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Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Addiction Recovery Consultants

Addiction Recovery Consultants, situated in Berlin, NJ, provides a variety of scientifically-supported treatment options for those struggling with substance use issues and related mental health challenges. This center offers intensive outpatient services, long-term residential stays, and regular outpatient care, accommodating both adults and young adults of all genders. With a focus on methods such as 12-step facilitation, anger management, and brief intervention strategies, the center also extends its services to individuals dealing with trauma or sexual abuse histories. Clients can anticipate personalized care designed to meet their specific needs, fostering an encouraging atmosphere for healing and recovery.

Addiction Recovery Services

Situated in Cleveland, Ohio, Addiction Recovery Services provides a wide range of addiction treatment options, including detoxification and services for substance use disorders. The center features intensive outpatient programs, standard outpatient care, and partial hospitalization or day treatment programs. Emphasizing 12-step facilitation, brief interventions, and cognitive behavioral therapy, this facility serves a diverse clientele, including adults, seniors, and young adults across all genders. Additionally, specialized programs are designed for those dealing with both pain and substance use issues. Addiction Recovery Services is committed to delivering high-quality care to aid individuals in their recovery process.

Addiction Therapeutic Services

Nestled in Rancho Mirage, CA, Addiction Therapeutic Services is dedicated to providing a full spectrum of care for those facing addiction and accompanying mental health challenges. They offer essential detox services and personalized care strategies for adults managing severe mental health conditions, as well as children experiencing significant emotional distress. Their treatment offerings include robust intensive outpatient and day treatment options, ensuring a flexible approach to recovery. Employing methods like 12-step guidance and anger management techniques, their programs aim to foster enduring sobriety. Specialized support is available for active military personnel, teenagers, and adult men. Catering to individuals of all ages and genders, this center is committed to delivering exceptional care within a nurturing setting.

Addiction Treatment of Maryland

Addiction Treatment of Maryland in Dundalk, MD, delivers a complete suite of substance abuse recovery programs designed for adults and adolescents. Their offerings include intensive outpatient, standard outpatient, and day treatment, emphasizing 12-step support, emotional regulation, and rapid intervention strategies. Distinctive services are available for adult men, adult women, and survivors of domestic or intimate partner abuse. The center also provides transitional living accommodations, halfway house placements, and sober living environments. By offering distinct care pathways for male and female patients, this facility is committed to delivering effective treatment to guide individuals toward lasting sobriety.

Addiction Treatment Services

Addiction Treatment Services, situated in Traverse City, MI, provides an extensive range of services for individuals grappling with substance use disorders and mental health challenges. This center offers various treatment modalities, including intensive outpatient, outpatient, and day programs, incorporating methods like 12-step support, anger management, and short-term therapeutic strategies. Tailored programs are available for adolescents and both adult men and women, ensuring a broad spectrum of support for different demographics. Emphasizing personalized care, the center fosters a nurturing atmosphere for those pursuing healing from addiction and mental health difficulties.

Addiction Treatment Services

Situated in Traverse City, MI, Addiction Treatment Services is dedicated to providing focused care for adult males struggling with substance abuse issues. The center offers a variety of treatment options, including both long-term and short-term residential programs, as well as around-the-clock care customized to meet each person's specific requirements. Emphasizing techniques like 12-step facilitation, anger management, and brief intervention strategies, this facility is equipped to support individuals facing concurrent serious mental health challenges. Additionally, it provides specialized programs for those impacted by intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, seniors, and young adults, the center's male-focused methodology fosters a nurturing atmosphere for clients pursuing thorough and empathetic addiction treatment.

Addiction Treatment Services

Traverse City's premier rehabilitation center offers complete assistance for those battling substance abuse and co-occurring psychological challenges. This facility delivers inpatient hospital detox and treatment designed for adults and young adults. Employing strategies such as 12-step facilitation, brief intervention, and community reinforcement with vouchers, the center customizes its methods to address each patient's specific requirements. Specialized services cater to adult men and women, as well as those affected by intimate partner violence. Dedicated to superior care and personalized recovery plans, the center strives to empower clients toward sustained healing.

