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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Boulevard Recovery Center

Situated in Tonawanda, NY, Boulevard Recovery Center provides a wide range of treatment options for adults dealing with substance use disorders and co-occurring mental health conditions. The facility features intensive outpatient care, outpatient services, and targeted outpatient treatment options such as methadone/buprenorphine or naltrexone therapy. Emphasizing 12-step programs, anger management, and brief intervention techniques, this center supports active duty military members, adolescents, and adult males. Boulevard Recovery Center is committed to helping adults, children, adolescents, and young adults of all genders, offering individualized programs aimed at fostering enduring recovery and overall well-being.

Bowery Residents Committee Inc

Situated in New York, NY, Bowery Residents Committee Inc delivers a wide array of treatment options for substance use, with a focus on managing co-occurring disorders for both adults and children. The facility offers intensive outpatient programs alongside various outpatient services, including methadone/buprenorphine and naltrexone therapies. Their treatment strategy incorporates techniques such as anger management, brief interventions, and cognitive behavioral therapy. Bowery Residents Committee Inc is dedicated to providing specialized programs for adult men and women, as well as clients facing co-occurring challenges, serving individuals of diverse backgrounds. Patients can look forward to personalized care and customized treatment plans that foster their path to recovery.

Bradford Health Services

Situated in Warrior, AL, Bradford Health Services provides extensive addiction rehabilitation programs for both adults and young adults. This center is well-equipped for hospital inpatient detox and treatment, offering around-the-clock support for those in need of recovery from substance use issues. Emphasizing the 12-step approach, anger management, and brief therapeutic interventions, the facility serves a diverse clientele of men and women. It also features specialized programs designed for active-duty military members and distinct offerings for adult men and women, ensuring customized assistance for various groups. Bradford Health Services strives to provide exceptional care and individualized treatment plans to facilitate long-term sobriety for individuals.

Bradford Health Services

Bradford Health Services in Madison, AL, delivers thorough addiction recovery services, encompassing detox and treatment for substance dependence. Their specialized hospital inpatient care, available around the clock, fosters a nurturing atmosphere for adults and young adults. The center employs scientifically validated methods, including 12-step support, emotional regulation techniques, and short-term counseling, to meet each person's specific requirements. Distinctive programs are designed for active military members, adult men, and adult women. Committed to high standards of care, Bradford Health Services crafts individualized recovery paths for male and female clients aiming to conquer addiction.

Boston Public Health Commission

Situated in Mattapan, MA, the Boston Public Health Commission delivers extensive treatment options for substance use, specifically designed for adult women. This center offers an array of services including hospital inpatient treatment, around-the-clock care, and extended residential programs. Implementing proven methodologies such as 12-step facilitation, cognitive behavioral therapy, and anger management, the facility is dedicated to helping those who have faced intimate partner violence, domestic abuse, and sexual trauma. Emphasizing support for adult women, seniors, and young adults, the center fosters a nurturing atmosphere for those pursuing effective rehabilitation.

Borinquen Medical Centers

Borinquen Medical Centers, situated in Miami, FL, provides holistic treatment options for substance use disorders, specifically addressing co-occurring mental health issues in both adults and children. The center features a range of services, including intensive outpatient programs, general outpatient care, and treatment options involving methadone, buprenorphine, or naltrexone. Emphasizing cognitive behavioral therapy, anger management techniques, and brief therapeutic interventions, this facility is equipped to support individuals who have experienced trauma, are living with HIV/AIDS, or require dual diagnosis treatment. Catering to adults and young adults of all genders, Borinquen Medical Centers focuses on creating a personalized care approach, ensuring a nurturing environment conducive to recovery and personal growth.

BPHC Substance Abuse Prevention and

The BPHC Substance Abuse Prevention and center, situated in Boston, MA, delivers extensive outpatient care for individuals battling substance use disorders. They are particularly adept at addressing co-occurring mental health challenges in adults and emotional difficulties in children. Services include outpatient treatment with methadone, buprenorphine, and naltrexone. Their therapeutic approach incorporates anger management, brief intervention strategies, and cognitive behavioral therapy. The program is designed to assist adolescents and adults, encompassing both men and women, and accepts patients of all genders. This facility is committed to providing high-standard care and tailored programs to aid individuals in their recovery journey.

