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Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Community Medical Services

Community Medical Services in Fargo, ND, provides outpatient addiction recovery services for adults and young adults. They have a dedicated program for women who are pregnant or have recently given birth. Their treatment options include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, combined with proven therapeutic techniques like cognitive behavioral therapy, motivational interviewing, and contingency management. Community Medical Services is committed to delivering high-quality, comprehensive care for all clients pursuing sobriety. This center offers a supportive setting and effective treatments to guide individuals toward lasting recovery.

Community Medical Services

Community Medical Services in Marion, IN, delivers outpatient substance use disorder treatment designed for adults and young adults. They provide specialized support for pregnant and postpartum women, as well as individuals involved with the criminal justice system. Their treatment methodologies encompass cognitive behavioral therapy, motivational interviewing, and contingency management. Additionally, the center offers outpatient treatment using methadone, buprenorphine, or naltrexone. Community Medical Services is committed to high-quality, gender-inclusive care for all clients navigating substance use challenges.

Community Medical Services

Community Medical Services in Tucson, AZ, provides thorough addiction treatment via outpatient programs. These services encompass medication-assisted treatment, such as methadone, buprenorphine, or naltrexone. The facility also focuses on anger management, brief intervention strategies, and cognitive behavioral therapy. They offer customized programs for adult men, adult women, and pregnant or postpartum women, ensuring individualized support. Serving adults and young adults of all genders, the center fosters a welcoming and inclusive atmosphere. Community Medical Services is committed to delivering high-quality, evidence-based care to support sustained recovery from addiction.

Community Medical Services

Community Medical Services in Tucson, AZ, specializes in outpatient care for adults and young adults struggling with substance use. They offer treatment using methadone, buprenorphine, or naltrexone, incorporating strategies such as anger management, brief intervention, and cognitive behavioral therapy. The center provides tailored programs for adult men, adult women, and pregnant or postpartum women, accommodating a wide range of client needs. Their services are available to both male and female individuals, reflecting a holistic approach to recovery. Community Medical Services is dedicated to delivering high-quality, personalized treatment, positioning them as a leading provider of comprehensive addiction rehabilitation.

Community Medical Services

At this Tucson, AZ location, Community Medical Services delivers extensive support for individuals facing substance use challenges via its outpatient services. The center is equipped to offer tailored recovery plans, including methadone, buprenorphine, or naltrexone treatment, alongside general outpatient care, anger management, brief intervention strategies, and cognitive behavioral therapy. Community Medical Services serves a diverse population encompassing adult men, adult women, women who are pregnant or postpartum, adults in general, and young adults. Prioritizing personalized care and scientifically validated methods, this establishment guarantees effective treatment for all clients, regardless of gender, who are pursuing freedom from addiction.

Community Medical Services

Community Medical Services in Dayton, OH, provides extensive addiction recovery services for individuals of all ages. Their offerings include intensive outpatient care, standard outpatient programs, and targeted medication-assisted treatment using methadone, buprenorphine, or naltrexone. The center utilizes proven therapeutic methods like brief intervention, cognitive behavioral therapy, and community reinforcement with incentives to foster lasting sobriety. Specific tracks are available for adult men, adult women, and those with a history of trauma. Emphasizing personalized recovery plans, this center cultivates a welcoming atmosphere for both male and female patients pursuing effective substance use disorder treatment.

Community Medical Services

Community Medical Services, situated in Safford, AZ, delivers outpatient substance abuse treatment for those on the path to recovery. Their specialized services incorporate anger management, brief intervention, and cognitive behavioral therapy. The center offers distinct programs for adult men, adult women, and pregnant or postpartum women, addressing a wide spectrum of individual requirements. Serving adults and young adults of all genders, Community Medical Services provides thorough assistance for individuals confronting addiction. Their offerings include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services, highlighting their dedication to high-quality and holistic recovery.

