Buprenorphine Treatment Centers in Missouri
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 160 buprenorphine providers across Missouri, with the largest concentrations in Saint Louis (18), Kansas City (9) and Cape Girardeau (7).
Buprenorphine (Suboxone, Subutex, Sublocade, Zubsolv) is a partial opioid agonist that reduces cravings and withdrawal symptoms for opioid use disorder. It can be prescribed in outpatient settings by qualified clinicians.
Treatment landscape in Missouri:
- MO HealthNet covers addiction treatment
- Major treatment hubs in St. Louis and Kansas City
- Diverse treatment philosophies and approaches
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Buprenorphine providers in Missouri
Saint Louis · 18 centers

Care STL Health
Saint Louis, MO
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Carestl Health Pope
Saint Louis, MO
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Carestl Health Riverview
Saint Louis, MO
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Carestlhealth
Saint Louis, MO
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INSynergy Treatment Program
Saint Louis, MO
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Places for People
Saint Louis, MO
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Places for People
Saint Louis, MO
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St Louis Metro Treatment Center
Saint Louis, MO
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Saint Louis Veterans Affairs Med Ctr
Saint Louis, MO
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Queen of Peace Center
Saint Louis, MO
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Amanda Luckett Murphy Hopewell Center
Saint Louis, MO
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Aviary Recovery Center
Saint Louis, MO
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BJC Behavioral Health
Saint Louis, MO
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Gateway Foundation Inc
Saint Louis, MO
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BASIC
Saint Louis, MO
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Centrec Care
Saint Louis, MO
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Preferred Family Healthcare Inc
Saint Louis, MO
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Preferred Family Healthcare Inc
Saint Louis, MO
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Kansas City · 9 centers
Beacon Mental Health
Kansas City, MO
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Beacon Mental Health
Kansas City, MO
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Swope Health Services
Kansas City, MO
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ReDiscover
Kansas City, MO
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Heartland Center for Behavioral Change
Kansas City, MO
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ReDiscover
Kansas City, MO
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Sana Lake Behavioral Wellness Center
Kansas City, MO
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Cape Girardeau · 7 centers

Cape Girardeau Metro Treatment Ctr
Cape Girardeau, MO
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Vision House of Cape Girardeau
Cape Girardeau, MO
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Gibson Recovery Center Inc
Cape Girardeau, MO
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Gibson Recovery Center Inc
Cape Girardeau, MO
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Community Counseling Center
Cape Girardeau, MO
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Community Counseling Center
Cape Girardeau, MO
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Gibson Center for Behavioral Change
Cape Girardeau, MO
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Columbia · 5 centers

Harry S Truman Memorial
Columbia, MO
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Compass Health
Columbia, MO
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Compass Health
Columbia, MO
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Compass Health
Columbia, MO
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Joplin · 5 centers

BHG Joplin Treatment Center
Joplin, MO
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Ozark Center
Joplin, MO
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Ozark Center
Joplin, MO
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Ozark Center/New Directions
Joplin, MO
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Springfield · 5 centers

Synergy Counseling Center
Springfield, MO
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Center for Addictions
Springfield, MO
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Communities of Recovery Inc
Springfield, MO
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Poplar Bluff · 4 centers

BHG Poplar Bluff Treatment Center
Poplar Bluff, MO
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Southeast Missouri Behavioral Health
Poplar Bluff, MO
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Southeast Missouri Behavioral Health
Poplar Bluff, MO
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FCC Behavioral Health
Poplar Bluff, MO
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Farmington · 3 centers

BJC Behavioral Health
Farmington, MO
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Southeast Missouri Behavioral Health
Farmington, MO
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Southeast Missouri Behavioral Health
Farmington, MO
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Fredericktown · 3 centers

Community Counseling Center
Fredericktown, MO
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Community Counseling Center
Fredericktown, MO
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Community Counseling Center
Fredericktown, MO
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Hannibal · 3 centers

Mark Twain Behavioral Health
Hannibal, MO
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Mark Twain Behavioral Health
Hannibal, MO
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Preferred Family Healthcare Inc
Hannibal, MO
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Saint Joseph · 3 centers

Northwest Health Services
Saint Joseph, MO
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Family Guidance Center
Saint Joseph, MO
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St Kolbe Puckett Center for Healing
Saint Joseph, MO
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West Plains · 3 centers

BHG West Plains Treatment Center
West Plains, MO
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FCC Behavioral Health
West Plains, MO
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FCC Behavioral Health
West Plains, MO
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Boonville · 2 centers

Compass Health
Boonville, MO
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Valley Hope of Boonville
Boonville, MO
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Brookfield · 2 centers

North Central MO Mental Health Center
Brookfield, MO
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Preferred Family Healthcare Inc
Brookfield, MO
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Clinton · 2 centers

Compass Health
Clinton, MO
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Compass Health
Clinton, MO
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Florissant · 2 centers

BJC Behavioral Health
Florissant, MO
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Preferred Family Healthcare Inc
Florissant, MO
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Fulton · 2 centers

Compass Health
Fulton, MO
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Harrisonville · 2 centers

