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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Eleanor Health
Hickory, NC

Eleanor Health, located in Hickory, NC, provides outpatient services for adults dealing with substance use disorders, with an emphasis on addressing significant mental health challenges that may coexist. The center also has programs designed specifically for children experiencing severe emotional issues. By employing techniques such as cognitive behavioral therapy and motivational interviewing, Eleanor Health delivers personalized care through short-term interventions. The treatment offerings include outpatient options such as methadone or buprenorphine for both adult males and females, as well as young adults. With its customized strategies and dedication to high standards of care, Eleanor Health is an excellent option for individuals seeking thorough assistance on their path to recovery.

Eleanor Health
Edison, NJ

Situated in Edison, NJ, Eleanor Health delivers outpatient services for adults and young adults dealing with substance use issues. The center is adept at addressing co-occurring substance use disorders alongside significant mental health challenges in adults and serious emotional issues in younger individuals. The offerings comprise outpatient treatment with methadone, buprenorphine, or naltrexone, along with standard outpatient therapy, short intervention sessions, cognitive behavioral therapy, and motivational interviewing techniques. Eleanor Health emphasizes personalized care, catering to both male and female clients. Its dedication to high-quality treatment and customized strategies positions it as a vital option for those in need of thorough addiction recovery support.

Eleanor Health
Verona, NJ

Situated in Verona, NJ, Eleanor Health stands as a premier outpatient facility dedicated to aiding adults and young adults in their journey toward recovery from substance use. The center excels in addressing co-occurring disorders, providing specialized support for those managing significant mental health challenges or emotional distress. Eleanor Health is committed to personalized care, utilizing scientifically proven methods like cognitive behavioral therapy and motivational interviewing. The facility also offers bespoke programs designed to address the distinct requirements of every individual. Eleanor Health provides a full spectrum of care, including outpatient services for methadone, buprenorphine, or naltrexone, alongside general outpatient treatment, ensuring a thorough and empathetic recovery experience for all clients.

Eleanor Health
San Antonio, TX

Eleanor Health in San Antonio, TX, delivers outpatient care for adults and young adults battling substance use disorders. The facility excels in addressing dual diagnoses, where substance use coexists with significant mental health conditions. Their treatment philosophy centers on personalized plans, utilizing therapeutic techniques such as cognitive behavioral therapy and motivational interviewing. Clients have access to outpatient medication options including methadone, buprenorphine, and naltrexone, alongside brief intervention strategies. Eleanor Health is committed to providing tailored support for every individual, fostering a complete and successful recovery journey for those facing addiction and mental health issues.

Eleanor Health
Durham, NC

Eleanor Health, situated in Durham, NC, delivers extensive outpatient addiction recovery services for adults and adolescents. The center focuses on addressing co-occurring addiction and significant mental health challenges in children and young adults. They employ tailored strategies such as brief counseling, cognitive behavioral techniques, and motivational engagement. Eleanor Health offers outpatient medication-assisted treatment, including methadone, buprenorphine, or naltrexone, alongside standard outpatient support. Dedicated to high-quality, individualized support, this establishment welcomes both men and women pursuing scientifically proven therapies for addiction and psychological wellness.

Eleanor Health
Cherry Hill, NJ

Eleanor Health, situated in Cherry Hill, NJ, stands as a leading facility dedicated to outpatient treatment for substance use issues affecting adults and adolescents. This center is particularly adept at addressing dual diagnoses, integrating care for co-occurring substance use disorders with significant mental health conditions in adults, or serious emotional disruptions in younger individuals. Eleanor Health offers diverse treatment modalities, such as outpatient programs utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Their tailored strategies encompass brief intervention techniques, cognitive behavioral therapy, and motivational interviewing. Emphasizing personalized care for both male and female clients, Eleanor Health delivers exceptional and complete treatment to support individuals on their journey to sustained recovery.

