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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Community Medical Services

Community Medical Services, situated in Kingman, AZ, delivers a wide range of substance use rehabilitation options. These include outpatient programs utilizing methadone, buprenorphine, and naltrexone, in addition to general outpatient services and diverse therapeutic methods such as cognitive behavioral therapy and anger management. The center serves adult men and women, pregnant and postpartum individuals, as well as young adults. Emphasizing personalized treatment, the facility offers programs designed specifically for different genders and age groups. Clients are assured of receiving high-quality, evidence-based care within a nurturing setting. For anyone looking to overcome addiction—either for themselves or a family member—Community Medical Services is committed to supporting the journey towards sustainable recovery.

Community Medical Services

Situated in Aurora, CO, Community Medical Services provides outpatient detoxification and programs for treating substance use disorders in adults and young adults. The center focuses on personalized care for both male and female clients. By employing cognitive behavioral therapy, motivational interviewing, and contingency management, this facility offers a holistic approach to addiction recovery. With available outpatient treatments, including methadone/buprenorphine and naltrexone, the center fosters a nurturing atmosphere for individuals seeking assistance. Community Medical Services emphasizes high-quality care and tailored treatment strategies, positioning it as a premier option for those aiming to conquer substance use challenges.

Community Medical Services

Situated in Phoenix, AZ, Community Medical Services provides outpatient treatment for substance use, focusing on methadone/buprenorphine and naltrexone options. The center emphasizes personalized treatment, utilizing brief interventions, cognitive behavioral therapy, and motivational incentives. Specifically catering to pregnant and postpartum women, the facility serves adults and young adults of all genders. Community Medical Services is committed to delivering high-quality care and support for individuals pursuing addiction recovery, positioning itself as an essential resource for those starting their healing journey.

Community Medical Services

Situated in Casa Grande, AZ, Community Medical Services provides extensive outpatient programs for treating substance use disorders. The center focuses on outpatient treatments involving methadone, buprenorphine, or naltrexone, incorporating proven methods like brief interventions, cognitive behavioral therapy, and motivational incentives. The facility serves adults and young adults of diverse backgrounds, with dedicated programs for pregnant or postpartum women. Emphasizing personalized care and tailored treatment strategies, Community Medical Services strives to create a nurturing atmosphere for those on their journey to recovery from substance use issues.

Community Medical Services

Community Medical Services, situated in Milwaukee, WI, specializes in outpatient treatment for substance use in both adults and young adults who are also dealing with significant mental health issues. The center employs a variety of targeted therapeutic methods such as cognitive behavioral therapy, motivational interviewing, and contingency management. Programs are specifically designed to meet the needs of active duty military personnel and both male and female clients. With an emphasis on outpatient options including methadone, buprenorphine, or naltrexone therapies, the facility provides thorough support for those on their path to recovery. The center is committed to delivering high-quality, evidence-driven care to foster sustainable healing and sobriety.

Community Medical Services

Situated in Nogales, AZ, Community Medical Services provides a wide array of substance use treatment options, including outpatient services, and programs involving methadone, buprenorphine, or naltrexone. The center focuses on anger management, brief interventions, and cognitive behavioral therapy. Community Medical Services offers customized programs specifically designed for adult men, women, and those who are pregnant or in the postpartum stage, accommodating a varied clientele. This facility extends its services to adults and young adults of all genders, ensuring a supportive and professional atmosphere for individuals looking for effective addiction treatment.

Community Medical Services

Situated in Peoria, AZ, Community Medical Services delivers outpatient treatment for substance use, emphasizing high-quality care and methods grounded in evidence. The center offers treatment options with methadone, buprenorphine, or naltrexone on an outpatient basis, integrating brief interventions, cognitive behavioral therapy, and motivational incentives through contingency management. Community Medical Services focuses on the needs of pregnant and postpartum women while catering to adults and young adults of all genders. Dedicated to personalized care, this center fosters a nurturing atmosphere for individuals striving to conquer addiction.

Community Medical Services

Community Medical Services, situated in Columbus, OH, delivers targeted substance abuse recovery services for adults and young adults. The center offers comprehensive outpatient care, including intensive programs and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic strategies like brief intervention, cognitive behavioral therapy, and community reinforcement with voucher incentives, they prioritize effective treatment. Community Medical Services supports adult men and women, including those with a history of trauma. Their gender-informed recovery tracks offer individualized assistance to both men and women pursuing sobriety from addiction.

Community Medical Services

Community Medical Services in Phoenix, AZ, delivers thorough addiction recovery support for adults and young adults. Their services include intensive outpatient programs, standard outpatient care, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods such as cognitive behavioral therapy and contingency management, the center creates individualized recovery strategies. Dedicated support is available for expectant and new mothers. Community Medical Services is committed to providing high-quality, empathetic care to all clients, male and female, who are pursuing lasting sobriety. For those in Phoenix seeking tailored, scientifically-backed treatment, Community Medical Services is a dedicated partner in the recovery process.

Community Medical Services

Community Medical Services in Lima, OH, provides extensive addiction treatment solutions. Their programs include intensive outpatient, outpatient, and medication-assisted options such as methadone, buprenorphine, or naltrexone. They employ proven therapeutic methods like brief intervention, cognitive behavioral therapy, and community reinforcement with incentives. The center also offers specialized support for adult men, adult women, and individuals with trauma histories. Open to adults and young adults across all gender identities, they deliver high-quality, supportive care. For those pursuing successful recovery from substance use disorders, Community Medical Services is committed to guiding individuals toward sustained healing.