Addiction Treatment Services

Addiction Treatment Services in Traverse City, MI, provides a complete spectrum of tailored programs for individuals facing substance use challenges. The center offers extended stay, short-term residential, and intermediate housing for adult women on their recovery journey. Employing methods like 12-step guidance, emotional regulation training, and quick intervention strategies, the center promotes a thorough treatment experience. Distinct programs are designed for adults with combined substance use and severe mental health conditions, as well as for children with emotional difficulties. Specialized support is extended to clients who have endured intimate partner abuse. Catering to adults, older adults, and young adults, this establishment is dedicated to delivering excellent care and personalized rehabilitation plans for its female clientele in a nurturing setting.

Addiction Trt Servs International

Addiction Trt Servs International, located in Absecon, NJ, provides thorough and customized care for individuals facing addiction. The center focuses on addressing substance use disorders in adults and concurrent mental health or emotional challenges in children. Their therapeutic offerings include intensive outpatient and day treatment, incorporating elements like 12-step facilitation, anger management techniques, and brief intervention strategies. Addiction Trt Servs International designs specialized programs for adult men and women, as well as young adults, ensuring each person receives attention suited to their specific needs. The center is recognized for its gender-specific treatment approaches and dedication to fostering overall well-being and recovery. They employ proven methods to guide individuals toward lasting healing.

Addictions Crisis Center
Clifton Springs, NY

Situated in Clifton Springs, NY, the Addictions Crisis Center delivers extensive detox services aimed at both adults and young adults facing addiction challenges. Emphasizing 12-step support, anger management, and short intervention strategies, this facility offers tailored programs for adult males, adult females, and individuals with a history of trauma. Providing around-the-clock residential care and detoxification, the center serves clients of all genders. Renowned for its high standards of care and personalized treatment plans, the Addictions Crisis Center stands out as an excellent option for individuals pursuing efficient and customized recovery from addiction.

Addiction Services and Pharmacotherapy

Addiction Services and Pharmacotherapy in Kenosha, WI, provides outpatient substance abuse treatment including detoxification and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Their expertise lies in brief interventions, cognitive behavioral therapy, and motivational interviewing to confront addiction challenges. This center is dedicated to offering tailored support for adults and young adults across all genders, ensuring a high standard of care and assistance for individuals on their journey to recovery. Reach out to them for customized, successful treatment strategies aimed at long-term healing.

Addiction Treatment Center of NE

Situated in Brighton, MA, the Addiction Treatment Center of NE provides extensive outpatient services aimed at addressing substance use issues and co-occurring mental health conditions for both adults and children. The center features tailored care through outpatient treatments that include methadone/buprenorphine or naltrexone, facilitation of 12-step programs, anger management sessions, and brief therapeutic interventions. It also offers specialized programs for adult men and women, as well as those with experiences of intimate partner or domestic violence. Catering to individuals of all genders, this center emphasizes personalized treatment plans and evidence-based methodologies to foster enduring recovery and enhance overall wellness.

Addiction Recovery Systems
Cape May Court House, NJ

Addiction Recovery Systems, situated in Cape May Court House, NJ, provides a wide array of treatment options for substance use disorders. The center features intensive outpatient programs, standard outpatient services, and medication-assisted treatments with methadone, buprenorphine, or naltrexone. It focuses on methods such as anger management, brief interventions, and cognitive behavioral therapy. Catering to a varied population that includes adult males, adult females, and clients involved with the criminal justice system, Addiction Recovery Systems is dedicated to delivering tailored care for adults and young adults of all genders, aiming to support effective recovery from addiction.

Addiction/Behavioral Csl Servs

Addiction/Behavioral Csl Servs, situated in Merrillville, IN, delivers all-encompassing care for individuals of all ages struggling with substance abuse. Their program offerings include intensive outpatient, outpatient, and standard outpatient services. The center employs proven therapeutic methods such as 12-step facilitation, anger management, and brief intervention, serving both male and female clients. They also feature tailored programs for active military members, adult men, and adult women, demonstrating a dedication to individualized support. Addiction/Behavioral Csl Servs is committed to providing high-quality recovery assistance.

