Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.
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Situated in Perry Point, MD, the VA Maryland Healthcare System provides an extensive array of services aimed at addressing substance use disorders, transitional living, and co-existing mental health issues for both adults and children. This center offers both outpatient and residential treatment options, employing specialized methods that include 12-step processes, anger management strategies, and short-term interventions. Aimed particularly at clients who have faced trauma, dual diagnoses, and veterans, the center serves adults and young adults of all genders. With its commitment to high-quality care and customized treatment plans, this facility stands out as an excellent choice for those in need of effective and empathetic rehabilitation services.
The VA Maryland Healthcare System, located in Baltimore, MD, provides extensive recovery support for individuals, including young adults, struggling with addiction and related mental health challenges. Their services include medically supervised detoxification and inpatient care, utilizing therapeutic strategies like anger management techniques, brief intervention counseling, and cognitive behavioral therapy. Dedicated programs are available for active military personnel, adult men, and women, addressing their specific requirements. The facility's commitment to high-standard treatment and personalized recovery pathways is designed to offer patients the necessary assistance for enduring well-being.
The VA Med/Jonathan M Wainwright Mem center, situated in Walla Walla, WA, provides outpatient services for substance use disorders, emphasizing the treatment of adults with co-occurring serious mental health conditions and emotional issues in children. The center employs various therapeutic techniques, including anger management, cognitive behavioral therapy, and motivational interviewing, to deliver tailored care for veterans. This facility is committed to serving individuals of all ages and genders with outpatient options for methadone, buprenorphine, or naltrexone treatment. With a strong focus on personalized care and supporting individuals in their recovery journey, this center stands out in its quality of services.
Situated in Marion, IN, the VA Northern Indiana Healthcare System delivers extensive addiction treatment options for both adults and young adults. The facility is adept in detoxification, managing substance use issues, and addressing co-occurring mental health conditions. It features hospital inpatient services that emphasize 12-step processes, anger management strategies, and brief intervention techniques. With dedicated programs for veterans and services catering to all genders, the center is committed to providing excellent care for those on the path to recovery from substance abuse. It creates a nurturing atmosphere aimed at facilitating healing and personal development, whether addressing addiction or mental health challenges.
The VA Northern Indiana Healthcare System in Fort Wayne, IN, provides dedicated rehabilitation programs for individuals, encompassing adults and young adults, who are navigating the complexities of substance use disorders alongside co-occurring mental health challenges. Their offerings include structured intensive outpatient treatment, services for outpatient detoxification, and general outpatient care. Therapeutic modalities employed include 12-step facilitation, anger management techniques, and brief intervention strategies. The center is committed to delivering high-quality, personalized care specifically designed for veterans, offering robust support for both male and female patients. For those in search of scientifically supported treatment within a nurturing setting, this establishment represents a strong option for successful recovery.
The VA NY Harbor Healthcare System located in New York, NY offers a wide range of rehabilitation services aimed at supporting adults and young adults facing challenges from substance use disorders alongside mental health issues. The facility provides inpatient detoxification and treatment options, employing evidence-based methodologies such as 12-step support, anger management, and short counseling sessions. Specialized programs are available for adult men, adult women, and those who have faced sexual trauma. With an emphasis on personalized care, this center fosters a nurturing setting conducive to recovery. Programs designed specifically for men and women contribute to the success of individuals working to defeat addiction.
The VA Pittsburgh Healthcare System, situated in Pittsburgh, PA, offers an extensive array of outpatient services aimed at detoxification, treatment for substance use, and management of co-occurring disorders for both adults and children. This center is particularly dedicated to veterans, providing outpatient detox options as well as methadone and buprenorphine therapies. Emphasizing 12-step programs, anger management, and brief interventions, the facility serves both male and female adults, including young adults, who are looking for effective solutions for addiction and mental health issues. For veterans and civilians alike, this center may present an excellent opportunity for a supportive rehabilitation experience.
Located in Vancouver, WA, the VA Portland Healthcare System provides a wide array of services aimed at adults and seniors dealing with substance use issues alongside mental health challenges. The facility emphasizes intensive outpatient programs and detoxification services for those who need them. It specializes in care for adult women, trauma survivors, and individuals facing multiple disorders. The treatment methods utilized include 12-step facilitation, brief interventions, and cognitive behavioral therapy, all of which are designed to address the specific requirements of each client. The VA Portland Healthcare System is dedicated to delivering high-quality care, making it a reliable choice for people in search of addiction support and mental health assistance.
