Buprenorphine Treatment Centers in Mississippi
Medically reviewed by NWVCIL Editorial TeamLast reviewed: May 2026
Our directory lists 48 buprenorphine providers across Mississippi, with the largest concentrations in Jackson (5), Oxford (3) and Meridian (3).
Mississippi had 702 drug overdose deaths in 2023 — a 25.3-per-100,000 age-adjusted rate — and the state's MAT landscape has a notable structural gap: Mississippi Medicaid does not currently reimburse methadone for opioid use disorder. This means that buprenorphine and naltrexone, which can be prescribed in standard outpatient settings, are the primary medications available to Medicaid members, while methadone access depends on the 4 SAMHSA-certified Opioid Treatment Programs operating statewide. NWVCIL's directory tracks 43 buprenorphine providers in Mississippi, with 5 in Jackson, 3 in Corinth, and 3 in Meridian. The Mississippi Department of Mental Health oversees OTP licensing in addition to SAMHSA certification, and the state has invested in expanding office-based buprenorphine access through community mental-health centers and FQHCs. 55 of the 82 verified facilities in our directory accept Medicaid, and 47 offer telehealth. The relative scarcity of in-person specialists outside Jackson makes telehealth-delivered buprenorphine particularly important for Delta and Pine Belt residents. For a Mississippian starting buprenorphine, common pathways include: an intake at a community mental-health center in one of the state's 14 regions, a Federally Qualified Health Center for sliding-fee or Medicaid patients, a private MAT clinic in Jackson, Tupelo, or the Gulf Coast, or a telehealth visit with a Mississippi-licensed prescriber. Most providers can prescribe Suboxone, Subutex, Zubsolv, or the monthly Sublocade injection. SAMHSA's national helpline (1-800-662-4357), the 988 Suicide and Crisis Lifeline, and the Mississippi Department of Mental Health Helpline (1-877-210-8513) are available 24/7.
Treatment landscape in Mississippi:
- Mississippi recorded 702 drug overdose deaths in 2023 at 25.3 per 100,000 (CDC NCHS).
- 43 buprenorphine providers and 4 methadone Opioid Treatment Programs serve the state; Jackson, Corinth, and Meridian anchor access.
- Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.
- The state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.
Buprenorphine in Mississippi — By the Numbers
25.3
per 100,000 drug overdose mortality (CDC 2023)
702
total overdose deaths in Mississippi (2023)
43
buprenorphine providers in our directory
47 / 82
facilities offering telehealth
55
accept Medicaid for treatment
4
SAMHSA-certified Opioid Treatment Programs
Top cities by buprenorphine provider density
Jackson (5) · Corinth (3) · Meridian (3)
Sources: CDC NCHS Drug Overdose Mortality (2023) · SAMHSA Treatment Locator · NWVCIL directory snapshot, May 2026
Mississippi Medicaid
Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.
State regulations
Mississippi has a limited OTP network; the state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.
- Cash or self-payment42
- Federal, or any government funding for substance use treatment programs32
- Private health insurance28
- SAMHSA funding/block grants27
- Medicaid26
- Federal military insurance (e.g., TRICARE)24
- Outpatient32
- Regular outpatient treatment31
- Outpatient methadone/buprenorphine or naltrexone treatment24
- Intensive outpatient treatment20
- Residential/24-hour residential19
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Buprenorphine Treatment Providers in Mississippi
Buprenorphine providers in Mississippi
Jackson · 5 centers

Jackson Comprehensive Treatment Center
Jackson, MS
Services:

Hinds Behavioral Health Services
Jackson, MS
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Jackson VAMC GV Sonny Montgomery
Jackson, MS
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Pathway Healthcare
Jackson, MS
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Corinth · 3 centers

Region IV MHS
Corinth, MS
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Region IV MHS
Corinth, MS
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Region IV MHS
Corinth, MS
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Meridian · 3 centers

HamiltonDavis Treatment Services
Meridian, MS
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Weems Community MH Center
Meridian, MS
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Oxford · 3 centers

Oxford Outpatient Treatment Center
Oxford, MS
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Communicare
Oxford, MS
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Communicare
Oxford, MS
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Biloxi · 2 centers

Mississippi Drug and Alcohol
Biloxi, MS
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Byram · 2 centers

Harbor Houses of Jackson Inc
Byram, MS
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Harbor Houses of Jackson Inc
Byram, MS
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Columbus · 2 centers

Recovery House
Columbus, MS
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Pines and Cady Hill
Columbus, MS
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Hattiesburg · 2 centers

Pine Grove BH and Addiction Servs
Hattiesburg, MS
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PBMHR Region XII
Hattiesburg, MS
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Vicksburg · 2 centers

Belmont Gardens Recovery Center
Vicksburg, MS
Services:
Brandon · 1 center

Defining Wellness Centers
Brandon, MS
Services:
Etta · 1 center

Oxford Treatment Center
Etta, MS
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Greenwood · 1 center

Denton House CDC
Greenwood, MS
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Hernando · 1 center

