Naltrexone Treatment Centers in Mississippi
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 48 naltrexone providers across Mississippi, with the largest concentrations in Jackson (5), Oxford (3) and Corinth (3).
Naltrexone (Vivitrol, Revia) is an opioid antagonist used to treat both alcohol use disorder and opioid dependence. Available as a daily oral tablet or monthly extended-release injection, it blocks opioid receptors to reduce cravings and prevent relapse.
Treatment landscape in Mississippi:
- Mississippi Medicaid covers substance abuse services
- Faith-based recovery community
- Affordable treatment options throughout the state
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Naltrexone providers in Mississippi
Jackson · 5 centers

Jackson Comprehensive Treatment Center
Jackson, MS
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Hinds Behavioral Health Services
Jackson, MS
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Jackson VAMC GV Sonny Montgomery
Jackson, MS
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Pathway Healthcare
Jackson, MS
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Corinth · 3 centers

Region IV MHS
Corinth, MS
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Region IV MHS
Corinth, MS
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Region IV MHS
Corinth, MS
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Oxford · 3 centers

Oxford Outpatient Treatment Center
Oxford, MS
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Communicare
Oxford, MS
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Communicare
Oxford, MS
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Brandon · 2 centers

Defining Wellness Centers
Brandon, MS
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Region 8 Mental Health Services
Brandon, MS
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Byram · 2 centers

Harbor Houses of Jackson Inc
Byram, MS
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Harbor Houses of Jackson Inc
Byram, MS
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Columbus · 2 centers

Recovery House
Columbus, MS
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Pines and Cady Hill
Columbus, MS
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Hattiesburg · 2 centers

Pine Grove BH and Addiction Servs
Hattiesburg, MS
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PBMHR Region XII
Hattiesburg, MS
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Meridian · 2 centers

HamiltonDavis Treatment Services
Meridian, MS
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Weems Community MH Center
Meridian, MS
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Vicksburg · 2 centers

Belmont Gardens Recovery Center
Vicksburg, MS
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Biloxi · 1 center

Mississippi Drug and Alcohol
Biloxi, MS
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Brookhaven · 1 center

Region 8 Mental Health Services
Brookhaven, MS
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Canton · 1 center

Region 8 Mental Health Services
Canton, MS
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Carthage · 1 center

Weems Community MH Center
Carthage, MS
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Decatur · 1 center

Weems Community MH Center
Decatur, MS
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Etta · 1 center
Forest · 1 center

Weems Community MH Center
Forest, MS
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Greenwood · 1 center

Denton House CDC
Greenwood, MS
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Hazlehurst · 1 center

Region 8 Mental Health Services
Hazlehurst, MS
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Hernando · 1 center

Region 4 Desoto
Hernando, MS
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Holly Springs · 1 center

Communicare
Holly Springs, MS
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Laurel · 1 center

Pathway Healthcare Laurel
Laurel, MS
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Moselle · 1 center

PBMHR Region XII
Moselle, MS
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Philadelphia · 1 center

Weems Community MH Center
Philadelphia, MS
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Pittsboro · 1 center

Communicare
Pittsboro, MS
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Quitman · 1 center

Weems Community MH Center
Quitman, MS
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Raleigh · 1 center

Weems Community MH Center
Raleigh, MS
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Ridgeland · 1 center

Essential Touchstones
Ridgeland, MS
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Sardis · 1 center

Communicare
Sardis, MS
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Senatobia · 1 center

Communicare
Senatobia, MS
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Summit · 1 center

PBMHR Region XII
Summit, MS
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Tupelo · 1 center

Region III Chem Dependency
Tupelo, MS
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Tutwiler · 1 center

Life Help/Region 6 CMC
Tutwiler, MS
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Water Valley · 1 center

Communicare
Water Valley, MS
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Whitfield · 1 center