The VA Puget Sound Healthcare System, situated in Tacoma, WA, delivers extensive recovery programs for adults and young adults struggling with addiction and related mental health challenges. Their offerings include intensive outpatient care, outpatient detox, and general outpatient services, all grounded in proven methods like cognitive behavioral therapy and contingency management. The center also features specialized tracks for adult men, adult women, and individuals with a history of trauma. Committed to high-quality, personalized treatment, this facility accommodates both male and female patients, fostering a nurturing atmosphere for those on their path to wellness.
The VA Puget Sound Healthcare System, situated in Seattle, WA, delivers extensive substance abuse recovery programs for individuals of all ages. This institution offers tailored assistance for withdrawal management, addiction therapy, and concurrent mental health challenges. Services encompass inpatient hospital detox, structured outpatient programs, and round-the-clock hospital-based inpatient treatment. Employing research-backed methods like cognitive behavioral therapy and contingency management, the facility serves adult men and women, as well as survivors of sexual abuse. Its dedication to personalized care and high-standard rehabilitation makes it a premier destination for those pursuing successful recovery.
Situated in Roseburg, OR, the VA Roseburg Healthcare System delivers extensive programs for substance use recovery. This center features outpatient services such as methadone/buprenorphine or naltrexone therapy, standard outpatient sessions, and short-term interventions. The facility emphasizes cognitive behavioral therapy and motivational interviewing techniques. It also provides tailored programs for individuals who have faced trauma, including veterans. Adults and young adults of all genders can access high-quality care and specialized services offered here. If you or someone you know is in search of effective addiction treatment, the VA Roseburg Healthcare System is a commendable choice for customized, evidence-supported care.
The VA NY Harbor Healthcare System located in Brooklyn, NY, provides diverse treatment solutions for adults dealing with substance use issues and concurrent serious mental health disorders, as well as emotional challenges faced by children. The center features a variety of programs, including intensive outpatient services, long-term residential care, and traditional outpatient treatment, employing methodologies like 12-step programs, anger management techniques, and brief intervention strategies. It also offers specialized services for adult men, women, and individuals who have suffered from sexual abuse. This facility serves both adult and young adult populations, delivering personalized care with an emphasis on high-quality, evidence-based interventions.
Short-term residential substance use treatment for veterans is provided at this VA community-based outpatient clinic in Grand Island, Nebraska. Buprenorphine and naltrexone are used in treatment. The program serves young adults, adults, and seniors, and no payment is accepted for services.
The VA NJ Healthcare System in East Orange, New Jersey provides veterans with detoxification, short-term residential care, intensive outpatient treatment, and transitional housing, with buprenorphine and naltrexone used in treatment. Government funding covers services, and payment assistance is available for eligible patients.
The Chico outpatient clinic of VA Northern California Health Care System provides substance use treatment with buprenorphine and naltrexone for veterans from young adults through seniors, including those with co-occurring mental health disorders, chronic pain, HIV or AIDS, and trauma. TRICARE, Medicare, and federal funding are accepted.
Veterans in Redding, CA can access outpatient substance use treatment at this VA Northern California Health Care System clinic, which uses buprenorphine and naltrexone. The program also serves adult men and women, seniors, and clients with co-occurring disorders or trauma. Medicare, TRICARE, and private insurance are accepted.
Operated by the San Francisco VA Healthcare System, VA Oakland Behavioral Health Clinic provides outpatient substance use treatment in Oakland, California with methadone, buprenorphine, and naltrexone. It focuses on veterans, including those with trauma histories, co-occurring mental health disorders, and chronic pain. TRICARE is accepted.
Veterans and military families receive outpatient substance use treatment at the VA Palo Alto Healthcare System's San Jose clinic, with buprenorphine and naltrexone available. Programs also serve pregnant and postpartum women, criminal justice clients, and people with HIV or AIDS. Services are offered in Spanish, Chinese, Vietnamese, and sign language.
The VA Palo Alto Healthcare System's Monterey clinic in Marina, California, offers outpatient substance use treatment with buprenorphine and naltrexone for veterans, active duty military, and military families. Clients with co-occurring pain, trauma histories, or HIV or AIDS are also served. Services are available in Spanish and Tagalog.
Veterans in the Scottsbluff, Nebraska area can receive outpatient substance use treatment with buprenorphine and naltrexone at this VA community clinic. Programs address co-occurring mental health disorders and trauma, and serve adult women, men, and seniors. Federal funding, Medicare, Medicaid, and private insurance are accepted.
Veterans in Bend, Oregon can access outpatient substance use treatment at this VA Portland Health Care System clinic, including buprenorphine and naltrexone treatment and care for co-occurring serious mental illness. Programs serve veterans and clients who have experienced trauma, from young adults through seniors.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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