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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.

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Virginia Hospital Center

Virginia Hospital Center, located in Arlington, VA, delivers extensive addiction recovery services for both adults and young adults. The facility focuses on detoxification and treatment for substance use disorders while also addressing the needs of individuals with concurrent severe mental health conditions. Prioritizing high-quality care, the center provides inpatient detox and treatment within a hospital environment. It employs various therapeutic methods, such as 12-step programs, anger management strategies, and brief intervention techniques, catering to all patients, including targeted services for active duty military personnel, as well as adult men and women. For those seeking specialized support in addiction recovery, this center offers customized programs designed to facilitate healing.

Virginia Hospital Center

Virginia Hospital Center in Arlington, VA, provides a complete recovery journey for those facing addiction. Their services encompass safe detoxification, extensive addiction treatment, and targeted support for adults with co-occurring mental health and substance use issues, as well as children experiencing emotional difficulties. The center offers various levels of care, including intensive outpatient programs, standard outpatient services, and outpatient detoxification. Patients benefit from evidence-based therapies such as 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Recognizing that each person's path to wellness is unique, their programs are designed for adults and young adults across the gender spectrum, delivering excellent care for everyone committed to their recovery.

Virtue At The Pointe Recovery

Virtue At The Pointe Recovery in Astoria, OR, provides complete drug and alcohol withdrawal management along with addiction treatment within a hospital inpatient environment. Their offerings include unique methods like 12-step program support, strategies for managing anger, and brief counseling interventions. This center delivers customized support for adults and young adults of any gender, with specific programs designed for those who have endured sexual abuse, trauma, or who struggle with co-occurring mental health and addiction issues. Emphasizing personalized treatment strategies and scientifically proven methods, Virtue At The Pointe Recovery is committed to delivering excellent care to assist individuals on their journey toward healing.

Virtue Center
Norman, OK

Situated in Norman, OK, the Virtue Center provides targeted programs for substance use recovery in an outpatient format. The center features intensive outpatient care, general outpatient services, and specialized treatment options using medications like methadone, buprenorphine, or naltrexone. Employing techniques such as anger management, brief interventions, and cognitive behavioral therapy, the facility serves adolescents as well as adult men and women. The Virtue Center is dedicated to offering personalized quality care to adults and seniors, regardless of gender. If you're looking for thorough addiction recovery in a nurturing setting, this center presents a variety of programs aimed at fostering enduring healing.

Virtue Recovery Center Chandler

Nestled in Chandler, AZ, Virtue Recovery Center Chandler is a leading establishment providing a full spectrum of addiction recovery solutions. Their offerings encompass detox, comprehensive substance use therapy, supportive transitional housing, and structured sober living environments. Addressing diverse needs, they offer intensive outpatient, long-term residential, and outpatient treatment modalities, serving adults and young adults irrespective of gender. Virtue Recovery Center Chandler excels in therapeutic approaches such as 12-step facilitation, anger management, and brief intervention strategies. They also feature specialized programs designed for adult men, adult women, and individuals grappling with trauma. The center is celebrated for its high standards of care and bespoke recovery journeys crafted for each client.

Village South Inc

Village South Inc, situated in Miami, FL, is a premier facility dedicated to providing outpatient care for adults struggling with substance use and co-occurring serious mental health issues. They have a particular focus on adolescent treatment, employing proven methods like 12-step facilitation and cognitive behavioral therapy. Village South Inc also provides medication-assisted treatment options, including methadone, buprenorphine, or naltrexone. Their approach emphasizes community reinforcement and voucher programs, serving both male and female individuals who require integrated support for addiction and mental health challenges. Discover effective treatment and dedicated assistance at Village South Inc.

Vinland National Center

Situated in Loretto, MN, Vinland National Center specializes in treating adult males dealing with substance use disorders alongside significant mental health challenges. The facility offers residential services in a nurturing setting, employing proven methods including 12-step programs, anger management techniques, and short-term interventions. Vinland National Center is dedicated to serving active duty military members, adult men, and survivors of intimate partner violence. By emphasizing personalized treatment for adults, seniors, and young adults, the center strives to deliver effective rehabilitation solutions tailored to individual needs.

Village for Families and Children

Situated in Hartford, CT, the Village for Families and Children delivers a variety of focused treatment programs designed to tackle substance use issues and dual mental health challenges in both adults and children. Offering both intensive outpatient and outpatient services, the center includes treatment options like methadone, buprenorphine, and naltrexone. Care is customized using research-backed strategies such as 12-step support, anger management, and brief interventions. Specialized programs for active duty service members and distinct services for adult men and women enhance the treatment's impact. Catering to individuals of all genders, the facility emphasizes high-quality care and assistance for those striving for recovery from addiction.