Comm Mental Health Consultants Inc
Harrisonville, MO
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Compass Health
Harrisonville, MO
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Marble Hill · 2 centers

Gibson Recovery Center Inc
Marble Hill, MO
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Community Counseling Center
Marble Hill, MO
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Moberly · 2 centers

Mark Twain Behavioral Health
Moberly, MO
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Preferred Family Healthcare Inc
Moberly, MO
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Nevada · 2 centers

Compass Health
Nevada, MO
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Comm Mental Health Consultants Inc
Nevada, MO
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Perryville · 2 centers

Community Counseling Center
Perryville, MO
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Gibson Recovery Center Inc
Perryville, MO
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Piedmont · 2 centers

FCC Behavioral Health
Piedmont, MO
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Southeast Missouri Behavioral Health
Piedmont, MO
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Raymore · 2 centers

Compass Health
Raymore, MO
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Compass Health
Raymore, MO
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Salem · 2 centers

Southeast Missouri Behavioral Health
Salem, MO
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Compass Health
Salem, MO
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Sikeston · 2 centers

Bootheel Counseling Services
Sikeston, MO
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Gibson Recovery Center Inc
Sikeston, MO
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Sullivan · 2 centers

Compass Health
Sullivan, MO
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Warrensburg · 2 centers

Compass Health
Warrensburg, MO
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Compass Health
Warrensburg, MO
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Wentzville · 2 centers

Compass Health
Wentzville, MO
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SSM Health Treatment and Recovery
Wentzville, MO
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Ava · 1 center

Family Counseling Center Inc
Ava, MO
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Ballwin · 1 center
Bowling Green · 1 center

Mark Twain Behavioral Health
Bowling Green, MO
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Branson · 1 center

Communities of Recovery Inc
Branson, MO
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Butler · 1 center

Compass Health
Butler, MO
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Cadet · 1 center

Southeast Missouri Behavioral Health
Cadet, MO
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Cameron · 1 center

Family Guidance Center/Cameron
Cameron, MO
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Canton · 1 center

Preferred Family Healthcare Inc
Canton, MO
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Caruthersville · 1 center

FCC Behavioral Health
Caruthersville, MO
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Cassville · 1 center

Clark Community Mental Health Center
Cassville, MO
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Charleston · 1 center

FCC Behavioral Health
Charleston, MO
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Chillicothe · 1 center

North Central MO Mental Health Center
Chillicothe, MO
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Dittmer · 1 center

Sana Lake Recovery
Dittmer, MO
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Doniphan · 1 center

FCC Behavioral Health
Doniphan, MO
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El Dorado Springs · 1 center

Compass Health
El Dorado Springs, MO
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Eldon · 1 center

Compass Health
Eldon, MO
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Ellington · 1 center

FCC Behavioral Health
Ellington, MO
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Eolia · 1 center

Aviary Recovery Center
Eolia, MO
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Greenfield · 1 center

Clark Community Mental Health Center
Greenfield, MO
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Greenville · 1 center

Family Counseling Center Inc
Greenville, MO
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Hayti · 1 center

Family Counseling Center Inc
Hayti, MO
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Higginsville · 1 center

Compass Health
Higginsville, MO
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Houston · 1 center

Southeast Missouri Behavioral Health
Houston, MO
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Jefferson City · 1 center

Compass Health
Jefferson City, MO
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Kahoka · 1 center

Preferred Family Healthcare Inc
Kahoka, MO
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Kennett · 1 center

FCC Behavioral Health
Kennett, MO
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Kirksville · 1 center

Preferred Family Healthcare Inc
Kirksville, MO
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Lebanon · 1 center
Lees Summit · 1 center

ReDiscover
Lees Summit, MO
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Liberty · 1 center

Heartland Center for Behavioral Change
Liberty, MO
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Linn Creek · 1 center

Compass Health
Linn Creek, MO
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Macon · 1 center

Preferred Family Healthcare Inc
Macon, MO
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Maryland Heights · 1 center

Sana Lake Behavioral Wellness
Maryland Heights, MO
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Maryville · 1 center

Family Guidance Center
Maryville, MO
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Mexico · 1 center

East Central MO Behavioral Health
Mexico, MO
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Monett · 1 center

Clark Community Mental Health Center
Monett, MO
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Montgomery City · 1 center

Arthur Center Community Health
Montgomery City, MO
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Mountain Grove · 1 center

Family Counseling Center Inc
Mountain Grove, MO
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Neosho · 1 center
Odessa · 1 center

Compass Health
Odessa, MO
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Osage Beach · 1 center

Compass Health
Osage Beach, MO
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Osceola · 1 center

Compass Health
Osceola, MO
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Owensville · 1 center

Compass Health
Owensville, MO
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Ozark · 1 center

Synergy Executive
Ozark, MO
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Richland · 1 center

Central Ozarks Medical Center
Richland, MO
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Richmond · 1 center

Tri County Mental Health Services
Richmond, MO
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Rolla · 1 center

Southeast Missouri Behavioral Health
Rolla, MO
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Saint Charles · 1 center

New Season St Charles Trt Center
Saint Charles, MO
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Saint Peters · 1 center

