Naltrexone Treatment Centers in Missouri
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 159 naltrexone providers across Missouri, with the largest concentrations in Saint Louis (17), Kansas City (10) and Cape Girardeau (6).
Naltrexone (Vivitrol, Revia) is an opioid antagonist used to treat both alcohol use disorder and opioid dependence. Available as a daily oral tablet or monthly extended-release injection, it blocks opioid receptors to reduce cravings and prevent relapse.
Treatment landscape in Missouri:
- MO HealthNet covers addiction treatment
- Major treatment hubs in St. Louis and Kansas City
- Diverse treatment philosophies and approaches
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Naltrexone providers in Missouri
Saint Louis · 17 centers

Care STL Health
Saint Louis, MO
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Carestl Health Pope
Saint Louis, MO
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Carestl Health Riverview
Saint Louis, MO
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Carestlhealth
Saint Louis, MO
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INSynergy Treatment Program
Saint Louis, MO
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Places for People
Saint Louis, MO
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Places for People
Saint Louis, MO
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Saint Louis Veterans Affairs Med Ctr
Saint Louis, MO
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Queen of Peace Center
Saint Louis, MO
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Aviary Recovery Center
Saint Louis, MO
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BJC Behavioral Health
Saint Louis, MO
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Gateway Foundation Inc
Saint Louis, MO
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BASIC
Saint Louis, MO
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Centrec Care
Saint Louis, MO
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Preferred Family Healthcare Inc
Saint Louis, MO
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Preferred Family Healthcare Inc
Saint Louis, MO
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Preferred Family Healthcare Inc
Saint Louis, MO
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Kansas City · 10 centers
Beacon Mental Health
Kansas City, MO
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Beacon Mental Health
Kansas City, MO
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Swope Health Services
Kansas City, MO
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ReDiscover
Kansas City, MO
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Heartland Center for Behavioral Change
Kansas City, MO
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Preferred Family Healthcare Inc
Kansas City, MO
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ReDiscover
Kansas City, MO
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Sana Lake Behavioral Wellness Center
Kansas City, MO
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Cape Girardeau · 6 centers

Vision House of Cape Girardeau
Cape Girardeau, MO
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Gibson Recovery Center Inc
Cape Girardeau, MO
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Gibson Recovery Center Inc
Cape Girardeau, MO
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Community Counseling Center
Cape Girardeau, MO
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Community Counseling Center
Cape Girardeau, MO
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Gibson Center for Behavioral Change
Cape Girardeau, MO
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Joplin · 5 centers

BHG Joplin Treatment Center
Joplin, MO
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Ozark Center
Joplin, MO
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Ozark Center
Joplin, MO
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Ozark Center/New Directions
Joplin, MO
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Springfield · 5 centers

Synergy Counseling Center
Springfield, MO
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Center for Addictions
Springfield, MO
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Communities of Recovery Inc
Springfield, MO
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Columbia · 4 centers

Harry S Truman Memorial
Columbia, MO
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Compass Health
Columbia, MO
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Compass Health
Columbia, MO
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Compass Health
Columbia, MO
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Farmington · 3 centers

BJC Behavioral Health
Farmington, MO
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Southeast Missouri Behavioral Health
Farmington, MO
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Southeast Missouri Behavioral Health
Farmington, MO
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Fredericktown · 3 centers

Community Counseling Center
Fredericktown, MO
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Community Counseling Center
Fredericktown, MO
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Community Counseling Center
Fredericktown, MO
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Hannibal · 3 centers

Mark Twain Behavioral Health
Hannibal, MO
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Mark Twain Behavioral Health
Hannibal, MO
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Preferred Family Healthcare Inc
Hannibal, MO
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Poplar Bluff · 3 centers

Southeast Missouri Behavioral Health
Poplar Bluff, MO
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Southeast Missouri Behavioral Health
Poplar Bluff, MO
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FCC Behavioral Health
Poplar Bluff, MO
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Boonville · 2 centers

Compass Health
Boonville, MO
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Valley Hope of Boonville
Boonville, MO
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Brookfield · 2 centers

North Central MO Mental Health Center
Brookfield, MO
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Preferred Family Healthcare Inc
Brookfield, MO
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Clinton · 2 centers

Compass Health
Clinton, MO
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Compass Health
Clinton, MO
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Florissant · 2 centers

BJC Behavioral Health
Florissant, MO
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Preferred Family Healthcare Inc
Florissant, MO
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Fulton · 2 centers

Compass Health
Fulton, MO
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Harrisonville · 2 centers

Comm Mental Health Consultants Inc
Harrisonville, MO
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Compass Health
Harrisonville, MO
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Jefferson City · 2 centers

Preferred Family Healthcare Inc
Jefferson City, MO
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Compass Health
Jefferson City, MO
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Kirksville · 2 centers

Mark Twain Behavioral Health
Kirksville, MO
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Preferred Family Healthcare Inc
Kirksville, MO
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Marble Hill · 2 centers

Gibson Recovery Center Inc
Marble Hill, MO
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Community Counseling Center
Marble Hill, MO
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Moberly · 2 centers

