Medication-Assisted Treatment (MAT) Centers in Illinois
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 507 MAT programs across Illinois, with the largest concentrations in Chicago (94), Joliet (9) and Springfield (6).
Medication-Assisted Treatment (MAT) combines FDA-approved medications — methadone, buprenorphine, and naltrexone — with counseling and behavioral therapies for comprehensive addiction care. MAT is the evidence-based gold standard for opioid and alcohol use disorders.
Treatment landscape in Illinois:
- Comprehensive treatment options in Chicago metro
- Illinois Medicaid covers substance abuse services
- Diverse specializations including LGBTQ+ focused care
- Strong academic medical center partnerships
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MAT programs in Illinois
Chicago · 94 centers

A Safe Haven
Chicago, IL
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Access Booker Family Health Ctr
Chicago, IL
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Access Grand Boulevard Family Health
Chicago, IL
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Esperanza
Chicago, IL
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Esperanza
Chicago, IL
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Gateway Foundation
Chicago, IL
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Gateway Foundation
Chicago, IL
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Harbor Light Alcoholism and Drug
Chicago, IL
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Henrys Sober Living House
Chicago, IL
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Jesse Brown Addiction Programs
Chicago, IL
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KAM Alliance Inc
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Loretto Hospital
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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Near North Health
Chicago, IL
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Positive Sobriety Institute
Chicago, IL
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Prentice Place
Chicago, IL
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Saint Annes Home
Chicago, IL
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SunCloud Health SC
Chicago, IL
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Symetria Recovery
Chicago, IL
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Trilogy Inc
Chicago, IL
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Thresholds
Chicago, IL
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Allens Family Counseling Center Inc
Chicago, IL
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A Beautiful Mind Inc
Chicago, IL
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Access Austin Family Health Ctr
Chicago, IL
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Esperanza
Chicago, IL
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Access Westside Family Health
Chicago, IL
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Center for Addictive Problems
Chicago, IL
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Friend Health
Chicago, IL
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Access Madison Family Health Ctr
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Human Resources Development Inst
Chicago, IL
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LSSI
Chicago, IL
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Near North Health Service Corporation
Chicago, IL
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Olatoye Rehabilitation Center Inc
Chicago, IL
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Access Brandon Family Health Ctr
Chicago, IL
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Access Evanston Rogers Park Family Ctr
Chicago, IL
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Healthcare Alternative Systems Inc
Chicago, IL
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Healthcare Alternative Systems Inc
Chicago, IL
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HRDI
Chicago, IL
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Human Resources Development Inst
Chicago, IL
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Kirby Rehabilitation
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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McDermott Center/Haymarket Ctr
Chicago, IL
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New Age Services Corporation
Chicago, IL
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New Hope Community Service Center
Chicago, IL
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Prentice Place
Chicago, IL
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ABRAXAS Youth and Family Services
Chicago, IL
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Access Ashland Family Health Ctr
Chicago, IL
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Access Humbolt Park Family Health Ctr
Chicago, IL
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Ann and Robert H Lurie Childs Hosp of
Chicago, IL
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Chicago Pride Center
Chicago, IL
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Family Guidance Centers Inc
Chicago, IL
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Friend Family Health Center
Chicago, IL
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Friend Family Health Center
Chicago, IL
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Friend Family Health Center
Chicago, IL
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Friend Family Health Center
Chicago, IL
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Healthcare Alternative Systems Inc
Chicago, IL
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HRDI/Harriet Tubman Womens
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Lawndale Christian Health Center
Chicago, IL
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Loren Half Robinson Foundation
Chicago, IL
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Thresholds
Chicago, IL
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Joliet · 9 centers

Family Guidance Centers Inc
Joliet, IL
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Cornerstone Services Inc
Joliet, IL
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Stepping Stones Inc
Joliet, IL
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Symetria Recovery
Joliet, IL
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Stepping Stones Inc
Joliet, IL
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Stepping Stones Inc
Joliet, IL
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Stepping Stones Inc
Joliet, IL
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Stepping Stones Inc
Joliet, IL
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Peoria · 6 centers

New Leaf
Peoria, IL
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IL Institute for Addiction Recovery
Peoria, IL
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Trillium Place
Peoria, IL
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Rose Medical Association Inc/Peoria
Peoria, IL
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Trillium Place
Peoria, IL
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Springfield · 6 centers

