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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.

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Trilogy Inc
Chicago, IL

Trilogy Inc, located in Chicago, IL, provides an extensive array of outpatient services aimed at treating substance use issues and co-occurring mental health conditions in both adults and children. The center features specialized programs catering to adult women, trauma survivors, and those with dual diagnoses, ensuring care that meets the unique needs of a wide-ranging clientele. Trilogy Inc employs evidence-based methods such as 12-step facilitation, anger management techniques, and brief interventions, all aimed at promoting holistic recovery and sustained wellness. With a commitment to offering individualized support, the center serves clients of all genders and ages. Opt for Trilogy Inc for exceptional care and impactful treatment options in a supportive atmosphere.

Trinitas Regional Medical Center

Trinitas Regional Medical Center, located in Elizabethport, NJ, provides extensive rehabilitative support. Their expertise lies in addressing substance use issues and dual diagnoses for both younger and older individuals. Available treatment modalities encompass intensive outpatient, general outpatient, and partial hospitalization programs. Employing therapeutic strategies such as anger management, brief intervention, and cognitive behavioral therapy, this institution delivers personalized assistance to adult men, women, and survivors of domestic violence. Catering to adults and young adults across the gender spectrum, Trinitas Regional Medical Center is dedicated to delivering superior, customized care to foster healing and overall wellness.

Trinitas Regional Medical Center

Trinitas Regional Medical Center in Bayonne, NJ, delivers robust addiction treatment for adults and adolescents. Services include high-intensity outpatient therapy, standard outpatient services, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing skills like anger management, early intervention, and cognitive behavioral techniques, the center customizes care for each individual's unique journey. Dedicated programs are available for men, women, and individuals facing dual diagnoses of mental health and substance use issues. Welcoming both male and female clients, Trinitas Regional Medical Center fosters a nurturing atmosphere. The center is committed to providing effective care through diverse therapeutic methods to promote lasting recovery and overall wellness.

Tropical Texas Behavioral Health

Tropical Texas Behavioral Health, situated in Brownsville, TX, offers an extensive array of outpatient services aimed at those seeking help for addiction. This center is known for its detox programs, treatment for substance use disorders, and assistance for individuals dealing with concurrent substance use and serious mental health concerns, applicable to both adults and children experiencing significant emotional challenges. By employing various techniques, including cognitive behavioral therapy, anger management, and brief interventions, the facility provides customized support for active duty service members, teens, and adult males. With a commitment to delivering top-notch, gender-sensitive care, Tropical Texas Behavioral Health caters to both adult and youth populations across all genders to aid their recovery journey.

Tropical Texas Behavioral Health

Situated in Edinburg, TX, Tropical Texas Behavioral Health delivers a variety of outpatient services tailored for those aiming to overcome substance use disorders alongside mental health challenges. The center specializes in detoxification, treatment for substance use, and dedicated programs for active military personnel, teenagers, and adult males. Emphasizing evidence-based methodologies such as cognitive behavioral therapy and anger management, this facility serves clients of all ages and genders. From outpatient detox to methadone and buprenorphine therapies, the center emphasizes personalized care and holistic recovery, providing thorough support throughout each individual’s journey to wellness.

Trivium Life Services

Trivium Life Services in Boise, ID, provides extensive programs for individuals struggling with substance use and co-occurring mental health conditions, catering to both adults and young people. Their treatment modalities, including intensive outpatient, outpatient, and day treatment, utilize proven therapeutic methods such as cognitive behavioral therapy and anger management. The center features dedicated services for adult men and women, as well as those impacted by intimate partner or domestic violence. Trivium Life Services is committed to delivering individualized, high-caliber care to adults and young adults across the gender spectrum. For effective and customized addiction recovery in Boise, this facility stands out as an excellent option.

Trivium Life Services

Trivium Life Services, located in Caldwell, ID, specializes in rehabilitation programs for adults and seniors struggling with substance use disorders and concurrent mental health challenges. Their comprehensive outpatient and intensive outpatient programs use proven methods such as cognitive behavioral therapy and anger management strategies. This center caters to the unique needs of various groups, including active duty military members, adolescents, and adult males. Emphasizing personalized care, Trivium Life Services is committed to delivering effective treatment for individuals of all genders. Whether in need of outpatient methadone or buprenorphine services or short-term intervention programs, this facility is focused on guiding individuals toward recovery.

