Medication-Assisted Treatment (MAT) Centers in Pennsylvania
Medically reviewed by Sarah Mitchell, LCSWLast reviewed: April 2026
Our directory lists 367 MAT programs across Pennsylvania, with the largest concentrations in Philadelphia (38), Pittsburgh (18) and Erie (9).
Medication-Assisted Treatment (MAT) combines FDA-approved medications — methadone, buprenorphine, and naltrexone — with counseling and behavioral therapies for comprehensive addiction care. MAT is the evidence-based gold standard for opioid and alcohol use disorders.
Treatment landscape in Pennsylvania:
- PA Medical Assistance covers addiction treatment
- Major treatment hubs in Philadelphia and Pittsburgh
- Strong network of Centers of Excellence
- Extensive rural and urban coverage
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MAT programs in Pennsylvania
Philadelphia · 38 centers

Asociacion Puertorriquenos en Marcha
Philadelphia, PA
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Healing Way
Philadelphia, PA
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John F Kennedy Behavioral Health
Philadelphia, PA
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Kensington Hospital
Philadelphia, PA
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Kirkbride Center
Philadelphia, PA
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Mazzoni Center
Philadelphia, PA
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Northeast Treatment Centers
Philadelphia, PA
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Providence Treatment
Philadelphia, PA
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Limitless Recovery LLC
Philadelphia, PA
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Interim House Inc
Philadelphia, PA
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High Focus Centers
Philadelphia, PA
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Gaudenzia DRC Inc
Philadelphia, PA
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Greater Philadelphia Asian Social Serv
Philadelphia, PA
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Asociacion Puertorriquenos en Marcha
Philadelphia, PA
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Gaudenzia Inc
Philadelphia, PA
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Malvern Treatment Centers
Philadelphia, PA
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Merakey Parkside Recovery
Philadelphia, PA
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Merakey Parkside Recovery
Philadelphia, PA
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Casa de Consejeria y Salud Integral
Philadelphia, PA
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Casa de Consejeria y Salud Integral
Philadelphia, PA
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Family Center of Thomas Jefferson Univ
Philadelphia, PA
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Gaudenzia
Philadelphia, PA
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Interim House West Inc
Philadelphia, PA
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John F Kennedy Behavioral Health
Philadelphia, PA
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North Philadelphia Health Systems
Philadelphia, PA
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North Philadelphia Health Systems
Philadelphia, PA
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Northeast Treatment Centers
Philadelphia, PA
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Pittsburgh · 18 centers

Jade Wellness Center
Pittsburgh, PA
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Pittsburgh Comprehensive Treatment Ctr
Pittsburgh, PA
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POWER House
Pittsburgh, PA
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Pyramid Healthcare Inc
Pittsburgh, PA
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Allied Addiction Recovery LLC
Pittsburgh, PA
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Outpatient Addiction Recovery Services
Pittsburgh, PA
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Progressive Medical Specialists Inc
Pittsburgh, PA
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Allied Addiction Recovery LLC
Pittsburgh, PA
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Pittsburgh Mercy
Pittsburgh, PA
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Erie · 9 centers

Mill Creek Community Hospital
Erie, PA
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Pyramid Healthcare Inc
Erie, PA
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Gaudenzia Inc
Erie, PA
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Gaudenzia Inc
Erie, PA
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Gaudenzia Inc
Erie, PA
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Gage House
Erie, PA
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Lancaster · 8 centers

Blueprints For Addiction Recovery Inc
Lancaster, PA
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Ponessa Behavioral Health
Lancaster, PA
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Gate House Behavioral Health Services
Lancaster, PA
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Nuestra Clinica
Lancaster, PA
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Altoona · 7 centers

Phoenix Domus LLC
Altoona, PA
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Pyramid Healthcare Inc
Altoona, PA
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Pyramid Healthcare Inc
Altoona, PA
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James E Van Zandt VA Medical Center
Altoona, PA
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Butler · 6 centers

Butler Regional Recovery Program
Butler, PA
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Butler Regional Recovery Program
Butler, PA
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Care Center
Butler, PA
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Harrisburg · 5 centers

