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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Florida Addiction and Recovery Ctr

Situated in Fort Lauderdale, FL, Florida Addiction and Recovery Ctr delivers extensive treatment services for those struggling with addiction, catering to both adults and young adults. The center offers detoxification services, treatment for substance use disorders, and options for transitional living, including halfway houses and sober residences. Emphasizing 12-step methodologies, anger management strategies, and brief intervention techniques, Florida Addiction and Recovery Ctr customizes its programs to align with the unique needs of each client. Additionally, specialized programs are available for active duty military members, as well as adult men and women. With provisions for outpatient and intensive outpatient treatment, the center is dedicated to providing high-quality care to those seeking to overcome addiction.

Flushing Hospital and Medical Center

Flushing Hospital and Medical Center in Flushing, NY, delivers specialized detox programs. Clients receive hospital-based inpatient detoxification within a secure and encouraging setting. The center addresses varied requirements with dedicated tracks for individuals facing dual mental health and addiction challenges, as well as for expectant and new mothers. Its treatment methodologies encompass 12-step support, emotional regulation skills, and concise intervention strategies, promoting holistic healing. Catering to male and female adults and young adults, the facility emphasizes personalized care plans tailored to each person's unique path. Flushing Hospital and Medical Center is dedicated to providing high-caliber services, assisting individuals in their recovery endeavors.

Focus Treatment Centers

Focus Treatment Centers, located in Chattanooga, TN, delivers a wide range of rehabilitation services targeted at adults and young adults facing challenges related to substance use and concurrent mental health issues. The facility offers different treatment options such as intensive outpatient programs, outpatient services, and partial hospitalization, all customized to meet the specific needs of each individual. Emphasizing approaches like 12-step facilitation, brief interventions, and cognitive behavioral therapy, this center is dedicated to providing evidence-based support. The inclusion of specialized programs for men, women, and individuals impacted by intimate partner violence further demonstrates the center's commitment to addressing diverse requirements. With a strong focus on high-quality and personalized care, Focus Treatment Centers is dedicated to assisting clients throughout their recovery journey.

Focused Addiction Recovery

Focused Addiction Recovery in Wallace, NC, specializes in delivering targeted treatment for substance use disorders through a range of programs including intensive outpatient, outpatient, and day treatment. The center emphasizes personalized care, incorporating techniques such as 12-step facilitation, anger management, and brief interventions. It also features specific programs designed for active military personnel, men, and women, addressing a variety of needs. The facility serves both adults and young adults of any gender, guaranteeing customized support for every person. Focused Addiction Recovery's dedication to high-quality care and inclusive program offerings distinguishes it as a reliable choice for individuals exploring effective addiction recovery solutions.

Fond du Lac Human Services

Fond du Lac Human Services, located in Minneapolis, MN, is dedicated to providing extensive addiction treatment solutions for adults and adolescents grappling with substance abuse and co-occurring psychological health issues. Emphasizing relapse prevention, the facility offers robust intensive outpatient, outpatient, and standard outpatient recovery programs. Distinctive services include virtual therapy sessions and targeted programs for adult men, adult women, and survivors of domestic abuse. Catering to both male and female individuals, this center ensures high-quality support customized to the varied requirements of those pursuing sobriety within a nurturing setting.

Florence Crittenton Home and Services

Florence Crittenton Home and Services, situated in Helena, MT, delivers a full spectrum of care for addiction. The center offers detox, substance abuse therapy, and housing solutions like halfway houses and sober living environments. Clients can access long-term residential, outpatient, and standard outpatient programs, serving adults and seniors of all genders. Specific services are provided for expectant and new mothers. Employing methods like 12-step encouragement, concise intervention strategies, and reward-based motivation, the facility is dedicated to tailoring support for every individual's path to recovery.

Flint Odyssey House Inc

Flint Odyssey House Inc, situated in Flint, MI, delivers a full spectrum of care for individuals battling substance dependence. This establishment provides detox services, comprehensive addiction therapy, temporary housing, and supportive sober living environments. Their treatment modalities encompass extended residential stays, day programs, and standard outpatient services, serving both adults and adolescents. Employing therapeutic strategies such as anger resolution, focused interventions, and cognitive restructuring, the center is particularly adept at supporting those affected by domestic or partner abuse. Individualized programs are developed for adult males and females, offering customized support throughout their recovery journey. Count on Flint Odyssey House Inc for effective and compassionate addiction recovery solutions.

