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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Genesis House Inc
Harrisburg, PA

Genesis House Inc in Harrisburg, PA, delivers a wide range of comprehensive treatment services for individuals striving for recovery from substance use disorders. The facility features various options, including intensive outpatient programs, traditional outpatient services, and partial hospitalization or day treatment programs. Emphasizing techniques such as 12-step facilitation, anger management, and brief intervention strategies, Genesis House Inc customizes its treatment plans to cater to the unique needs of adolescents, adult men, and adult women. Catering to a diverse clientele that includes adults, children and adolescents, as well as young adults of all genders, the center is committed to providing high-quality care and personalized support to guide clients toward sustainable recovery. Those seeking addiction treatment for themselves or a loved one will find a compassionate and effective journey towards healing at this center.

Glenbeigh Hosp and Outpatient Center

Glenbeigh in Rock Creek, OH, delivers extensive addiction recovery support. This facility provides inpatient medical detox, comprehensive treatment, and supportive transitional living options. Their approach incorporates 12-step principles, anger management techniques, and brief intervention strategies, serving adult men, women, and seniors. Glenbeigh Hosp and Outpatient Center accommodates both male and female individuals, focusing on adults and young adults. Renowned for its high standard of care and individualized recovery plans, Glenbeigh Hosp and Outpatient Center stands out as a premier option for effective and empathetic addiction care in the Rock Creek region.

Gloria Detox and Rehab Center

Gloria Detox and Rehab Center, situated in Van Nuys, CA, delivers extensive addiction recovery solutions for individuals of all ages. Their core expertise lies in extended residential stays, round-the-clock supervised detoxification, and continuous residential support. Utilizing proven therapeutic methods like 12-step integration, emotional regulation techniques, and cognitive behavioral therapy, the center addresses dual diagnoses, encompassing substance abuse alongside significant mental health challenges, including childhood emotional issues. Gloria Detox and Rehab Center dedicates itself to personalized treatment plans, serving adult men, adult women, and individuals with multifaceted requirements. Their dedication to customized support and targeted interventions positions them as a premier destination for superior addiction treatment.

Golden Peak Recovery

Nestled in Denver, Colorado, Golden Peak Recovery delivers extensive treatment options for those facing addiction and coinciding mental health challenges. Adults and young adults can access long-term residential stays, detox services, and round-the-clock support. The center employs personalized strategies including 12-step program guidance, strategies for managing anger, and brief intervention techniques to meet varied client requirements. Specialized care is provided for individuals with trauma histories, those with dual diagnoses, and people managing pain alongside substance use. Golden Peak Recovery is committed to providing excellent care to all clients, regardless of gender, as they embark on their path to healing.

Golden Road Recovery LLC

Golden Road Recovery LLC, located in Chatsworth, CA, provides a range of expert care for those facing addiction and co-occurring mental health challenges. The facility offers inpatient detox, continuous residential support, and shorter-term inpatient options for adults and young adults. Emphasizing personalized recovery, they incorporate 12-step support, emotional regulation techniques, and short-term counseling. Residents find a nurturing setting designed for their unique journeys. Golden Road Recovery LLC welcomes both men and women, delivering a complete and welcoming path to sobriety for everyone pursuing lasting recovery.

Glass House Recovery LLC
Ellicott City, MD

Glass House Recovery LLC, located in Ellicott City, MD, provides a wide array of treatment services for individuals grappling with substance use and concurrent severe mental health disorders. The center offers various levels of care, including intensive outpatient, outpatient, and day treatment programs. Their therapeutic approach combines 12-step methodologies, cognitive behavioral therapy, and brief intervention techniques. Glass House Recovery LLC features specialized programs designed for adult men, adult women, and individuals who have faced traumatic experiences. With a strong emphasis on supporting adults and young adults of all genders, the center develops customized treatment strategies within a nurturing environment. This facility is committed to delivering quality care and personalized assistance to those on their journey to recovery from addiction and mental health issues.

