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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Bi Bett Corp
Concord, CA

Bi Bett Corp, situated in Concord, CA, is a premier rehabilitation facility dedicated to providing thorough detoxification and treatment for substance use disorders. It features residential and short-term care options, with expertise in anger management, brief interventions, and cognitive behavioral therapy. The center primarily serves adult women and those affected by intimate partner violence, domestic abuse, or sexual trauma. With a commitment to adults, seniors, and young adults, Bi Bett Corp offers focused care specifically for women. Discover personalized and compassionate addiction recovery solutions at Bi Bett Corp, designed for successful outcomes.

Bio Medical Behavioral Healthcare Inc

Bio Medical Behavioral Healthcare Inc, located in Roseville, MI, delivers extensive treatment options for adults and young adults facing addiction and accompanying mental health challenges. Their offerings encompass detox, outpatient care, and tailored programs for individuals affected by domestic abuse. The center employs proven methods like 12-step support, anger control techniques, and short-term counseling to aid in the recovery process. Emphasizing personalized attention, this facility serves adult men and women, fostering a secure and nurturing space for wellness. For top-tier addiction recovery with a customized approach, look to Bio Medical Behavioral Healthcare Inc.

Blackberry Center
Saint Cloud, FL

Situated in Saint Cloud, FL, Blackberry Center delivers a wide range of rehabilitation services tailored for both adults and young adults facing substance use challenges along with concurrent mental health disorders. The center features hospital-based inpatient detoxification and therapeutic programs that emphasize 12-step support, cognitive behavioral techniques, and strategies for preventing relapse. Blackberry Center is dedicated to serving adult males and females, including those who have undergone experiences related to intimate partner violence. Upholding a strong commitment to high standards of care, this facility provides a nurturing and effective atmosphere for individuals in need of support.

Blanchard Institute
Huntersville, NC

Situated in Huntersville, NC, the Blanchard Institute provides extensive treatment for adults dealing with substance use issues, incorporating transitional housing and sober living arrangements. The center has a focus on co-occurring mental health disorders alongside substance use, offering both intensive outpatient and day treatment programs that utilize evidence-based practices, including 12-step facilitation and anger management strategies. With customized programs designed for men and women, as well as those who have faced intimate partner violence, Blanchard Institute is dedicated to delivering individualized support for every client. Catering to both younger and older adults, this facility emphasizes high-quality care within a nurturing environment for individuals pursuing recovery.

Blanchard Institute
Charlotte, NC

Blanchard Institute, situated in Charlotte, NC, delivers a full spectrum of care for substance abuse disorders. Their offerings encompass detox, drug and alcohol rehabilitation, temporary accommodations, and supportive sober living environments for adults and adolescents. Various treatment modalities are available, including intensive outpatient, outpatient, and day treatment programs, all customized to each person's unique recovery plan. Specialized tracks are designed for adult men, adult women, and individuals affected by domestic or intimate partner violence. Employing evidence-based methods such as 12-step support, emotional regulation skills, and short-term counseling, the facility guides individuals toward a complete and individualized path to wellness. Blanchard Institute's commitment to superior treatment makes it a reliable option for those in pursuit of impactful and encouraging addiction recovery.

Bigfoot Counseling LLC

Bigfoot Counseling LLC, located in Post Falls, ID, delivers outpatient services for adults managing substance use disorders alongside mental health challenges, and for children experiencing significant emotional disturbances. Their therapeutic methods include anger management, cognitive behavioral therapy, and motivational interviewing, offering targeted support for active duty military, teenagers, and adult men. The center caters to a diverse clientele, including adults and older adults of any gender, with customized programs designed for personal attention and thorough assistance. Bigfoot Counseling LLC is a reliable provider of effective and empathetic addiction recovery solutions in the Post Falls region, emphasizing proven treatment strategies and a dedication to high-quality care.

Black Bear Treatment Center LLC

Situated in Sautee Nacoochee, GA, Black Bear Treatment Center LLC provides an extensive variety of rehabilitation services. This center focuses on detoxification, treatment for substance use disorders, and transitional living arrangements, serving adult men, women, and young adults. It features diverse treatment modalities, including intensive outpatient care, long-term residential stays, and outpatient services, ensuring personalized support through methods like 12-step programs, anger management techniques, and brief interventions. Moreover, Black Bear Treatment Center LLC has specialized programs designed for individuals who have faced sexual abuse. Renowned for its high-quality care and customized treatment plans, this facility is a reliable option for individuals seeking to recover from addiction.

