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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Easterseals Blake Foundation

Easterseals Blake Foundation in Tucson, Arizona, delivers extensive outpatient care for individuals battling substance use and co-occurring mental health challenges. They also support children experiencing emotional difficulties. The facility features targeted programs for teenagers, adult men, and women, serving a diverse clientele from young adults to seniors. Their therapeutic methods encompass anger management techniques, cognitive behavioral therapy, and motivational incentives. Prioritizing high-quality support, this center provides outpatient options for methadone, buprenorphine, or naltrexone treatment alongside general outpatient services, tailoring recovery plans for all genders aiming for well-being.

Ebb Tide Treatment LLC
West Palm Beach, FL

Ebb Tide Treatment LLC, situated in West Palm Beach, FL, provides a range of rehabilitation services with a focus on substance use treatment and transitional housing specifically for adult males. This center offers various levels of care, including intensive outpatient treatment, outpatient day programs, and additional outpatient services. Their approach incorporates elements such as 12-step programs, anger management, and short-term intervention techniques. Ebb Tide Treatment LLC also features specialized programs for active duty military members, adult males, and those who have faced incidents of intimate partner violence. Emphasizing the treatment of co-occurring substance use disorders alongside serious mental health issues, the center is dedicated to delivering high-quality care in a supportive environment tailored to adults, seniors, and young adults on their path to recovery.

Ecker Center for Behavioral Health

The Ecker Center for Behavioral Health, situated in Elgin, IL, specializes in extensive treatment for individuals dealing with substance use issues, alongside significant mental health challenges. This center provides a variety of care options including intensive outpatient programs and outpatient services, as well as targeted treatments involving methadone/buprenorphine or naltrexone. By employing evidence-based methods such as cognitive behavioral therapy and the Matrix Model, the center customizes its treatment plans to meet the unique needs of each client. With a commitment to high-quality care and tailored programs, the facility accommodates both men and women, establishing itself as an essential support system for those in need of effective and empathetic rehabilitation in the Elgin region.

Edgefield Recovery Center

Edgefield Recovery Center, situated in Cheneyville, LA, delivers exceptional addiction treatment for adults and young adults. This establishment is equipped to handle individuals facing the dual challenges of addiction and significant mental health conditions. Through its residential and short-term residential options, Edgefield Recovery Center utilizes diverse therapeutic strategies such as 12-step facilitation, anger management techniques, and brief intervention. The center serves adult men and women, along with patients experiencing co-occurring mental health and substance use disorders. Edgefield Recovery Center's dedication to personalized treatment plans and scientifically-backed methods guarantees effective recovery support.

Edgewater Recovery Center

Edgewater Recovery Center located in Morehead, KY, provides an extensive array of treatment options for adults dealing with substance use disorders alongside serious mental health challenges, as well as emotional issues in children. The center offers various treatment formats, including intensive outpatient, outpatient, and standard outpatient programs, employing evidence-driven methods such as cognitive behavioral therapy, anger management, and motivational enhancement techniques. Customized programs are designed for both men and women, as well as individuals who have faced domestic or intimate partner violence. Edgewater accommodates clients of all genders and age ranges, focusing on personalized care and support for individuals on their path to recovery.

El Cajon Comprehensive Trt Center

In El Cajon, CA, El Cajon Comprehensive Trt Center provides outpatient services for detoxification and addiction recovery. They employ methods including anger management, cognitive behavioral therapy, and brief intervention, serving adult men and women, along with active duty military. This center focuses on adult and young adult clients, offering tailored support for both men and women. El Cajon Comprehensive Trt Center is a dedicated provider of high-quality, varied addiction treatment in the El Cajon community.

Eastridge Health Systems

Eastridge Health Systems, situated in Martinsburg, WV, delivers thorough outpatient services for individuals of all ages struggling with substance use disorders and accompanying mental health challenges. The center is equipped to provide targeted support for LGBTQ+ individuals, expectant and new mothers, and those with co-occurring diagnoses. Employing approaches such as 12-step facilitation, cognitive behavioral therapy, and brief intervention strategies, the program crafts personalized recovery paths. Eastridge Health Systems offers outpatient medication-assisted treatment, including methadone, buprenorphine, and naltrexone, within a nurturing setting. Catering to both men and women, this institution is dedicated to delivering high-quality care for those pursuing freedom from substance use and related mental health conditions.

