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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Ethan Health
Burlington, KY

Ethan Health, situated in Burlington, KY, delivers an extensive array of rehabilitation services designed for both adults and young adults dealing with substance use challenges and related mental health conditions. The center features intensive outpatient programs, outpatient detox, and various outpatient services grounded in evidence-based methodologies, including 12-step facilitation, cognitive behavioral therapy, and brief interventions. With specific programs aimed at adult men, adult women, and active duty military personnel, Ethan Health is dedicated to providing customized care tailored to the distinct needs of each client. Their focus on high-quality treatment and individualized support positions this facility as a premier choice for effective addiction recovery solutions.

Ethan Health
Richmond, KY

Ethan Health, situated in Richmond, KY, provides a wide array of substance abuse treatment options for adults. This center addresses both co-occurring substance use disorders and severe mental health conditions in adults, as well as significant emotional issues in children. The available services include intensive outpatient care, long-term residential treatment, and standard outpatient programs. By employing research-backed strategies such as brief interventions, cognitive behavioral therapy, and the Matrix Model, Ethan Health features distinct programs tailored for adult men, women, and individuals who have faced intimate partner or domestic violence. With a commitment to personalized care, the facility serves both male and female adults, guaranteeing effective and high-quality rehabilitation support.

Evanston Hospital
Evanston, IL

Situated in Evanston, IL, Evanston Hospital provides extensive addiction recovery services for both adults and young adults. This facility offers detoxification and treatment for substance use through various programs, including intensive outpatient, outpatient, and day treatment options. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, it customizes its treatment plans to meet the unique needs of each client. With a focus on gender-specific care for both men and women, Evanston Hospital supports individuals on their recovery journey. If you are in search of personalized and evidence-driven addiction treatment, this center's dedication to high-quality care makes it an excellent option for those aiming for sustained sobriety.

Evansville Comprehensive Treatment Ctr

Evansville Comprehensive Treatment Center, located in Evansville, IN, provides extensive outpatient care for individuals pursuing sobriety. The facility offers tailored programs, including methadone, buprenorphine, and naltrexone treatments, alongside general outpatient services. Their therapeutic approach incorporates 12-step facilitation, anger management, and brief intervention strategies. Serving adult men and women, as well as active duty military members and young adults, the center is dedicated to delivering effective support for sustained recovery and enhanced quality of life.

Evas Village
Paterson, NJ

Evas Village, located in Paterson, NJ, delivers thorough addiction recovery services and tailored support for individuals facing dual diagnoses of substance use disorders and significant mental health challenges, as well as emotional difficulties in young people. The facility features intensive outpatient, outpatient, and standard outpatient programs, employing therapeutic methods like anger management, motivational interviewing, and cognitive behavioral therapy. Evas Village offers specialized programs for active military personnel, adult men, and adult women, accommodating a wide range of patient needs. Open to adults and young adults of all genders, the center is committed to providing exceptional care and encouragement for those pursuing successful recovery within a supportive and understanding setting.

Evas Village
Paterson, NJ

Evas Village, situated in Paterson, NJ, delivers complete addiction recovery services and supportive housing for adults and adolescents. This establishment focuses on addressing dual diagnoses, specifically substance use disorders alongside significant mental health conditions. Clients benefit from extended residential stays featuring continuous supervision and employ proven therapeutic methods like cognitive behavioral therapy and anger management techniques. Evas Village serves adult males and those affected by domestic violence, intimate partner abuse, or sexual trauma. Committed to exceptional care and tailored interventions, Evas Village empowers individuals pursuing lasting sobriety.

Evergreen Behavioral LLC

Evergreen Behavioral LLC, located in Woburn, MA, delivers extensive treatment for substance use disorders while also addressing the complex needs of those with co-occurring mental health issues. This facility features a range of services including intensive outpatient programs, general outpatient care, and day treatment options, catering to adults and young adults of all genders. Emphasizing methods such as 12-step approaches, anger management, and brief intervention, the center customizes its programs to suit the distinct requirements of each individual. Evergreen Behavioral LLC is noted for its commitment to delivering high-quality care, particularly in its specialized offerings for clients facing dual diagnoses. Those in need of assistance with substance use or mental health concerns will find personalized and compassionate support within its welcoming atmosphere.

