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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Healthcare Resource Centers

Healthcare Resource Centers located in New Bedford, MA, provides outpatient treatment options focused on substance use for both adults and young adults. This center addresses the needs of clients dealing with HIV or AIDS, as well as those experiencing co-occurring mental health and substance use issues, including pregnant and postpartum women. Various treatment methods are employed, such as anger management, brief interventions, and cognitive behavioral therapy. Committed to delivering high-quality care, the center offers outpatient services that include methadone/buprenorphine or naltrexone treatment along with standard outpatient support. Healthcare Resource Centers serves both male and female clients in a nurturing and inclusive setting aimed at aiding individuals on their journey to recovery from substance use disorders.

HealthRIGHT 360
Union City, CA

HealthRIGHT 360 located in Union City, CA, provides a wide range of substance use treatment options, including intensive outpatient, outpatient, and standard outpatient programs. Utilizing research-supported methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, this facility aims to address the unique needs of its clients. It serves adult men, adult women, and young adults, offering tailored programs suited to each demographic. With its emphasis on delivering high-quality care for adults and young adults of all genders, HealthRIGHT 360 is dedicated to helping individuals achieve sustainable recovery through compassionate and knowledgeable support.

HealthRIGHT 360
San Francisco, CA

HealthRIGHT 360 in San Francisco, CA, provides outpatient substance use disorder services for adult women, seniors, and young adults. This center focuses on regular outpatient care, employing proven methods like 12-step facilitation, anger management, and cognitive behavioral therapy. Their programs are designed for individuals with co-occurring mental health and substance use challenges, as well as those affected by trauma. HealthRIGHT 360 prioritizes personalized and comprehensive care, aiming for complete client recovery. For targeted addiction treatment in a nurturing setting, this facility offers complete solutions designed for your specific requirements.

HealthRIGHT 360
San Francisco, CA

HealthRIGHT 360 in San Francisco, California, provides extensive care for individuals struggling with addiction, operating as a long-term residential program solely for adult men. This center excels in managing dual diagnoses involving mental health and substance dependency, alongside trauma and anger concerns, utilizing proven methods like 12-step support and cognitive behavioral therapy. Their structured program is designed to support adults, older individuals, and younger adults in their journey toward recovery within a nurturing atmosphere. For those in search of a dedicated rehabilitation facility focused on male patients and personalized treatment strategies, HealthRIGHT 360 presents a fitting option.

HealthRIGHT 360
San Francisco, CA

HealthRIGHT 360, located in San Francisco, CA, provides extended residential stays and round-the-clock support for adult women facing challenges with substance dependence. This facility features dedicated services for individuals who have endured intimate partner violence, domestic abuse, and sexual trauma. Emphasizing 12-step principles, strategies for managing anger, and cognitive behavioral techniques, their approach is personalized to each client's unique journey. HealthRIGHT 360 is a resource for adult women and older adults in search of a secure and nurturing setting for their recovery process. Their all-encompassing methodology and targeted programs guarantee excellent care for those striving to heal from addiction and past traumas.

HealthRIGHT 360
San Francisco, CA

HealthRIGHT 360 in San Francisco, CA, delivers outpatient services for individuals grappling with substance use issues. This program is designed to support adult men and women, particularly those with a history of trauma. They utilize proven therapeutic strategies like 12-step integration, anger control techniques, and cognitive behavioral approaches. The center features distinct programs tailored for adult men, adult women, and individuals impacted by trauma, accommodating a variety of needs. Serving adults and young adults across all gender identities, HealthRIGHT 360 offers personalized care. Discover effective addiction recovery within a nurturing setting at this established treatment facility.

HealthWest
Muskegon, MI

HealthWest, located in Muskegon, MI, provides outpatient services for adults struggling with substance use issues, with a particular emphasis on those facing both substance use and significant mental health challenges, as well as emotional issues in children. The center prioritizes methods such as anger management, brief interventions, and cognitive behavioral therapy. It offers consistent outpatient treatment along with options for methadone, buprenorphine, or naltrexone. Specialized programs are created for adolescents and adult men and women. HealthWest caters to adults and seniors of all genders, delivering a thorough and personalized approach to rehabilitation, thereby ensuring superior care for individuals on their journey to recovery from substance use disorders and mental health difficulties.

