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Medically Reviewed Content
Updated: April 2026
Sources: SAMHSA, NIDA

Naltrexone Treatment Centers in Mississippi

Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026

Our directory lists 48 naltrexone providers across Mississippi, with the largest concentrations in Jackson (5), Oxford (3) and Corinth (3).

Naltrexone (Vivitrol, Revia) is an opioid antagonist used to treat both alcohol use disorder and opioid dependence. Available as a daily oral tablet or monthly extended-release injection, it blocks opioid receptors to reduce cravings and prevent relapse.

Treatment landscape in Mississippi:

  • Mississippi Medicaid covers substance abuse services
  • Faith-based recovery community
  • Affordable treatment options throughout the state

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Naltrexone providers in Mississippi

Filters:

Jackson · 5 centers

Jackson Comprehensive Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Hinds Behavioral Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Jackson VAMC GV Sonny Montgomery - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Corinth · 3 centers

Region IV MHS - Facility Image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

Region IV MHS

Corinth, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Oxford · 3 centers

Oxford Outpatient Treatment Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home
Placeholder image

Communicare

Oxford, MS

Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

Communicare

Oxford, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Brandon · 2 centers

Defining Wellness Centers - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Byram · 2 centers

Harbor Houses of Jackson Inc - Facility Image
$$

Services:

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home
Harbor Houses of Jackson Inc - Facility Image
$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober home

Columbus · 2 centers

Recovery House - Facility Image

Recovery House

Columbus, MS

$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hattiesburg · 2 centers

Pine Grove BH and Addiction Servs - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image

PBMHR Region XII

Hattiesburg, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Meridian · 2 centers

HamiltonDavis Treatment Services - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Vicksburg · 2 centers

Belmont Gardens Recovery Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Placeholder image
$$

Services:

DetoxificationSubstance use treatment

Biloxi · 1 center

Mississippi Drug and Alcohol - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Brookhaven · 1 center

Region 8 Mental Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Canton · 1 center

Region 8 Mental Health Services - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Carthage · 1 center

Weems Community MH Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Decatur · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Etta · 1 center

Oxford Treatment Center - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatment

Forest · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Greenwood · 1 center

Placeholder image

Denton House CDC

Greenwood, MS

$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hazlehurst · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Hernando · 1 center

Region 4 Desoto - Facility Image

Region 4 Desoto

Hernando, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Holly Springs · 1 center

Placeholder image

Communicare

Holly Springs, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Laurel · 1 center

Pathway Healthcare Laurel - Facility Image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Moselle · 1 center

Placeholder image

PBMHR Region XII

Moselle, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Philadelphia · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Pittsboro · 1 center

Placeholder image

Communicare

Pittsboro, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Quitman · 1 center

Weems Community MH Center - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Raleigh · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Ridgeland · 1 center

Placeholder image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Sardis · 1 center

Communicare - Facility Image

Communicare

Sardis, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Senatobia · 1 center

Placeholder image

Communicare

Senatobia, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Summit · 1 center

PBMHR Region XII - Facility Image
Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Tupelo · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Tutwiler · 1 center

Placeholder image
$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Water Valley · 1 center

Placeholder image

Communicare

Water Valley, MS

Insurance Accepted$$

Services:

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Whitfield · 1 center

Placeholder image
Insurance Accepted$$

Services:

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Coverage & Regulations in Mississippi

Mississippi Medicaid

Mississippi Medicaid covers buprenorphine and naltrexone for opioid use disorder; the state does not currently reimburse methadone for OUD through Medicaid.

State regulations

Mississippi has a limited OTP network; the state Department of Mental Health oversees OTP licensing in addition to SAMHSA certification.

