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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.

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Terros Health
Phoenix, AZ

Situated in Phoenix, AZ, Terros Health delivers extensive outpatient rehabilitation services for adults and elderly individuals facing substance use challenges. The center specializes in assisting clients who experience both mental health issues and substance use disorders, as well as those dealing with chronic pain alongside addiction. Employing proven techniques such as cognitive behavioral therapy, community reinforcement with vouchers, and the Matrix Model, Terros Health guarantees personalized and high-standard care. The facility offers specific programs designed for both men and women, including those connected to the criminal justice system. For services like outpatient methadone/buprenorphine or naltrexone therapy, Terros Health stands out as a reliable option for compassionate and effective recovery support.

Texas Clinic
Houston, TX

Situated in Houston, TX, the Texas Clinic specializes in providing targeted substance abuse treatment through various outpatient programs designed to meet individual requirements. The center employs evidence-based methods, including cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, offering thorough care for adult men, women, and those who are pregnant or recently gave birth. With an emphasis on supporting both adults and young adults of all genders, the Texas Clinic fosters a welcoming and supportive atmosphere conducive to recovery. Its outpatient services involving methadone, buprenorphine, or naltrexone treatment, in addition to standard outpatient treatment options, highlight its dedication to delivering high-quality care and holistic recovery solutions for individuals battling addiction.

Texas Health Recovery and

Texas Health Recovery, located in Mansfield, TX, provides a wide array of services aimed at overcoming addiction. The center focuses on detox processes, treatment for substance use disorders, and support for individuals facing both addiction and serious mental health challenges. Their offerings are designed for adults and young adults and include options such as intensive outpatient programs, outpatient day treatment, and partial hospitalization. Employing evidence-based methods like 12-step programs, cognitive behavioral therapy, and motivational interviewing, the center emphasizes personalized treatment. Furthermore, they offer specialized programs for adult men, women, and survivors of domestic violence. Committed to high-quality care and customized treatment plans, this center strives to support clients in achieving sustainable recovery.

Texas Native Health

At Texas Native Health in Dallas, TX, adults grappling with substance use disorders alongside serious mental health conditions can access specialized outpatient care. The facility also extends its services to children and adolescents experiencing significant emotional disturbances, offering them dedicated support. Their therapeutic offerings include facilitating 12-step programs, anger management techniques, and brief intervention strategies. Texas Native Health is committed to a personalized approach, providing tailored treatment plans for both male and female clients. They distinguish themselves by crafting unique programs that meet the specific requirements of each person, thereby delivering effective treatment for individuals addressing addiction and mental well-being concerns.

The Clinic
South Williamson, KY

The facility in South Williamson, KY, provides a full spectrum of addiction recovery support, encompassing detox and treatment for substance reliance. They emphasize intensive outpatient, standard outpatient, and outpatient detox programs, delivering customized plans through techniques like motivational interviewing, counseling for substance use disorders, and virtual therapy. Specific treatment tracks are available for active military, adult males, adult females, and families with children or teens. Their gender-specific programs ensure each client receives care suited to their unique needs. Discover dedicated, personalized assistance aimed at fostering long-term sobriety and a successful return to wellness at this center.

Terrace House
Buffalo, NY

Situated in Buffalo, NY, Terrace House provides premier detox and substance abuse treatment options. Emphasizing residential support, this center ensures continuous assistance for individuals on their recovery journey. Terrace House employs a range of methodologies, such as 12-step programs, anger management techniques, and brief therapeutic interventions, to meet varying requirements. Specialized programs for adult men and women are offered, accommodating adults and young adults of any gender. The facility’s dedication to high-quality care and personalized treatment solidifies Terrace House as a reliable option for those ready to begin their journey towards sobriety.

Terrace House
Buffalo, NY

Nestled in Buffalo, NY, Terrace House provides extensive support for overcoming addiction. This establishment focuses on detox and substance abuse therapy, offering live-in accommodations through round-the-clock and brief residential options. Employing methods like 12-step support, cognitive behavioral therapy, and brief intervention, Terrace House serves adult men and women, including survivors of intimate partner or domestic abuse. Catering to both adults and younger adults, the center features distinct programs for various gender identities. Terrace House distinguishes itself with its high standards of care and customized treatment plans, positioning it as a premier destination for those pursuing successful recovery.

Terrebonne Behavioral Health Center

Situated in Houma, LA, Terrebonne Behavioral Health Center delivers a complete spectrum of substance abuse treatment for individuals of all ages facing concurrent mental health challenges. They offer intensive outpatient services, regular outpatient care, and specific medication-assisted treatment plans utilizing methadone, buprenorphine, or naltrexone. Their therapeutic framework includes anger management, brief intervention strategies, and cognitive behavioral therapy, all adapted to meet each person's distinct requirements. Specialized programming is available for teenagers, adult men, and adult women. Catering to adults and older adults across all genders, this center is dedicated to providing high-quality, evidence-informed care to foster enduring recovery.

Terry Reilly Health Services

Outpatient substance use and co-occurring disorder treatment in Boise, Idaho, for all ages, with buprenorphine and naltrexone and programs for adolescents, veterans, and pregnant and postpartum women. Terry Reilly Health Services accepts Medicare, Medicaid, TRICARE, and SAMHSA block grants, with a sliding fee scale and Spanish and sign language services.

