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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Elev8 Center of New Jersey

Situated in Newark, NJ, Elev8 Center of New Jersey delivers a wide array of services for addiction recovery. The center features residential detox programs and provides around-the-clock residential support, concentrating on short-term residential treatment. Employing methods like 12-step facilitation, anger management, and brief intervention, the facility serves adults and young adults of diverse backgrounds. Elev8 Center is particularly attuned to the needs of adult males and females, including those who have faced intimate partner or domestic violence. With a dedication to high standards of care, this center stands out as an excellent option for those in need of targeted and effective rehabilitation solutions.

Elijahs House Treatment Center

Elijah's House Treatment Center, located in Pasadena, CA, specializes in detox and rehabilitation for substance abuse. This center features inpatient care within a nurturing atmosphere. Emphasizing 12-step methodology, anger management strategies, and brief intervention techniques, the treatment is customized to meet the diverse needs of each patient. It serves both adult men and women, including those who have faced domestic or intimate partner violence. Catering to adults and seniors of all genders, Elijah's House Treatment Center is committed to delivering exceptional care in a supportive environment. If you or someone you know is searching for thorough addiction recovery options, this facility provides a well-organized and effective approach to healing.

Elizabeth L Sturz Outpatient Center

The Elizabeth L Sturz Outpatient Center, situated in Bronx, NY, delivers extensive programs for substance abuse recovery and expert support for those facing concurrent serious mental health challenges. This facility features intensive outpatient care, general outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing therapeutic strategies such as anger management, brief intervention, and cognitive behavioral therapy, the center supports adult men and women, including survivors of intimate partner or domestic violence. The Elizabeth L Sturz Outpatient Center provides personalized treatment for all ages, from children and adolescents to adults, prioritizing effective and proven methods.

Elkton Comprehensive Treatment Center

Nestled in Elkton, Maryland, Elkton Comprehensive Treatment Center delivers outpatient addiction recovery services for adults and adolescents. The center offers diverse treatment options such as methadone, buprenorphine, or naltrexone-assisted outpatient care, general outpatient services, and tailored programs for expectant and new mothers. They employ therapeutic modalities including anger management, brief intervention, and cognitive behavioral therapy to combat substance dependence. Elkton Comprehensive Treatment Center is dedicated to providing personalized care for both men and women, ensuring a supportive setting for effective recovery.

Elm Tree Clinic
Lowell, MA

Elm Tree Clinic, situated in Lowell, MA, delivers outpatient treatment for adults and young adults dealing with substance use issues and co-existing significant mental health conditions. The facility focuses on tailored care through relapse prevention strategies, therapy for substance use disorders, and telehealth options. Emphasizing personalized treatment, Elm Tree Clinic adapts its programs to fulfill the distinct requirements of every individual. The center offers outpatient services including methadone/buprenorphine and naltrexone treatment for both men and women. Dedicated to high-quality care, Elm Tree Clinic fosters a nurturing atmosphere for individuals pursuing thorough addiction recovery services.

Elm Tree Clinic
Quincy, MA

Elm Tree Clinic located in Quincy, MA, provides outpatient treatment for substance use disorders and co-occurring issues for both adults and children. Their methodology incorporates strategies for preventing relapse, as well as counseling and telehealth services. They offer individualized programs that specifically address the requirements of both adults and young adults. In addition to standard outpatient services, the clinic provides treatment options such as methadone, buprenorphine, or naltrexone. Elm Tree Clinic also features gender-specific programs for men and women, fostering a nurturing atmosphere for recovery. Experience exceptional care and customized treatment at this dedicated facility focused on supporting individuals in their journey toward lasting recovery.

Ellen OBrien Gaiser Addiction Center

Situated in Butler, PA, the Ellen OBrien Gaiser Addiction Center specializes in treatment programs aimed at adults and young adults dealing with substance use issues. The facility offers a range of services including intensive outpatient programs, standard outpatient care, and medication-assisted treatments using methadone/buprenorphine or naltrexone. Emphasizing 12-step methods, anger management, and brief intervention strategies, this center is equipped to meet the distinct needs of adult men, women, and military personnel. Their programs are customized to provide individualized care to both male and female clients. For those looking for thorough addiction recovery solutions that are personalized, this center is committed to delivering high-quality support on your path to healing.