Bleuler CD Recovery Services

Situated in Forest Hills, NY, Bleuler CD Recovery Services delivers outpatient treatment for substance use aimed at both adults and children, with an emphasis on addressing co-occurring mental health issues. The center features targeted programs specifically designed for active duty military personnel, teenagers, and adult males. Their treatment methods encompass 12-step facilitation, anger management techniques, and brief intervention strategies. With services customized for all genders, this facility guarantees holistic support for every individual. Whether clients need standard outpatient services or options like methadone and buprenorphine, this center is committed to providing high-quality care to facilitate effective recovery journeys.

Blue Heron Neurofeedback and

Blue Heron Neurofeedback and Rehabilitation Center located in North Conway, NH, provides outpatient services aimed at addressing substance misuse and related mental health issues in adults, as well as emotional challenges in children. The facility focuses on 12-step programs, anger management techniques, and short-term interventions, serving a diverse population that includes active military personnel, teenagers, adult males, and older adults. With distinct programs tailored for men and women, this center ensures a nurturing atmosphere for recovery. Whether individuals are looking for ongoing outpatient support or need help with methadone/buprenorphine treatment, they can access customized assistance at this center.

Blue Heron Neurofeedback and

Blue Heron Neurofeedback is dedicated to providing extensive outpatient care for adults dealing with substance abuse and mental health issues that often coexist, as well as addressing serious emotional challenges in children. This center features programs specifically designed for various groups, including active military personnel, adolescents, and adult males, ensuring that treatment is customized to meet the unique needs of each population. Utilizing strategies such as 12-step support, anger management techniques, and quick intervention methods, the facility prioritizes personalized treatment approaches. Catering to adults and seniors of all gender identities, Blue Heron Neurofeedback ensures a nurturing atmosphere where individuals can access top-notch care. Whether one is looking for outpatient methadone/buprenorphine support or general outpatient treatment, this center in Littleton, NH, is equipped to provide valuable assistance.

BHRS The Center
Merced, CA

BHRS The Center, located in Merced, CA, delivers an extensive selection of treatment services aimed at addressing substance use and concurrent mental health issues for both adults and children. Featuring intensive outpatient, outpatient, and standard outpatient programs, the center emphasizes personalized care through methodologies like 12-step facilitation, anger management, and short intervention strategies. Additionally, specialized programs are designed for adult men and women, as well as clients who have faced intimate partner violence. This facility caters to individuals of all genders, committed to offering top-notch, evidence-supported treatment that aids individuals in their recovery journey.

Black Rock Integrative Medicine

Black Rock Integrative Medicine in Hagerstown, MD, offers outpatient substance use treatment with a focus on quality care and evidence-based approaches. The center provides outpatient methadone/buprenorphine or naltrexone treatment, regular outpatient treatment, and specialized programs for active duty military personnel, adolescents, and adult men. Treatment approaches include brief intervention, cognitive behavioral therapy, and relapse prevention strategies. Serving adults and seniors of all genders, Black Rock Integrative Medicine strives to deliver comprehensive and personalized care to support individuals on their journey to recovery.

Bio Medical Behavioral Health System

Bio Medical Behavioral Health System, situated in Flint, MI, provides complete addiction recovery services for adults and adolescents. This facility excels in detox, addressing substance use, and managing dual diagnoses. They offer robust intensive outpatient and outpatient options, including outpatient detox. Specializing in 12-step integration, anger control, and concise therapeutic strategies, Bio Medical Behavioral Health System serves adult males and females, alongside survivors of domestic abuse. Their individualized treatment plans ensure each patient receives bespoke support, prioritizing effective, science-backed methods for sustained healing.

BJC Behavioral Health
Saint Louis, MO

Saint Louis, MO's BJC Behavioral Health provides extensive outpatient services. They focus on addiction recovery and dual diagnoses, offering personalized support for adults with severe mental health conditions and children with significant emotional challenges. Their treatment methods encompass anger management, cognitive behavioral therapy, and concise interventions. Distinctive programs are designed for adult women, survivors of sexual abuse, and those impacted by trauma. Serving all age groups, from children to adults, BJC Behavioral Health emphasizes high-quality, individualized care. They also offer gender-specific treatments to support male and female clients on their journey to healing.