Healthy Lives LLC
Halethorpe, MD

Healthy Lives LLC, situated in Halethorpe, MD, delivers thorough substance use care for individuals of all ages experiencing co-occurring serious mental health conditions. The facility features intensive outpatient, outpatient, and day treatment programs, integrating methods such as 12-step facilitation, anger management, and brief interventions. Tailored services are available for teens, adult men, and women, accommodating various demographics. Healthy Lives LLC emphasizes bespoke treatment strategies to foster healing and improved health. For those searching for impactful and customized addiction treatment, this center is committed to guiding you toward sustained sobriety and mental balance.

Healthy Living Residential Program

Nestled in Santa Clarita, CA, the Healthy Living Residential Program delivers extensive care for adults and young adults facing addiction challenges and co-occurring psychological conditions. This establishment emphasizes personalized care through its long-term residential stays, detox services, and round-the-clock residential options. Employing methods like 12-step integration, emotional regulation training, and concise intervention strategies, the center customizes healing plans to suit each individual's distinct requirements. Featuring distinct tracks for men and women, the Healthy Living Residential Program cultivates a nurturing and productive setting for those on the path to wellness.

Healthcare for the Homeless Houston

Healthcare for the Homeless Houston, located in Houston, TX, provides thorough addiction treatment via flexible outpatient services designed to meet each person's unique requirements. The center employs scientifically proven methods, including brief intervention, cognitive behavioral therapy, and motivational interviewing, to combat addiction effectively. Specific services are offered for adult men, adult women, and individuals affected by intimate partner or domestic violence. Serving adults and seniors of all genders, this establishment delivers excellent care within a nurturing setting. Individuals looking for tailored and empathetic addiction recovery support will discover significant assistance at Healthcare for the Homeless Houston.

Healthcare Resource Centers

Healthcare Resource Centers, situated in Westfield, MA, specializes in outpatient substance abuse recovery, employing proven methods such as cognitive behavioral therapy, motivational interviewing, and contingency management. The center features distinct programs tailored for active duty military members, adult males, and adult females. Catering to adults and young adults of all genders, they offer outpatient care involving methadone/buprenorphine or naltrexone, in addition to general outpatient services. Healthcare Resource Centers is dedicated to providing excellent, personalized treatment to individuals pursuing sobriety.

Healthy Paradigms LLC

Situated in Van Nuys, California, Healthy Paradigms LLC specializes in a wide range of addiction recovery services tailored for both adults and young adults. The center offers detox and various levels of substance use treatment, including intensive outpatient programs, outpatient services, and day treatment options. By employing scientifically-supported methods like 12-step programs, brief interventions, and cognitive behavioral therapy, the facility effectively supports adults grappling with both substance use and concurrent mental health issues. Healthy Paradigms LLC emphasizes personalized treatment, providing high-quality care to men and women striving for addiction recovery.

HealthWorks
Cheyenne, WY

HealthWorks, situated in Cheyenne, WY, delivers outpatient services for individuals battling substance use challenges. They also provide specialized support for adults experiencing co-occurring substance use and severe mental health issues, as well as children with significant emotional disturbances. This center features outpatient medication management, including methadone, buprenorphine, or naltrexone, alongside ongoing outpatient therapy. Their therapeutic methods encompass anger management, brief intervention, and cognitive behavioral therapy, all tailored to each individual's needs. HealthWorks is committed to offering exceptional, customized treatment for adult and senior clients, irrespective of gender, to foster lasting recovery.

HealthRIGHT 360
San Mateo, CA

HealthRIGHT 360, located in San Mateo, CA, provides focused substance use treatment through its long-term residential and round-the-clock residential programs. The facility employs various methods, including 12-step support, anger management, and cognitive behavioral therapy, designed for adult women, individuals who have faced trauma, seniors, and younger adults. With a strong commitment to women's issues, HealthRIGHT 360 offers personalized care that addresses specific needs. The center's dedication to quality and its distinctive programs establish it as a crucial resource for individuals in search of effective and compassionate recovery services.