Riverwood Group LLC
Springfield, IL
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Family Guidance Centers Inc
Springfield, IL
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Rose Medical Association Inc
Springfield, IL
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Rockford · 5 centers

Crusader Community Health
Rockford, IL
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Rosecrance Inc
Rockford, IL
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Rosecrance Inc
Rockford, IL
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Remedies Renewing Lives
Rockford, IL
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Carbondale · 4 centers

Gateway Foundation
Carbondale, IL
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Shawnee Healthcare
Carbondale, IL
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Centerstone of Illinois
Carbondale, IL
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Shawnee Healthcare
Carbondale, IL
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Chicago Heights · 4 centers

Serenity Trt and Counseling Ctr Inc
Chicago Heights, IL
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Access Family Health Society
Chicago Heights, IL
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Grand Prairie Services
Chicago Heights, IL
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Elgin · 4 centers

Ecker Center for Behavioral Health
Elgin, IL
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Footprints Recovery IL
Elgin, IL
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Greater Family Health
Elgin, IL
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Mathers Recovery LLC
Elgin, IL
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Naperville · 4 centers

SunCloud Health SC
Naperville, IL
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Naperville Psychiatric Ventures
Naperville, IL
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Naperville Psychiatric Ventures
Naperville, IL
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Palos Heights · 4 centers

Northwestern Medicine Palos Hospital
Palos Heights, IL
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Symetria Recovery
Palos Heights, IL
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Ascension Illinois Presence Behavioral
Palos Heights, IL
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Radius Foundation Inc
Palos Heights, IL
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Belleville · 3 centers

Gateway Foundation
Belleville, IL
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Illinois Recovery Center LLC
Belleville, IL
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Chestnut Health Systems Inc
Belleville, IL
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Champaign · 3 centers

Recovery Concepts Urbana LLC
Champaign, IL
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Rosecrance Inc
Champaign, IL
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Carle Addiction Recovery Center
Champaign, IL
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Decatur · 3 centers

Heritage Behavioral Health Center
Decatur, IL
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Crossing Recovery Center
Decatur, IL
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Elements at Crossing Healthcare
Decatur, IL
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Des Plaines · 3 centers

Access Genesis Center for Health and
Des Plaines, IL
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Symetria Recovery
Des Plaines, IL
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Family Guidance Centers Inc
Des Plaines, IL
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Gurnee · 3 centers

Gateway Foundation
Gurnee, IL
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Behavioral Services Center
Gurnee, IL
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Waukegan · 3 centers

Lake County Substance Abuse Prog
Waukegan, IL
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Anna · 2 centers

Rural Health Inc
Anna, IL
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Arlington Heights · 2 centers

Access Northwest Family Health Center
Arlington Heights, IL
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A Bridge Back Inc
Arlington Heights, IL
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Aurora · 2 centers

Gateway Foundation
Aurora, IL
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Family Guidance Centers Inc
Aurora, IL
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Blue Island · 2 centers

Access Blue Island Family Health Ctr
Blue Island, IL
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ACCESS Blue Island Medical Center
Blue Island, IL
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Calumet City · 2 centers

Great Heights OTP
Calumet City, IL
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Christian Community Health Center
Calumet City, IL
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Carlinville · 2 centers

Acorn Counseling and Mediation Ltd
Carlinville, IL
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Macoupin County Public Health Dept
Carlinville, IL
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Carterville · 2 centers

Centerstone of Illinois
Carterville, IL
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Shawnee Healthcare
Carterville, IL
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Carthage · 2 centers

Memorial Medical Clinic
Carthage, IL
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Memorial Medical Clinic
Carthage, IL
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Dixon · 2 centers

Sinnissippi Centers Inc
Dixon, IL
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Sinnissippi Centers Inc
Dixon, IL
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East Saint Louis · 2 centers

Comprehensive Behavior Health Center
East Saint Louis, IL
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Touchette Regional Hospital
East Saint Louis, IL
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Evanston · 2 centers

Bobby Buonauro Clinic Inc
Evanston, IL
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Geneva · 2 centers
Hazel Crest · 2 centers

South Suburban Council on
Hazel Crest, IL
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Kankakee · 2 centers