Tropical Texas Behavioral Health

Tropical Texas Behavioral Health, located in Weslaco, TX, provides a wide range of outpatient services aimed at detoxification, substance abuse, and concurrent mental health disorders for both adults and children. The facility focuses on personalized treatment through techniques such as anger management, brief interventions, and cognitive behavioral therapy to meet the unique needs of each individual. It offers specialized programs for active military personnel, youth, and adult males, ensuring that care is customized for various groups. Committed to delivering high-quality, evidence-informed care, Tropical Texas Behavioral Health serves individuals of all genders, emphasizing long-term recovery and overall wellness.

Triumph Treatment Services

Triumph Treatment Services in Yakima, WA, is dedicated to providing targeted substance abuse care for adult women managing co-occurring severe mental health conditions. The center offers residential and short-stay residential services incorporating methodologies like 12-step facilitation, anger control, and brief intervention strategies. A key feature of Triumph Treatment Services is its expertise in supporting individuals with histories of intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, older adults, and young adults, this facility ensures a secure and nurturing setting exclusively for women. Patients can anticipate empathetic and thorough treatment at Triumph Treatment Services.

Tropical Texas Behavioral Health

Tropical Texas Behavioral Health, situated in Harlingen, TX, presents a wide array of outpatient services aimed at assisting individuals in their recovery from substance use issues and related mental health disorders. The center features specialized programs tailored for active military personnel, adolescents, and adult men, ensuring that treatment is customized for all genders, including both adults and youth. By employing evidence-based methods like cognitive behavioral therapy and anger management, this facility is dedicated to providing exceptional care through outpatient detox services, substance use programs, and therapies such as methadone/buprenorphine or naltrexone. Individuals can access both short-term and extended care options, with the assurance of personalized treatment strategies to aid in their recovery at Tropical Texas Behavioral Health.

Troyer Medical
Landis, NC

Troyer Medical in Landis, North Carolina, provides outpatient substance use treatment with buprenorphine and naltrexone. Children, adolescents, adults, and seniors are served, including veterans, pregnant and postpartum women, and clients with co-occurring pain and substance use disorders. Medicare, Medicaid, and TRICARE are accepted. Sign language services are available.

TruHealing Baltimore

TruHealing Baltimore in Gwynn Oak, MD, runs residential detoxification and short-term residential substance use treatment with buprenorphine and naltrexone. Programs serve adult women and men, criminal justice clients, and trauma survivors. Medicare, Medicaid, private insurance, and self-payment are accepted.

Trinity Behavioral Care

Situated in Mullins, SC, Trinity Behavioral Care delivers a wide range of services for substance use rehabilitation. The center specializes in intensive outpatient programs, standard outpatient care, and offers medication-assisted treatment options including methadone, buprenorphine, and naltrexone. Utilizing methods such as anger management, cognitive behavioral therapy, and community reinforcement with vouchers, Trinity addresses the unique needs of its clients. It also features special programs designed for active military personnel, teenagers, and adult men. Catering to both adults and youth, the center provides personalized treatment plans for males and females alike. With an emphasis on high-quality, individualized care, Trinity Behavioral Care is recognized as a reliable option for those seeking recovery from addiction.

Trinity Behavioral Care

Trinity Behavioral Care, located in Dillon, SC, provides a wide range of substance use disorder treatment programs designed to meet the specific needs of each individual. The center offers intensive outpatient services, as well as outpatient alternatives, including methadone, buprenorphine, and naltrexone treatments. Emphasizing holistic recovery, the center incorporates anger management techniques, cognitive behavioral therapy, and a community reinforcement approach with vouchers to support clients. Unique programs are available for active duty military members, adolescents, and adult males, while also accommodating adults and children/adolescents across all genders. The dedication of Trinity Behavioral Care to delivering high-quality care and a variety of services solidifies its reputation as a reliable option for those in need of effective addiction treatment.

