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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Gulf Breeze Recovery
Gulf Breeze, FL

Gulf Breeze Recovery, situated in Gulf Breeze, FL, provides an extensive array of rehabilitation services aimed at adults and adolescents facing challenges with substance abuse and concurrent mental health issues. The center features intensive outpatient programs, long-term residential care, and general outpatient services. Emphasizing strategies like anger management, motivational interviewing, and relapse prevention, Gulf Breeze Recovery customizes treatment plans to meet the unique needs of each individual. Additionally, specialized programs are offered for active duty military personnel, as well as separate tracks for adult men and women. This facility is designed to accommodate both genders, fostering a compassionate and welcoming atmosphere for everyone in pursuit of quality treatment.

Gundersen Lutheran Medical Ctr Inc

Gundersen Lutheran Medical Ctr Inc, situated in La Crosse, WI, delivers targeted rehabilitation for those facing substance use issues alongside mental health challenges. Their comprehensive services encompass intensive outpatient, outpatient, and standard outpatient treatment plans. The center employs proven methods like cognitive behavioral therapy, anger management techniques, and contingency management/motivational incentives. Emphasizing care for individuals with dual diagnoses, Gundersen Lutheran Medical Ctr Inc supports adults and seniors of all genders, offering personalized treatment to meet diverse requirements.

HOPE Community Services Inc

HOPE Community Services Inc, located in Oklahoma City, OK, is dedicated to providing thorough care for individuals struggling with substance abuse, particularly those also managing serious mental health concerns or supporting children with emotional challenges. They offer diverse outpatient options, including intensive programs and targeted support for active military personnel, young people, and adult men. Utilizing methods such as 12-step guidance, anger control techniques, and brief support strategies, the center serves a broad demographic of adults and seniors. HOPE Community Services Inc is committed to delivering personalized, high-quality treatment in a nurturing setting, establishing itself as a key provider of effective recovery services.

HANAC Inc
Astoria, NY

HANAC Inc, situated in Astoria, NY, delivers focused addiction recovery services designed for adults and adolescents. The facility offers various outpatient options such as medication-assisted treatment (methadone, buprenorphine, naltrexone), general outpatient care, and short-term intervention. Utilizing approaches like cognitive behavioral therapy and motivational incentives, HANAC Inc personalizes its offerings. They also feature specialized programs for active military personnel, adult men, and adult women. Committed to providing excellent care and a supportive atmosphere, HANAC Inc welcomes all individuals on their path to recovery.

HMR Counseling and Behavioral Services

HMR Counseling and Behavioral Services in Okemos, MI, provides comprehensive outpatient programs addressing substance use and co-occurring mental health challenges for adults, as well as emotional disturbances in children. Their therapeutic approach integrates 12-step facilitation, anger management techniques, and brief intervention strategies. They offer specialized support for active duty military members, adolescents, adult men, and seniors of all genders, creating a supportive and respectful atmosphere for everyone. HMR Counseling and Behavioral Services is committed to guiding individuals toward lasting recovery through personalized care.

HRI Hospital
Brookline, MA

Nestled in Brookline, MA, HRI Hospital stands as a premier institution dedicated to providing extensive addiction recovery solutions for adults and young adults. This facility offers inpatient hospital detoxification and therapeutic interventions for individuals grappling with substance use disorders and co-occurring mental health conditions. Recognizing diverse needs, HRI Hospital has developed tailored programs for adult men, adult women, and survivors of intimate partner violence, guaranteeing that each client receives personalized attention. Employing proven methodologies such as cognitive behavioral therapy and anger management, the center is committed to delivering superior, individualized care aimed at fostering sustained sobriety. For those in search of expert addiction treatment within a hospital environment, HRI Hospital is a reliable and esteemed option.

HALO Educational Systems

HALO Educational Systems, located in Lebanon, NH, provides outpatient services for adults grappling with substance use issues alongside serious mental health challenges, as well as for children facing significant emotional difficulties. This center offers targeted programs designed for military personnel, youths, and adult males. Their treatment methodologies encompass 12-step programs, anger management strategies, and short-term interventions. HALO Educational Systems serves both men and women, offering outpatient options involving methadone/buprenorphine and naltrexone therapies. Emphasizing high-quality care, the center adapts its programs to meet the unique needs of different genders and age groups, ensuring comprehensive assistance for those on the path to recovery.