Terry Reilly Health Services

Part of Community Health Clinic Inc, this Nampa, Idaho location provides outpatient substance use treatment with buprenorphine and naltrexone for adolescents through seniors. Specialized groups include pregnant and postpartum women, veterans, military families, and criminal justice clients. Medicaid, Medicare, TRICARE, SAMHSA block grants, and sliding fee payments are accepted, with services in Spanish and sign language.

Terry Reilly Health Services

Outpatient substance use treatment with buprenorphine and naltrexone is provided at this Caldwell, Idaho clinic, part of Community Health Clinic Inc. Adolescents through seniors are served, with programs for pregnant and postpartum women, veterans, military families, and forensic clients. Medicaid, Medicare, TRICARE, SAMHSA block grants, and a sliding fee scale apply, with services in Spanish and sign language.

Terry Reilly Health Services Florence

This Meridian, Idaho clinic, part of Community Health Clinic Inc, provides outpatient substance use treatment with buprenorphine and naltrexone. Care is available for adolescents through seniors, including pregnant and postpartum women, veterans, military families, and criminal justice clients. Medicaid, Medicare, TRICARE, SAMHSA block grants, and a sliding fee scale help cover costs.

Terry Reilly Health Services Latah

Outpatient substance use treatment in Boise, Idaho, with buprenorphine and naltrexone available for opioid and alcohol use disorders. Part of Community Health Clinic Inc, the clinic serves adolescents through seniors, including pregnant and postpartum women, veterans, and trauma survivors. Medicaid, Medicare, TRICARE, SAMHSA block grants, and a sliding fee scale are accepted, with services in Spanish and sign language.

Texas Health Huguley Forth Worth South

Texas Health Huguley Fort Worth South in Burleson, Texas, combines hospital inpatient detox and inpatient treatment with partial hospitalization and intensive outpatient care, using buprenorphine and naltrexone. Adults and seniors are served. Medicare, Medicaid, TRICARE, and state-financed plans are accepted.

Texas Treatment Centers Inc

Texas Treatment Centers Inc in Houston, Texas provides outpatient medication-assisted treatment with methadone, buprenorphine, and naltrexone for opioid use disorder. Programs serve veterans, military families, clients with HIV or AIDS, and people with co-occurring disorders. Medicare, Medicaid, TRICARE, and payment assistance are accepted, with Spanish-language services available.

The Center at
Denver, CO

The Raleigh House, listed as The Center at, in Denver, Colorado offers outpatient day treatment or partial hospitalization and intensive outpatient care with buprenorphine and naltrexone, treating co-occurring serious mental illness in adults. Programs serve veterans, military families, forensic clients, and clients with HIV or AIDS. TRICARE, IHS/Tribal/Urban funds, and private insurance are accepted.

The Haven Detox
Sewell, NJ

Residential detoxification and short- and long-term residential treatment in Sewell, New Jersey, with transitional housing also offered. The Haven Detox uses buprenorphine and naltrexone and treats co-occurring disorders in adults, including veterans and trauma survivors. TRICARE accepted, a sliding fee scale is available, and Spanish is spoken.

Texoma Community Center

Located in Sherman, TX, Texoma Community Center provides targeted rehabilitation services for adults facing significant mental health issues alongside substance use disorders, as well as support for children with severe emotional challenges. The center features a range of programs including intensive outpatient care, regular outpatient services, and options for methadone/buprenorphine or naltrexone treatment. Emphasizing techniques such as 12-step guidance, anger management strategies, and brief interventions, the center serves a diverse clientele of adolescents, adult men, and women. Texoma Community Center is committed to delivering high-quality care to individuals of all ages and genders who are on the path to overcoming addiction and mental health difficulties.

Tennessee Valley Healthcare Services

Nestled in Murfreesboro, TN, Tennessee Valley Healthcare Services delivers a complete spectrum of care for adults and children battling addiction, substance abuse, and coinciding mental health challenges. This facility offers round-the-clock inpatient hospital services for detoxification, treatment, and ongoing support. They feature distinct programs designed for adult women, survivors of domestic abuse, and those who have faced sexual trauma. Employing proven methods such as cognitive behavioral therapy and the Matrix Model, the center emphasizes emotional regulation and complete well-being. Catering to adults and young adults irrespective of gender, Tennessee Valley Healthcare Services prioritizes personalized, superior treatment, positioning it as a premier destination for recovery.

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Saint Paul, MN

Situated in Saint Paul, MN, The Heights provides extensive treatment for substance use disorders, specifically designed for adult women, seniors, and young adults. The center focuses on dual diagnosis, addressing both substance use and significant mental health conditions. Offering options that range from short-term and long-term stays to round-the-clock residential care, The Heights employs validated treatment methods such as 12-step practices, cognitive behavioral therapy, and motivational interviewing. Additionally, the facility has specialized programs for individuals who have faced intimate partner violence, domestic violence, or sexual trauma. Committed to delivering tailored and effective care, The Heights is a reputable choice for individuals pursuing recovery and personal growth.

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Raleigh, NC

The Pines, situated in Raleigh, NC, delivers extensive treatment for adults facing substance use challenges along with significant mental health disorders, as well as support for children experiencing emotional difficulties. This center features a range of programs including intensive outpatient care, outpatient day services, and partial hospitalization options. The Pines also has specialized initiatives for active military personnel, teenagers, and victims of intimate partner abuse, addressing a variety of needs. Their customized treatment includes methods such as anger management, brief interventions, and cognitive behavioral therapy. With services for both men and women, this center is dedicated to providing exceptional care for those pursuing effective recovery solutions.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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