Eleanor Health
Columbus, OH

Eleanor Health, situated in Columbus, OH, specializes in outpatient services aimed at addressing substance use disorders and serious mental health issues in adults, along with severe emotional challenges in children. The facility provides various treatment options, including outpatient therapy with methadone, buprenorphine, or naltrexone, alongside traditional outpatient services. It incorporates research-backed methods such as cognitive behavioral therapy and motivational interviewing. Committed to personalized treatment, Eleanor Health supports individuals of all genders and ages, fostering a nurturing atmosphere for healing. If you or someone you care about is looking for comprehensive addiction treatment, this center delivers high-quality care customized to fit specific requirements.

Eleanor Health Seattle

Eleanor Health Seattle, located in Seattle, WA, provides outpatient treatment for substance use issues targeting both adults and young adults. The center specializes in addressing co-occurring disorders related to substance use and significant mental health conditions in adults, as well as emotional challenges in younger clients. Offering a customized approach, Eleanor Health Seattle delivers a variety of therapeutic services such as brief interventions, cognitive behavioral therapy, and motivational interviewing. Additionally, the facility provides outpatient options for methadone/buprenorphine and naltrexone treatments, ensuring thorough support for all clients, regardless of gender. Committed to delivering high-quality, evidence-based services, Eleanor Health Seattle assists individuals in their recovery journey.

El Paso Veterans Affairs Healthcare

Situated in El Paso, TX, El Paso Veterans Affairs Healthcare delivers focused rehabilitation services designed for adults and young adults grappling with substance abuse and concurrent severe mental health challenges. The center features intensive outpatient care, outpatient programs, as well as outpatient treatments using methadone, buprenorphine, or naltrexone. With an emphasis on 12-step support, anger management techniques, and brief interventions, this institution customizes its offerings to address the specific requirements of adult men, adult women, and those affected by intimate partner or domestic violence. This facility provides effective treatment for both male and female clients, ensuring thorough and quality care for individuals on their path to recovery.

El Centro Family Health

El Centro Family Health in Roy, NM, provides targeted outpatient services for those struggling with substance use disorders and concurrent mental health challenges. The center employs various evidence-supported treatment methods, such as cognitive behavioral therapy, anger management, and short-term interventions. It features specialized programs designed for adult clients, particularly pregnant or postpartum women. The facility caters to both adults and seniors, offering gender-specific programs for men and women. Emphasizing high-quality care and tailored support, this center facilitates outpatient treatment options with methadone, buprenorphine, or naltrexone, ensuring that recovery is both accessible and effective for individuals seeking help.

El Paso Behavioral Health System

Situated in El Paso, TX, the El Paso Behavioral Health System provides a wide range of rehabilitation services aimed at those facing addiction and concurrent mental health issues. The center offers inpatient detoxification and treatment solutions designed for both adults and younger populations. It features specific programs for active-duty military members, veterans, and individuals with co-occurring conditions, leveraging evidence-based methodologies like cognitive behavioral therapy and motivational interviewing to ensure top-notch care. The El Paso Behavioral Health System is committed to offering supportive and empathetic treatment for all clients, regardless of gender, empowering them on their path to recovery.

El Regreso Foundation Inc

El Regreso Foundation Inc, situated in Brooklyn, NY, delivers outpatient substance use disorder treatment incorporating anger management, brief intervention, and cognitive behavioral therapy. The center features dedicated programs for active military personnel, teenagers, and adult males. Serving adults and young people, this facility welcomes individuals of any gender. El Regreso Foundation Inc distinguishes itself with customized treatment strategies and a thorough recovery methodology, emphasizing high-quality support. For those in need of impactful substance use treatment within a nurturing setting, this organization is committed to aiding your path to abstinence.

El Regreso Inc
Brooklyn, NY

El Regreso Inc, situated in Brooklyn, NY, is a dedicated recovery facility providing extended residential stays and round-the-clock support for women of all ages grappling with addiction. Our specialized programs are designed for adult women, seniors, and young adults, employing proven methods like 12-step facilitation, anger management techniques, and brief intervention strategies. We offer distinct support for adult women, and those who have experienced intimate partner violence, domestic abuse, or sexual trauma. El Regreso Inc is committed to delivering excellent care in a secure and nurturing setting for those on their journey to sustained sobriety.