HALO Educational Systems

HALO Educational Systems, located in Canaan, NH, provides thorough treatment for adults dealing with substance use issues alongside serious mental health conditions, as well as children facing significant emotional challenges. Their offerings encompass a range of services including intensive outpatient treatment, standard outpatient care, and medication-assisted treatments with methadone/buprenorphine or naltrexone. Utilizing targeted strategies like 12-step programs, anger management, and brief interventions, this center supports active duty military members, teenagers, and adult males. HALO Educational Systems is dedicated to serving individuals of all genders among both adults and children/adolescents, delivering high-quality, personalized care aimed at fostering successful recovery journeys.

Guidance Center Inc
Flagstaff, AZ

Guidance Center Inc, situated in Flagstaff, AZ, delivers a wide array of services addressing substance use issues and concurrent mental health challenges. This facility is well-versed in detoxification, treatment for substance dependencies, and providing support to individuals facing severe mental health struggles. They offer hospital-based detox programs, intensive outpatient care, and round-the-clock inpatient services. The center employs various therapeutic methods, such as cognitive behavioral therapy, anger management techniques, and the Matrix Model, accommodating adults and elderly clients across the gender spectrum. Additionally, it features distinct programs for adolescents, those affected by intimate partner violence, and individuals with past experiences of sexual abuse, ensuring a nurturing atmosphere for recovery.

Guidance Center Inc
Flagstaff, AZ

Nestled in Flagstaff, AZ, The Guidance Center Inc. provides extensive support for adults and adolescents struggling with addiction and co-occurring mental health conditions. Their hospital inpatient services encompass detoxification and specialized interventions for survivors of domestic violence, sexual assault, and trauma. Utilizing approaches like anger management, cognitive behavioral therapy, and the Matrix Model, the center customizes treatment plans for each person. This facility offers a secure environment for individuals of all genders, dedicated to delivering exceptional care for those on their journey to recovery and well-being.

Guidance Center Inc
Flagstaff, AZ

Guidance Center Inc, situated in Flagstaff, AZ, is a dedicated facility providing extensive support for adults and young adults struggling with substance use disorders, particularly when accompanied by severe mental health conditions or emotional challenges. The center delivers a range of care options including extended stay residential, brief residential, and round-the-clock services. They employ proven therapeutic strategies like cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Guidance Center Inc has a particular expertise in assisting individuals who have endured trauma, domestic abuse, or sexual assault, and welcomes both men and women. Prioritizing high-quality treatment and individualized plans, Guidance Center Inc is a reliable option for those in search of effective recovery within a nurturing setting.

Gulf Coast Addiction Medicine LLC

Gulf Coast Addiction Medicine LLC, situated in Panama City, FL, provides comprehensive care for individuals struggling with addiction. Their programs include intensive outpatient services, general outpatient support, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Therapeutic approaches employed by the center consist of 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, all aimed at fostering recovery. Gulf Coast Addiction Medicine LLC is committed to delivering personalized treatment plans for adult clients of any gender, striving to guide them toward sustained sobriety and overall well-being.

HAART
Oakland, CA

HAART in Oakland, CA, stands as a premier rehabilitation establishment, providing comprehensive outpatient programs for detoxification and substance use disorders. Their specialized services encompass brief intervention, cognitive behavioral therapy, and contingency management/motivational incentives. HAART serves a wide array of individuals, including active duty military, adult men, and adult women. Catering to adults and seniors regardless of gender, the center offers outpatient treatment with methadone, buprenorphine, or naltrexone. HAART delivers exceptional, personalized care, positioning it as a distinguished option for effective addiction recovery in the Oakland community.