Eastridge Health Systems
Kearneysville, WV

Eastridge Health Systems, situated in Kearneysville, WV, provides extensive outpatient treatment for adults struggling with substance use and accompanying mental health challenges. This center is dedicated to delivering structured outpatient services that emphasize 12-step programs, brief interventions, and cognitive behavioral therapy. Eastridge Health Systems features customized treatment plans for individuals experiencing dual diagnoses, ensuring personalized care for both adults and minors. Celebrating inclusivity, the facility supports both men and women in their pursuit of effective, evidence-supported treatment within a nurturing atmosphere.

Egyptian Public and Mental Health Dept

The Egyptian Public and Mental Health Dept in Harrisburg, IL, provides targeted outpatient services addressing substance use and co-occurring mental health issues for both adults and children. The center employs methods such as 12-step programs, anger management strategies, and brief interventions to create personalized treatment plans that cater to unique challenges. With specific programs designed for active military personnel, teenagers, and adult males, this facility ensures customized assistance. Catering to a diverse clientele across different ages and genders, the center emphasizes high-quality care and evidence-supported methods. For individuals in need of thorough and effective rehabilitation solutions, the Egyptian Public and Mental Health Dept stands out as a reliable resource in Harrisburg.

El Centro Family Health

El Centro Family Health, located in Taos, NM, provides outpatient treatment for substance use disorders, along with specialized support for adults facing severe mental health challenges or for children experiencing significant emotional difficulties. The facility offers various treatment options, including outpatient services with methadone, buprenorphine, or naltrexone, as well as regular outpatient programs. Techniques such as cognitive behavioral therapy, brief interventions, and anger management are utilized in the treatment process. Programs designed specifically for adult women, pregnant or postpartum individuals, and services catering to both adult and senior populations ensure a comprehensive and personalized approach to care. El Centro Family Health stands out as a trusted provider for those in need of effective rehabilitation options.

El Centro Family Health

El Centro Family Health, located in Ribera, NM, specializes in outpatient treatment for adults dealing with substance use issues, particularly those who also face mental health challenges and emotional difficulties in children. The center employs various therapeutic methods, such as cognitive behavioral therapy, anger management, and brief interventions. Additionally, there are tailored programs available for adult women as well as those who are pregnant or in the postpartum period. The facility emphasizes care for adults and seniors and provides outpatient treatment options including methadone, buprenorphine, or naltrexone. Catering to both men and women, this center is dedicated to delivering exceptional support and services for individuals in need of extensive rehabilitation.

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Eastport Healthcare Inc, located in Machias, ME, provides extensive outpatient services for substance use disorders for both adults and children who also face mental health challenges. The facility features targeted programs for clients within the criminal justice system, as well as those dealing with anger issues. Their treatment modalities encompass cognitive behavioral therapy and strategies for relapse prevention. Customized outpatient options using methadone/buprenorphine or naltrexone are also offered. Committed to delivering high-quality care, this center caters to both men and women, fostering a nurturing environment for recovery. If you're looking for effective rehabilitation support in the Machias region, Eastport Healthcare Inc is here to assist you on your path toward health and recovery.

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Berkeley Springs, WV

Eastridge Health Systems, located in Berkeley Springs, WV, provides extensive outpatient care for individuals, both young and adult, addressing substance abuse and co-occurring psychological challenges. Through scientifically validated methods such as cognitive behavioral therapy and 12-step program integration, the center delivers personalized treatment plans. Distinct services are offered for expectant and new mothers, as well as for those with multiple diagnoses. Eastridge Health Systems prioritizes high-standard care within a nurturing setting conducive to healing. The center supports clients in their pursuit of sustained abstinence by offering outpatient treatment with methadone, buprenorphine, or naltrexone. Services are accessible to both male and female individuals seeking proficient and empathetic recovery assistance.

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Situated in Morehead, KY, the Edgewater Mens Campus delivers extensive rehabilitation services for adult males within a nurturing and secure setting. This center is dedicated to offering long-term residential care, which includes detox support and round-the-clock supervision. Their treatment strategy integrates 12-step methods, anger management, and short intervention techniques to tackle issues related to substance abuse and concurrent mental health challenges. Distinctive programs are available for those who have faced intimate partner violence, domestic violence, and sexual trauma. Aiming to serve adult men, including seniors and younger adults, this facility tailors its services to the distinct requirements of every individual, ensuring effective and high-quality recovery.