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In Embudo, New Mexico, El Centro Family Health provides outpatient services for individuals of all ages struggling with substance use, including those with co-occurring mental health challenges. The clinic offers distinct programs for adults and for women who are pregnant or have recently given birth. Treatment modalities include anger management techniques, cognitive behavioral therapy, and brief intervention strategies. El Centro Family Health specializes in outpatient care involving methadone, buprenorphine, or naltrexone, alongside general outpatient support. The center serves adults and seniors across all genders, committed to delivering personalized, high-quality care within a nurturing setting, positioning it as a vital provider of extensive recovery support.

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El Centro Family Health, situated in Truchas, New Mexico, provides outpatient care for individuals of all ages grappling with substance use disorders, including those with co-occurring mental health conditions. The center features distinct programs designed for adults and for women who are pregnant or have recently given birth, along with specialized support for older adults. Therapeutic interventions encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Emphasizing outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, El Centro Family Health delivers personalized care to all clients. Its dedication to high-quality, impactful recovery services solidifies El Centro Family Health as a reliable option for holistic addiction treatment.

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El Centro Family Health, situated in Las Vegas, NM, provides extensive rehabilitation for adults and older adults facing addiction and concurrent mental health challenges. This center employs outpatient treatment methods, including anger management, cognitive behavioral therapy, and brief intervention strategies. Tailored programs are available for adult women, as well as expectant and new mothers. Committed to high-standard care, El Centro Family Health offers outpatient treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Serving all genders, this facility is devoted to supporting individuals in their journey towards sustained recovery and enhanced mental wellness.

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Nestled in Espanola, NM, El Centro Family Health delivers thorough outpatient care for individuals of all ages grappling with substance use and co-occurring mental health conditions. Their services encompass a variety of scientifically-backed therapies, such as cognitive behavioral therapy and anger management techniques. They also feature specialized programs designed for adult women, including those who are pregnant or have recently given birth. El Centro Family Health is dedicated to personalized treatment plans for adults and seniors across all genders. Clients can anticipate excellent care and encouragement, whether they require standard outpatient services or methadone/buprenorphine treatment.

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Nestled in Las Vegas, NM, El Centro Family Health provides outpatient care for substance use disorders affecting adults and children, with a particular focus on those experiencing co-occurring mental health challenges. The facility features dedicated programs for adult women, including those who are pregnant or have recently given birth. Treatment plans are also customized for adult men and women of all ages, including seniors. Therapeutic modalities employed include anger management, brief intervention strategies, and cognitive behavioral therapy. The range of services includes outpatient treatment with methadone, buprenorphine, or naltrexone, as well as general outpatient support. El Centro Family Health is recognized for its holistic and personalized strategy to treating addiction and mental health concerns, delivering excellent care to all individuals pursuing recovery.

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Nestled in Espanola, NM, El Centro Family Health delivers extensive outpatient care for both substance use disorders and co-occurring mental health challenges across all age groups, from children to seniors. They offer distinct programs designed for adult women, expectant and new mothers, and serve adults and older adults of any gender. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. A key feature of El Centro Family Health is their provision of outpatient treatment utilizing methadone, buprenorphine, or naltrexone, all delivered with a commitment to personalized client care. This facility is recognized for its dedication to effective and high-quality support, making it a reliable option for individuals seeking customized recovery services in a nurturing setting.

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The El Dorado Community Service Center, situated in Inglewood, CA, provides outpatient services for adults and young adults facing substance use challenges. Their approach incorporates motivational interviewing, relapse prevention strategies, and dedicated counseling to deliver personalized treatment plans. Catering to both men and women, the center fosters a welcoming atmosphere. A distinguishing feature is their specialized outpatient programs for methadone, buprenorphine, or naltrexone, positioning them as a leading provider of addiction care locally.

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Situated in Decatur, IL, Elements at Crossing Healthcare delivers a wide range of services for those battling addiction. The center specializes in detox, treatment for substance use disorders, and tailored support for adults facing both substance abuse and serious mental health issues, as well as for children dealing with emotional challenges. With programs such as intensive outpatient care, outpatient detox services, and various therapeutic modalities including 12-step programs and anger management, the facility serves both adult males and females, including those with trauma histories. Committed to providing high-quality care for adults and young adults irrespective of gender, Elements at Crossing Healthcare strives to support individuals in achieving sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)