Duane Dean Behavioral Health Center
Kankakee, IL
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Iroquois Mental Health Center
Kankakee, IL
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Manteno · 2 centers

Family Guidance Centers Inc
Manteno, IL
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Iroquois Mental Health Center
Manteno, IL
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Marion · 2 centers

Shawnee Healthcare
Marion, IL
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Centerstone of Illinois
Marion, IL
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Monmouth · 2 centers

Henderson County Rural Health Center
Monmouth, IL
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Bridgeway Inc
Monmouth, IL
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Oak Lawn · 2 centers
Ottawa · 2 centers

Great Heights OTP
Ottawa, IL
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Saint Charles · 2 centers

Recovery Centers of America
Saint Charles, IL
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Lighthouse Recovery Inc
Saint Charles, IL
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Schaumburg · 2 centers

Alexian Brothers BH Hosp
Schaumburg, IL
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Behavioral Healthcare Providers Ltd
Schaumburg, IL
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South Holland · 2 centers

Christian Community Health Center
South Holland, IL
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Vernon Hills · 2 centers

Symetria Recovery
Vernon Hills, IL
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Lake County Health Dept/CHC
Vernon Hills, IL
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Wheaton · 2 centers

Stonybrook Center Inc
Wheaton, IL
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Healthcare Alternative Systems Inc
Wheaton, IL
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Addison · 1 center

DuPage County Health Department
Addison, IL
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Alton · 1 center

Centerstone of Illinois
Alton, IL
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Amboy · 1 center

Sinnissippi Centers Inc
Amboy, IL
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Beardstown · 1 center

Cass County Health Department
Beardstown, IL
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Belvidere · 1 center
Benton · 1 center

Rea Clinic Benton
Benton, IL
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Berwyn · 1 center

MacNeal Hospital
Berwyn, IL
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Bloomingdale · 1 center

ACCESS Martin T Russo Family Hlth Ctr
Bloomingdale, IL
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Bloomington · 1 center

Chestnut Health Systems Inc
Bloomington, IL
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Bolingbrook · 1 center

New Day Place LLC
Bolingbrook, IL
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Bourbonnais · 1 center
Broadview · 1 center

Healthcare Alternative Systems Inc
Broadview, IL
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Buffalo Grove · 1 center

Sandstone Care
Buffalo Grove, IL
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Carlyle · 1 center

Community Resource Center
Carlyle, IL
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Caseyville · 1 center

Gateway Foundation
Caseyville, IL
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Chester · 1 center

ComWell
Chester, IL
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Colchester · 1 center

Memorial Medical Clinic
Colchester, IL
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Danville · 1 center

VA Illiana Healthcare System
Danville, IL
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Darien · 1 center

Sandstone Care
Darien, IL
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Dongola · 1 center

Rural Health Inc
Dongola, IL
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Downers Grove · 1 center

CAP of Downers Grove
Downers Grove, IL
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Du Quoin · 1 center

CRHPC Comprehensive Behav Health Ctr
Du Quoin, IL
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East Peoria · 1 center
Edwardsville · 1 center

Addiction Treatment Strategies
Edwardsville, IL
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Elk Grove Village · 1 center

Alexian Brothers/Foglia Family
Elk Grove Village, IL
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Elmhurst · 1 center

New Age Services Corporation
Elmhurst, IL
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Evergreen Park · 1 center

OSF Little Company of Mary Medical Ctr
Evergreen Park, IL
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Flora · 1 center

Clay Medical Center
Flora, IL
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Fox Lake · 1 center

Mathers Recovery LLC
Fox Lake, IL
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Freeport · 1 center

Sinnissippi Centers Inc
Freeport, IL
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Galesburg · 1 center

Bridgeway Inc
Galesburg, IL
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Gillespie · 1 center

Macoupin County Public Health Departme
Gillespie, IL
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Goreville · 1 center

Rural Health Inc
Goreville, IL
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Granite City · 1 center

Chestnut Health Systems Inc
Granite City, IL
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Greenville · 1 center

Bond County Health Department
Greenville, IL
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Hamilton · 1 center

Memorial Medical Clinic
Hamilton, IL
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Hanover Park · 1 center

Greater Family Health
Hanover Park, IL
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Harrisburg · 1 center