Evergreen Treatment Center

Evergreen Treatment Center, situated in Paramus, NJ, is dedicated to offering a wide range of addiction treatment options for both adults and teens. The center features inpatient detoxification services as part of its comprehensive care, utilizing methods like 12-step programming, brief interventions, and cognitive behavioral therapy. Evergreen Treatment Center excels in addressing the needs of individuals facing both mental health challenges and substance use disorders. With programs designed for men, women, and specialized services for adolescents, the facility is committed to delivering personalized and high-quality care to aid in the recovery process. For those in need of compassionate and effective substance use treatment, Evergreen Treatment Center is fully equipped to provide essential support and resources.

Evergreen Treatment Services

Situated in Seattle, WA, Evergreen Treatment Services specializes in outpatient treatment for individuals dealing with substance use issues, including both adults and young adults. This facility offers a range of services, including outpatient therapies utilizing methadone, buprenorphine, or naltrexone, as well as regular outpatient sessions and unique programs designed for adult men, women, and pregnant or postpartum individuals. The center employs proven methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies to facilitate the recovery process. With an emphasis on personalized care, Evergreen Treatment Services addresses the distinct needs of male and female clients, ensuring a holistic and customized approach to battling addiction.

Evergreen Treatment Services

Evergreen Treatment Services, situated in Seattle, WA, delivers outpatient care for individuals aged 18 and above struggling with substance use disorders. They offer medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. The facility also provides standard outpatient services and utilizes specialized therapeutic techniques including cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. Evergreen Treatment Services serves a diverse population, including adult men and women, and has specific programs designed for pregnant and postpartum individuals, as well as distinct age-focused tracks. Emphasizing individualized treatment and a nurturing atmosphere, this center is dedicated to guiding people toward successful recovery.

Evoke Wellness LLC
Hollywood, FL

Evoke Wellness LLC, located in Hollywood, FL, specializes in extensive addiction recovery services for both adults and young adults. The facility emphasizes detoxification, treatment for substance use, and targeted support for individuals dealing with dual diagnosis mental health issues. They offer both short-term and 24-hour residential detox programs. The center employs various therapeutic techniques, including cognitive behavioral therapy and anger management, to customize treatment plans. Unique programs are designed for adult men, adult women, and those with co-occurring conditions, ensuring tailored support. Evoke Wellness LLC is dedicated to delivering high-quality, evidence-based care in a nurturing atmosphere for those on their path to recovery.

Evolve Indy LLC
Indianapolis, IN

Evolve Indy LLC, located in Indianapolis, IN, delivers a wide range of rehabilitation services designed for both adults and young adults facing challenges related to substance use disorders and concurrent mental health issues. The center offers varied treatment options including intensive outpatient programs, long-term residential care, and standard outpatient services, utilizing effective methods like cognitive behavioral therapy and 12-step support. Additionally, clients have access to specialized programs aimed at adult men, adult women, and individuals who have undergone trauma. Emphasizing high-quality care and personalized treatment plans, Evolve Indy LLC is committed to assisting clients in their recovery journey and promoting overall well-being.

Evolve Recovery Center at Millbury LLC

Evolve Recovery Center at Millbury LLC, located in Millbury, MA, delivers targeted addiction treatment for adults, also addressing concurrent severe mental health disorders or emotional issues in youth. The center offers both residential and transitional living options, emphasizing 12-step principles, emotional regulation techniques, and brief therapeutic interventions. Their distinctive personalized methodology is designed for adults and young adults alike, ensuring care is precisely fitted to each person's distinct requirements. Open to both men and women, this establishment is dedicated to delivering superior, all-encompassing care to guide individuals toward lasting sobriety.

Evolve Recovery Center LLC

Evolve Recovery Center LLC, located in Toms River, NJ, provides extended residential and around-the-clock care for adults and young adults dealing with substance use disorders. The facility emphasizes a variety of treatment techniques, including 12-step facilitation, anger management, and brief interventions, all designed to create customized programs for each individual. Catering to both men and women, Evolve Recovery Center fosters a holistic and nurturing setting that promotes healing. Its dedication to high-quality care and personalized services positions it as a leading option for individuals looking for tailored addiction recovery solutions.