Region 4 Desoto
Hernando, MS
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Holly Springs · 1 center

Communicare
Holly Springs, MS
Services:
Laurel · 1 center

Pathway Healthcare Laurel
Laurel, MS
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Moselle · 1 center

PBMHR Region XII
Moselle, MS
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Pascagoula · 1 center

Region XIV Singing River Services
Pascagoula, MS
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Pittsboro · 1 center

Communicare
Pittsboro, MS
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Purvis · 1 center

PBMHR Region XII
Purvis, MS
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Ridgeland · 1 center

Innovative Behavioral Services Inc
Ridgeland, MS
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Sardis · 1 center

Communicare
Sardis, MS
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Senatobia · 1 center

Communicare
Senatobia, MS
Services:
Summit · 1 center

PBMHR Region XII
Summit, MS
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Tupelo · 1 center

Region III Chem Dependency
Tupelo, MS
Services:
Tutwiler · 1 center

Life Help/Region 6 CMC
Tutwiler, MS
Services:
Walls · 1 center

Desoto County Treatment Center
Walls, MS
Services:
Water Valley · 1 center

Communicare
Water Valley, MS
Services:
Whitfield · 1 center

Mississippi State Hospital
Whitfield, MS
Services:
Showing 43 of 48 buprenorphine providers in Mississippi. Browse all centers in Mississippi
Frequently Asked Questions About Buprenorphine in Mississippi
Is buprenorphine only for heroin or fentanyl use, or does it also treat prescription opioid dependence?
buprenorphine is approved for opioid use disorder involving any opioid — heroin, fentanyl, prescription oxycodone, hydrocodone, or morphine. Mississippi clinicians treat patients whose OUD started with a pain prescription just as readily as those using illicit opioids.
Do buprenorphine providers in Mississippi offer sliding-scale fees?
Many Mississippi community behavioral-health agencies and federally qualified health centers offer sliding-scale fees based on household income. Sliding-scale fees commonly bring a weekly methadone visit down to $5–$25. Ask buprenorphine providers in your area about discounted rates when you call.
Do I need prior authorization for buprenorphine under Mississippi Medicaid?
Most Mississippi Medicaid plans have eliminated prior authorization for MAT medications, but long-acting injectables like Sublocade and Vivitrol may still require PA. Your Mississippi provider’s billing staff will handle any authorizations needed before your first dose.
Does Blue Cross Blue Shield cover buprenorphine in Mississippi?
Yes. Blue Cross Blue Shield plans in Mississippi cover all three FDA-approved MAT medications. BCBS typically requires the provider to be in-network; most major buprenorphine providers in Jackson and across Mississippi accept BCBS.
Are drug courts in Mississippi allowed to ban buprenorphine?
No. A 2022 Department of Justice enforcement action confirmed that Mississippi drug courts cannot ban FDA-approved MAT medications; doing so violates the ADA. Patients in drug court have the legal right to remain on their prescribed buprenorphine regimen.
How long does buprenorphine treatment typically last in Mississippi?
Many Mississippi patients stay on buprenorphine for a year or more, and some stay indefinitely. Duration depends on individual stability, quality of life, and risk of relapse. Research consistently shows that longer MAT duration is associated with lower overdose mortality.
Can I start buprenorphine the same day I call?
Same-day induction is increasingly common in Mississippi — especially for buprenorphine at low-barrier clinics and in emergency departments. Methadone same-day starts depend on OTP capacity; call early in the day to maximize your chance of same-day intake.
Will I feel high or sedated after the first buprenorphine dose?
Most patients feel calm relief of withdrawal rather than euphoria. Mild drowsiness is common the first day; avoid driving or operating machinery until you know how you react. Severe sedation is rare and warrants a call to the Mississippi clinic.
Is long-term buprenorphine safe?
Yes. Decades of research support the long-term safety of methadone, buprenorphine, and naltrexone when appropriately prescribed. Long-term MAT is associated with lower mortality, reduced infectious disease, and improved quality of life. Mississippi patients frequently remain on MAT for years without medical complications.
Does Mississippi have perinatal-MAT programs?
Yes. Most Mississippi regions have perinatal-addiction programs coordinating OB care, MAT, and social support. Call 988 or SAMHSA 1-800-662-4357 for Mississippi-specific referral. Jackson-area hospitals typically have dedicated perinatal-addiction coordinators.
Will my counseling sessions be confidential?
Yes — counseling records are protected by 42 CFR Part 2 and HIPAA. The counselor cannot disclose your MAT status or session content to family, employer, or law enforcement without your specific written consent or a narrowly tailored court order.
Do my pharmacy records show that I’m on buprenorphine in Mississippi?
Buprenorphine and naltrexone prescriptions appear on pharmacy records like other prescriptions and are visible to dispensing pharmacies and authorized users of the PDMP. Methadone dispensed at an OTP is not reported to retail pharmacy systems.
Other Treatment Options in Mississippi
Buprenorphine Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)

