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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Community Health Connections Inc

Community Health Connections Inc in Leominster, MA, provides expert outpatient services for individuals of all ages struggling with substance use and related mental health challenges. Their personalized treatment plans incorporate proven methods like cognitive behavioral therapy and community reinforcement. They also offer distinct programs designed for those managing co-occurring mental health and addiction issues, as well as individuals facing the complexities of pain and substance dependence. Welcoming adults and seniors without regard to gender, this center distinguishes itself with a broad spectrum of recovery options, including outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. Community Health Connections Inc is dedicated to delivering high-quality, personalized support, making it a reliable choice for anyone on their journey to recovery.

Community Health Resources

Community Health Resources in Willimantic, CT, provides extensive recovery programs focused on addiction and dual diagnoses. This facility offers extended stay in a nurturing setting. Utilizing methods such as dialectical behavior therapy, motivational interviewing, and relapse prevention strategies, this establishment supports adult men navigating past experiences and concurrent conditions. Geared towards men of all ages, including older adults and younger individuals, the program is tailored to address the specific requirements of its male clientele. Community Health Resources guarantees excellent support for individuals pursuing freedom from dependency and psychological struggles.

Community Health Resources

Community Health Resources, situated in Manchester, CT, delivers extensive treatment options for substance use issues alongside targeted support for those experiencing both substance use disorders and significant mental health challenges. It features intensive outpatient and outpatient services, offering treatments such as methadone/buprenorphine and naltrexone. The center emphasizes therapies like anger management, brief intervention, and cognitive behavioral therapy, serving adults, seniors, and providing specific programs for adolescents, men, and women. By implementing a personalized and gender-sensitive approach, this facility guarantees exceptional care for anyone on their journey to recovery and improved mental health.

Community Medical Services
Lake Havasu City, AZ

Community Medical Services located in Lake Havasu City, AZ, provides outpatient treatment options for substance use specifically designed for adults and young adults. This center caters to the unique needs of adult men, adult women, and those who are pregnant or in the postpartum phase. The treatment modalities utilized include anger management, brief intervention strategies, and cognitive behavioral therapy. Additionally, the facility offers outpatient services for methadone/buprenorphine or naltrexone. With a commitment to delivering high-quality care, the center strives to assist individuals in their recovery journey from addiction. Both men and women can access customized programs that address their specific circumstances within a nurturing and professional setting.

Community Medical Services

Community Medical Services, situated in Mesa, AZ, delivers thorough addiction recovery services for adults and emerging adults. Their offerings include intensive outpatient, standard outpatient, and medication-assisted treatment options utilizing methadone, buprenorphine, or naltrexone. Employing strategies such as brief intervention, cognitive behavioral therapy, and contingency management, they personalize care plans. The center also features specialized support for expectant and new mothers. Clients receive dedicated attention suited to their individual situations, with services available for all genders. For those in search of effective and empathetic addiction care, the varied approaches at this esteemed establishment are worth exploring.

Community MHC of Crawford County

Situated in Pittsburg, KS, Community MHC of Crawford County delivers outpatient services for substance use to both adults and young adults. The center specializes in treating co-occurring serious mental health issues alongside substance use disorders in adults, as well as serious emotional disturbances in children. It employs regular outpatient methods, incorporating cognitive behavioral therapy, the Matrix Model, and motivational interviewing techniques. Emphasizing personalized care, the center welcomes male and female clients in search of effective rehabilitation options. If you are in need of a customized treatment plan that meets your specific requirements, this facility is committed to assisting you on your path to recovery.

Community Medical Services

Situated in Austin, TX, Community Medical Services provides comprehensive outpatient treatment for substance use issues, featuring options like methadone, buprenorphine, and naltrexone. The facility is known for its expertise in brief interventions, cognitive behavioral therapy, and incentive-based management techniques. Specialized programs are available for those who have faced trauma, as well as forensic clients and women who are pregnant or in the postpartum phase. Catering to both adults and young adults, the center offers personalized care designed for all genders. Community Medical Services is committed to delivering high-quality, evidence-informed treatment to assist individuals in their recovery journey.

