing, and strategies for preventing relapse, this facility serves active duty service members, teenagers, and adult males. Prioritizing the needs of adults and seniors across all genders, the center creates personalized treatment plans aimed at fostering recovery and enhancing well-being. For those in search of effective care within a nurturing atmosphere, West Michigan Community MH is an essential option for rehabilitation support.

WellStone Inc
Huntsville, AL

WellStone Inc, situated in Huntsville, AL, provides extensive support for individuals grappling with addiction and co-occurring mental health concerns. Their diverse treatment array encompasses intensive outpatient, extended residential stays, and standard outpatient services, serving both adults and younger individuals. This establishment excels in cognitive behavioral therapy and employs cutting-edge methods such as community reinforcement with vouchers and contingency management. WellStone Inc offers specialized tracks for teenagers, adult women, and those with dual diagnoses, guaranteeing customized attention. Committed to excellence and personalized recovery paths, WellStone Inc strives to empower clients toward sustained well-being.

WellStone Inc
Huntsville, AL

Situated in Huntsville, AL, WellStone Inc delivers a wide range of rehabilitation services aimed at adults and children facing challenges with substance use disorders and concurrent mental health conditions. The center features intensive outpatient programs, outpatient detox services, and tailored initiatives for younger individuals. Emphasizing personalized treatment, WellStone Inc utilizes evidence-based methodologies such as 12-step programs, anger management strategies, and brief intervention techniques. This facility welcomes both men and women, fostering an inclusive and nurturing atmosphere. For those in search of effective addiction recovery solutions for themselves or their loved ones, WellStone Inc is committed to providing compassionate and quality care to support enduring recovery.

West Midtown Management Group

West Midtown Management Group, situated in New York, NY, delivers targeted substance abuse recovery solutions for adults and adolescents. This facility offers ambulatory care options such as methadone/buprenorphine or naltrexone therapy, general outpatient support, and employs strategies like cognitive behavioral therapy, motivational interviewing, and relapse prevention. Recognizing distinct needs, they provide specific plans for adult males, adult females, and individuals living with HIV/AIDS, guaranteeing personalized attention. Catering to both genders, West Midtown Management Group is dedicated to providing excellent, all-encompassing restorative services aimed at fostering enduring sobriety.

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Bangor, ME

Wellspring Inc, situated in Bangor, ME, specializes in substance use rehabilitation specifically for adult women. The center offers both long-term and 24-hour residential treatment programs designed for individuals who have faced intimate partner violence and domestic abuse. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention, Wellspring Inc delivers exceptional care for clients on their recovery journey. It also features distinct programs aimed at active duty military members, which distinguishes this facility from others. Catering to women across various age groups—adults, seniors, and young adults—Wellspring Inc creates a nurturing atmosphere for those seeking extensive addiction support.

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Cullman, AL

WellStone Inc, situated in Cullman, Alabama, delivers thorough recovery programs for individuals facing addiction and simultaneous severe mental health challenges. They offer intensive outpatient, outpatient, and standard outpatient care plans designed for adults and young adults. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and contingency management/motivational incentives, WellStone Inc ensures effective and individualized support. Specific programs are offered for teenagers, accommodating both male and female participants. Prioritizing high-quality treatment and a diverse range of services, WellStone Inc is a reliable choice for individuals pursuing rehabilitation.

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West Central Mental Health Center Inc, situated in Canon City, CO, offers targeted outpatient care for individuals facing addiction and concurrent mental health challenges. Their services, including anger management, cognitive behavioral therapy, and brief interventions, are customized to meet the unique requirements of each patient, encompassing adults and children. The center provides specialized programs for active military members, adult men, and women, fostering an inclusive and encouraging atmosphere. Catering to adults and seniors across all gender identities, West Central Mental Health Center Inc is dedicated to delivering excellent, scientifically supported treatments to promote sustained recovery and enhanced mental health.

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West Central WI Behavioral Health in Whitehall, WI, provides outpatient services for individuals struggling with substance use, including specialized support for those with co-occurring mental health conditions. Their treatment plans are customized using approaches like brief intervention, cognitive behavioral therapy, and the Matrix Model. The center serves adults and young adults, offering a supportive and personalized recovery journey. West Central WI Behavioral Health is recognized for its dedication to effective, client-centered rehabilitation.

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West Michigan Community MH, situated in Hart, MI, offers outpatient services for substance use disorders, alongside tailored treatment for individuals facing both substance use issues and severe mental health disorders. The facility administers outpatient treatment options including methadone/buprenorphine and naltrexone, while also providing standard outpatient care. Employing techniques like brief intervention, motivational interviewing, and strategies for preventing relapse, the center customizes its approach to suit each client's unique circumstances. With dedicated programs for active military members, teenagers, and adult males, West Michigan Community MH supports adults and seniors across the gender spectrum. The center is committed to delivering exceptional care and specialized treatment options, establishing itself as an essential resource for comprehensive rehabilitation services.

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West Michigan Community MH, situated in Ludington, MI, is dedicated to providing focused care for adults struggling with addiction alongside significant mental health challenges, as well as for children experiencing severe emotional difficulties. The center offers outpatient solutions, encompassing medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic framework incorporates proven methods like brief intervention, motivational interviewing, and strategies for preventing relapse. Distinct programs are available for active military members, teenagers, and adult males. Catering to a diverse population of adults and seniors regardless of gender, West Michigan Community MH is committed to delivering personalized, high-quality rehabilitation services, establishing itself as a reliable resource for comprehensive recovery.

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Situated in Cody, WY, West Park Behavioral Health provides an extensive array of rehabilitation services aimed at adults and the elderly. This center is dedicated to detoxification, treatment for substance abuse, and addressing concurrent mental health issues. Emphasizing intensive outpatient programs and outpatient detox, West Park Behavioral Health utilizes proven methods, including cognitive behavioral therapy and motivational interviewing. Tailored programs are available for clients managing both pain and substance use challenges. The facility is designed to offer specialized care for men and women alike, prioritizing effective treatment for those on the path to recovery from addiction and dual diagnosis challenges.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)