Mississippi State Hospital
Whitfield, MS
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Mississippi Medicaid
Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.
State regulations
Mississippi has a limited OTP network; the state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.
- Cash or self-payment47
- Federal, or any government funding for substance use treatment programs38
- SAMHSA funding/block grants36
- Private health insurance34
- Medicaid32
- Federal military insurance (e.g., TRICARE)28
- Outpatient38
- Regular outpatient treatment37
- Intensive outpatient treatment21
- Outpatient methadone/buprenorphine or naltrexone treatment20
- Residential/24-hour residential19
Frequently Asked Questions About Naltrexone in Mississippi
Do I need insurance to enroll in naltrexone treatment?
No. You can pay out of pocket, use Mississippi Medicaid if eligible, or qualify for sliding-scale rates at many Mississippi federally qualified health centers. Uninsured patients should still call naltrexone providers to ask about grant-funded slots and state-funded treatment vouchers.
How much does Vivitrol (naltrexone injection) cost without insurance?
Vivitrol monthly cost without insurance typically falls between $1,100 and $1,500 per injection in Mississippi. The manufacturer Alkermes offers a patient-assistance co-pay savings card; state-funded programs also cover Vivitrol for uninsured patients in many counties.
If I lose Medicaid, can I still continue naltrexone in Mississippi?
Yes — federally qualified health centers and State Opioid Response–funded naltrexone providers in Mississippi continue treatment during coverage gaps. Ask your clinic about sliding-scale fees and grant slots the moment your Mississippi Medicaid renewal lapses; don’t stop the medication abruptly.
Can I use an HSA or FSA to pay for naltrexone in Mississippi?
Yes. HSA and FSA funds are eligible for all MAT out-of-pocket expenses — copays, medication, counseling, lab tests — because MAT is IRS-qualified medical care. Keep itemized receipts from naltrexone providers for tax records.
Does Mississippi allow telehealth induction for MAT?
Yes. DEA rules were permanently expanded in 2024 to allow audio-video telehealth for initial buprenorphine prescribing, and Mississippi law mirrors federal policy. Methadone induction still requires an in-person visit at an OTP for the first dose, though subsequent counseling can be delivered via telehealth. Naltrexone can be prescribed via telehealth with labs done in Mississippi.
Can I go back on naltrexone after stopping?
Yes. Returning to naltrexone after a gap in care is common and safe; your Mississippi clinic will re-induct using the same protocols as first-time patients. The federal 1-year waiting period sometimes referenced for methadone does not apply to re-admission.
How long is the waitlist for naltrexone in Mississippi?
Most Mississippi naltrexone providers offer intake within 3 business days; urban programs in Jackson typically offer same-day access. State Opioid Response funding has targeted waitlist reduction, and many counties now operate 24/7 bridge lines for urgent access.
Is the first naltrexone visit confidential?
Yes. Records are protected by 42 CFR Part 2, which is stricter than HIPAA. Your employer, family, or law enforcement cannot access your records without your specific written consent or a narrowly tailored court order. Confidentiality applies from the first visit onward.
Are there allergic reactions to naltrexone?
True allergic reactions to methadone, buprenorphine, or naltrexone are rare. Rash, swelling, or difficulty breathing after a dose should be treated as an emergency — call 911 or go to a Mississippi emergency department. The MAT team can switch medications after stabilization.
Should I stop naltrexone when I find out I’m pregnant?
No — abrupt discontinuation is dangerous for the pregnancy. Call your Mississippi MAT clinic right away; the team will coordinate with obstetrics to continue medication safely and arrange any dose adjustments needed as the pregnancy progresses.
Do I have to attend 12-step meetings along with naltrexone?
No. Attending 12-step programs is optional; SMART Recovery, Women for Sobriety, Refuge Recovery, and secular support groups are all acceptable alternatives. Mississippi MAT clinicians can help you match with a peer group aligned to your values.
Are my naltrexone records confidential in Mississippi?
Yes. Your records are protected by federal law 42 CFR Part 2, which is stricter than HIPAA. Disclosure requires your signed consent or a specific court order; even law enforcement cannot access records without one of these.
Other Treatment Options in Mississippi
Naltrexone Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)