Fontainebleau Treatment Center

Fontainebleau Treatment Center, located in Mandeville, Louisiana, specializes in comprehensive treatment for substance abuse in both adults and young adults, particularly those grappling with concurrent mental health disorders. The center offers both residential and short-term residential options, featuring tailored programs that include anger management, brief interventions, and cognitive behavioral therapy. Fontainebleau serves both men and women, aiming to address the needs of clients who are involved in the criminal justice system. This facility is committed to providing exceptional, gender-responsive care that caters to the distinct requirements of every individual. If you're looking for effective support in a nurturing setting, Fontainebleau Treatment Center is devoted to helping you navigate your journey to recovery.

Focus Program Inc
Hamtramck, MI

Focus Program Inc. in Hamtramck, Michigan, delivers extensive addiction recovery support for all ages. They offer hospital-based inpatient detox and care for substance use disorders, alongside treatment for co-occurring mental health issues. Specialized tracks are available for active military personnel, teenagers, and adult males. Employing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center provides personalized support. Catering to a broad spectrum of ages and genders, including older adults and young adults, Focus Program Inc. utilizes effective, research-backed therapies to guide individuals toward sustained sobriety.

Florence Treatment Specialists

Situated in Florence, SC, Florence Treatment Specialists provides extensive outpatient services for individuals struggling with substance use. The center focuses on outpatient therapies involving methadone, buprenorphine, or naltrexone, emphasizing brief interventions, motivational interviewing, and techniques for preventing relapse. This facility offers specialized programs for adult males and females, in addition to support for clients who have faced intimate partner or domestic violence. By adopting a gender-sensitive approach and personalizing care, Florence Treatment Specialists delivers exceptional treatment to those pursuing recovery from substance use disorders within a compassionate and welcoming setting.

Florida Parishes Human Servs Authority

Located in Bogalusa, LA, Florida Parishes Human Servs Authority provides outpatient services for individuals dealing with substance use disorders, including both adults and children who also face mental health challenges. The center is known for its expertise in anger management techniques, short-term interventions, and cognitive behavioral therapy practices. Tailored programs are available for adult men and women, along with specialized support for those who have experienced domestic violence. This facility offers quality care in an inviting atmosphere, focusing on personalized treatment strategies to support adults and seniors of all backgrounds in their journey towards sustainable recovery.

Florida Parishes Human Servs Authority

Florida Parishes Human Servs Authority, located in Hammond, LA, provides a wide array of outpatient services aimed at adults and seniors struggling with substance use disorders and concurrent mental health issues. The center facilitates detoxification processes, along with treatment for substance dependence and tailored support for those with a history of trauma. Treatment methodologies encompass brief interventions, cognitive behavioral strategies, and motivational interviewing techniques. Emphasizing outpatient detox and administering methadone, buprenorphine, or naltrexone, this facility is designed to assist both men and women in finding individualized, research-supported care in a nurturing setting.

Floyd Behavioral Health

Floyd Behavioral Health, located in Rome, GA, provides an extensive selection of evidence-backed treatment options for both adults and young adults facing substance use challenges and accompanying mental health issues. Emphasizing approaches such as 12-step support, anger management techniques, and brief intervention strategies, this center focuses on addressing the unique needs of individuals with multifaceted problems. The facility offers inpatient detoxification and treatment services suitable for all genders, promoting a secure and nurturing atmosphere for recovery. Clients receive tailored treatment strategies and are supported by a diverse team of professionals committed to offering exceptional and empathetic care.

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Jacksonville Recovery Haven in Jacksonville, FL, provides varied therapeutic avenues for individuals struggling with addiction and co-occurring mental health challenges, serving both youth and adults. Their services encompass intensive outpatient care, day treatment programs, and partial hospitalization options. Employing methodologies such as 12-step support and emotional regulation techniques, the facility supports adults, older adults, and specific groups including LGBTQ+ clients. Committed to high standards of treatment and personalized strategies like motivational interviewing, this establishment fosters a nurturing setting for healing. Focusing on the treatment of adult males, teenagers, and LGBTQ+ individuals, this center delivers complete care for a broad spectrum of patients.

