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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Genesis Center of Winder LLC

Situated in Winder, GA, Genesis Center of Winder LLC provides an extensive array of outpatient rehabilitation options. The center emphasizes detoxification and treatment for substance use disorders, utilizing evidence-based methods like 12-step support, anger management techniques, and brief interventions. Tailored programs are designed specifically for active military members as well as adults, both men and women. Catering to a diverse group of adults and young adults, the facility offers customized care for each gender. With a commitment to high-quality care and individualized treatment strategies, Genesis Center of Winder LLC is focused on helping individuals navigate their path to recovery from addiction.

Genesis Healthcare System

Genesis Healthcare System, located in Zanesville, OH, provides an extensive array of services aimed at individuals, both adults and children, grappling with significant mental health issues and substance use disorders. The center features tailored programs designed for teenagers and those presenting with both addiction and mental health conditions. Treatment options available include intensive outpatient and standard outpatient programs, along with therapies utilizing methadone, buprenorphine, or naltrexone. By employing proven methods such as cognitive behavioral therapy and 12-step facilitation, Genesis Healthcare System effectively supports both male and female clients, ensuring high-quality care for adults and seniors in their journey towards recovery from addiction and associated mental health concerns.

Genesis Counseling of the Rockies LLC

Genesis Counseling of the Rockies LLC, located in Littleton, CO, provides comprehensive outpatient care for individuals battling substance use disorders. Their programs are designed for adults and young adults, incorporating evidence-based methods such as 12-step facilitation, anger management strategies, and brief intervention techniques. The center is dedicated to serving active duty military members, adult men, and women, ensuring that each client receives personalized attention. Genesis Counseling of the Rockies LLC is committed to fostering a path to sustained sobriety and overall wellness through customized treatment approaches.

Gaudenzia Inc

At Gaudenzia Inc in Erie, PA, we are dedicated to providing effective, research-backed therapeutic interventions for individuals struggling with substance use disorders and concurrent serious mental health challenges, as well as emotional difficulties in youth. Our offerings include intensive, regular, and standard outpatient care, drawing upon proven methods such as cognitive behavioral therapy, contingency management, and the Matrix Model. Gaudenzia Inc emphasizes personalized treatment plans for adults and young people of any gender, ensuring that each person receives high-quality, gender-affirming care specifically designed for their individual recovery path.

Gaudenzia Inc

Situated in Erie, PA, Gaudenzia Inc provides exceptional rehabilitation services tailored for women and older adults. With an emphasis on treating substance abuse and co-occurring mental health issues, the facility offers extended residential programs that incorporate 12-step methodologies, brief interventions, and cognitive behavioral approaches. This center is distinguished by its targeted initiatives for adult women, those who have faced sexual trauma or abuse, and young adults dealing with significant emotional difficulties. Gaudenzia Inc fosters a nurturing and secure atmosphere for those in need of thorough and individualized support to tackle addiction and mental health obstacles.

Gaudenzia Inc
Bristol, PA

Gaudenzia Inc in Bristol, PA, serves those in need of extensive addiction recovery solutions through a variety of targeted services. The center features residential detox services alongside multiple residential treatment options designed for adults and young adults dealing with substance use issues and concurrent mental health conditions. Utilizing approaches such as 12-step programs, brief interventions, and cognitive behavioral therapy, the facility delivers research-backed treatment. Special programs are available for adult men and women, as well as for individuals who have suffered from intimate partner or domestic violence. Gaudenzia Inc in Bristol prioritizes high-quality care for all clients, fostering a nurturing atmosphere conducive to healing.

Gavin Foundation

The Gavin Foundation, situated in Boston, MA, specializes in a wide array of treatment services for substance use disorders, serving both adults and youth. This facility offers various levels of care, including intensive and standard outpatient programs, as well as medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, anger management, and short intervention techniques, the center addresses the needs of those facing both addiction and significant mental health challenges. There are dedicated services for both men and women to provide customized support for each group. The Gavin Foundation is committed to delivering effective, gender-responsive treatment to aid individuals in their recovery journey.