HCMC Addiction Medicine Program

Situated in Minneapolis, MN, the HCMC Addiction Medicine Program provides outpatient care for adults and young adults dealing with substance use issues. The center specializes in methadone or buprenorphine as well as naltrexone treatment, employing various evidence-backed methods such as brief intervention, cognitive behavioral therapy, and the Matrix Model. Prioritizing tailored care, the program serves both male and female clients. HCMC's commitment to high-quality treatment and customized care plans positions it as an important option for individuals seeking thorough and effective addiction support.

HMHI Park City Behavioral Hlth Clinic

HMHI Park City Behavioral Hlth Clinic in Park City, UT, delivers thorough care for adults managing substance use disorders alongside significant mental health conditions. The clinic features robust outpatient services, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy and motivational interviewing, the facility supports adult men and women, older adults, and survivors of intimate partner violence. Through individualized treatment plans, HMHI Park City Behavioral Hlth Clinic is dedicated to providing exceptional support for individuals pursuing recovery from addiction and mental health struggles.

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The Guidance Center of Westchester in New Rochelle, NY, delivers extensive outpatient services for individuals of all ages struggling with substance abuse and associated mental health conditions. They offer tailored programs for men, women, and young adults, emphasizing approaches like cognitive behavioral therapy, anger management, and brief interventions. Patients can access personalized outpatient medication management, including methadone/buprenorphine and naltrexone. This facility is dedicated to providing high-quality, individualized care to support the recovery journey for everyone who seeks their assistance.

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El Dorado, AR

Situated in El Dorado, AR, the Guinn Clinic provides outpatient treatment for substance use, targeting both adults and young adults. This center specializes in addressing co-occurring serious mental health conditions alongside substance use issues in adults, and it also supports children facing significant emotional disturbances. The Guinn Clinic delivers customized care primarily focused on counseling for substance use disorders. Treatment modalities available include outpatient options with methadone/buprenorphine or naltrexone. Catering to a diverse clientele of both males and females, the center's commitment to individualized treatment ensures that care is adapted to match each person's unique situation, establishing it as an essential provider of thorough and tailored rehabilitation services.

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Gundersen Lutheran Medical Ctr Inc in Onalaska, WI, provides extensive support for adults and seniors facing challenges with addiction and co-occurring mental health issues. Their rehabilitation programs include intensive outpatient, day treatment, and flexible outpatient options, all customized to each person's unique requirements. Utilizing proven methods such as cognitive behavioral therapy and anger management, the center also employs contingency management techniques to foster sustained recovery. They are particularly adept at serving individuals with dual diagnoses and offer distinct care pathways for both male and female patients. Gundersen Lutheran Medical Ctr Inc dedicates itself to offering superior, individualized care to guide individuals toward a healthier life.

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Hayward, CA

Situated in Hayward, CA, HAART provides extensive outpatient detox and substance abuse treatment services. The center is known for its customized approaches, including cognitive behavioral therapy and motivational incentives, aimed at facilitating recovery. HAART caters specifically to active duty military members, adult males, and females. With a commitment to serving adult and elderly clients, this facility develops personalized treatment strategies for both genders. Prioritizing exceptional care, HAART is focused on enabling individuals to attain enduring recovery through proven methodologies and a nurturing atmosphere.

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In Mahwah, NJ, Hackensack Meridian Carrier Clinic is a facility dedicated to providing individualized care for those addressing substance use challenges. They offer a range of treatment levels, including intensive outpatient services, standard outpatient programs, and medication-assisted treatment employing methadone, buprenorphine, or naltrexone. The clinic's approach incorporates anger management, brief intervention strategies, and cognitive behavioral therapy, serving both adult men and women, as well as young adults. They also feature distinct programs for active duty military members. Hackensack Meridian Carrier Clinic is committed to offering effective support throughout the recovery process.

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Nestled in Belle Mead, NJ, Hackensack Meridian Carrier Clinic provides extensive detox and addiction recovery services. Their offerings include hospital-based inpatient detoxification, round-the-clock inpatient care, and robust outpatient treatment, all tailored for adults and young adults. The clinic emphasizes 12-step facilitation, anger management, and brief intervention strategies, serving active military, adult men, and women. Through gender-specific care and customized recovery paths, this establishment is dedicated to client welfare, delivering excellent support for individuals pursuing sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)