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Located in Denham Springs, LA, Florida Parishes Human Servs Authority provides a wide array of treatment options for substance use and co-occurring mental health issues, catering to both adults and children. The center offers various programs, such as intensive outpatient services, outpatient therapy, and methadone/buprenorphine solutions. Utilizing evidence-based therapies including cognitive behavioral therapy and anger management techniques, the facility also features specialized programs that serve active duty military personnel, adolescents, and adult men. Services are designed to accommodate adults and seniors of all gender identities, ensuring that Florida Parishes Human Servs Authority delivers personalized and effective rehabilitation care tailored to the unique needs of each individual.

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Florida Parishes Human Servs Authority, located in Mandeville, LA, specializes in outpatient services for individuals dealing with substance abuse and co-occurring mental health issues, catering to both adults and children. The center emphasizes various therapeutic interventions, including anger management, cognitive behavioral therapy, and trauma-informed practices, ensuring personalized care through programs designed for men, women, and individuals with trauma histories. This facility accommodates adults and seniors across the gender spectrum, providing outpatient options such as methadone/buprenorphine or naltrexone treatments, along with standard outpatient services. With a dedication to high-quality, evidence-based care, Florida Parishes Human Servs Authority offers extensive support to those striving to conquer addiction and mental health obstacles.

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Florida Parishes Human Servs Authority, located in Slidell, LA, delivers comprehensive treatment services for individuals of all ages facing substance use disorders and co-occurring mental health conditions. Their offerings include intensive outpatient, standard outpatient, and medication-assisted programs. Utilizing proven therapeutic methods such as 12-step facilitation, cognitive behavioral therapy, and anger management, the center addresses a wide range of client needs. Specialized support is available for those with a history of trauma and individuals navigating the criminal justice system. Serving both adult and child populations, Florida Parishes Human Servs Authority is dedicated to providing personalized, high-quality care that promotes complete well-being and sustained recovery.

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Focused Family Service in Phoenix, AZ, provides a complete suite of therapeutic interventions for those facing addiction and co-occurring mental health challenges. The facility offers intensive outpatient, outpatient, and day treatment programs, utilizing methods like anger management, brief intervention, and cognitive behavioral therapy. Dedicated programs for active duty military, adolescents, adult men, and seniors ensure tailored support across various demographics. Focused Family Service is recognized for its individualized approach and dedication to fostering sustained recovery.

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Fond du Lac Human Services, situated in Cloquet, MN, provides extensive treatment for substance use issues affecting both adults and young adults. The center is adept at addressing co-occurring disorders among adults, alongside serious mental health conditions, while also supporting children with significant emotional challenges. Treatment modalities include intensive outpatient care, long-term residential services, and various outpatient programs, employing diverse strategies like 12-step guidance, anger management techniques, and brief intervention therapies. The center features tailored programs specifically for adult males, adult females, and those who have faced intimate partner or domestic violence. Fond du Lac Human Services is dedicated to offering comprehensive and compassionate care to all individuals on their path to recovery.

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Situated in Duluth, Minnesota, Fond du Lac Human Services provides a wide range of rehabilitation options tailored for both adults and young adults. The center emphasizes treatment for substance use disorders and associated mental health issues, offering various levels of care including intensive outpatient, outpatient, and standard outpatient programs. With an approach that includes 12-step support, anger management strategies, and short-term intervention techniques, the facility serves individuals grappling with significant emotional and psychological challenges. Specialized programs are designed for adult men and women, as well as for those who have faced intimate partner violence. This center is dedicated to delivering high-quality care to all clients, standing as a crucial resource for those in need of compassionate and effective recovery services.

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Monticello, KY

Foothills Academy Inc, located in Monticello, KY, specializes in providing targeted substance use treatment for adults and seniors dealing with significant mental health challenges or emotional issues. The facility offers a range of services, including intensive outpatient programs, standard outpatient care, and treatments involving methadone, buprenorphine, or naltrexone. Their therapeutic approach includes 12-step support, brief interventions, and cognitive behavioral strategies, all tailored to address personal needs. With a strong focus on customized care, Foothills Academy Inc accommodates both male and female clients. The center is recognized for its extensive programs and high-quality, personalized treatment options, making it a leading choice for individuals seeking effective rehabilitation in the area.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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