Genesee Council On Alc/Subst Abuse

Genesee Council On Alc/Subst Abuse, located in Batavia, NY, delivers outpatient services for individuals facing substance use challenges. They provide specialized support for adults managing co-occurring serious mental health disorders. Their treatment approaches include anger management, cognitive behavioral therapy, and brief intervention strategies. The center is committed to personalized care, offering distinct programs for adolescents, adult men, and women. Their services extend to adults, children and adolescents, and seniors, with gender-specific options available. The facility also offers outpatient treatment using methadone, buprenorphine, or naltrexone, alongside general outpatient care, to support comprehensive recovery journeys.

Gaudenzia Inc
Philadelphia, PA

Situated in Philadelphia, PA, Gaudenzia Inc specializes in extended residential care and transitional living arrangements for women facing challenges related to substance use disorders. This center features tailored programs for those who have undergone experiences of intimate partner violence, domestic violence, or sexual assault. Emphasizing a 12-step methodology along with anger management and short intervention strategies, Gaudenzia Inc is committed to providing personalized support for adult and senior women on their path to recovery within a nurturing setting. For anyone seeking effective addiction recovery solutions with a focus on women's needs, this center is devoted to guiding women towards sustained sobriety and holistic health.

Gaudenzia Inc

Gaudenzia Inc, situated in Erie, Pennsylvania, delivers extensive treatment options for adult men battling substance use issues within a nurturing and organized setting. The center offers various services, including long-term residential care, transitional housing, and halfway housing. Emphasizing methods such as 12-step programs, anger management, and brief intervention techniques, Gaudenzia Inc is dedicated to aiding individuals in their recovery path. Tailored specifically for adult males, this establishment serves adults, seniors, and young adults alike. With continuous support and an all-male environment, Gaudenzia Inc guarantees a secure and effective rehabilitation experience for those in need of assistance with addiction.

Genesis Detox of Brooklyn LLC

Genesis Detox of Brooklyn LLC, located in Brooklyn, NY, provides focused detoxification and substance use treatment services in a residential environment. This center is equipped to deliver round-the-clock care and emphasizes techniques such as 12-step facilitation, anger management, and brief interventions. Customized programs are designed for adult men and women, in addition to young adults. With a strong commitment to high-quality care, this facility caters to both male and female clients, ensuring that adults receive personalized treatment plans for thorough rehabilitation support. If you or someone you care about is seeking professional assistance for addiction, Genesis Detox of Brooklyn LLC is dedicated to aiding your recovery process.

Genesis DOB
Brooklyn, NY

Genesis DOB, located in Brooklyn, NY, provides outpatient detox services and treatment options for substance use for both adult men and women, with distinct programs designed for those involved in the criminal justice system. Emphasizing 12-step support, anger management strategies, and succinct intervention methods, this center serves both adults and young adults who are looking for effective treatment solutions. Genesis DOB delivers outpatient treatment options with methadone, buprenorphine, or naltrexone, ensuring thorough assistance for individuals pursuing recovery. By offering customized services tailored to various genders and age brackets, this facility is dedicated to delivering personalized care that addresses the unique needs of each client.

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West Chester, PA

Situated in West Chester, PA, Gaudenzia Inc provides an extensive array of substance abuse treatment options for both adults and young adults facing dual diagnosis issues. This center offers various programs, including long-term, short-term, and around-the-clock residential care, designed to meet individual requirements. Gaudenzia Inc features specialized tracks for adult men, adult women, and individuals impacted by intimate partner violence, ensuring each client receives tailored support. Their treatment methodologies incorporate evidence-based practices such as 12-step facilitation, anger management strategies, and brief intervention methods. Dedicated to delivering high-quality care, this facility accommodates both male and female participants in pursuit of successful recovery solutions.

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Sunbury, PA

Situated in Sunbury, PA, Gaudenzia Inc delivers exceptional care for substance use disorders with diverse methodologies such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. The center features intensive outpatient care, standard outpatient services, as well as outpatient treatments utilizing methadone, buprenorphine, or naltrexone. Gaudenzia Inc also offers specialized programs designed for adolescents, adult men, and adult women, catering to various age brackets and gender identities, including children and teens. This facility is recognized for its all-encompassing and individualized approach to addiction recovery, making it an excellent choice for those seeking help for themselves or loved ones.