Community Medical Services

Situated in San Antonio, TX, Community Medical Services delivers outpatient treatment for substance use, emphasizing methadone, buprenorphine, and naltrexone therapies. This center is dedicated to helping both adults and young adults, utilizing techniques like brief intervention, cognitive behavioral therapy, and motivational incentives alongside contingency management. It features specialized programs designed for individuals who have faced trauma, those involved with the criminal justice system, and pregnant or postpartum women. Offering targeted services for both men and women, this facility ensures that care is customized to meet the unique needs of each client, making it an empathetic option for individuals pursuing effective recovery solutions.

Community Health Network
Indianapolis, IN

Situated in Indianapolis, IN, Community Health Network specializes in outpatient care for adults grappling with substance abuse and concurrent severe mental health conditions, along with emotional issues in children. The center employs a variety of treatment strategies such as 12-step programs, anger management, and brief therapy sessions. It offers customized programs for adolescents, as well as adult men and women, addressing a wide spectrum of needs. Catering to individuals of all ages and genders, Community Health Network provides effective care through outpatient services including methadone/buprenorphine or naltrexone treatment. For those in search of thorough and personalized addiction rehabilitation, this facility stands out as a leading option in the Indianapolis area.

Community Health Resources

Situated in Danielson, CT, Community Health Resources delivers extensive treatment solutions for individuals facing substance use challenges, including both adults and young adults. The center specializes in addressing co-occurring substance use disorders and serious mental health conditions in adults, along with emotional issues in children. It offers both intensive outpatient and outpatient programs. Treatment methodologies include anger management, brief intervention, and cognitive behavioral therapy, accommodating both male and female clients, including survivors of sexual abuse. With an emphasis on personalized care and high-quality support, Community Health Resources stands out as a reliable option for effective rehabilitation services.

Community Hospital of the Monterey

Situated in Monterey, CA, the Community Hospital of the Monterey delivers all-encompassing treatment for substance abuse aimed at adults and adolescents. This center offers a range of options including intensive outpatient programs, general outpatient services, and medication-assisted treatments like methadone/buprenorphine and naltrexone. Employing scientifically-backed methods such as 12-step support, brief interventions, and motivational techniques, the facility customizes its treatment plans to meet individual requirements. Prioritizing personalized attention, the center serves both men and women who are on the path to overcoming addiction. For those seeking effective rehabilitation services infused with compassion, the Community Hospital of the Monterey is dedicated to aiding you in your recovery journey.

Community Health Resources

Community Health Resources, situated in East Hartford, CT, provides a variety of focused therapeutic interventions for individuals of all ages struggling with addiction and co-occurring psychiatric disorders. The center offers diverse care levels, including intensive outpatient, outpatient, and standard outpatient services, all customized through methods like anger management, brief interventions, and cognitive behavioral therapy. Specialized offerings are available for teenagers, adult males, and adult females, in addition to services for adults and older adults regardless of gender. Community Health Resources distinguishes itself through its all-encompassing treatment strategies and an unwavering commitment to personalized support for healing and overall wellness.

Community Human Services

Community Human Services in Seaside, CA, provides extensive support for adults and young adults facing challenges with addiction and accompanying mental health conditions. Their services include inpatient hospital-based detox and treatment, with specific attention given to individuals who have experienced intimate partner violence, domestic violence, or sexual trauma. Employing strategies like 12-step facilitation, anger management, and cognitive behavioral therapy, the center customizes care plans for each person. Community Human Services is open to all genders, fostering a secure and encouraging space dedicated to recovery and well-being.

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Situated in Putnam, CT, Community Health Resources delivers thorough treatment for substance use issues along with dedicated support for those facing severe mental health challenges concurrently. The center features various programs, including long-term residential care, outpatient services, and medication-assisted treatments. Employing methodologies such as 12-step guidance, anger management sessions, and cognitive behavioral therapy, the facility serves adult women and individuals who have endured trauma or sexual abuse. With an emphasis on tailored care for both adult and young adult populations, Community Health Resources is committed to promoting recovery and enhancing overall wellness.