Community Medical Services

Community Medical Services in Buckeye, AZ, is an outpatient treatment center dedicated to assisting individuals with substance use disorders. They specialize in medication-assisted treatment using methadone, buprenorphine, or naltrexone. The program employs proven therapeutic approaches, including cognitive behavioral therapy, contingency management, and motivational interviewing. A notable area of expertise is their support for pregnant and postpartum women, serving adults and young adults regardless of gender. Community Medical Services emphasizes personalized care, developing treatment plans to meet the unique needs of everyone pursuing recovery. This center offers a supportive setting for those seeking effective, specialized addiction treatment.

Community Medical Services

Community Medical Services, situated in Sierra Vista, AZ, is a dedicated rehabilitation facility providing outpatient care for substance use disorders. The center offers medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Serving adult men, adult women, and pregnant or postpartum women, as well as young adults, Community Medical Services emphasizes tailored recovery journeys for all individuals, with specialized gender-specific programs available for both men and women, ensuring personalized and effective support for addiction recovery.

Community Medical Services

Community Medical Services in Tucson, AZ, provides accessible outpatient addiction treatment options designed to address the unique requirements of its local population. This clinic delivers targeted assistance through services like anger management, cognitive behavioral therapy, and brief interventions. Catering to adult men, adult women, expectant and new mothers, and young adults, the center offers complete support for individuals navigating different life circumstances. Clients can access personalized outpatient care utilizing methadone, buprenorphine, or naltrexone. Prioritizing effective care and customized recovery plans, this facility creates a welcoming setting for both male and female patients pursuing sobriety.

Community Medical Services

Situated in Glendale, AZ, Community Medical Services provides outpatient treatment for substance use disorders, featuring options such as methadone/buprenorphine and naltrexone therapies. This center emphasizes brief interventions, cognitive behavioral therapy, and motivational incentives coupled with contingency management. Catering specifically to pregnant and postpartum women, the facility also serves adults and young adults from all gender identities. Community Medical Services is committed to delivering thorough, evidence-based support to assist individuals in their recovery journey. If you are looking for focused addiction care in a compassionate and nurturing setting, this center aims to offer exceptional services customized to fit your individual circumstances.

Community Medical Services

Community Medical Services in Cedar Park, TX, provides outpatient services for substance use disorders. Their specialties include methadone, buprenorphine, and naltrexone treatment, along with interventions like brief counseling, cognitive-behavioral therapy, and motivational strategies. The center serves adults and young adults of any gender, offering tailored support for individuals with trauma histories, expectant and new mothers, and those involved with the justice system. Community Medical Services is committed to delivering high-quality, personalized care to aid clients in their recovery process.

Community Medical Services

Community Medical Services in Mesa, AZ, delivers outpatient care for adults and young adults struggling with substance use. Their approach utilizes proven methods such as cognitive behavioral therapy and contingency management, incorporating treatments like methadone, buprenorphine, or naltrexone. Prioritizing high-quality care, the center also extends specialized services to expectant and new mothers. All individuals, irrespective of gender, benefit from brief interventions and motivational support to aid their recovery path. Community Medical Services is committed to offering complete and caring addiction treatment solutions to promote enduring sobriety.

Community Medical Services

Situated in Wasilla, AK, Community Medical Services provides outpatient treatment for substance use disorders, featuring options like outpatient methadone/buprenorphine and naltrexone therapy. This center specifically addresses the needs of pregnant and postpartum women while serving adults and young adults of any gender. By employing evidence-based practices including cognitive behavioral therapy, motivational interviewing, and contingency management with motivational incentives, the facility aims to deliver tailored and holistic care for every client. Committed to excellence and empathy, Community Medical Services strives to assist individuals as they work towards recovery from substance use issues.

Community Medical Services

Situated in Kalispell, MT, Community Medical Services specializes in outpatient detoxification and treatment for substance use disorders among adults and young adults. This center offers outpatient services for methadone, buprenorphine, or naltrexone therapy, employing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and contingency management. Aiming for personalized treatment, the facility includes dedicated programs for pregnant or postpartum women. Community Medical Services serves both men and women, promoting a holistic and inclusive strategy for addiction recovery. Those seeking effective rehabilitation services within a nurturing environment can rely on this center for high-quality, empathetic care.

Community Medical Services

Situated in McKinney, TX, Community Medical Services provides comprehensive outpatient substance use recovery programs for adults and adolescents. Their expertise lies in methadone, buprenorphine, and naltrexone treatment, employing evidence-based methods like brief intervention, cognitive behavioral therapy, and motivational interviewing. Community Medical Services supports pregnant and postpartum women, individuals with trauma histories, and those involved with the criminal justice system. Dedicated to superior treatment, this center offers individualized care for all clients, fostering a complete and personalized path to sobriety.

Community Medical Services
Prescott Valley, AZ

Community Medical Services located in Prescott Valley, AZ, provides outpatient treatment for substance use, focusing on programs that utilize methadone, buprenorphine, or naltrexone. This center employs a variety of evidence-based techniques, including cognitive behavioral therapy, motivational interviewing, and contingency management, to facilitate recovery. Aiming for personalized care, the facility serves adults and young adults of all genders. The commitment to delivering high-quality care within a nurturing environment makes this center an excellent option for individuals in need of effective addiction support. Whether clients are looking for outpatient services or specific methadone programs, this facility provides comprehensive assistance to promote enduring recovery.

Community Medical Services

Situated in Anchorage, Alaska, Community Medical Services provides accessible outpatient care for individuals battling substance use disorders. Their services encompass medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center excels in employing evidence-based therapies such as cognitive behavioral therapy, contingency management, and motivational interviewing to foster lasting change. Dedicated to delivering high-quality care, Community Medical Services offers tailored programs specifically for pregnant and postpartum women, serving adults and young adults across all gender identities. Their holistic approach and unwavering dedication to guiding clients toward sustained sobriety are hallmarks of their recovery support.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)