Trilogy Center for Women
Hopkinsville, KY

Trilogy Center for Women, situated in Hopkinsville, KY, specializes in long-term residential treatment for substance use disorders specifically designed for adult women. This center offers various housing solutions, including transitional and sober living options, all within a nurturing atmosphere. Their treatment methodology employs a 12-step facilitation model with an emphasis on customized care plans. Catering to diverse groups such as seniors and young adults, Trilogy Center for Women delivers a thorough and specialized approach to treatment. The center is distinguished by its dedication to empowering women on their journey to sustained recovery through a tailored residential program.

Tru Luv Management
Baltimore, MD

Tru Luv Management, located in Baltimore, MD, provides comprehensive rehabilitation programs for adult males facing substance dependency and co-occurring severe mental health conditions. This facility offers diverse treatment durations, including extended stays, shorter programs, and round-the-clock residential care, employing proven therapeutic methods such as 12-step support, motivational interviewing, and cognitive behavioral techniques. Featuring tailored services for active military personnel, young adults, and adult men, Tru Luv Management is dedicated to fostering a nurturing and disciplined setting for healing. Their approach centers on customized support, aiming to guide individuals toward sustained recovery and improved mental well-being.

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Trinity Addiction Services, located in Minot, ND, provides a wide range of addiction recovery programs aimed at both adults and young adults. The center features inpatient detoxification and treatment options, including dedicated programs for active duty military members, as well as separate services for adult men and women. Utilizing methods such as 12-step facilitation, anger management, and cognitive behavioral therapy, Trinity Addiction Services emphasizes individualized care to foster successful recovery journeys. Catering to both genders, the facility creates a nurturing atmosphere for those looking to overcome substance use challenges. Renowned for its high-quality care and customized treatment plans, Trinity Addiction Services stands as a guiding light for individuals pursuing a sober lifestyle.

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Trinity Health Ann Arbor, located in Ann Arbor, MI, provides a wide range of specialized programs for individuals seeking treatment for substance use disorders. The center features intensive outpatient programs, standard outpatient services, and options for outpatient methadone, buprenorphine, or naltrexone treatment. Employing evidence-based methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the facility serves adult men and women, including those who have faced intimate or domestic violence. With a strong focus on adults and young adults, Trinity Health Ann Arbor is dedicated to offering personalized care for both male and female clients, prioritizing effective treatment and support for individuals on their path to recovery from addiction.

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Long Beach, NY

Triumph Treatment LLC, located in Long Beach, NY, provides outpatient services aimed at aiding adults and young adults facing substance use issues alongside significant mental health challenges. This center features tailored programs designed for those who have suffered trauma, employing methods like 12-step support, anger management strategies, and brief interventions. Additionally, Triumph Treatment LLC offers outpatient services for methadone/buprenorphine or naltrexone. The facility serves both male and female clients, promoting a thorough and inclusive pathway to recovery. Committed to delivering high-quality care and personalized treatment strategies, this center is devoted to assisting clients in their pursuit of sobriety and improved mental health.

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Triumph Treatment Services, located in Buena, WA, provides targeted substance use rehabilitation within a residential framework specifically designed for adult males. Their offerings encompass 12-step programs, brief intervention techniques, and cognitive behavioral therapy. This center is equipped to offer short-term residential support for individuals grappling with issues stemming from sexual abuse or other traumatic experiences. Catering to adults, seniors, and young adults, Triumph Treatment Services prioritizes personalized care for male clients on their recovery journey. With a dedication to delivering high-quality treatment and distinct programs, this center stands out as a nurturing option for those aiming to confront substance use disorders in a caring atmosphere.

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Troy, NY

Situated in Troy, NY, Troy House is a dedicated rehabilitation center aimed at helping adult men battling substance use disorders. It offers a range of programs, including long-term, short-term, and 24-hour residential options, all based on proven methodologies such as cognitive behavioral therapy and anger management strategies. What sets Troy House apart is its emphasis on treating individuals with simultaneous mental health challenges and those involved in the legal system. Designed specifically for adult and young adult males, the center provides exceptional care through various housing solutions, including transitional living and sober homes. For those looking for a nurturing setting for substance use recovery and reintegration, Troy House is committed to supporting your path to healing.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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