Evergreen Recovery Centers

Evergreen Recovery Centers, situated in Lynnwood, WA, provides a wide array of services aimed at treating addiction, designed to fit the unique requirements of each patient. This center offers detox services along with both outpatient and residential treatment options. Utilizing methods such as 12-step programs, brief interventions, and motivational interviewing, the center fosters a comprehensive recovery journey. Evergreen Recovery Centers emphasizes a personalized approach, serving adults as well as children and teenagers, with tailored programs available for both men and women. Discover exceptional care and individualized assistance at Evergreen Recovery Centers.

EvergreenHealth Monroe Recovery Center

EvergreenHealth Monroe Recovery Center in Monroe, WA, delivers extensive addiction recovery services. This hospital-based inpatient facility focuses on safe detoxification and holistic substance use treatment, fostering a caring atmosphere. Their therapeutic methods encompass 12-step program support, anger management techniques, and short-term intervention strategies. Tailored programs are available for adult men, adult women, and women who are pregnant or have recently given birth. Catering to adults and young adults of all genders, EvergreenHealth Monroe Recovery Center prioritizes individualized care plans, dedicating itself to offering excellent, scientifically-backed treatment for lasting recovery.

Excelsior Wellness Center

Located in Spokane, WA, Excelsior Wellness Center delivers a wide array of services aimed at treating substance use disorders along with various specialized programs. The center features transitional living arrangements, such as halfway houses and sober living homes, designed for both adults and seniors. Emphasizing the treatment of dual-diagnosis patients, it employs research-backed methods like cognitive behavioral therapy and contingency management. Excelsior Wellness Center is particularly notable for its dedicated programs for teenagers, individuals with a history of trauma, and those facing both mental health and substance use challenges. Its intensive outpatient and outpatient services provide adaptable and effective options for men and women on their journey to recovery.

Exodus House
Kewaskum, WI

Exodus House, situated in Kewaskum, WI, delivers extensive rehabilitation services and transitional housing for adult males dealing with addiction. This center is adept at addressing both substance use disorders and significant mental health issues in adults, along with severe emotional challenges in youth. Emphasizing long-term residential support with around-the-clock assistance, Exodus House applies proven methods such as 12-step programs, cognitive behavioral therapy, and anger management strategies. Notably, they offer targeted programs for those who have faced trauma. Serving a diverse clientele that includes adults, seniors, and younger individuals, this facility fosters a nurturing and organized setting that encourages sustained recovery and overall well-being.

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Evergreen Recovery Centers, located in Mount Vernon, WA, provides expert substance use rehabilitation in a nurturing atmosphere specifically designed for adult men. This center features both long-term residential stays and around-the-clock programs aimed at helping individuals who have faced intimate partner or domestic abuse. Emphasizing methods such as 12-step facilitation, anger management, and short intervention techniques, the facility supports active duty military members and men in pursuit of recovery. Serving a diverse group that includes adults, seniors, and younger adults, Evergreen Recovery Centers commits to delivering exceptional care for individuals ready to start their path to sobriety and overall health.

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Evergreen Treatment Services, located in Renton, WA, delivers a full range of outpatient programs designed to meet the unique needs of individuals facing substance use challenges. Emphasizing techniques such as motivational interviewing, relapse prevention strategies, and counseling for substance use disorders, this center ensures high-quality support for adult men and women, as well as pregnant or postpartum patients and young adults. With a focus on outpatient therapies involving methadone, buprenorphine, and naltrexone, the center fosters a nurturing environment for recovery. Evergreen Treatment Services stands out as a reliable option for those in the Renton community seeking targeted and effective rehabilitation solutions.

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Everlast Recovery Center in Riverside, CA, provides thorough addiction recovery services for individuals and young adults. Their expertise lies in detox, substance abuse therapy, and dual diagnosis. This center offers extended residential stays, emphasizing 12-step guidance, emotional regulation techniques, and concise intervention strategies. They also have dedicated plans for active military personnel, adult men, and adult women. By offering distinct therapeutic paths for different genders and age ranges, Everlast Recovery Center guarantees personalized attention and assistance for every individual's specific requirements. Experience high-quality support and successful recovery at this respected establishment.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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