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Educational Alliance Inc in New York, NY, provides a range of long-term residential options, along with residential detoxification and around-the-clock care for those seeking treatment for substance use. The center is known for its customized care strategies, incorporating techniques such as 12-step facilitation, anger management, and brief intervention. Their specialized programs are designed for adult men and women, as well as individuals impacted by intimate partner or domestic violence. Catering to adults and young adults of any gender, the facility is dedicated to offering exceptional, individualized support to assist clients in their recovery journey.

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Educational Alliance Inc., located in New York, NY, delivers outpatient services focused on detoxification and substance use disorder therapy for both young people and adults. The center is equipped to offer distinct support for adult men, adult women, and adolescent populations, welcoming clients of all genders. Employing therapeutic strategies that include 12-step facilitation, anger management techniques, and brief intervention methods, the organization is dedicated to providing thorough and customized treatment. Educational Alliance Inc. distinguishes itself through its high standard of care and programs specifically designed to meet individual needs, offering strong assistance to those pursuing recovery from addiction. For individuals searching for a treatment facility that emphasizes individualized attention and scientifically-backed methods, this New York City establishment is a trustworthy option.

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Situated in Anton Chico, NM, El Centro Family Health delivers extensive outpatient treatment for substance use aimed at both adults and children experiencing concurrent mental health conditions. The facility features dedicated programs specifically for adults and women who are pregnant or in the postpartum period, emphasizing techniques such as cognitive-behavioral therapy, anger management, and short-term interventions. Customized outpatient options for methadone/buprenorphine or naltrexone treatment are provided in addition to standard outpatient services. Catering to adults and seniors of all genders, this center is committed to offering high-quality care and assistance for those working towards overcoming addiction and mental health difficulties.

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El Centro Family Health, situated in Penasco, NM, provides outpatient treatment for individuals grappling with substance use issues, including both adults and children facing significant mental health challenges. The center features targeted programs specially designed for women who are pregnant or in the postpartum phase. By emphasizing therapeutic techniques such as cognitive behavioral therapy, anger management, and short-term interventions, El Centro Family Health customizes its approach to meet the unique needs of each client. The services offered encompass outpatient treatment options including methadone, buprenorphine, and naltrexone. Catering to individuals of all genders, including seniors, this facility is committed to offering compassionate care within a nurturing setting. If you are looking for effective and tailored assistance for overcoming addiction, this center is focused on helping you achieve a sustainable recovery.

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Situated in Coyote, NM, El Centro Family Health delivers targeted rehabilitation services for those struggling with substance use disorders alongside mental health issues in both adults and children. The facility offers outpatient treatments with methadone, buprenorphine, or naltrexone, along with regular outpatient support and therapeutic interventions such as anger management and cognitive behavioral therapy. Specialized programs are designed specifically for adult women, including those who are pregnant or postpartum. Catering to adults and seniors across all genders, this center prioritizes high-quality care through a variety of evidence-based methods. If you are looking for thorough and personalized treatment, El Centro Family Health is committed to guiding you on your recovery path.

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Situated in Springer, NM, El Centro Family Health delivers extensive outpatient treatment for individuals of all ages grappling with significant mental health challenges linked to substance use. The facility features tailored programs specifically designed for pregnant and postpartum women, as well as elderly clients and adult women. A variety of therapeutic methods are employed, including anger management strategies, cognitive behavioral therapy, and short-term interventions. Committed to high-quality care, El Centro Family Health also provides outpatient options for methadone, buprenorphine, or naltrexone. This center serves both men and women, fostering a welcoming atmosphere for those on their journey to recover from substance use disorders alongside mental health issues.

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Located in Wagon Mound, NM, El Centro Family Health offers comprehensive substance use treatment for adults and children with co-occurring serious mental health illnesses or emotional disturbances. This facility provides outpatient services including methadone/buprenorphine treatment and regular outpatient care. With a focus on anger management, brief intervention, and cognitive behavioral therapy, the center caters to adult women, pregnant/postpartum women, adults, and seniors of all genders. El Centro Family Health is dedicated to providing quality care and support to individuals seeking effective rehabilitation programs in a welcoming and inclusive environment.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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