SAMHSA National Helpline: 1-800-662-4357Crisis: 988
Commonly Accepted Insurance
  • Cash or self-payment47
  • Federal, or any government funding for substance use treatment programs38
  • SAMHSA funding/block grants36
  • Private health insurance34
  • Medicaid32
  • Federal military insurance (e.g., TRICARE)28
Available Settings
  • Outpatient38
  • Regular outpatient treatment37
  • Intensive outpatient treatment21
  • Outpatient methadone/buprenorphine or naltrexone treatment20
  • Residential/24-hour residential19

Frequently Asked Questions About Naltrexone in Mississippi

Do I need insurance to enroll in naltrexone treatment?

No. You can pay out of pocket, use Mississippi Medicaid if eligible, or qualify for sliding-scale rates at many Mississippi federally qualified health centers. Uninsured patients should still call naltrexone providers to ask about grant-funded slots and state-funded treatment vouchers.

How much does Vivitrol (naltrexone injection) cost without insurance?

Vivitrol monthly cost without insurance typically falls between $1,100 and $1,500 per injection in Mississippi. The manufacturer Alkermes offers a patient-assistance co-pay savings card; state-funded programs also cover Vivitrol for uninsured patients in many counties.

If I lose Medicaid, can I still continue naltrexone in Mississippi?

Yes — federally qualified health centers and State Opioid Response–funded naltrexone providers in Mississippi continue treatment during coverage gaps. Ask your clinic about sliding-scale fees and grant slots the moment your Mississippi Medicaid renewal lapses; don’t stop the medication abruptly.

Can I use an HSA or FSA to pay for naltrexone in Mississippi?

Yes. HSA and FSA funds are eligible for all MAT out-of-pocket expenses — copays, medication, counseling, lab tests — because MAT is IRS-qualified medical care. Keep itemized receipts from naltrexone providers for tax records.

Does Mississippi allow telehealth induction for MAT?

Yes. DEA rules were permanently expanded in 2024 to allow audio-video telehealth for initial buprenorphine prescribing, and Mississippi law mirrors federal policy. Methadone induction still requires an in-person visit at an OTP for the first dose, though subsequent counseling can be delivered via telehealth. Naltrexone can be prescribed via telehealth with labs done in Mississippi.

Can I go back on naltrexone after stopping?

Yes. Returning to naltrexone after a gap in care is common and safe; your Mississippi clinic will re-induct using the same protocols as first-time patients. The federal 1-year waiting period sometimes referenced for methadone does not apply to re-admission.

How long is the waitlist for naltrexone in Mississippi?

Most Mississippi naltrexone providers offer intake within 3 business days; urban programs in Jackson typically offer same-day access. State Opioid Response funding has targeted waitlist reduction, and many counties now operate 24/7 bridge lines for urgent access.

Is the first naltrexone visit confidential?

Yes. Records are protected by 42 CFR Part 2, which is stricter than HIPAA. Your employer, family, or law enforcement cannot access your records without your specific written consent or a narrowly tailored court order. Confidentiality applies from the first visit onward.

Are there allergic reactions to naltrexone?

True allergic reactions to methadone, buprenorphine, or naltrexone are rare. Rash, swelling, or difficulty breathing after a dose should be treated as an emergency — call 911 or go to a Mississippi emergency department. The MAT team can switch medications after stabilization.

Should I stop naltrexone when I find out I’m pregnant?

No — abrupt discontinuation is dangerous for the pregnancy. Call your Mississippi MAT clinic right away; the team will coordinate with obstetrics to continue medication safely and arrange any dose adjustments needed as the pregnancy progresses.

Do I have to attend 12-step meetings along with naltrexone?

No. Attending 12-step programs is optional; SMART Recovery, Women for Sobriety, Refuge Recovery, and secular support groups are all acceptable alternatives. Mississippi MAT clinicians can help you match with a peer group aligned to your values.

Are my naltrexone records confidential in Mississippi?

Yes. Your records are protected by federal law 42 CFR Part 2, which is stricter than HIPAA. Disclosure requires your signed consent or a specific court order; even law enforcement cannot access records without one of these.

Other Treatment Options in Mississippi

Naltrexone Treatment in Other States

Medically Reviewed Updated April 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)