HealthRIGHT 360
San Mateo, CA

Located in San Mateo, CA, HealthRIGHT 360 provides an extensive range of substance abuse rehabilitation options, including both long-term and around-the-clock residential programs. The center emphasizes 12-step support, anger management techniques, and cognitive behavioral therapy, specifically catering to adult women who have faced issues such as intimate partner violence, domestic abuse, and sexual trauma. By offering services to adults, seniors, and young adults, the facility uniquely concentrates on the needs of female clients, distinguishing it from other centers. HealthRIGHT 360 is committed to delivering high-quality, personalized care to foster enduring recovery for individuals battling addiction.

HealthRIGHT 360
Pomona, CA

HealthRIGHT 360 located in Pomona, California, provides extensive addiction recovery services specifically designed for adult women within a nurturing and secure atmosphere. The center offers long-term residential treatment options that encompass detox services, substance abuse therapy, and targeted attention for co-existing mental health challenges. Emphasizing a 12-step approach, anger management techniques, and short-term interventions, the facility supports individuals who have faced trauma, sexual assault, and significant emotional difficulties. HealthRIGHT 360 caters to a diverse clientele, including adults, seniors, and younger adults, ensuring quality care that addresses the distinct recovery needs of women battling addiction.

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Healthcare Resource Centers, located in Northampton, MA, provides a wide range of outpatient substance use treatment options, including methadone, buprenorphine, and naltrexone therapies. The center excels in various therapeutic techniques such as anger management, brief interventions, and cognitive behavioral therapy. With specific programs designed for adult men and women, as well as those who have encountered intimate or domestic violence, the facility offers personalized support for all genders, including young adults. Healthcare Resource Centers is committed to delivering high-quality care and utilizing evidence-based methods to assist individuals in their recovery from substance use disorders.

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Pomona, CA

HealthRIGHT 360 in Pomona, CA, delivers extensive addiction recovery through diverse outpatient programs designed for personalized care. Their offerings include intensive outpatient treatment, standard outpatient treatment, and general outpatient services. Emphasizing 12-step facilitation, anger management, and cognitive behavioral therapy, the facility promotes a complete recovery journey. HealthRIGHT 360 serves adolescents, adult men, and adult women, encompassing both young and adult populations. By providing gender-specific programs and support, the center is dedicated to high-quality treatment for individuals pursuing sobriety in Pomona.

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Pasadena, CA

HealthRIGHT 360 in Pasadena, CA delivers thorough addiction treatment for adults and adolescents dealing with co-occurring mental health concerns or emotional distress. Services include intensive outpatient, outpatient, and medication-assisted treatment (methadone/buprenorphine or naltrexone). The center employs proven methods such as cognitive behavioral therapy and community reinforcement with incentives. Tailored programs are available for adult men, women, and individuals affected by intimate partner or domestic abuse. Prioritizing personalized care, this establishment offers quality support for male and female individuals pursuing recovery from substance dependence and mental health issues.

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Oxnard, CA

HealthRIGHT 360 in Oxnard, California, provides extensive substance abuse treatment for adult women dedicated to sobriety. Their offerings include extended residential stays, detox services on-site, and continuous 24-hour supervision within a residential setting. This center is adept at addressing both addiction and co-occurring psychological issues, employing proven methods like 12-step program integration, emotional regulation techniques, and cognitive behavioral strategies. Recognizing the impact of past trauma, HealthRIGHT 360 serves a diverse age range, from older adults to young adults. Their distinct specialization in female-focused care highlights HealthRIGHT 360's commitment to providing exceptional and empathetic recovery support.

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Wheeling, WV

HealthWays Inc, located in Wheeling, WV, specializes in extensive treatment for substance use among adult males. The center features a variety of programs such as intensive outpatient, outpatient, and residential options, all customized to meet the specific needs of each individual. Implementing proven methodologies, including 12-step facilitation and cognitive behavioral therapy, this facility guarantees superior care. There are tailored programs available for adult men, as well as individuals who have faced intimate partner violence or sexual abuse. HealthWays Inc serves a diverse clientele, including adults, seniors, and young adults, fostering a nurturing atmosphere for recovery. With an emphasis on individualized treatment and a broad spectrum of services, this center is committed to assisting individuals in overcoming addiction and rebuilding their lives.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)