Harrisburg Comprehensive Treatment Ctr
Harrisburg, PA
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Ponessa Behavioral Health
Harrisburg, PA
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Pennsylvania Psychiatric Institute
Harrisburg, PA
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Evergreen House of Catholic Charities
Harrisburg, PA
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Langhorne · 5 centers

Banyan Philadelphia
Langhorne, PA
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Family Service Assoc of Bucks County
Langhorne, PA
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Penndel Mental Health Center
Langhorne, PA
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Norristown · 5 centers

Avenues Recovery Center at
Norristown, PA
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Eagleville Hospital
Norristown, PA
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Central Behavioral Health
Norristown, PA
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Reading · 5 centers

Berks Counseling Center
Reading, PA
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New Directions Treatment Services
Reading, PA
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Washington · 5 centers

Allied Addiction Recovery LLC
Washington, PA
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CARE Center Inc
Washington, PA
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Greenbriar Treatment Center
Washington, PA
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Greenbriar Treatment Center
Washington, PA
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Bethlehem · 4 centers

Lehigh County Center for Recovery
Bethlehem, PA
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Greensburg · 4 centers

Allied Addiction Recovery LLC
Greensburg, PA
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Clear Day Treatment of Westmoreland
Greensburg, PA
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Williamsport · 4 centers

Crossroads Counseling Inc
Williamsport, PA
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Clearfield · 3 centers

Community Guidance Center
Clearfield, PA
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Cen Clear Child Services Inc
Clearfield, PA
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Hazleton · 3 centers

ClearVision Health and Wellness LLC
Hazleton, PA
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Pathway to Recovery
Hazleton, PA
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Lake Ariel · 3 centers

Avenues Recovery Center at Lake Ariel
Lake Ariel, PA
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Lebanon · 3 centers

Lebanon Comprehensive Treatment Center
Lebanon, PA
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Ponessa Behavioral Health
Lebanon, PA
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Mechanicsburg · 3 centers

Arkview Recovery Center
Mechanicsburg, PA
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Mechanicsburg Comprehensive Trt Ctr
Mechanicsburg, PA
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Diakon Family Life Services
Mechanicsburg, PA
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Pottsville · 3 centers

Clinical Outcomes Group Inc
Pottsville, PA
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Scranton · 3 centers

Dunmore Comprehensive Treatment Center
Scranton, PA
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Wexford · 3 centers
Wilkes Barre · 3 centers
York · 3 centers

Ponessa Behavioral Health
York, PA
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Aliquippa · 2 centers

Outpatient Addiction Recovery Services
Aliquippa, PA
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Bensalem · 2 centers

Livengrin Foundation Inc
Bensalem, PA
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Libertae Inc
Bensalem, PA
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Bloomsburg · 2 centers

Crossroads Counseling
Bloomsburg, PA
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Bridgeville · 2 centers

Chartiers Community MH and Retardatio
Bridgeville, PA
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Colmar · 2 centers

Montco Recovery Center
Colmar, PA
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Penn Foundation
Colmar, PA
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Devon · 2 centers

Recovery Centers of America
Devon, PA
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Recovery Centers of America
Devon, PA
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Doylestown · 2 centers

Aldie Counseling Center
Doylestown, PA
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Duncansville · 2 centers

Duncansville Comprehensive Trt Ctr
Duncansville, PA
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Pyramid Healthcare Inc
Duncansville, PA
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Elizabethtown · 2 centers
Ephrata · 2 centers

NR Pennsylvania Associates LLC
Ephrata, PA
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Exton · 2 centers

MPower Wellness of Pennsylvania LLC
Exton, PA
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Mirmont Outpatient Center
Exton, PA
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Farrell · 2 centers

Farrell Comprehensive Treatment Center
Farrell, PA
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Resolutions Recovery Center
Farrell, PA
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Homestead · 2 centers

Passages to Recovery
Homestead, PA
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Resources for Human Development
Homestead, PA
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Huntingdon · 2 centers