Village for Families and Children

The Village for Families and Children, situated in Hartford, CT, provides expert care for substance abuse and dual diagnoses in both adults and youth. Their robust outpatient services include support for the 12-step approach, strategies for managing anger, and concise intervention techniques. Dedicated programs cater to active-duty military personnel, as well as men and women. The center administers outpatient treatment using methadone, buprenorphine, or naltrexone. Committed to high standards of care, this establishment supports adults and young adults across all gender identities, promoting a holistic path to recovery. For those in search of understanding and successful treatment, the Village for Families and Children is a notable option.

Vin Baker Recovery
Milwaukee, WI

Vin Baker Recovery in Milwaukee, WI, delivers regular and intensive outpatient treatment with methadone, buprenorphine, and naltrexone for opioid use disorder, plus care for adults with co-occurring serious mental illness. Medicaid, private insurance, self-payment, and federal funding are accepted, and Spanish-language services are offered.

Virginia Beach Psychiatric Center

The Virginia Beach Psychiatric Center, situated in Virginia Beach, VA, delivers extensive treatment options for adults and children facing addiction and accompanying mental health challenges. This institution provides inpatient hospital detox and care, featuring distinct programs for adult males, adult females, and survivors of sexual trauma. Emphasizing 12-step engagement, short-term intervention, and methods to avoid relapse, the center serves adults, seniors, and young adults of any gender. The Virginia Beach Psychiatric Center is committed to offering superior care and assistance to guide individuals toward sustained healing.

Virginia Recovery Centers
Mechanicsville, VA

Virginia Recovery Centers in Mechanicsville, Virginia, covers outpatient detoxification, partial hospitalization, intensive outpatient, and regular outpatient care, with buprenorphine and naltrexone for opioid use disorder. Programs serve pregnant women, veterans, criminal justice clients, and people with co-occurring mental illness or chronic pain. Medicaid and private insurance are accepted.

Virtue Detox LLC
Sun City West, AZ

Hospital-based inpatient detoxification in Sun City West, Arizona, is the focus of Virtue Detox LLC, which uses buprenorphine and naltrexone during withdrawal management. The program serves adults and seniors, including veterans, active duty military, and clients with co-occurring mental or pain disorders. Medicaid and private insurance are accepted.

Virtue Health and Wellness LLC

Baltimore, Maryland is home to Virtue Health and Wellness LLC, an outpatient clinic offering day treatment, intensive outpatient care, and medication treatment with buprenorphine or naltrexone. Special programs serve adolescents, pregnant women, veterans, and military families. Payment options include Medicaid, TRICARE, SAMHSA block grants, and a sliding fee scale, and Spanish-language services are available.

Virtue Recovery Center

Virtue Recovery Center in Killeen, Texas, offers hospital inpatient detox, residential detox, long- and short-term residential care, partial hospitalization, and intensive outpatient treatment with buprenorphine and naltrexone, plus sober housing. Programs serve veterans and military families. Medicaid, TRICARE, and tribal funds are accepted.

Virtue Recovery Houston

Virtue Recovery Houston in Houston, Texas offers residential detoxification and short-term residential treatment for substance use and co-occurring serious mental illness. Buprenorphine and naltrexone are used in treatment, with programs for veterans, military families, and trauma survivors. Payment is by private health insurance or self-pay.

Villas at Bryn Mawr Outpatient

Day treatment and intensive outpatient care in Minneapolis, Minnesota, for adult men with substance use and co-occurring mental health disorders. Buprenorphine and naltrexone are used in treatment. Programs serve veterans, active duty military, forensic clients, and people with HIV or AIDS. Medicaid, federal funding, private insurance, and self-payment are accepted.

Virtue Care Services Inc

Adolescents through seniors can access partial hospitalization, intensive outpatient, and regular outpatient treatment at this Edison, New Jersey provider, which uses buprenorphine and naltrexone and treats co-occurring disorders in adults and children. Medicare, Medicaid, SAMHSA block grants, and a sliding fee scale are accepted, with services in Spanish, Creole, and Hindi.

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Ville Platte Behavioral Health, situated in Ville Platte, LA, provides outpatient services for individuals of all ages grappling with substance abuse and accompanying mental health challenges. Their therapeutic approach emphasizes 12-step program integration, techniques for managing anger, and concise intervention strategies. The center features distinct programs designed for teenagers, adult males, and adult females. They are committed to delivering personalized, high-quality care to every client, irrespective of gender, aiming to foster lasting recovery and enhance overall health.

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Vinfen Behavioral Health in Lowell, Massachusetts, treats substance use and co-occurring disorders in children, adolescents, and adults through outpatient care with buprenorphine and naltrexone. Programs serve veterans, pregnant women, and clients with HIV or AIDS. Medicaid, Medicare, and a sliding fee scale apply, with Spanish and Creole spoken.

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Regular outpatient treatment for substance use and co-occurring serious mental illness is provided by Vinfen Behavioral Health in Lawrence, Massachusetts, with buprenorphine and naltrexone used in care. Clients range from adolescents to seniors, including veterans, pregnant women, and forensic clients. Medicare, Medicaid, private insurance, and a sliding fee scale are accepted. Spanish and sign language services.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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