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Located in Texarkana, TX, Community Healthcore delivers comprehensive treatment for adults and youth struggling with addiction and mental health issues. The center's tailored programs address individuals with co-occurring conditions, offering both intensive outpatient and standard outpatient services. Committed to best practices, they implement evidence-based methodologies including 12-step programs and anger management strategies, ensuring customized support for each client. With an emphasis on serving criminal justice and forensic populations, Community Healthcore is recognized for its commitment to holistic approaches to wellness. Catering to both men and women, the facility prioritizes gender-responsive treatments. If you are seeking effective care within a nurturing atmosphere, Community Healthcore could be the right choice for your recovery process.

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At Community Hospitals of Indiana Inc in Indianapolis, IN, we offer extensive recovery support for both younger and older individuals facing addiction and accompanying mental health challenges. Our hospital-based services include inpatient detoxification and comprehensive treatment programs, with distinct tracks designed for teens, adult men, and adult women. We employ proven therapeutic methods like 12-step encouragement, emotional regulation training, and short-term counseling to foster lasting sobriety and mental wellness. Our commitment is to provide personalized, high-quality care aimed at improving each person's overall health.

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Situated in Monterey, California, Community Human Services specializes in substance use recovery for both adults and young adults. The center offers a variety of treatment options, including intensive outpatient and standard outpatient programs, each customized to meet the unique requirements of its clients. Employing techniques like 12-step support, anger management, and brief interventions, the facility ensures a focus on individualized care. With dedicated programs that highlight personalized treatment strategies, Community Human Services serves both men and women. This center is recognized for its thorough and empathetic approach to addiction treatment, positioning it as a leading option for individuals pursuing high-quality care in the Monterey region.

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Situated in Salinas, CA, Community Human Services delivers outpatient support for individuals grappling with substance use concerns, serving both adults and younger adults. Their regular outpatient services are grounded in proven therapeutic methods, including 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. This facility emphasizes personalized care, accommodating both male and female clients. Community Human Services distinguishes itself through its thorough treatment plans, aimed at empowering individuals toward a path of recovery. For those seeking tailored addiction care provided with skill and empathy, this center is committed to delivering exceptional services to foster enduring sobriety.

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Situated in Keene, NH, Community Improvement Associates specializes in a wide range of substance use recovery programs. This center features intensive outpatient services, standard outpatient care, and medication-assisted therapies with methadone, buprenorphine, or naltrexone. It employs various methodologies, including anger management, brief interventions, and cognitive behavioral therapy, to serve adults, teenagers, and active duty military members. With distinct initiatives for adult males and services for all genders, the center provides personalized care tailored to individual needs. Whether you are pursuing treatment for yourself or someone dear to you, Community Improvement Associates offers dedicated support and high-quality care for those seeking to heal and recover.

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Located in Falls City, NE, Community Medical Center provides outpatient services for individuals facing substance use challenges, including both adults and children who also deal with mental health issues. This center focuses on effective techniques such as brief interventions, cognitive behavioral therapy, and motivational interviewing to tailor treatment plans for various demographics, including adult men and women, young individuals, and seniors, while also offering programs designed for specific gender needs. Emphasizing the use of outpatient treatments like methadone, buprenorphine, or naltrexone, the facility is committed to delivering extensive support to those striving for recovery. Community Medical Center aims to provide superior, evidence-informed care to facilitate enduring sobriety and mental health improvement for its clients.

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The Community Medical Clinic/Behav Health, situated in Oak Grove, LA, provides a full spectrum of outpatient care for chemical dependency and recovery. Their expertise lies in outpatient detox, medication-assisted treatment (including methadone, buprenorphine, or naltrexone), and a strong emphasis on brief interventions, strategies to avoid relapse, and therapeutic counseling for addiction. They have specialized programs designed for active military members, young people, and adult males. This center extends its services to adult and senior individuals of any gender, ensuring personalized treatment plans. The Community Medical Clinic/Behav Health is devoted to guiding individuals toward lasting sobriety through high-quality, research-backed methods.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)