Bradford Health Services

Situated in Cookeville, TN, Bradford Health Services delivers extensive treatment options for substance use disorders for both adults and young people. This center offers intensive outpatient programs, general outpatient services, and medication-assisted treatment such as methadone, buprenorphine, or naltrexone. Designed to meet the needs of various groups, Bradford Health Services includes specialized programs for adolescents, men, and women. The facility employs methods like 12-step support, anger management sessions, and brief interventions to aid individuals on their recovery journey. Their gender-specific initiatives provide personalized care for men and women alike. Clients can anticipate receiving high-quality, research-supported treatment within a nurturing environment that promotes enduring recovery.

Bradford Health Services

Bradford Health Services, located in Huntsville, Alabama, specializes in providing targeted treatment for substance use disorders in both adults and teenagers. The center features various programs including intensive outpatient therapy, general outpatient care, and treatments utilizing methadone, buprenorphine, or naltrexone in an outpatient setting. Employing evidence-driven strategies such as 12-step support, anger management sessions, and brief interventions, the facility serves adult men, adult women, and youths. Emphasizing personalized treatment plans, Bradford Health Services is dedicated to delivering high-quality care to all clients. If you are searching for thorough addiction treatment in a nurturing atmosphere, this Huntsville facility is recognized for its customized offerings and dedication to fostering recovery.

Bradford Health Services

Bradford Health Services in Nashville, TN, provides a full spectrum of addiction recovery services for both young people and adults. Their offerings include intensive outpatient care, standard outpatient services, and day treatment or partial hospitalization programs. The center employs methods like 12-step facilitation, anger management techniques, and brief intervention strategies to create individualized care plans. Specific programs are designed for adolescents, adult men, and adult women. Prioritizing excellent care and personalized recovery, Bradford Health Services is equipped to assist male and female individuals looking for effective and supportive addiction treatment.

BornFree Wellness Centers of America

Situated in Germantown, MD, BornFree Wellness Centers of America provides extensive outpatient treatment for both adults and young adults dealing with substance use issues. This center is adept at addressing co-occurring mental health disorders and severe emotional challenges in children. The program is built on proven methods, including cognitive behavioral therapy, motivational interviewing, and contingency management. BornFree Wellness Centers of America serves both men and women, offering tailored support for those with overlapping mental health and substance misuse disorders. Emphasizing personalized treatment and high-quality care, the center is committed to guiding clients toward sustainable recovery.

Boulder Integrated Health

Boulder Integrated Health, situated in Boulder, CO, provides an extensive selection of rehabilitation services aimed at both adults and young adults. This facility concentrates on treating substance use issues and co-occurring disorders, offering both intensive outpatient and outpatient programs that incorporate techniques like 12-step facilitation and anger management. Prioritizing high standards of care, Boulder Integrated Health serves active duty military members, as well as adult men and women. The center also features transitional housing and sober living arrangements. With personalized treatment plans and a nurturing atmosphere, it stands out as an excellent option for those in search of comprehensive and effective rehabilitation support.

Bradford Health Services

Bradford Health Services, located in Mobile, AL, specializes in treating substance use disorders with a focus on intensive outpatient, outpatient, and programs utilizing methadone, buprenorphine, or naltrexone. The center employs methods such as 12-step facilitation, anger management, and brief intervention to meet the unique needs of each individual. Catering to both adult men and women, as well as services tailored for young adults, the facility is dedicated to providing personalized care for a variety of populations. Bradford Health Services is committed to offering high-quality, gender-sensitive treatment options. For those looking for thorough addiction recovery support in Mobile, this center provides an encouraging atmosphere that promotes healing and well-being.

Bradford Health Services

Bradford Health Services, situated in Chattanooga, TN, provides targeted treatment for substance use issues among adults and teens. The facility features a range of options including intensive outpatient programs, standard outpatient services, and medication-assisted treatments with methadone or buprenorphine and naltrexone. Emphasizing methodologies such as 12-step support, anger management, and brief intervention strategies, Bradford Health Services accommodates both adult males and females, in addition to adolescents. The center is committed to offering personalized care tailored to the distinct requirements of each individual, fostering a nurturing and welcoming atmosphere for all pursuing recovery from addiction.