Egyptian Public and Mental Health Dept
Harrisburg, IL
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Harvey · 1 center

Family Guidance Centers Inc
Harvey, IL
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Hines · 1 center

Vet Affairs/Edward Hines Jr Hospital
Hines, IL
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Hoffman Estates · 1 center
Jacksonville · 1 center

Gateway Foundation
Jacksonville, IL
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Kewanee · 1 center

Bridgeway Inc
Kewanee, IL
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La Salle · 1 center

Local NP PC
La Salle, IL
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Lake Villa · 1 center

Gateway Foundation
Lake Villa, IL
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Lawrenceville · 1 center

Lawrence County Health Department
Lawrenceville, IL
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Lemont · 1 center

Timberline Knolls
Lemont, IL
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Lisle · 1 center

Lott Behavioral Health
Lisle, IL
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Litchfield · 1 center

Macoupin County Public Health Dept
Litchfield, IL
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Maryville · 1 center

CenterPointe Maryville
Maryville, IL
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Maywood · 1 center

Substance Abuse Operations
Maywood, IL
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Melrose Park · 1 center

Healthcare Alternative Systems Inc
Melrose Park, IL
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Metropolis · 1 center

Rural Health Inc
Metropolis, IL
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Milan · 1 center

Top of the World Ranch
Milan, IL
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Morris · 1 center

Grundy County Health Department
Morris, IL
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Mount Carroll · 1 center

Sinnissippi Centers Inc
Mount Carroll, IL
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Mount Vernon · 1 center

Comprehensive Connections
Mount Vernon, IL
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Murphysboro · 1 center

Shawnee Healthcare
Murphysboro, IL
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Nauvoo · 1 center

Memorial Medical Clinic
Nauvoo, IL
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Normal · 1 center

Carle BroMenn Medical Center
Normal, IL
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North Chicago · 1 center

Captain James A Lovell FHCC
North Chicago, IL
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Northbrook · 1 center

SunCloud Health SC
Northbrook, IL
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Okawville · 1 center

ComWell
Okawville, IL
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Oregon · 1 center

Sinnissippi Centers Inc
Oregon, IL
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Orland Park · 1 center

Northwestern Medicine
Orland Park, IL
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Pittsfield · 1 center

Clarity Healthcare
Pittsfield, IL
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Plainfield · 1 center

Naperville Psychiatric Ventures
Plainfield, IL
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Pontiac · 1 center

Institute for Human Resources
Pontiac, IL
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Quincy · 1 center
Raymond · 1 center

Lincoln Recovery
Raymond, IL
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Red Bud · 1 center

ComWell
Red Bud, IL
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Rochelle · 1 center

Sinnissippi Centers Inc
Rochelle, IL
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Rock Island · 1 center

Center for Alc and Drug Services Inc
Rock Island, IL
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Rolling Meadows · 1 center

Therapeutic Interventions Inc
Rolling Meadows, IL
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Sesser · 1 center

Sesser Community Health Center
Sesser, IL
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Skokie · 1 center

Behavior Services Center
Skokie, IL
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South Elgin · 1 center

Recovery Centers of America
South Elgin, IL
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Sparta · 1 center

ComWell
Sparta, IL
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Sterling · 1 center

Sinnissippi Centers Inc
Sterling, IL
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Stone Park · 1 center
Stronghurst · 1 center

Henderson County Rural Health Center
Stronghurst, IL
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Sycamore · 1 center

Greater Family Health
Sycamore, IL
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Vienna · 1 center

Rural Health Inc
Vienna, IL
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Warrenville · 1 center

Symetria Recovery
Warrenville, IL
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Washington · 1 center
Waterloo · 1 center

Human Support Services
Waterloo, IL
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Watseka · 1 center

Iroquois Mental Health Center
Watseka, IL
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West Chicago · 1 center

Access West Chicago Family Health Ctr
West Chicago, IL
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West Frankfort · 1 center

Centerstone of Illinois
West Frankfort, IL
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Westchester · 1 center

Ascension Illinois Presence Behavioral
Westchester, IL
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Westmont · 1 center

Adventist Hinsdale Hospital
Westmont, IL
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Wheeling · 1 center

Greater Family Health
Wheeling, IL
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Woodstock · 1 center

Thresholds
Woodstock, IL
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Yorkville · 1 center