Cen Clear Child Services Inc
Huntingdon, PA
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Johnstown · 2 centers
King of Prussia · 2 centers

North Star Treatment Services
King of Prussia, PA
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Malvern · 2 centers

Recovery Centers of America
Malvern, PA
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Malvern Treatment Center
Malvern, PA
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Media · 2 centers

Providence Treatment
Media, PA
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Mirmont Treatment Center
Media, PA
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Monroeville · 2 centers

Jade Wellness Center
Monroeville, PA
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Recovery Centers of America
Monroeville, PA
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Morrisville · 2 centers

Kolmac Integrated Behavioral Health
Morrisville, PA
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Good Friends Inc
Morrisville, PA
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Phoenixville · 2 centers

Pennsylvania Recovery Center
Phoenixville, PA
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Holcomb Associates
Phoenixville, PA
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Pottstown · 2 centers

Pottstown Comprehensive Treatment Ctr
Pottstown, PA
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Alternative Counseling Associates
Pottstown, PA
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Sharon · 2 centers

Gaudenzia Inc
Sharon, PA
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Sunbury · 2 centers

Crossroads Counseling Inc
Sunbury, PA
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Uniontown · 2 centers

Angels Light Addiction Specialists
Uniontown, PA
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Fayette Cnty Drug/Alc Commission Inc
Uniontown, PA
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Waynesburg · 2 centers

CARE Center Inc
Waynesburg, PA
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Abbottstown · 1 center
Allentown · 1 center

PursueCare
Allentown, PA
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Ambridge · 1 center
Ardmore · 1 center

Resources for Human Development
Ardmore, PA
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Bangor · 1 center

Recovery Revolution Inc
Bangor, PA
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Bartonsville · 1 center
Beavertown · 1 center

Conewago Snyder
Beavertown, PA
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Belleville · 1 center
Berwick · 1 center
Bradford · 1 center

Guidance Center
Bradford, PA
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Bristol · 1 center

Gaudenzia Inc
Bristol, PA
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Brookhaven · 1 center
Brookville · 1 center
Broomall · 1 center

Mirmont Outpatient Center
Broomall, PA
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Bryn Mawr · 1 center

Lower Merion Counseling and
Bryn Mawr, PA
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Carmichaels · 1 center

Fayette Treatment Program LLC
Carmichaels, PA
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Charleroi · 1 center
Clarion · 1 center
Coal Township · 1 center

Merakey Behavioral Health
Coal Township, PA
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Coalport · 1 center

Cen Clear Child Services Inc
Coalport, PA
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Coatesville · 1 center

Coatesville Comprehensive Trt Center
Coatesville, PA
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Corry · 1 center
Cranberry Township · 1 center

Cranberry Township Comp Trt Center
Cranberry Township, PA
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Donegal · 1 center

DreamLife Recovery LLC
Donegal, PA
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Dresher · 1 center

Gaudenzia
Dresher, PA
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Du Bois · 1 center

Community Guidance Center
Du Bois, PA
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Easton · 1 center

Recovery Cove
Easton, PA
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Ebensburg · 1 center
Elizabethville · 1 center
Ellwood City · 1 center
Factoryville · 1 center

Endless Mountains Extended Care LLC
Factoryville, PA
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Fairless Hills · 1 center
Farmington · 1 center
Fort Washington · 1 center
Hanover · 1 center

BriteLife Recovery at Hanover
Hanover, PA
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Havertown · 1 center

American Treatment Network
Havertown, PA
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Henryville · 1 center

Pocono Mountain Recovery Center
Henryville, PA
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Hollidaysburg · 1 center

Impact Counseling Services LLC
Hollidaysburg, PA
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Houston · 1 center
Hummelstown · 1 center
Huntingdon Valley · 1 center

Huntingdon Valley Comp Trt Center
Huntingdon Valley, PA
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Indiana · 1 center

Open Door of Indiana Pennsylvania
Indiana, PA
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Jamestown · 1 center
Jamison · 1 center

Avenues Recovery Center at Bucks
Jamison, PA
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Jenkintown · 1 center