Bradford Health Services

Bradford Health Services in Birmingham, AL, is a dedicated facility providing tailored recovery pathways for adult men, adult women, and young adults struggling with addiction. They offer comprehensive outpatient services, including intensive programs and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The therapeutic framework at Bradford Health Services utilizes proven methods like 12-step support, anger management techniques, and brief intervention strategies to foster lasting sobriety. Recognizing the unique needs of each individual, this center fosters a welcoming and affirming atmosphere for all clients, both male and female. Bradford Health Services commits to delivering superior substance use disorder rehabilitation for adults and young adults on their journey to recovery.

Bradford Health Services

Bradford Health Services, located in Manchester, TN, is dedicated to providing tailored substance use recovery solutions for both adults and teenagers. The facility specializes in intensive outpatient programs, standard outpatient services, and both methadone/buprenorphine and naltrexone treatments. Emphasizing 12-step support, anger management techniques, and brief intervention strategies, the center addresses the distinct requirements of adult men, adult women, and adolescents. With offerings for individuals of all genders, Bradford Health Services is committed to delivering thorough care to those striving to overcome substance use challenges. Its high-quality services and focused programs make it a significant option for individuals seeking effective, customized addiction recovery assistance.

Bradford Health Services

Bradford Health Services, located in Florence, AL, delivers a wide range of treatment options for substance use, customized to meet the specific needs of individuals. This center specializes in intensive outpatient programs, general outpatient services, and treatments involving methadone, buprenorphine, or naltrexone on an outpatient basis. Emphasizing 12-step methods, anger management strategies, and brief interventions, the facility serves adult men and women, along with young adults. The programs are structured to tackle the distinct challenges that different genders encounter, ensuring a tailored approach to care and support. Bradford Health Services in Florence maintains exceptional care standards, making it a reliable option for those in need of effective and empathetic addiction recovery services.

Bradford Health Services

Bradford Health Services in Montgomery, AL, provides a wide range of substance abuse treatment options designed to meet personal requirements. This center offers intensive outpatient programs, standard outpatient care, and specific treatments involving methadone, buprenorphine, or naltrexone. Emphasizing methods such as 12-step support, anger management, and short intervention strategies, the facility serves adult men and women, along with young adults. Its targeted programs for varied age groups and genders allow for individualized treatment and support. Bradford Health Services in Montgomery is committed to providing top-notch and effective rehabilitation solutions for individuals seeking assistance with substance use issues.

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Situated in Miami, FL, Borinquen Behavioral Health Center specializes in providing targeted substance abuse treatment for adults and young adults dealing with simultaneous mental health challenges. This center offers a range of services including intensive outpatient programs, outpatient services, and treatments incorporating methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, Borinquen customizes its treatment plans to meet the specific requirements of each client. The center features distinctive programs designed for individuals who have endured trauma, those living with HIV or AIDS, and people facing co-occurring disorders. Borinquen Behavioral Health Center is dedicated to delivering high-quality rehabilitation care for both male and female individuals seeking comprehensive support.

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Fort Wayne, IN

Bowen Health Clinic located in Fort Wayne, IN, specializes in rehabilitation for individuals facing substance use issues alongside mental health challenges. The clinic offers various treatment formats, including intensive outpatient programs, standard outpatient services, and medication-assisted therapies using methadone, buprenorphine, or naltrexone. Emphasizing strategies such as anger management, brief interventions, and cognitive behavioral therapy, the clinic serves a diverse clientele that includes adult males, teenagers, and military personnel. Catering to adults and older individuals of any gender, Bowen Health Clinic provides customized support to assist individuals in their recovery process with care and empathy.

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Boxwood Detox and Recovery Program, located in Culpeper, VA, specializes in offering thorough solutions for detox and substance use challenges. The facility features inpatient medical services along with round-the-clock support, creating a secure and nurturing atmosphere for individuals on their path to recovery. Their approach includes methods such as 12-step facilitation, anger management, and targeted brief interventions to meet specific needs. Additionally, the center provides tailored programs for active duty military members, as well as separate tracks for adult men and women, addressing a variety of demographic factors. Catering to adults and young adults of every gender, this center emphasizes high-quality care and a comprehensive strategy for treating addiction. Boxwood Detox and Recovery Program is recognized for its individualized treatment plans and dedication to enabling individuals to attain enduring recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)