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Pottsville, PA

Gaudenzia Inc, situated in Pottsville, PA, delivers extensive treatment options for substance use disorders. The center features intensive outpatient programs, outpatient services, and treatments utilizing methadone/buprenorphine or naltrexone. It focuses on methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Gaudenzia Inc offers specialized programs designed for adolescents, men, and women, catering to adults as well as children and teens of any gender. Patients can anticipate receiving high-quality care and assistance from a committed group of professionals, making this center a great option for those needing tailored and effective addiction recovery services.

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Lewisburg, PA

Gaudenzia Inc, situated in Lewisburg, PA, delivers thorough substance use rehabilitation for adult men and women. This center features intensive outpatient care, standard outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the facility is equipped to support individuals with a history of trauma. Gaudenzia Inc provides specialized programs for adults and young adults, with distinct options for male and female patients. Prioritizing high-quality, personalized recovery plans, this institution is committed to guiding individuals through addiction challenges toward sustained sobriety.

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Berwick, PA

Gaudenzia Inc, situated in Berwick, PA, provides comprehensive substance use disorder services, encompassing intensive outpatient, outpatient, and medication-assisted treatment options like methadone, buprenorphine, and naltrexone. The center employs evidence-based therapeutic modalities such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Gaudenzia Inc is dedicated to serving a broad spectrum of individuals, with specialized programs designed for adolescents, adult men, and adult women. Their commitment to delivering high-quality care extends to both adults and young individuals, distinguished by personalized recovery strategies and robust support systems.

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Philadelphia, PA

Gaudenzia Inc, situated in Philadelphia, PA, is a prominent addiction treatment provider dedicated to assisting adults and young adults in their recovery from substance use disorders. They provide a range of services, including intensive outpatient care, standard outpatient programs, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing scientifically supported therapeutic strategies like 12-step facilitation, cognitive behavioral therapy, and contingency management, Gaudenzia Inc prioritizes a personalized approach to healing. The center welcomes both male and female individuals, ensuring that all clients receive thorough support designed for their unique circumstances. Gaudenzia Inc distinguishes itself through its unwavering dedication to superior treatment and bespoke recovery plans, establishing it as a premier destination for effective addiction recovery.

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Lancaster, PA

Gaudenzia Inc, located in Lancaster, PA, delivers extensive long-term and around-the-clock residential care for adults battling substance use disorders. The facility's robust program integrates techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. Emphasizing the support of adult women, seniors, and young adults who have faced intimate partner violence, domestic abuse, or sexual assault, the center customizes its interventions to address individual challenges. Gaudenzia Inc in Lancaster is recognized for its empathetic approach and reliance on proven therapeutic strategies, positioning it as a premier option for individuals pursuing effective addiction recovery and assistance.

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Situated in Albion, NY, the Genesee/Orleans Council on Alc delivers exceptional addiction treatment services for adults and older individuals. This center provides an array of outpatient options, including treatments with methadone, buprenorphine, or naltrexone, as well as standard outpatient programs. Techniques employed here encompass anger management, brief interventions, and cognitive behavioral therapy. The facility offers dedicated programs for different demographics, including adolescents and specific groups for adult men and women, ensuring personalized support for everyone. With its commitment to high-quality care and comprehensive rehabilitation strategies, the center serves as a vital support system for those in need of effective recovery solutions.

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Bloomsburg, PA

Genesis House Inc, situated in Bloomsburg, PA, provides a range of extensive treatment options for substance use aimed at adults, young adults, and teenagers. The center features intensive outpatient programs, standard outpatient treatment, and partial hospitalization services. Emphasizing methods such as 12-step support, anger management, and short intervention strategies, Genesis House Inc customizes its offerings to address the specific requirements of men, women, and people of all genders. The facility's distinct programs cater to teens, adult men, and adult women, ensuring tailored care for every client. Genesis House Inc is committed to delivering high-quality, gender-responsive treatment to aid individuals on their recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)