Community Medical Services

At Community Medical Services in Cincinnati, OH, individuals struggling with substance use disorders find a wide range of support. Their treatment philosophy encompasses various evidence-based methods, including brief intervention, cognitive behavioral therapy, and the community reinforcement approach with voucher incentives. The center delivers a spectrum of care, from intensive outpatient programs to standard outpatient services, and also offers medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone for adults. This facility is equipped to assist adult men and women, including those with a history of trauma, and welcomes young adults of all gender identities. Community Medical Services prioritizes personalized and high-quality care to guide each client through their recovery journey. They are committed to delivering effective and empathetic addiction treatment for those in need.

Community Medical Services

Community Medical Services in Phoenix, AZ, delivers outpatient care for individuals struggling with substance use. Their approach incorporates evidence-based methods like brief intervention, cognitive behavioral therapy, and motivational incentives, utilizing medications such as methadone, buprenorphine, and naltrexone. The center offers specialized services for pregnant and postpartum women and develops individualized treatment plans for both male and female clients, aiming to guide them toward lasting recovery.

Community Medical Services

Community Medical Services in Fond du Lac, WI delivers extensive outpatient care for individuals struggling with addiction and related mental health challenges, serving both adults and youth. The center features distinct programs tailored for active duty service members, adult men, and adult women. Their therapeutic interventions encompass cognitive behavioral therapy, motivational interviewing, and contingency management. Available medication-assisted treatment includes methadone, buprenorphine, or naltrexone for adults and young adults of all genders. The skilled team at this location is committed to offering superior support and treatment to guide people toward healing.

Community Medical Services

Nestled in Missoula, MT, Community Medical Services provides comprehensive outpatient services for individuals struggling with substance use. Their expertise lies in medication-assisted treatment, utilizing methadone, buprenorphine, and naltrexone for adults and young adults. Employing proven therapeutic strategies such as cognitive behavioral therapy, contingency management, and motivational interviewing, the center is committed to fostering recovery. They offer tailored support for pregnant and postpartum women, serving both men and women. Community Medical Services prioritizes individualized care and effective treatment to guide clients toward sustained sobriety.

Community Medical Services

Community Medical Services in Tempe, AZ, provides complete outpatient care for substance use disorders, utilizing medication-assisted treatments like methadone, buprenorphine, or naltrexone. The facility is particularly equipped to support pregnant and postpartum women, adults, and young adults, offering tailored treatment plans for men and women. Employing methods such as brief interventions, cognitive behavioral therapy, and motivational strategies, they deliver high-quality, research-backed services. Community Medical Services in Tempe is committed to helping individuals and their families achieve lasting recovery and enhanced health in a nurturing setting.

Community Mental Health Center Inc

Situated in Lawrenceburg, IN, Community Mental Health Center Inc specializes in addressing substance use and co-occurring disorders in both adults and children. The center offers a range of therapeutic programs, including intensive outpatient, outpatient, and day treatment options. It employs various methodologies, such as 12-step facilitation, anger management, and brief intervention strategies. Committed to personalized care, the facility serves individuals of all genders, including adults and seniors. Community Mental Health Center Inc is notable for its diverse treatment alternatives and dedication to providing exceptional support for individuals pursuing recovery from addiction and mental health issues.

Community Mental Health Affiliates

Community Mental Health Affiliates, situated in New Britain, CT, offers extensive outpatient care for individuals of all ages struggling with addiction and co-occurring mental health issues. Their specialized services include anger management, brief intervention strategies, and motivational interviewing. The center is equipped to support specific populations such as active duty military personnel, teenagers, and adult men, while also providing gender-tailored treatment for both men and women. They deliver effective care through outpatient, methadone/buprenorphine, and naltrexone-assisted treatment modalities, ensuring personalized support for anyone needing help with substance abuse or significant mental health challenges.