Rehab After Work
Jenkintown, PA
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Kennett Square · 1 center

Holcomb Associates Inc
Kennett Square, PA
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Kittanning · 1 center

Armstrong County Council on Alc and
Kittanning, PA
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Lansdale · 1 center

Retreat at Lancaster County PA LLC
Lansdale, PA
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Lemont Furnace · 1 center
Lemoyne · 1 center
Lewisburg · 1 center
Linesville · 1 center
Lititz · 1 center

GateHouse
Lititz, PA
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Lock Haven · 1 center

Crossroads Counseling Inc
Lock Haven, PA
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Mansfield · 1 center
Marietta · 1 center

GateHouse
Marietta, PA
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McKeesport · 1 center

Mon Yough Community Services
McKeesport, PA
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Middleburg · 1 center
Millerton · 1 center

Bradford Recovery Center
Millerton, PA
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Mount Joy · 1 center

Blueprints for Addiction Recovery Inc
Mount Joy, PA
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Mount Pleasant · 1 center
Mount Pocono · 1 center
Mountville · 1 center

GateHouse
Mountville, PA
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New Castle · 1 center

New Castle Comprehensive Treatment Ctr
New Castle, PA
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New Kensington · 1 center
Newtown · 1 center

Avise Wellness Collective
Newtown, PA
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Northern Cambria · 1 center

Community Guidance Center
Northern Cambria, PA
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Orefield · 1 center

Allentown Comprehensive Treatment Ctr
Orefield, PA
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Paradise · 1 center
Perryopolis · 1 center
Philipsburg · 1 center

Cen Clear Child Services Inc
Philipsburg, PA
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Plymouth Meeting · 1 center
Polk · 1 center

Oil Region Recovery
Polk, PA
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Punxsutawney · 1 center

Cen Clear Child Services Inc
Punxsutawney, PA
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Rehrersburg · 1 center

Ascend Clinical Services
Rehrersburg, PA
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Roaring Spring · 1 center

Cen Clear Child Services Inc
Roaring Spring, PA
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Rochester · 1 center
Saint Clair · 1 center
Saint Marys · 1 center

Cen Clear Child Services Inc
Saint Marys, PA
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Scotrun · 1 center

Brookdale Premier Addiction Recovery
Scotrun, PA
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Sharon Hill · 1 center

Merakey
Sharon Hill, PA
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Shickshinny · 1 center

Huntington Creek Recovery Center
Shickshinny, PA
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Sidman · 1 center

Allegiance Rehabilitation Center
Sidman, PA
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Somerset · 1 center

Beal Counseling and Consulting
Somerset, PA
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Southampton · 1 center
State College · 1 center

Crossroads Counseling Inc
State College, PA
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Tionesta · 1 center

Deerfield Centers for Addictions Trt
Tionesta, PA
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Upper Darby · 1 center

Harwood House
Upper Darby, PA
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Warren · 1 center
Waynesboro · 1 center

Pyramid Healthcare Inc
Waynesboro, PA
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Wellsboro · 1 center

Crossroads Counseling Inc
Wellsboro, PA
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Wernersville · 1 center

Caron Treatment Centers
Wernersville, PA
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West Chester · 1 center

Gaudenzia Inc
West Chester, PA
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Willow Grove · 1 center

Malvern Treatment Centers
Willow Grove, PA
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Yeagertown · 1 center