Mark Twain Behavioral Health
Moberly, MO
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Preferred Family Healthcare Inc
Moberly, MO
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Neosho · 2 centers

Ozark Center/New Directions
Neosho, MO
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Nevada · 2 centers

Compass Health
Nevada, MO
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Comm Mental Health Consultants Inc
Nevada, MO
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Perryville · 2 centers

Community Counseling Center
Perryville, MO
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Gibson Recovery Center Inc
Perryville, MO
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Piedmont · 2 centers

FCC Behavioral Health
Piedmont, MO
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Southeast Missouri Behavioral Health
Piedmont, MO
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Raymore · 2 centers

Compass Health
Raymore, MO
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Compass Health
Raymore, MO
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Saint Charles · 2 centers

Preferred Family Healthcare Inc
Saint Charles, MO
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Preferred Family Healthcare Inc
Saint Charles, MO
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Saint Joseph · 2 centers

Family Guidance Center
Saint Joseph, MO
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St Kolbe Puckett Center for Healing
Saint Joseph, MO
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Salem · 2 centers

Southeast Missouri Behavioral Health
Salem, MO
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Compass Health
Salem, MO
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Sikeston · 2 centers

Bootheel Counseling Services
Sikeston, MO
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Gibson Recovery Center Inc
Sikeston, MO
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Sullivan · 2 centers

Compass Health
Sullivan, MO
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Warrensburg · 2 centers

Compass Health
Warrensburg, MO
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Compass Health
Warrensburg, MO
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Wentzville · 2 centers

Compass Health
Wentzville, MO
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SSM Health Treatment and Recovery
Wentzville, MO
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West Plains · 2 centers

FCC Behavioral Health
West Plains, MO
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FCC Behavioral Health
West Plains, MO
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Ballwin · 1 center
Bowling Green · 1 center

Mark Twain Behavioral Health
Bowling Green, MO
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Branson · 1 center

Communities of Recovery Inc
Branson, MO
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Butler · 1 center

Compass Health
Butler, MO
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Cadet · 1 center

Southeast Missouri Behavioral Health
Cadet, MO
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Cameron · 1 center

Family Guidance Center/Cameron
Cameron, MO
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Canton · 1 center

Preferred Family Healthcare Inc
Canton, MO
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Caruthersville · 1 center

FCC Behavioral Health
Caruthersville, MO
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Cassville · 1 center

Clark Community Mental Health Center
Cassville, MO
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Charleston · 1 center

FCC Behavioral Health
Charleston, MO
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Chillicothe · 1 center

North Central MO Mental Health Center
Chillicothe, MO
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Dittmer · 1 center

Sana Lake Recovery
Dittmer, MO
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Doniphan · 1 center

FCC Behavioral Health
Doniphan, MO
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El Dorado Springs · 1 center

Compass Health
El Dorado Springs, MO
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Eldon · 1 center

Compass Health
Eldon, MO
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Ellington · 1 center

FCC Behavioral Health
Ellington, MO
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Eolia · 1 center

Aviary Recovery Center
Eolia, MO
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Greenfield · 1 center

Clark Community Mental Health Center
Greenfield, MO
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Greenville · 1 center

Family Counseling Center Inc
Greenville, MO
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Hayti · 1 center

Family Counseling Center Inc
Hayti, MO
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Higginsville · 1 center

Compass Health
Higginsville, MO
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Houston · 1 center

Southeast Missouri Behavioral Health
Houston, MO
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Kahoka · 1 center

Preferred Family Healthcare Inc
Kahoka, MO
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Kennett · 1 center

FCC Behavioral Health
Kennett, MO
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Lamar · 1 center

Ozark Center
Lamar, MO
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Lebanon · 1 center
Lees Summit · 1 center

ReDiscover
Lees Summit, MO
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Liberty · 1 center

Heartland Center for Behavioral Change
Liberty, MO
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Linn Creek · 1 center

Compass Health
Linn Creek, MO
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Macon · 1 center

Preferred Family Healthcare Inc
Macon, MO
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Maryland Heights · 1 center

Sana Lake Behavioral Wellness
Maryland Heights, MO
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Maryville · 1 center

Family Guidance Center
Maryville, MO
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Mexico · 1 center

East Central MO Behavioral Health
Mexico, MO
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Monett · 1 center

Clark Community Mental Health Center
Monett, MO
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Montgomery City · 1 center

Arthur Center Community Health
Montgomery City, MO
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Odessa · 1 center

Compass Health
Odessa, MO
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Osage Beach · 1 center

Compass Health
Osage Beach, MO
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Osceola · 1 center

Compass Health
Osceola, MO
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Owensville · 1 center

Compass Health
Owensville, MO
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Ozark · 1 center

Synergy Executive
Ozark, MO
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Richland · 1 center

Central Ozarks Medical Center
Richland, MO
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Richmond · 1 center

Tri County Mental Health Services
Richmond, MO
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Rogersville · 1 center

Synergy Recovery Center
Rogersville, MO
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Rolla · 1 center