Community Medical Services

Community Medical Services in Grand Forks, ND, specializes in outpatient care for substance use disorders, offering methadone, buprenorphine, and naltrexone therapies. Their treatment framework incorporates scientifically validated methods like cognitive behavioral therapy, contingency management, and motivational interviewing. They have dedicated programs for expectant and new mothers, serving adults and young adults across all gender identities. The center prioritizes personalized recovery plans within a nurturing setting. For those in need of responsive and caring addiction treatment, this center is committed to delivering excellent, individualized services.

Community Mental Health Center Inc

Community Mental Health Center Inc located in Lawrenceburg, IN, provides targeted support for individuals dealing with substance abuse and simultaneous mental health issues for both adults and youth. The center offers a variety of programs, including intensive outpatient and outpatient care, as well as day treatment options. Their approach features 12-step facilitation, anger management strategies, and brief intervention methods. Customized programs are created for adults and seniors across all genders, demonstrating the center's commitment to exceptional care and individualized service. For those seeking reliable, evidence-based treatment in a compassionate setting, this facility's extensive services and focus on personal requirements make it an essential aid for anyone striving for recovery.

Community Mental Health Center Inc

Community Mental Health Center Inc in Vevay, IN provides extensive care for individuals struggling with substance abuse. This facility specializes in treating adults who also experience serious mental health conditions, as well as children with emotional disturbances. Their treatment offerings include outpatient and intensive outpatient services, integrating methodologies like 12-step facilitation, anger management, and brief interventions. Community Mental Health Center Inc is committed to offering personalized care, adapting treatment strategies to the specific needs of adults and seniors across all gender identities. Their dedication to developing customized recovery plans ensures a unique approach for every client. For those looking for scientifically supported treatment within a nurturing setting, this center is devoted to delivering excellent support.

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Situated in Brookville, IN, Community Mental Health Center Inc delivers a wide-ranging substance use rehabilitation program for both adults and children dealing with serious mental health issues alongside addiction. The center features intensive outpatient programs, outpatient day treatment, and partial hospitalization options, employing techniques that include 12-step facilitation, anger management, and brief interventions. Emphasizing personalized care, the facility serves adults and elderly individuals of all genders. Community Mental Health Center Inc is recognized for its customized treatment strategies and dedication to high-quality care, establishing itself as a leading option for individuals in need of effective and individualized rehabilitation solutions.

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Community Mental Health Center Inc, located in Batesville, IN, specializes in delivering thorough treatment for substance use issues and offers targeted support for individuals facing co-occurring disorders related to serious mental health conditions in adults and significant emotional disturbances in children. The facility provides a range of options, including intensive outpatient treatment, general outpatient services, and structured day programs. Utilizing strategies such as 12-step programs, anger management, and focused interventions, the center customizes its services to fit individual circumstances. Committed to an individualized treatment process, adults and seniors of all genders receive exceptional care. This center is recognized for its dedication to meeting the specific needs of each client with understanding and professionalism, making it an excellent choice for personalized rehabilitation solutions.

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Situated in Batesville, IN, Community Mental Health Center Inc delivers focused rehabilitation services tailored for both adults and children dealing with substance use issues and significant mental health challenges. This center offers a range of treatment programs, including intensive outpatient, outpatient, and partial hospitalization, utilizing methods such as 12-step facilitation, anger management, and brief intervention strategies. Emphasizing personalized care, the facility serves adults and seniors of all genders. Community Mental Health Center Inc is distinguished by its wide-ranging treatment offerings and dedication to high-quality care, positioning it as an essential resource for individuals in need of customized rehabilitation support.

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Situated in West Harrison, IN, the Community Mental Health Center Inc delivers a wide range of rehabilitation services aimed at adults and older adults facing challenges related to substance abuse and concurrent mental health disorders. The center provides multiple treatment options, including intensive outpatient programs, day treatment, and partial hospitalization, prioritizing personalized attention. Various therapeutic strategies such as 12-step facilitation, anger management, and brief interventions are employed to meet the specific requirements of each individual. With specialized programs designed for both men and women, this facility creates a nurturing atmosphere for all clients. If you're in search of effective support for addiction and mental health issues, this center is committed to guiding you towards sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)