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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Better Life Partners
Montpelier, VT

Better Life Partners, located in Montpelier, VT, provides a range of outpatient programs designed for individuals battling substance use issues, including both adults and young adults. This facility emphasizes personalized care, incorporating techniques such as cognitive behavioral therapy, anger management, and brief interventions. Better Life Partners accommodates both men and women, including those who face dual challenges of mental health and substance use disorders. The center also offers outpatient treatment options with methadone/buprenorphine or naltrexone, ensuring that all clients receive effective support on their path to recovery.

Better Life Partners

Situated in Nashua, NH, Better Life Partners provides a wide range of substance use recovery programs designed for both adults and young adults. This center offers outpatient options such as treatments involving methadone, buprenorphine, or naltrexone, in addition to standard outpatient services, anger management, short interventions, and cognitive behavioral therapy. It features specialized programs aimed at adult men, adult women, and those facing both mental health and substance use challenges, addressing a variety of requirements. Better Life Partners is committed to offering personalized support for all clients, ensuring high-quality treatment to assist individuals in their recovery journeys.

Better Outlook
Saint Paul, MN

"Better Outlook" located in Saint Paul, MN, presents a wide range of outpatient services aimed at addressing substance use disorders and associated mental health challenges for both adults and children dealing with emotional issues. The center has tailored programs to support active military personnel, adolescents, and adult males, welcoming a diverse clientele that spans from young children to older adults. The treatment methods employed include cognitive behavioral therapy, counseling for substance use disorders, and options for telehealth services. Committed to providing high-quality care, the facility also offers outpatient treatment involving methadone, buprenorphine, or naltrexone, in addition to standard outpatient therapies. Both men and women can access these customized rehabilitation services designed to meet their unique needs.

Better Life Recovery LLC

Better Life Recovery LLC in Caldwell, NJ, provides thorough support for individuals battling addiction, including those managing significant mental health conditions. Their range of services includes intensive outpatient, standard outpatient, and day treatment programs, all designed with individualized care in mind. The facility emphasizes a multi-faceted recovery strategy incorporating 12-step principles, anger management techniques, and cognitive behavioral therapy. Catering to both men and women, Better Life Recovery LLC is dedicated to crafting custom treatment paths that acknowledge the distinct hurdles each person faces. Discover a supportive environment focused on effective healing and recovery at this esteemed facility.

BestCare Treatment Services

BestCare Treatment Services, located in Redmond, OR, provides thorough substance use disorder care for adults and adolescents facing co-occurring mental health conditions. Their services include outpatient options such as medication-assisted treatment (methadone, buprenorphine, naltrexone) alongside standard outpatient care. The center emphasizes approaches like 12-step program integration, emotional regulation skills, and short-term therapeutic strategies. They serve active military members, adult men, and adult women, with gender-specific programming designed to meet diverse needs. BestCare Treatment Services is committed to delivering high-quality, personalized support to guide individuals toward sustained recovery.

BestCare Treatment Services

BestCare Treatment Services in Redmond, OR, provides thorough outpatient rehabilitation services designed for adults and adolescents facing substance abuse and accompanying mental health challenges. The center offers dedicated care for active military members, adult males, and adult females, addressing a wide spectrum of individual requirements. Through its emphasis on 12-step facilitation, anger management, and brief intervention strategies, BestCare Treatment Services guarantees personalized treatment and assistance. Clients can expect high-quality care adjusted to their unique situations, whether they require standard outpatient services or specialized outpatient treatment involving methadone, buprenorphine, or naltrexone. The availability of gender-specific programs for both men and women promotes a secure and encouraging setting for healing.

BestSelf Behavioral Health Lower West

Situated in Buffalo, NY, BestSelf Behavioral Health Lower West delivers extensive outpatient rehabilitation services for those facing substance use challenges and concurrent mental health disorders. This center focuses on providing tailored treatment for adults experiencing significant mental health conditions and children grappling with severe emotional issues. Emphasizing techniques such as anger management, cognitive behavioral therapy, and short-term interventions, the facility supports active military members, teenagers, and adult males. Catering to clients of all genders and ages, this program is dedicated to offering exceptional care and individualized assistance to foster enduring recovery.

