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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Community Guidance Center

Situated in Clearfield, PA, the Community Guidance Center presents effective rehabilitation options for adults and older individuals facing challenges related to substance use and concurrent mental health disorders. Emphasizing outpatient and intensive outpatient care, this center offers dedicated programs for active duty service members, teenagers, and adult males. The facility employs various therapeutic methods, including anger management, cognitive behavioral techniques, and motivational interviewing, serving both male and female populations. For those looking to address substance use or mental health concerns, the Community Guidance Center delivers holistic support that is customized to meet each person’s unique requirements, fostering an environment for healing and recovery.

Community Health Connections Inc

Situated in Fitchburg, MA, Community Health Connections Inc delivers extensive outpatient services for individuals facing substance use challenges, including adults and children grappling with significant mental health conditions. The center features tailored programs aimed at individuals dealing with HIV/AIDS, as well as those with dual diagnoses involving mental and substance use disorders, along with pain management issues related to substance use. Emphasizing cognitive behavioral therapy and community reinforcement techniques, this facility also provides outpatient options for methadone, buprenorphine, or naltrexone treatments. Catering to adults and seniors of all genders, it prioritizes personalized care and support for those pursuing recovery from addiction and mental health difficulties.

Community Health Connections Inc

Community Health Connections Inc, located in Fitchburg, MA, provides extensive outpatient treatment for substance use issues in adults and children grappling with concurrent mental health disorders. Their specialized services are designed for those facing both addiction and significant emotional challenges. Offerings include outpatient treatment with methadone/buprenorphine as well as cognitive behavioral therapy. The center employs evidence-based strategies like brief interventions and community reinforcement with vouchers. They focus on customized care for individuals dealing with both chronic pain and substance use issues, accommodating adults and seniors of all genders. Community Health Connections Inc is committed to offering exceptional, personalized rehabilitation services aimed at fostering recovery and overall wellness.

Community Health Connections Inc

Community Health Connections Inc in Leominster, MA, provides expert outpatient services for individuals of all ages struggling with substance use and related mental health challenges. Their personalized treatment plans incorporate proven methods like cognitive behavioral therapy and community reinforcement. They also offer distinct programs designed for those managing co-occurring mental health and addiction issues, as well as individuals facing the complexities of pain and substance dependence. Welcoming adults and seniors without regard to gender, this center distinguishes itself with a broad spectrum of recovery options, including outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. Community Health Connections Inc is dedicated to delivering high-quality, personalized support, making it a reliable choice for anyone on their journey to recovery.

Community Health Resources

Community Health Resources in Willimantic, CT, provides extensive recovery programs focused on addiction and dual diagnoses. This facility offers extended stay in a nurturing setting. Utilizing methods such as dialectical behavior therapy, motivational interviewing, and relapse prevention strategies, this establishment supports adult men navigating past experiences and concurrent conditions. Geared towards men of all ages, including older adults and younger individuals, the program is tailored to address the specific requirements of its male clientele. Community Health Resources guarantees excellent support for individuals pursuing freedom from dependency and psychological struggles.

Community Health Resources

Community Health Resources, situated in Manchester, CT, delivers extensive treatment options for substance use issues alongside targeted support for those experiencing both substance use disorders and significant mental health challenges. It features intensive outpatient and outpatient services, offering treatments such as methadone/buprenorphine and naltrexone. The center emphasizes therapies like anger management, brief intervention, and cognitive behavioral therapy, serving adults, seniors, and providing specific programs for adolescents, men, and women. By implementing a personalized and gender-sensitive approach, this facility guarantees exceptional care for anyone on their journey to recovery and improved mental health.

Community Guidance Center
Northern Cambria, PA

Serving Northern Cambria, PA, the Community Guidance Center delivers extensive substance abuse care and targeted support for adults with severe mental health conditions and children facing significant emotional challenges. The center offers various treatment approaches, such as intensive outpatient programs, standard outpatient services, and partial hospitalization. Emphasizing techniques like anger management, cognitive behavioral therapy, and motivational interviewing, they support a diverse clientele including adults, seniors, adolescents, active military, adult males, and provide gender-specific tracks for men and women. The Community Guidance Center is committed to providing excellent recovery services tailored to each person's specific requirements.