Kendall County Health Department
Yorkville, IL
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Showing 300 of 507 MAT programs in Illinois. Browse all centers in Illinois
Illinois Medicaid (HFS)
Illinois Medicaid covers methadone, buprenorphine, and naltrexone; the state pays for long-acting injectable buprenorphine (Sublocade) without step therapy.
State regulations
Illinois Division of Substance Use Prevention and Recovery (SUPR) licenses OTPs and funds a 24/7 warm-handoff line for MAT referrals.
- Cash or self-payment287
- Private health insurance244
- Medicaid242
- Medicare189
- State-financed health insurance plan other than Medicaid180
- Federal, or any government funding for substance use treatment programs171
- Outpatient273
- Regular outpatient treatment256
- Outpatient methadone/buprenorphine or naltrexone treatment214
- Intensive outpatient treatment154
- Residential/24-hour residential58
Frequently Asked Questions About MAT in Illinois
Do I need a formal OUD diagnosis before starting mat?
Yes. Providers in Illinois must document a current OUD diagnosis to prescribe mat as part of medication-assisted treatment. The intake assessment typically takes 60–90 minutes and includes a physical exam, drug screen, and psychiatric history — results are used to confirm eligibility.
Can I get free mat treatment in Illinois?
Free mat treatment is possible in Illinois for patients who qualify for Illinois Medicaid (HFS), are enrolled in State Opioid Response–funded clinics, or use charity-care programs at community behavioral-health centers. Call 988 or 1-800-662-4357 for live referrals.
Do I need prior authorization for mat under Illinois Medicaid (HFS)?
Most Illinois Medicaid (HFS) plans have eliminated prior authorization for MAT medications, but long-acting injectables like Sublocade and Vivitrol may still require PA. Your Illinois provider’s billing staff will handle any authorizations needed before your first dose.
Does Medicare cover mat in Illinois?
Yes. Medicare Part B covers methadone through enrolled Opioid Treatment Programs and Part D covers buprenorphine and naltrexone prescriptions. Medicare Advantage plans in Illinois include the same MAT benefits under the integrated plan structure.
What documentation does a Illinois mat clinic keep about me?
Clinics maintain a confidential medical record covering diagnosis, treatment plan, drug screens, counseling notes, and dose history. Records are protected by 42 CFR Part 2 — stricter than HIPAA — and cannot be released without your written consent or a specific court order.
How long does mat treatment typically last in Illinois?
Many Illinois patients stay on mat for a year or more, and some stay indefinitely. Duration depends on individual stability, quality of life, and risk of relapse. Research consistently shows that longer MAT duration is associated with lower overdose mortality.
Can I start mat the same day I call?
Same-day induction is increasingly common in Illinois — especially for buprenorphine at low-barrier clinics and in emergency departments. Methadone same-day starts depend on OTP capacity; call early in the day to maximize your chance of same-day intake.
Can I drive myself home from the first mat dose in Illinois?
Illinois programs generally recommend arranging a ride for the first induction visit, since initial drowsiness is common. After the first 1–2 weeks at a stable dose, patients typically resume driving and most daily activities without restriction.
Will mat show on a standard drug test?
Buprenorphine and methadone do not test positive on standard 5-panel drug tests — specialty panels are needed. Naltrexone and its metabolites are not screened on standard panels. Share an MAT provider letter with any employer or court drug-testing program to avoid confusion.
Is mat safe during pregnancy in Illinois?
Yes. Methadone and buprenorphine are the evidence-based standard of care in pregnancy, endorsed by ACOG and SAMHSA. Staying on MAT protects both mother and fetus; unmedicated withdrawal is riskier than continued MAT. Illinois providers coordinate care with obstetrics.
Does Illinois Medicaid (HFS) cover counseling along with mat?
Yes. Illinois Medicaid (HFS) covers individual therapy, group sessions, and care coordination at Illinois MAT clinics without separate deductibles in most plans. Peer-recovery support services are also covered in Illinois.
Can I keep my mat treatment private from my health-insurance company?
If you use insurance, the insurer sees billed services (including MAT). They cannot share that with your employer or family. If you strongly value privacy from insurance, self-pay is the only fully insulated option.
Other Treatment Options in Illinois
Medication-Assisted Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)






