BJC Behavioral Health
Farmington, MO

BJC Behavioral Health, situated in Farmington, MO, provides extensive outpatient care for those needing assistance with substance abuse and co-occurring mental health conditions. The facility features distinct programs designed for adult women, individuals with a background of sexual abuse, and those who have endured trauma. Their therapeutic methods encompass anger management, brief intervention, and cognitive behavioral therapy. Prioritizing high-quality services, BJC Behavioral Health supports both adults and young people, offering outpatient medication-assisted treatment with methadone/buprenorphine and naltrexone. This center is inclusive, accepting clients of all genders and fostering a space dedicated to healing and recovery.

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Boston, MA

Bicycle Health, located in Boston, MA, provides outpatient services for those dealing with substance use issues, specifically focusing on treatments involving methadone, buprenorphine, and naltrexone. The center combines regular outpatient care with innovative methods, including brief interventions, cognitive behavioral therapy, and strategies for preventing relapse. What sets Bicycle Health apart is its dedication to creating customized treatment plans suited for both adults and young adults across all genders. Aiming for high-quality support, this center prioritizes a personalized strategy to assist individuals in their recovery journey. For those in search of compassionate and effective addiction treatment, Bicycle Health delivers a wide range of services tailored to meet individual needs.

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The Birmingham VA Healthcare System in Birmingham, AL, provides extensive care for substance use issues in adults and adolescents. This institution focuses on addressing concurrent substance use disorders alongside significant mental health conditions in adults and severe emotional challenges in youth. Offering diverse treatment methods like intensive outpatient services and outpatient care with methadone/buprenorphine or naltrexone, the center employs scientifically validated strategies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. Distinct programs are available for individuals experiencing co-occurring pain and substance use disorders. Serving both men and women, this center is dedicated to delivering high-quality, personalized treatment.

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Florissant, MO

BJC Behavioral Health, situated in Florissant, MO, is a dedicated facility providing advanced care for adults and children grappling with substance abuse alongside significant mental health conditions or emotional difficulties. The center's offerings include flexible outpatient programs, featuring methadone and buprenorphine services, as well as cognitive behavioral therapy. Special tailored initiatives are available for adult women, individuals who have experienced sexual abuse, and those affected by trauma. Emphasizing anger management and concise intervention strategies, the facility ensures personalized support for all clients, regardless of gender. BJC Behavioral Health is committed to delivering effective, customized treatment pathways to aid individuals in their recovery from addiction and mental health struggles.

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Bliss Poston the Second Wind, located in New York, NY, provides outpatient detox and treatment for adults and young adults dealing with substance use issues. This center is particularly adept at addressing both substance use and significant mental health challenges in adults, while also supporting children with emotional issues. Emphasizing therapies such as cognitive behavioral therapy, motivational interviewing, and counseling specifically for substance use disorders, the facility offers tailored care to both men and women. Specialized programs are available for clients facing co-occurring mental health and addiction problems. For individuals in need of thorough and customized addiction recovery solutions, Bliss Poston the Second Wind ensures a nurturing and effective rehabilitation experience.

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Salt Lake City, UT

Bloc Outpatient, located in Salt Lake City, UT, is a specialized rehabilitation center focused on assisting adult males who are dealing with substance use issues and co-existing serious mental health disorders. The center provides a range of programs, including intensive outpatient, outpatient, and standard outpatient services, with an emphasis on 12-step support, anger management techniques, and cognitive behavioral therapy. It also features distinct programs designed specifically for adult male survivors of intimate partner violence and sexual trauma, highlighting its unique approach. Catering to adults, seniors, and younger men, Bloc Outpatient is committed to offering personalized, high-quality care to aid clients on their path to recovery.

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At Blue Heron Neurofeedback and in Gorham, NH, adults facing substance use disorders alongside significant mental health conditions or emotional struggles in children receive specialized outpatient care. The center excels in facilitating 12-step programs, anger management techniques, and brief intervention strategies, offering customized support for active military personnel, teenagers, and adult males. Services extend to adults and seniors of any gender, with outpatient offerings including methadone, buprenorphine, and naltrexone therapies. Blue Heron Neurofeedback and is committed to delivering high-quality, personalized treatment plans to assist individuals on their journey to recovery from addiction and mental health concerns.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)