Preferred Family Healthcare Inc
Saint Peters, MO
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Sainte Genevieve · 1 center

Community Counseling Center
Sainte Genevieve, MO
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Sedalia · 1 center

Compass Health Network Inc
Sedalia, MO
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Steelville · 1 center

Southeast Missouri Behavioral Health
Steelville, MO
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Trenton · 1 center

Preferred Family Healthcare Inc
Trenton, MO
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Troy · 1 center

Preferred Family Healthcare Inc
Troy, MO
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Union · 1 center

Preferred Family Healthcare Inc
Union, MO
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Van Buren · 1 center

FCC Behavioral Health
Van Buren, MO
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Warrenton · 1 center

Preferred Family Healthcare
Warrenton, MO
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Warsaw · 1 center

Compass Health
Warsaw, MO
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MO HealthNet
MO HealthNet covers MAT medications and funds MAT induction in jails and emergency departments through state general-fund grants.
State regulations
Missouri Department of Mental Health (DMH) licenses OTPs under 9 CSR 30-3 and funds a Medication First program giving same-day buprenorphine.
- Cash or self-payment152
- Private health insurance148
- Medicaid145
- Federal military insurance (e.g., TRICARE)127
- Medicare120
- Federal, or any government funding for substance use treatment programs115
- Outpatient148
- Regular outpatient treatment144
- Outpatient methadone/buprenorphine or naltrexone treatment124
- Intensive outpatient treatment76
- Outpatient day treatment or partial hospitalization40
Frequently Asked Questions About Buprenorphine in Missouri
Do I need to provide a criminal-history check to enroll in buprenorphine providers in Missouri?
No. Missouri MAT providers do not require criminal-history disclosure to enroll. Federal law (42 CFR Part 2) protects substance-use treatment records; a criminal record will not block admission to a buprenorphine program.
What is included in the monthly cost of buprenorphine?
Typical monthly cost covers the medication itself, counseling or group sessions, routine drug screening, and clinic visits. Additional costs may apply for initial lab work, ECG (for methadone), or long-acting injectable administration. Ask buprenorphine providers for an itemized fee schedule in writing.
What’s the difference between MO HealthNet managed-care plans for MAT?
MO HealthNet managed-care organizations (MCOs) in Missouri all cover MAT, but formulary details, prior-authorization rules, and in-network provider lists vary. Choose the MCO whose network includes your preferred buprenorphine providers; you can usually switch plans once a year.
Do I need a referral from my primary care doctor to start buprenorphine?
Most Missouri commercial plans do not require a PCP referral for behavioral-health or MAT services; you can typically self-refer to a buprenorphine provider. HMO plans may require a referral — check your plan’s Summary of Benefits.
Are there advocacy organizations for buprenorphine patients in Missouri?
Yes. Faces & Voices of Recovery chapters, the American Society of Addiction Medicine (ASAM) regional sections, and Missouri-based recovery community organizations advocate for patient rights. SAMHSA’s Recovery Community Services Program funds peer-led groups in most Missouri counties.
Is it harder to quit methadone than buprenorphine?
Methadone tapering generally takes longer than buprenorphine because of its long half-life and higher cumulative-dose equilibrium. Most Missouri clinicians taper methadone over 6–12 months or longer. Buprenorphine tapers often complete in 3–6 months for stable patients.
What should I avoid before my first buprenorphine visit?
Avoid benzodiazepines, alcohol, and long-acting opioids for 6–12 hours before induction to reduce sedation risk. For buprenorphine, let the clinician know your last opioid use time so they can time the first dose to avoid precipitated withdrawal.
Is the first buprenorphine dose stronger or weaker than later doses?
First doses are intentionally cautious — 5–10 mg of buprenorphine or 20–30 mg of methadone — to assess tolerance and avoid over-sedation. Your dose is titrated up over the first 1–2 weeks until cravings and withdrawal are controlled.
Can buprenorphine cause an overdose?
Methadone carries overdose risk during induction when the dose is being titrated, particularly in combination with benzodiazepines, alcohol, or other sedatives. Buprenorphine has a ceiling effect that lowers overdose risk. Naltrexone does not cause opioid overdose. Your Missouri clinic monitors risk closely.
What pain medication can I receive during delivery while on buprenorphine?
Standard labor epidurals are fully compatible with MAT. If post-operative opioid pain relief is needed after cesarean, higher doses may be required due to tolerance. The Missouri anesthesiology and MAT teams coordinate the post-operative pain plan before delivery.
Can I skip counseling and just take buprenorphine?
Patients prescribed buprenorphine or naltrexone in Missouri can technically receive medication without counseling, but outcomes are significantly better with integrated counseling. Methadone patients at OTPs have counseling requirements per federal rule 42 CFR Part 8.
Do my pharmacy records show that I’m on buprenorphine in Missouri?
Buprenorphine and naltrexone prescriptions appear on pharmacy records like other prescriptions and are visible to dispensing pharmacies and authorized users of the PDMP. Methadone dispensed at an OTP is not reported to retail pharmacy systems.
Other Treatment Options in Missouri
Buprenorphine Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)