Community Health Connections Inc

Community Health Connections Inc. in Gardner, MA, delivers outpatient services for adults and children grappling with substance use and co-occurring mental health challenges. Their tailored programs address individuals experiencing mental illness, emotional difficulties, pain, and addiction. Employing proven methods such as cognitive behavioral therapy and community reinforcement, they offer comprehensive care to men and women of all ages, including seniors. This center prioritizes brief interventions and individualized recovery strategies to guide patients toward lasting wellness.

Community Guidance Center

At our Du Bois, PA facility, the Community Guidance Center is dedicated to providing expert care for adults and older adults facing challenges with substance abuse and accompanying mental health concerns. We offer a range of treatment levels, including intensive outpatient, day treatment, and partial hospitalization. Our therapeutic methods are grounded in proven techniques like cognitive behavioral therapy and motivational interviewing. We feature distinct programs designed for active military personnel, young people, and adult men. Our services also address anger management and deliver personalized support for both men and women, ensuring a holistic approach to recovery and well-being.

Community Health Centers of SE IA

Situated in West Burlington, IA, Community Health Centers of SE IA delivers an extensive array of substance abuse treatment options for both adults and children facing concurrent mental health challenges. The facility offers a variety of treatment modalities, including intensive outpatient services, outpatient care, and medications such as methadone, buprenorphine, and naltrexone. Emphasizing 12-step support, anger management strategies, and brief therapeutic interventions, the center customizes its programs for each individual, promoting a tailored recovery experience. Dedicated to serving all genders among adults and seniors, this center is noted for its pledge to providing exceptional care and personalized treatment strategies.

Community Health Centers of SE IA

Community Health Centers of SE IA, situated in West Burlington, IA, specializes in outpatient substance use disorder services for adults grappling with co-occurring severe mental health conditions. They also provide support for children experiencing emotional disturbances. The facility offers medication-assisted treatment options including methadone, buprenorphine, and naltrexone, alongside general outpatient rehabilitation. Their therapeutic interventions emphasize 12-step program integration, brief counseling techniques, and cognitive behavioral therapy, all customized to meet the unique needs of each client. This center is dedicated to delivering effective addiction treatment to both men and women.

Community Health Network
Indianapolis, IN

Situated in Indianapolis, IN, Community Health Network specializes in outpatient care for adults grappling with substance abuse and concurrent severe mental health conditions, along with emotional issues in children. The center employs a variety of treatment strategies such as 12-step programs, anger management, and brief therapy sessions. It offers customized programs for adolescents, as well as adult men and women, addressing a wide spectrum of needs. Catering to individuals of all ages and genders, Community Health Network provides effective care through outpatient services including methadone/buprenorphine or naltrexone treatment. For those in search of thorough and personalized addiction rehabilitation, this facility stands out as a leading option in the Indianapolis area.

Community Health Resources

Situated in Danielson, CT, Community Health Resources delivers extensive treatment solutions for individuals facing substance use challenges, including both adults and young adults. The center specializes in addressing co-occurring substance use disorders and serious mental health conditions in adults, along with emotional issues in children. It offers both intensive outpatient and outpatient programs. Treatment methodologies include anger management, brief intervention, and cognitive behavioral therapy, accommodating both male and female clients, including survivors of sexual abuse. With an emphasis on personalized care and high-quality support, Community Health Resources stands out as a reliable option for effective rehabilitation services.

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Community For New Direction in Columbus, OH, provides a full spectrum of addiction recovery support. This includes accommodations in transitional living and halfway house settings. The center focuses on aiding adults with dual diagnoses of substance abuse and significant mental health conditions, as well as children facing severe emotional challenges. Through intensive outpatient and standard outpatient programs, they employ methods like 12-step encouragement, strategies for managing anger, and short-term counseling. Specialized programs are offered for adult men and women, individuals affected by domestic violence or intimate partner abuse, and survivors of such experiences. The facility extends its services to both male and female adults and young adults, ensuring personalized care that addresses each person's unique situation.