Better Life Partners

Better Life Partners in Lebanon, NH, delivers tailored programs for addiction recovery. Their offerings include outpatient services like methadone/buprenorphine or naltrexone treatment, standard outpatient care, and various therapies such as anger management, cognitive behavioral therapy, and brief intervention. This center emphasizes personalized support for adult men and women, including those with dual mental health and substance use diagnoses. Better Life Partners is dedicated to providing effective care for adults and young adults, assisting them in attaining sustained abstinence and improved health.

BestCare Treatment Services

BestCare Treatment Services in Prineville, OR, delivers all-encompassing care for individuals, young and old, facing substance use disorders alongside significant mental health conditions or emotional distress. They offer a range of services including outpatient care, medication-assisted treatment with methadone/buprenorphine, and naltrexone. Therapeutic interventions at BestCare include support for the 12-step model, anger management techniques, and brief intervention strategies. The center also features tailored programs for active military personnel, teenagers, and adult males, accommodating various age demographics and genders. Recognized for its personalized approach and dedication to fostering recovery, BestCare provides excellent treatment for those needing assistance with addiction and mental well-being.

BestCare Treatment Services

BestCare Treatment Services, situated in Madras, OR, delivers thorough care for individuals of all ages struggling with substance use and co-occurring severe mental health issues. The center offers structured intensive outpatient and outpatient services, incorporating medication-assisted treatment with options such as methadone, buprenorphine, or naltrexone. Their approach emphasizes 12-step program integration, anger control techniques, and concise intervention strategies. BestCare is equipped to support active military members, teenagers, and adult men, as well as female clients, ensuring personalized and superior rehabilitation services within the area.

Better Life Partners

Situated in Rochester, NH, Better Life Partners delivers extensive outpatient services for individuals struggling with substance use issues, catering to both adults and young adults. The center features tailored programs designed specifically for adult men, adult women, and those dealing with concurrent mental health and substance use challenges. Their treatment modalities encompass anger management, brief interventions, and cognitive behavioral therapy. Committed to delivering high-quality care, Better Life Partners offers outpatient options that include methadone/buprenorphine or naltrexone treatment, alongside standard outpatient services. This establishment supports both male and female clients, fostering a nurturing atmosphere for those in pursuit of effective addiction recovery solutions.

BestCare/Latino Services

BestCare/Latino Services located in Madras, OR is an esteemed rehabilitation facility that specializes in addressing substance abuse issues and co-occurring mental health conditions in both adults and children. The center offers a range of treatment options, including long-term residential programs, outpatient care, and standard outpatient services that are customized to meet the specific needs of each individual. Emphasizing a combination of 12-step support, anger management techniques, and brief intervention strategies, this facility aims to provide thorough care for its clients. Additionally, it features distinctive programs for active duty military personnel, adult men, and survivors of intimate partner violence, which differentiates it from other providers. Catering to adults, seniors, and young adults, BestCare/Latino Services is dedicated to delivering high-quality care and assistance to male clients on their recovery journey.

Better Beginnings Healthcare Solutions

Better Beginnings Healthcare Solutions, situated in Fayetteville, NC, provides comprehensive rehabilitation programs. The center addresses detoxification and substance use disorders, offering specialized support for those with co-occurring mental health issues in adults or emotional disturbances in young people. Services include outpatient care, including methadone/buprenorphine or naltrexone treatment, and standard outpatient programs. Employing techniques such as anger management, brief intervention, and cognitive behavioral therapy, the center delivers personalized treatment for adults and children across all genders, highlighting a unique commitment to tailored care.

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Klamath Falls, OR

Situated in Klamath Falls, OR, BestCare delivers exceptional services for addiction recovery. This establishment features extensive detox programs and treatment for substance use within a nurturing setting. The center focuses on long-term residential treatment, residential detox, and around-the-clock support. BestCare employs methodologies such as 12-step support, anger management, and concise intervention techniques. Specialized programs are available for active duty military members, adult men, and adult women. Catering to adults and young adults of all genders, this facility guarantees high-quality care through customized treatment plans designed to meet each person's unique requirements.