Elm Tree Clinic
Malden, MA

Situated in Malden, MA, the Elm Tree Clinic provides specialized outpatient services for individuals dealing with substance use and co-occurring disorders, serving both adults and children. Emphasizing personalized care and relapse prevention strategies, the clinic offers various services such as substance use counseling and telehealth therapy options. What makes Elm Tree Clinic unique is its customized treatment plans designed to accommodate adults and young adults from all backgrounds. Clients can access consistent outpatient support or opt for methadone/buprenorphine treatments, all delivered with empathy and a commitment to fostering enduring recovery.

Elmcor Youth and Adult Activities Inc

Elmcor Youth and Adult Activities Inc, located in Corona, NY, specializes in a wide range of substance abuse treatments for both adults and children facing serious mental health challenges. The center offers various levels of care, including intensive outpatient programs, outpatient services, and specific therapies involving methadone/buprenorphine or naltrexone. Its treatment methodologies emphasize anger management, short-term interventions, and cognitive behavioral therapy, effectively meeting the needs of adolescents, adult women, and individuals dealing with issues related to intimate partner violence. Catering to a diverse clientele of both men and women, Elmcor is dedicated to providing personalized care for every individual. The center is recognized for its multitude of treatment strategies and its unwavering dedication to offering high-quality rehabilitation services to those in need.

Elmcor Youth and Adult Activities Inc

Elmcor Youth and Adult Activities Inc, situated in Corona, NY, is a distinguished facility dedicated to aiding individuals struggling with addiction. They provide extended stay and round-the-clock residential services, employing proven therapeutic methods including anger resolution, short-term counseling, and cognitive restructuring. Elmcor addresses the distinct needs of adult males, adult females, and those with trauma histories, serving adults and young adults across genders. Their reputation for superior support and customized recovery strategies solidifies Elmcor Youth and Adult Activities Inc as a reliable option for comprehensive and impactful substance abuse recovery.

Elev8 Center New York LLC

Elev8 Center New York LLC, located in New York, NY, specializes in rehabilitation services for adult males facing challenges with substance abuse and concurrent mental health disorders. The facility provides a range of services including residential detox programs, round-the-clock care, and short-term residential options. Emphasizing 12-step programs, anger management techniques, and brief intervention strategies, the center supports individuals who have endured intimate partner violence, domestic abuse, and those impacted by HIV or AIDS. Catering to a diverse clientele of adults, seniors, and young adults, Elev8 Center New York LLC is committed to delivering exceptional, gender-specific treatment that addresses the specific requirements of male clients seeking thorough addiction recovery solutions.

Elev8 Center New York LLC

Elev8 Center New York LLC, based in New York, NY, provides an extensive selection of rehabilitation services specifically designed for adult men. This center focuses on detoxification, treatment for substance use, as well as addressing co-occurring mental health challenges in adults and emotional issues in children. Elev8 Center offers residential detox programs along with short-term residential options, ensuring around-the-clock support through methods including 12-step facilitation, anger management techniques, and brief intervention strategies. Specialized programs are available for clients dealing with both pain and addiction issues. Catering to adults, seniors, and young adults alike, Elev8 Center New York LLC is committed to delivering top-notch, gender-specific care for individuals in need of effective solutions for addiction recovery.

Elevate CCBHC
Waterloo, IA

Elevate CCBHC, located in Waterloo, IA, specializes in extensive treatment for substance use disorders and offers unique support for individuals facing severe mental health issues simultaneously. The center features a variety of outpatient treatment options, including intensive outpatient programs and medication-assisted therapies such as methadone and buprenorphine or naltrexone. Their therapeutic methods encompass anger management techniques, brief interventions, and cognitive behavioral therapy. With programs specifically designed for active military personnel, teenagers, and adult males, Elevate CCBHC addresses the needs of a wide audience. They provide dedicated support for adults and seniors of all genders, ensuring effective care for those on the path to recovery from addiction and mental health difficulties.

Elevate Health and Wellness

Elevate Health and Wellness, situated in Westport, CT, delivers a complete spectrum of recovery programs designed for those aiming to conquer addiction and associated mental health challenges. The facility features robust outpatient treatment, standard outpatient care, and outpatient detox, all grounded in proven techniques like brief counseling, cognitive behavioral strategies, and motivational dialogue. Tailored offerings exist for active military, young people, and adult men. Services are accessible to adults and individuals under 18 of any gender. Elevate Health and Wellness is committed to high-standard care and encouragement, guiding individuals toward sustained healing and enhanced health.