Cen Clear Child Services Inc
Yeagertown, PA
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Showing 300 of 367 MAT programs in Pennsylvania. Browse all centers in Pennsylvania
Pennsylvania Medical Assistance (PA MA)
PA Medical Assistance covers methadone, buprenorphine, and naltrexone without prior authorization; the state funds Centers of Excellence for MAT coordination.
State regulations
Pennsylvania Department of Drug and Alcohol Programs (DDAP) licenses Narcotic Treatment Programs; the state operates 45+ COEs that coordinate MAT placement.
- Cash or self-payment287
- Medicaid264
- Private health insurance249
- State-financed health insurance plan other than Medicaid163
- Federal, or any government funding for substance use treatment programs161
- Medicare117
- Outpatient234
- Regular outpatient treatment211
- Outpatient methadone/buprenorphine or naltrexone treatment190
- Intensive outpatient treatment153
- Residential/24-hour residential84
Frequently Asked Questions About MAT in Pennsylvania
Do I have to stop using opioids before starting mat?
For methadone and buprenorphine, continued opioid use during induction is common and expected; the medication itself helps stop use. For naltrexone, however, you must complete a 7–14 day opioid-free period first. Your Pennsylvania clinician will tailor the induction based on your medication.
Is the first visit to a mat provider free?
Some Pennsylvania programs offer a free screening or phone intake; others charge an initial assessment fee ($100–$300 self-pay). Federally qualified health centers often waive the first visit. Ask up front about assessment fees when you schedule your appointment.
Does Pennsylvania Medical Assistance (PA MA) cover a full month’s supply of mat?
Yes. For methadone, Pennsylvania Medical Assistance (PA MA) reimburses Opioid Treatment Programs (OTPs) for in-clinic and take-home dosing as a bundled rate — SAMHSA clinical rules, not insurance, govern take-home eligibility. For buprenorphine, Pennsylvania Medical Assistance (PA MA) pays for the 30-day pharmacy fill. For long-acting naltrexone, the monthly injection is covered under the medical benefit.
Do employer-provided high-deductible plans cover mat?
Yes — federal parity rules require employer plans to cover MAT. High-deductible plans charge patient-paid rates until the deductible is met; HSA funds can be used for MAT and medication costs. Many employers also offer EAP programs that pay for an initial assessment.
Was the DEA X-waiver requirement for buprenorphine removed in Pennsylvania?
Yes — federal Congress eliminated the X-waiver in December 2022, so any Pennsylvania clinician with a DEA registration can now prescribe buprenorphine for OUD. Continuing-education requirements apply; training is free through Providers Clinical Support System (PCSS) and SAMHSA.
How often will I need to visit MAT programs in Pennsylvania?
Early in treatment, visits are weekly — sometimes daily for methadone induction. After stabilization, buprenorphine patients typically visit monthly, and methadone patients may qualify for take-home doses reducing visits to bi-weekly or monthly. Naltrexone injections are monthly.
Can I bring someone to my first mat visit in Pennsylvania?
Yes. Most Pennsylvania MAT programs allow a support person at intake and can include family in counseling with your permission. Having a trusted person to drive you, help with paperwork, and understand the plan is highly encouraged.
Do I need to fast before my first mat appointment?
No fasting is required for routine MAT labs in Pennsylvania. Eating a light meal before the visit is recommended to reduce nausea risk with the first medication dose. Hydration is helpful, especially for urine drug-screen collection.
Is constipation on mat a serious problem?
Constipation is one of the most common and persistent mat side effects. Daily fluids, fiber, stool softeners, and an over-the-counter laxative like polyethylene glycol are first-line. If severe, your Pennsylvania clinician may prescribe a peripherally acting opioid-receptor antagonist.
Will pediatricians in Pennsylvania know how to care for my MAT-exposed baby?
Yes. Pennsylvania pediatricians and neonatologists receive training on caring for infants with prenatal opioid exposure. Eat, Sleep, Console protocols, parental involvement, and compassionate postpartum care are standard. Share your MAT history openly so the team can tailor monitoring.
Do Pennsylvania MAT programs offer trauma-specific counseling?
Yes. Many Pennsylvania programs employ trauma-informed clinicians trained in EMDR, TF-CBT, or Seeking Safety. Trauma and OUD frequently co-occur; dual-focused counseling improves MAT retention and reduces relapse compared to substance-use counseling alone.
Can I travel internationally with mat from Pennsylvania?
Yes, with proper documentation. Bring a letter from your Pennsylvania MAT prescriber, medication in its original pharmacy container, and check destination-country rules — some countries restrict methadone and buprenorphine. The International Narcotics Control Board maintains destination-country guidance.
Other Treatment Options in Pennsylvania
Medication-Assisted Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)






