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BestCare Treatment Services located in Redmond, OR, provides a wide range of addiction rehabilitation programs for both adults and young adults. This center features residential detox services along with multiple types of residential treatment options, including short-term stays. It is primarily focused on addressing substance use disorders alongside concurrent mental health issues. BestCare Treatment Services employs customized treatment methods like 12-step support, anger management, and brief interventions to offer personalized care. Specialized programs cater to active duty military personnel, as well as adult men and women. Committed to delivering high-quality and empathetic support, this center aims to assist individuals in achieving enduring recovery.

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Situated in Bend, Oregon, BestCare Treatment Services provides extensive outpatient treatment for substance use disorders aimed at both adults and young adults. This facility is particularly adept at addressing co-occurring disorders, including significant mental health challenges in adults and emotional issues in children. Emphasizing approaches such as 12-step support, anger management, and targeted interventions, the center delivers customized care designed to meet the specific requirements of each individual. Specialized programs are available for active military members and adult men and women. With options for outpatient treatment using methadone, buprenorphine, or naltrexone, BestCare Treatment Services is committed to offering superior support for clients on their journey to recovery.

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Situated in Gloucester, MA, Beth Israel Lahey Health Behav Servs provides extensive outpatient rehabilitation services tailored for adults and young adults facing challenges related to substance use disorders and concurrent mental health issues. The center is adept at managing detoxification, offering substance use treatment, and creating customized programs for individuals with severe mental health conditions. Emphasizing approaches such as cognitive behavioral therapy, motivational interviewing, and contingency management, this facility delivers personalized care aimed at both men and women. It also features outpatient detox options and medication-assisted treatments using methadone or buprenorphine, ensuring high-quality support for those on their recovery journey.

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Manchester, NH

Situated in Manchester, NH, Better Life Partners specializes in outpatient programs for substance use treatment aimed at both adults and young adults. This center offers a variety of targeted services, which include outpatient options for methadone/buprenorphine and naltrexone, along with anger management, brief intervention, and cognitive behavioral therapy. Emphasizing personalized care, Better Life Partners serves adult men and women, addressing the needs of clients dealing with co-occurring mental health and substance use issues. Their gender-specific programs are designed to provide customized support for male and female clients alike. Committed to delivering top quality, evidence-based treatment, Better Life Partners helps individuals embark on their journey toward sustainable recovery.

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Manchester, NH

Better Life Partners, situated in Manchester, NH, provides a range of outpatient programs for substance use treatment designed specifically for adults and young adults. The center features targeted outpatient therapies using methadone, buprenorphine, or naltrexone, alongside general outpatient services. It employs various techniques such as anger management, brief interventions, and cognitive behavioral therapy. Committed to personalized care, the facility has distinctive programs for adult men and women, as well as for individuals dealing with both mental health issues and substance use disorders. Better Life Partners aims to deliver exceptional care and assistance to all clients embarking on their recovery journey from addiction.

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Scarborough, ME

Situated in Scarborough, ME, Better Life Partners delivers extensive substance use treatment options through customized outpatient programs designed to address personal requirements. This facility offers outpatient treatments including methadone/buprenorphine and naltrexone, alongside standard outpatient services, while integrating methods like anger management, brief intervention, and cognitive behavioral therapy. With tailored programs for adult males, adult females, and those facing both mental health and substance use challenges, this center serves adults and young adults from all backgrounds. Better Life Partners emphasizes high-quality care and efficient treatment methodologies to aid individuals in their recovery journey.

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Westborough, MA

Better Life Partners, situated in Westborough, MA, stands as a leading addiction treatment center dedicated to adults and young adults. They provide varied levels of care, including outpatient services and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their therapeutic interventions are grounded in scientific evidence and include methods like anger management, brief intervention, and cognitive behavioral therapy. Better Life Partners is also distinguished by its specialized programs catering to adult men, adult women, and individuals facing dual diagnoses of mental health and substance use disorders, ensuring individualized support. Their commitment is to delivering effective and high-quality addiction recovery for all clients, irrespective of gender.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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