Elizabeth Layton Center

The Elizabeth Layton Center, located in Paola, KS, provides outpatient care for individuals of all ages facing substance use challenges alongside significant mental health concerns. They offer specialized programs such as anger management, brief interventions, and cognitive behavioral therapy. This institution is equipped to address complex cases involving dual diagnoses of mental health and substance use disorders, as well as those involved with the criminal justice system. The Elizabeth Layton Center is committed to delivering excellent, person-centered support to adults and seniors, utilizing proven therapeutic methods and tailored recovery strategies to foster sustained healing and enhanced mental wellness.

Elite Care Inc
Newport Beach, CA

Situated in Newport Beach, CA, Elite Care Inc delivers a wide variety of substance use recovery services for adults, including support for those facing concurrent mental health challenges. The facility offers intensive outpatient services, outpatient care, and daytime treatment programs, all customized to meet each person's unique requirements. Emphasizing 12-step facilitation, anger management techniques, and brief intervention strategies, Elite Care Inc serves both men and women, as well as individuals who have gone through traumatic experiences. Their dedicated programs aimed at young adults assure that everyone receives individualized attention in a nurturing atmosphere. Opt for Elite Care Inc to experience high-quality, empathetic treatment in a welcoming environment.

Elite Houses of Sober Living
Chicago Heights, IL

Elite Houses of Sober Living, situated in Chicago Heights, IL, delivers thorough programs for individuals struggling with substance use disorders, serving both adults and young adults. Their services include intensive outpatient, general outpatient, and medication-assisted treatment options (methadone, buprenorphine, or naltrexone). Employing approaches such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center supports adult men and women. They also provide specialized care for survivors of intimate partner or domestic violence, ensuring personalized, high-quality treatment for all.

Ellen OBrien Gaiser Addiction Center

The Ellen OBrien Gaiser Addiction Center, situated in Butler, PA, offers complete care for substance use disorders within a nurturing setting. This facility provides extended, brief, and round-the-clock inpatient services, serving adult men, women, and young adults. Their specialized treatment modalities include 12-step encouragement, strategies for managing anger, and brief intervention techniques. Notably, they also have distinct programs designed for active duty military members. By emphasizing personalized treatment plans, the center delivers excellent addiction recovery for both male and female patients. For those in search of effective and customized rehabilitation, this institution is committed to assisting individuals in conquering addiction and attaining enduring sobriety.

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Eliot Community Human Services, situated in Everett, MA, delivers a full spectrum of services for individuals struggling with substance use and those managing co-occurring mental health and emotional health challenges. Their programs cater to adults with dual diagnoses and children experiencing serious emotional disturbances. Patients can access outpatient services, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside traditional outpatient support. The center employs various therapeutic modalities like anger management, brief intervention, and cognitive behavioral therapy. Eliot Community Human Services provides specialized care across diverse demographics, including active military, teens, adult men, general adults, and seniors, ensuring personalized recovery journeys for all.

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Saint Paul, MN

Situated in Saint Paul, MN, Elite Recovery specializes in high-quality substance use rehabilitation for adult males. The center offers a range of services, including intensive outpatient treatment, standard outpatient care, and daytime programs, focusing on anger management, brief intervention techniques, and cognitive behavioral therapy. Customized treatment plans are available for adult men, LGBTQ clients, and individuals dealing with dual diagnoses. Elite Recovery accommodates adults across different life stages, including young adults and seniors, ensuring thorough and inclusive care. With a dedication to excellence and tailored programs, this facility is recognized as a leading choice for those in need of effective and compassionate addiction recovery solutions.

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Elizabeth Layton Center, located in Ottawa, KS, offers outpatient care for individuals of all ages struggling with substance use disorders alongside mental health concerns. Their services include anger management, brief intervention strategies, and cognitive behavioral therapy. The center is particularly adept at assisting those with co-occurring disorders and individuals navigating the legal system, serving adults and seniors across all gender identities. Prioritizing effective, research-backed methods, Elizabeth Layton Center develops personalized recovery plans to meet the distinct requirements of everyone pursuing freedom from addiction and mental health struggles.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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