Gilmore Community Healing Centers

Situated in Kalamazoo, MI, Gilmore Community Healing Centers deliver a wide array of services for those struggling with addiction. The facility is dedicated to detoxification and treatment for substance use, as well as supporting individuals facing dual mental health challenges. It features various programs including long-term residential care, detoxification, and 24-hour residential support, accommodating both adult and young adult populations in their journey to recovery. By incorporating methods such as 12-step facilitation, anger management, and brief interventions, Gilmore Community Healing Centers also offer unique programs designed for pregnant or postpartum women and those dealing with concurrent pain and substance use issues. Committed to high-quality service, this center provides customized treatment plans for clients of all genders.

Gibson Recovery Center Inc
Cape Girardeau, MO

Gibson Recovery Center Inc, situated in Cape Girardeau, MO, presents an extensive array of services aimed at treating addiction for both adults and young adults. This facility offers detoxification, intensive outpatient programs, and day outpatient treatment, emphasizing counseling for substance use disorders, trauma therapy, and telehealth alternatives. Specialized programs are available for adult males, individuals facing both mental health issues and substance use disorders, and those involved in the legal system. Dedicated to providing high-quality care and personalized treatment strategies, the center serves both male and female clients in their journey toward recovery from addiction and co-occurring challenges.

Gibson Recovery Center Inc

Gibson Recovery Center Inc, situated in Marble Hill, MO, delivers extensive treatment for substance use disorders to both adults and young adults. The center features outpatient services that encompass methadone/buprenorphine or naltrexone treatment. With an emphasis on counseling for substance use disorders, trauma-informed therapy, and telehealth services, it effectively supports clients dealing with concurrent mental health challenges. Specialized programs are tailored for men and women. Gibson Recovery Center Inc is committed to providing high-quality care to those pursuing recovery from substance use and related mental health issues, utilizing diverse therapeutic methods to assist both male and female clients.

Gibson Recovery Center Inc
Cape Girardeau, MO

Gibson Recovery Center Inc, located in Cape Girardeau, MO, specializes in providing tailored substance abuse treatment for adult females who are also facing mental health challenges. This center offers a range of services including intensive outpatient programs, outpatient day treatments, and counseling focused on trauma. It serves a diverse clientele that includes adults, seniors, and young adults, particularly prioritizing those with dual diagnoses and individuals connected with the criminal justice system. With a strong commitment to female-focused support, Gibson Recovery Center Inc ensures that rehabilitation services are customized to meet the specific requirements of each individual.

Genesis Project 1 Inc

Genesis Project 1 Inc., located in Charlotte, NC, delivers complete addiction recovery services and tailored support for those facing dual diagnoses of substance use disorders and mental health challenges. Their offerings include intensive outpatient care, general outpatient programs, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing proven methods like 12-step facilitation, anger management, and brief intervention, the center crafts personalized recovery plans. The program extends specialized support to young people and caters to adults and older adults of all genders, committed to providing excellent care for a successful recovery journey.

Gilead Community Services Inc

Gilead Community Services Inc, situated in Middletown, CT, delivers a wide range of outpatient services addressing substance use and concurrent mental health issues for both adults and children. This center features specialized programs designed for active military personnel, veterans, and individuals facing dual diagnoses. Employing proven methods such as cognitive behavioral therapy and motivational interviewing, the facility serves both men and women, including young adults. With an emphasis on anger management and customized outpatient treatments including methadone and buprenorphine therapy, Gilead Community Services Inc is dedicated to providing exceptional, individualized care for those seeking recovery.

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Williamsport, PA

Genesis House Inc, located in Williamsport, PA, provides targeted treatment for individuals aiming to overcome substance use disorders. This center offers various options, including intensive outpatient programs, standard outpatient services, and partial hospitalization. Emphasizing 12-step methodologies, anger management techniques, and brief intervention strategies, the center serves a diverse clientele, including adolescents and adult men and women. Catering to the needs of adults, children, and young adults, Genesis House Inc features gender-responsive programming for both males and females. The center's dedication to high-quality care and personalized treatment plans establishes it as an important resource for those pursuing comprehensive recovery solutions in the Williamsport region.