Southeast Missouri Behavioral Health
Rolla, MO
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Saint Peters · 1 center

Preferred Family Healthcare Inc
Saint Peters, MO
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Sainte Genevieve · 1 center

Community Counseling Center
Sainte Genevieve, MO
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Sedalia · 1 center

Compass Health Network Inc
Sedalia, MO
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Steelville · 1 center

Southeast Missouri Behavioral Health
Steelville, MO
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Trenton · 1 center

Preferred Family Healthcare Inc
Trenton, MO
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Troy · 1 center

Preferred Family Healthcare Inc
Troy, MO
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Union · 1 center

Preferred Family Healthcare Inc
Union, MO
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Van Buren · 1 center

FCC Behavioral Health
Van Buren, MO
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Warrenton · 1 center

Preferred Family Healthcare
Warrenton, MO
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Warsaw · 1 center

Compass Health
Warsaw, MO
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MO HealthNet
MO HealthNet covers MAT medications and funds MAT induction in jails and emergency departments through state general-fund grants.
State regulations
Missouri Department of Mental Health (DMH) licenses OTPs under 9 CSR 30-3 and funds a Medication First program giving same-day buprenorphine.
- Cash or self-payment152
- Private health insurance146
- Medicaid142
- Federal military insurance (e.g., TRICARE)128
- Medicare117
- Federal, or any government funding for substance use treatment programs109
- Outpatient146
- Regular outpatient treatment144
- Outpatient methadone/buprenorphine or naltrexone treatment118
- Intensive outpatient treatment81
- Outpatient day treatment or partial hospitalization40
Frequently Asked Questions About Naltrexone in Missouri
Do I have to stop using opioids before starting naltrexone?
For methadone and buprenorphine, continued opioid use during induction is common and expected; the medication itself helps stop use. For naltrexone, however, you must complete a 7–14 day opioid-free period first. Your Missouri clinician will tailor the induction based on your medication.
Do I have to pay for counseling separately from the medication?
It depends on the program. Bundled MAT programs include counseling in a single weekly or monthly fee. Others bill counseling separately ($40–$150 per session). MO HealthNet and most commercial plans cover both components when delivered by a licensed provider.
Does MO HealthNet cover long-acting buprenorphine (Sublocade) or naltrexone (Vivitrol)?
Yes. MO HealthNet covers Sublocade and Vivitrol as part of the MAT benefit; most plans require prior authorization documenting prior MAT adherence. Billing is handled by the Missouri provider as a medical (not pharmacy) benefit.
Will my private insurance cover naltrexone treatment in Missouri?
Yes — under the Mental Health Parity and Addiction Equity Act and the Affordable Care Act, marketplace and employer health plans must cover MAT for OUD, including naltrexone. Specific cost-sharing (copay, coinsurance, deductible) depends on your plan tier.
Was the DEA X-waiver requirement for buprenorphine removed in Missouri?
Yes — federal Congress eliminated the X-waiver in December 2022, so any Missouri clinician with a DEA registration can now prescribe buprenorphine for OUD. Continuing-education requirements apply; training is free through Providers Clinical Support System (PCSS) and SAMHSA.
Does length of treatment with naltrexone affect outcomes?
Yes. Meta-analyses consistently find that patients who remain on MAT longer than 12 months have lower rates of relapse, infectious disease, and overdose death. Missouri Medicaid-funded programs report improved retention with long-acting injectables compared to sublingual treatment.
Can I start naltrexone while I’m still using opioids?
For methadone and buprenorphine, continued opioid use at entry is expected — the medication is designed to stop use safely. For naltrexone, 7–14 opioid-free days are required first. Your Missouri clinician will confirm the correct induction strategy at intake.
Will I get medication on the first day of naltrexone?
Usually yes. Missouri programs following low-barrier protocols provide the first buprenorphine dose or naltrexone prescription on day one. Methadone first doses are administered in-clinic and require SAMHSA-certified protocols that are typically completed during the intake visit.
Can naltrexone affect my heart?
Methadone can prolong the QTc interval on ECG; Missouri clinics screen patients with baseline and follow-up ECGs. Buprenorphine and naltrexone do not carry this risk. Patients with cardiac disease can safely use MAT under close cardiology and MAT-team coordination.
Will CPS or DCF automatically be called if I use naltrexone during pregnancy in Missouri?
Missouri has specific protocols: prenatal MAT under medical supervision is typically not grounds for child-welfare action on its own. Hospital social workers may coordinate a Plan of Safe Care as required by CAPTA — this is a supportive plan, not automatic removal.
What happens in naltrexone counseling sessions?
Sessions cover craving management, relapse-prevention skills, coping strategies, relationship issues, trauma processing if relevant, and goal setting for recovery. The counselor and client collaborate on a written treatment plan that is updated every 30–90 days in Missouri.
Are group-counseling sessions confidential?
Yes. Group members sign confidentiality agreements, and the clinician protects group content under 42 CFR Part 2. Enforcement between group members depends on honor among peers, but legal protections limit disclosure by the clinic or clinician.
Other Treatment Options in Missouri
Naltrexone Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)