Addiction Services and Pharmacotherapy

Addiction Services and Pharmacotherapy, situated in Madison, WI, provides an extensive range of outpatient services aimed at tackling addiction. This center is dedicated to detoxification and treatment for substance use disorders, employing methods like motivational interviewing, relapse prevention strategies, and personalized counseling. It offers specialized programs for active-duty military personnel, as well as for adult men and women. Targeting both adult and young adult populations, the center delivers outpatient detoxification services alongside medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Committed to quality care, Addiction Services and Pharmacotherapy caters to both male and female clients in pursuit of recovery from addiction.

Addiction Treatment Strategies

At Addiction Treatment Strategies in Edwardsville, IL, we provide extensive support for adults and children grappling with substance use disorders and co-occurring mental health challenges. Our offerings include intensive outpatient programs, outpatient detoxification, and general outpatient care, all grounded in proven methods like cognitive behavioral therapy and contingency management. We are dedicated to a personalized approach, creating custom treatment plans for adults and seniors across all genders. Addiction Treatment Strategies is distinguished by its commitment to exceptional, individualized care, guiding each person toward lasting recovery.

Addiction Recovery Medical Services

Addiction Recovery Medical Services in Taylorsville, NC, provides comprehensive outpatient services, including substance use disorder treatment and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. The facility emphasizes therapeutic interventions such as 12-step program integration, motivational interviewing, and cognitive behavioral therapy. Catering to adult men and women, including those affected by domestic or intimate partner violence, they offer personalized care for adult and young adult clients of all genders. Their commitment to a supportive, evidence-informed approach ensures high-quality treatment aimed at fostering lasting recovery.

Addiction Research and Treatment Inc

Addiction Research and Treatment Inc, situated in Antioch, CA, delivers targeted programs for adults and young adults overcoming substance use disorders. Their offerings include outpatient care, featuring medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center emphasizes 12-step integration, individual counseling for addiction, and remote therapy options. Specialized support is provided for active military members, adult men, and adult women, catering to diverse client populations. Addiction Research and Treatment Inc ensures comprehensive and personalized care to aid clients in their recovery journey.

Addiction Research and Treatment Inc

Addiction Research and Treatment Inc, situated in Porterville, CA, provides extensive outpatient support for those pursuing freedom from addiction. The facility excels in offering detoxification, substance abuse therapy, and care for dual-diagnosis mental health issues, catering to both adults and younger individuals. Through approaches like cognitive behavioral therapy, motivational interviewing, and strategies for avoiding relapse, they craft personalized care paths aimed at sustained sobriety. Specialized offerings exist for active military members, adult men, and women. Addressing adults and young adults across all gender identities, this center delivers exceptional care and encouragement to those embarking on their healing path.

Addiction Recovery Medical Services

Addiction Recovery Medical Services located in Statesville, NC, delivers extensive addiction treatment tailored for both adults and young adults. This facility offers detox services along with substance abuse programs, including intensive outpatient, outpatient, and outpatient detox options. Emphasizing a variety of therapeutic methodologies such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, the center customizes its approaches to meet the unique requirements of each individual. Specialized programs are available for adult men, adult women, and individuals who have faced intimate partner or domestic violence. With a commitment to gender-specific care, the center fosters a nurturing atmosphere conducive to recovery. If you're seeking effective addiction treatment within a supportive environment, Addiction Recovery Medical Services is an excellent choice.

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The Addictions Care Center of Albany Inc, located in Albany, NY, provides extensive addiction treatment options, including intensive outpatient, outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their specialized services encompass anger management, brief intervention strategies, and cognitive behavioral therapy. The center features distinct programs designed for adult men, women, and survivors of intimate partner or domestic violence. Catering to adults and young adults across genders, they ensure individualized care plans. The Addictions Care Center of Albany Inc is dedicated to delivering high-quality treatment and compassionate support, aiming to foster the recovery and overall health of every person who seeks their assistance.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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