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Genesis Project North, situated in Henderson, NC, delivers focused substance use treatment for both adults and children facing concurrent severe mental health challenges. This center emphasizes personalized care and offers a variety of programs including intensive outpatient, outpatient, and standard outpatient treatments. By implementing methods like 12-step facilitation, anger management, and brief interventions, the facility serves clients of all genders and ages. What sets Genesis Project North apart is its customized therapeutic strategies and dedication to delivering exceptional care that aids individuals in their recovery process.

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Georgetown, SC

Georgetown County, situated in Georgetown, SC, delivers targeted substance abuse treatment services for both adults and teenagers. The center features a variety of programs, including intensive outpatient care, outpatient services, and treatment options utilizing methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, the center customizes its methodologies to fit the unique requirements of each patient. Georgetown County is particularly noted for its focused adolescent programs, along with gender-specific treatment options for male and female clients. Patients can anticipate exceptional care in a nurturing atmosphere aimed at promoting enduring recovery.

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Situated in Cape Girardeau, MO, the Gibson Center for Behavioral Change specializes in treating substance use issues specifically for adult women. This center offers a variety of programs including intensive outpatient, outpatient, and day treatment options for those dealing with both mental health challenges and substance use disorders. Emphasizing trauma-informed care, the facility supports adults and young adults who are experiencing significant emotional difficulties. Additionally, it serves clients from the criminal justice system seeking assistance with rehabilitation. The Gibson Center for Behavioral Change is committed to delivering effective care and support for individuals pursuing substantial behavioral transformation.

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Gibson Recovery Center Inc, situated in Perryville, MO, delivers extensive treatment options for substance use disorders aimed at both adults and young adults. The center features an array of services, including intensive outpatient care, outpatient services, and treatments utilizing methadone and buprenorphine, specifically addressing individuals who also face mental health challenges. With a focus on counseling for substance use issues and therapies for trauma, the center also embraces telehealth options. Gibson Recovery Center Inc provides customized programs for adult men and women, as well as those with dual diagnoses, ensuring high-quality support for patients on their path to recovery from addiction.

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Gibson Recovery Center Inc, situated in Sikeston, MO, is a dedicated facility for adults navigating substance misuse alongside significant mental health challenges. They offer a spectrum of services including intensive outpatient programs, general outpatient care, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their approach emphasizes substance use disorder counseling, trauma-informed interventions, and the convenience of telehealth. Gibson Recovery Center Inc serves adult men and women, with a particular specialization in dual diagnosis care. They provide customized rehabilitation plans for both adult and young adult populations, ensuring inclusive and effective recovery support for all genders.

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Situated in Chester, CT, Gilead Community Services Inc delivers extensive treatment for substance use and specialized support for individuals facing co-occurring mental health issues, catering to both adults and children. The center offers outpatient services, day treatment options, and standard outpatient care, employing evidence-based methodologies like cognitive behavioral therapy and motivational interviewing. Gilead provides customized programs aimed at active military personnel, veterans, and those with dual diagnoses, accommodating adults and young adults of any gender. The center is recognized for its high-quality care and dedication to meeting the distinct needs of each person on their recovery journey.

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Gold Bridge Treatment Center in Louisburg, KS, delivers thorough addiction recovery services within a nurturing setting. This institution features extended residential stays, round-the-clock residential care, and shorter residential options designed for adult males and females, as well as young adults. Emphasizing techniques like anger resolution, cognitive-behavioral approaches, and motivational dialogue, the center supports individuals facing trauma, co-occurring psychological and addiction issues, and pain with substance dependency. Gold Bridge Treatment Center is committed to delivering excellent care and tailored recovery strategies to guide individuals toward lasting sobriety.

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San Diego, CA

Situated in San Diego, California, Golden Hill House I is a premier rehabilitation facility that specializes in treating substance use disorders alongside serious mental health conditions in adults, as well as addressing significant emotional challenges in children. The center offers long-term residential programs and round-the-clock support, implementing evidence-based techniques, including 12-step programs, anger management strategies, and brief therapeutic interventions. With a particular emphasis on supporting adult women who have faced intimate partner violence, domestic abuse, or sexual trauma, Golden Hill House I serves a diverse population including adults, seniors, and young adults. Its dedication to delivering high-quality care in a supportive environment specifically tailored for women distinguishes it as an exceptional option for individuals pursuing extensive rehabilitation services.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)