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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Buprenorphine Treatment Centers in Mississippi

Medically reviewed by NWVCIL Editorial TeamLast reviewed: May 2026

Our directory lists 48 buprenorphine providers across Mississippi, with the largest concentrations in Jackson (5), Oxford (3) and Meridian (3).

Mississippi had 702 drug overdose deaths in 2023 — a 25.3-per-100,000 age-adjusted rate — and the state's MAT landscape has a notable structural gap: Mississippi Medicaid does not currently reimburse methadone for opioid use disorder. This means that buprenorphine and naltrexone, which can be prescribed in standard outpatient settings, are the primary medications available to Medicaid members, while methadone access depends on the 4 SAMHSA-certified Opioid Treatment Programs operating statewide. NWVCIL's directory tracks 43 buprenorphine providers in Mississippi, with 5 in Jackson, 3 in Corinth, and 3 in Meridian. The Mississippi Department of Mental Health oversees OTP licensing in addition to SAMHSA certification, and the state has invested in expanding office-based buprenorphine access through community mental-health centers and FQHCs. 55 of the 82 verified facilities in our directory accept Medicaid, and 47 offer telehealth. The relative scarcity of in-person specialists outside Jackson makes telehealth-delivered buprenorphine particularly important for Delta and Pine Belt residents. For a Mississippian starting buprenorphine, common pathways include: an intake at a community mental-health center in one of the state's 14 regions, a Federally Qualified Health Center for sliding-fee or Medicaid patients, a private MAT clinic in Jackson, Tupelo, or the Gulf Coast, or a telehealth visit with a Mississippi-licensed prescriber. Most providers can prescribe Suboxone, Subutex, Zubsolv, or the monthly Sublocade injection. SAMHSA's national helpline (1-800-662-4357), the 988 Suicide and Crisis Lifeline, and the Mississippi Department of Mental Health Helpline (1-877-210-8513) are available 24/7.

Treatment landscape in Mississippi:

  • Mississippi recorded 702 drug overdose deaths in 2023 at 25.3 per 100,000 (CDC NCHS).
  • 43 buprenorphine providers and 4 methadone Opioid Treatment Programs serve the state; Jackson, Corinth, and Meridian anchor access.
  • Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.
  • The state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.

Buprenorphine in Mississippi — By the Numbers

25.3

per 100,000 drug overdose mortality (CDC 2023)

702

total overdose deaths in Mississippi (2023)

43

buprenorphine providers in our directory

47 / 82

facilities offering telehealth

55

accept Medicaid for treatment

4

SAMHSA-certified Opioid Treatment Programs

Top cities by buprenorphine provider density

Jackson (5) · Corinth (3) · Meridian (3)

Sources: CDC NCHS Drug Overdose Mortality (2023) · SAMHSA Treatment Locator · NWVCIL directory snapshot, May 2026

Coverage & Regulations in MississippiSources verified: 2026-05-14

Mississippi Medicaid

Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.

State regulations

Mississippi has a limited OTP network; the state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.

SAMHSA National Helpline: 1-800-662-4357Crisis: 988
Commonly Accepted Insurance in Mississippi
  • Cash or self-payment42
  • Federal, or any government funding for substance use treatment programs32
  • Private health insurance28
  • SAMHSA funding/block grants27
  • Medicaid26
  • Federal military insurance (e.g., TRICARE)24
Available Treatment Settings in Mississippi
  • Outpatient32
  • Regular outpatient treatment31
  • Outpatient methadone/buprenorphine or naltrexone treatment24
  • Intensive outpatient treatment20
  • Residential/24-hour residential19

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Buprenorphine Treatment Providers in Mississippi

Buprenorphine providers in Mississippi

Filters:

Jackson · 5 centers

Jackson Comprehensive Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Hinds Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more
Jackson VAMC GV Sonny Montgomery - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Corinth · 3 centers

Region IV MHS - Facility Image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Meridian · 3 centers

HamiltonDavis Treatment Services - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image

A Second Chance

Meridian, MS

$$

Services:

Substance use treatment
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Oxford · 3 centers

Oxford Outpatient Treatment Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home
Placeholder image

Communicare

Oxford, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing
Placeholder image

Communicare

Oxford, MS

Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Biloxi · 2 centers

Mississippi Drug and Alcohol - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more
Biloxi Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Byram · 2 centers

Harbor Houses of Jackson Inc - Facility Image
$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home
Sign language services for the deaf and hard of hearing
Harbor Houses of Jackson Inc - Facility Image
$$

Services:

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home
Sign language services for the deaf and hard of hearing

Columbus · 2 centers

Recovery House - Facility Image

Recovery House

Columbus, MS

$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hattiesburg · 2 centers

Pine Grove BH and Addiction Servs - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

PBMHR Region XII

Hattiesburg, MS

Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Vicksburg · 2 centers

Belmont Gardens Recovery Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
$$

Services:

DetoxificationSubstance use treatment

Brandon · 1 center

Defining Wellness Centers - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Etta · 1 center

Oxford Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment
Sign language services for the deaf and hard of hearing

Greenwood · 1 center

Placeholder image

Denton House CDC

Greenwood, MS

$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hernando · 1 center

Region 4 Desoto - Facility Image

Region 4 Desoto

Hernando, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Holly Springs · 1 center

Placeholder image

Communicare

Holly Springs, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Laurel · 1 center

Pathway Healthcare Laurel - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Moselle · 1 center

Placeholder image

PBMHR Region XII

Moselle, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Pascagoula · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Pittsboro · 1 center

Placeholder image

Communicare

Pittsboro, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Purvis · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing+1 more

Ridgeland · 1 center

Placeholder image
$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Sardis · 1 center

Communicare - Facility Image

Communicare

Sardis, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Senatobia · 1 center

Placeholder image

Communicare

Senatobia, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Summit · 1 center

PBMHR Region XII - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Tupelo · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Tutwiler · 1 center

Placeholder image
$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Walls · 1 center

Desoto County Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Water Valley · 1 center

Placeholder image

Communicare

Water Valley, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sign language services for the deaf and hard of hearing

Whitfield · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Showing 43 of 48 buprenorphine providers in Mississippi. Browse all centers in Mississippi

Frequently Asked Questions About Buprenorphine in Mississippi

Is buprenorphine only for heroin or fentanyl use, or does it also treat prescription opioid dependence?

buprenorphine is approved for opioid use disorder involving any opioid — heroin, fentanyl, prescription oxycodone, hydrocodone, or morphine. Mississippi clinicians treat patients whose OUD started with a pain prescription just as readily as those using illicit opioids.

Do buprenorphine providers in Mississippi offer sliding-scale fees?

Many Mississippi community behavioral-health agencies and federally qualified health centers offer sliding-scale fees based on household income. Sliding-scale fees commonly bring a weekly methadone visit down to $5–$25. Ask buprenorphine providers in your area about discounted rates when you call.

Do I need prior authorization for buprenorphine under Mississippi Medicaid?

Most Mississippi Medicaid plans have eliminated prior authorization for MAT medications, but long-acting injectables like Sublocade and Vivitrol may still require PA. Your Mississippi provider’s billing staff will handle any authorizations needed before your first dose.

Does Blue Cross Blue Shield cover buprenorphine in Mississippi?

Yes. Blue Cross Blue Shield plans in Mississippi cover all three FDA-approved MAT medications. BCBS typically requires the provider to be in-network; most major buprenorphine providers in Jackson and across Mississippi accept BCBS.

Are drug courts in Mississippi allowed to ban buprenorphine?

No. A 2022 Department of Justice enforcement action confirmed that Mississippi drug courts cannot ban FDA-approved MAT medications; doing so violates the ADA. Patients in drug court have the legal right to remain on their prescribed buprenorphine regimen.

How long does buprenorphine treatment typically last in Mississippi?

Many Mississippi patients stay on buprenorphine for a year or more, and some stay indefinitely. Duration depends on individual stability, quality of life, and risk of relapse. Research consistently shows that longer MAT duration is associated with lower overdose mortality.

Can I start buprenorphine the same day I call?

Same-day induction is increasingly common in Mississippi — especially for buprenorphine at low-barrier clinics and in emergency departments. Methadone same-day starts depend on OTP capacity; call early in the day to maximize your chance of same-day intake.

Will I feel high or sedated after the first buprenorphine dose?

Most patients feel calm relief of withdrawal rather than euphoria. Mild drowsiness is common the first day; avoid driving or operating machinery until you know how you react. Severe sedation is rare and warrants a call to the Mississippi clinic.

Is long-term buprenorphine safe?

Yes. Decades of research support the long-term safety of methadone, buprenorphine, and naltrexone when appropriately prescribed. Long-term MAT is associated with lower mortality, reduced infectious disease, and improved quality of life. Mississippi patients frequently remain on MAT for years without medical complications.

Does Mississippi have perinatal-MAT programs?

Yes. Most Mississippi regions have perinatal-addiction programs coordinating OB care, MAT, and social support. Call 988 or SAMHSA 1-800-662-4357 for Mississippi-specific referral. Jackson-area hospitals typically have dedicated perinatal-addiction coordinators.

Will my counseling sessions be confidential?

Yes — counseling records are protected by 42 CFR Part 2 and HIPAA. The counselor cannot disclose your MAT status or session content to family, employer, or law enforcement without your specific written consent or a narrowly tailored court order.

Do my pharmacy records show that I’m on buprenorphine in Mississippi?

Buprenorphine and naltrexone prescriptions appear on pharmacy records like other prescriptions and are visible to dispensing pharmacies and authorized users of the PDMP. Methadone dispensed at an OTP is not reported to retail pharmacy systems.

Other Treatment Options in Mississippi

Buprenorphine Treatment in Other States

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)