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Community Health Associates, situated in Yuma, AZ, provides extensive support for recovery. They focus on assisting adults and youth with issues related to substance abuse and accompanying mental health challenges. Their services include intensive and standard outpatient care, incorporating medication-assisted treatment options like methadone and buprenorphine. The center employs proven therapeutic methods, including 12-step support, techniques for managing anger, and brief counseling strategies. Community Health Associates offers tailored programs for teenagers, adult males, and adult females, serving a diverse age range from adolescents to seniors. Their commitment lies in delivering high-quality, personalized care to guide each person toward lasting wellness.

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Community Health Associates, located in Yuma, AZ, provides an extensive array of substance abuse treatment options designed for both adults and children facing significant mental health challenges. Their offerings include intensive outpatient and standard outpatient programs, utilizing therapies such as methadone/buprenorphine and naltrexone. The center focuses on a variety of therapeutic methods, such as 12-step facilitation, anger management, and brief interventions. Additionally, they have specialized programs aimed at adolescents as well as adult men and women, ensuring that care is appropriately tailored to different groups. Catering to adults and seniors of all genders, Community Health Associates is dedicated to delivering high-quality support and assistance for individuals on their journey to recovery from substance use and related mental health issues.

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Community Health Associates, situated in Yuma, AZ, specializes in rehabilitation services tailored for adults and seniors facing challenges related to substance use disorders and concurrent serious mental health conditions. The center offers a range of treatment options, including intensive outpatient programs, outpatient services, and medication-assisted therapies with methadone, buprenorphine, or naltrexone. Emphasizing a 12-step approach, along with anger management and brief intervention strategies, this facility serves adult men, adult women, and adolescents. Gender-specific programs are designed to provide customized care. Community Health Associates is known for its all-encompassing and empathetic treatment approach, making it an excellent option for individuals seeking effective and personalized support in their journey towards addiction recovery.

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Situated in San Luis, AZ, Community Health Associates delivers extensive treatment for adults facing substance use issues alongside serious mental health disorders, as well as support for emotionally troubled children. The center features both intensive outpatient and standard outpatient programs, offering treatments that include methadone/buprenorphine and naltrexone. With targeted programs designed for adolescents, as well as adult men and women, it addresses a broad spectrum of client needs. By employing methods such as 12-step facilitation, anger management, and brief interventions, Community Health Associates guarantees personalized support. Catering to adults and seniors of all genders, this center emphasizes high-quality care and assistance for individuals on their journey to recovery from addiction and mental health difficulties.

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Community Health Associates, located in Douglas, AZ, provides targeted substance abuse recovery programs for adults facing co-occurring serious mental health conditions, as well as for children with emotional disturbances. They offer intensive and standard outpatient services, including medication-assisted treatment with methadone or buprenorphine. The center employs strategies like 12-step facilitation, anger management training, and brief intervention techniques. Specialized programming is offered for adolescents, adult men, and women. Catering to adults and seniors of all genders, the facility focuses on delivering complete care through individualized treatment strategies. Community Health Associates is committed to offering superior rehabilitation support to aid individuals in their path toward wellness.

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Community Health Associates in Parker, AZ, delivers tailored recovery support for adults and older individuals facing addiction and co-occurring mental health challenges. They offer structured outpatient programs, including intensive options and medication-assisted treatment using methadone, buprenorphine, or naltrexone. The center emphasizes evidence-based approaches like 12-step integration, anger regulation, and brief counseling strategies. Their services are designed for adult men, women, and teens, providing dedicated and impactful rehabilitation to all clients.

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Community Health Centers of SE IA, situated in Keokuk, IA, delivers a variety of expert rehabilitation programs. This facility offers robust intensive outpatient options, general outpatient services, and specialized medication-assisted treatment (methadone/buprenorphine or naltrexone) for individuals battling substance use disorders and related mental health challenges. Designed for adults and seniors across all demographics, the center emphasizes personalized treatment plans. Employing methods like 12-step facilitation, anger management techniques, and brief intervention strategies, they ensure a thorough rehabilitation process. For those looking for customized recovery paths within a nurturing setting, this establishment is committed to offering excellent support throughout your healing process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)