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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Heartview Foundation

Heartview Foundation, situated in Cando, ND, provides a wide array of treatment options for individuals battling addiction, including adults and teenagers. The center specializes in detox services, intensive outpatient care, long-term residential facilities, and general outpatient treatment. By employing various methods such as 12-step support, brief interventions, and cognitive behavioral techniques, Heartview Foundation customizes each treatment plan to address the unique needs of its clients. There are specific programs designed for adult men, adult women, and those facing both mental health issues and substance use challenges. With a commitment to high-quality care, this center supports both male and female individuals with understanding and professionalism, establishing itself as a reliable resource for effective rehabilitation.

Heartview Foundation

Heartview Foundation, located in Bismarck, ND, delivers a full spectrum of addiction recovery solutions for both adults and young people. Their offerings include withdrawal management, structured day treatment, extended live-in support, and flexible outpatient plans. Employing approaches like 12-step guidance, short-term counseling, and cognitive behavioral therapy, this institution serves individuals dealing with combined mental health and substance dependency issues. Heartview Foundation also distinguishes itself with dedicated tracks for adult men and women, providing customized support based on gender. Their dedication to high-standard treatment and personalized recovery paths positions them as a leading option for those in search of impactful and encouraging rehabilitation.

Heartview Fountation

Heartview Foundation in Bismarck, ND, provides extensive care for adults and young adults grappling with addiction. Their offerings include detoxification and various treatment modalities, such as intensive outpatient, outpatient, and day treatment services. Utilizing proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center aids individuals in their journey to recovery. Heartview Foundation is particularly adept at supporting those with co-occurring mental health and substance use issues, as well as pregnant and postpartum women. Tailored to meet the needs of both male and female patients, the facility emphasizes personalized support and complete wellness for everyone aiming to conquer substance dependence.

Heartview Foundation

Heartview Foundation, situated in Bismarck, ND, delivers a wide range of addiction recovery services tailored for both adults and young adults. The center offers extensive residential programs, including detoxification and continuous support available around the clock. Utilizing proven therapeutic methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, Heartview Foundation addresses the unique needs of its clients. The facility features specialized programs designed for adult men, adult women, and those dealing with both mental health issues and substance abuse. With an emphasis on personalized care, Heartview Foundation is committed to providing customized treatment plans for every individual. Valuing compassion and excellence, the center is focused on assisting clients throughout their recovery process.

Heartland Family Service
Council Bluffs, IA

Heartland Family Service in Council Bluffs, IA, delivers complete addiction care for adults dealing with concurrent severe mental health conditions, or for children experiencing emotional disruptions. Their robust intensive outpatient and outpatient services utilize proven methods such as cognitive behavioral therapy, strategies for managing anger, and concise intervention techniques. This establishment serves adult males, teenagers, and active military individuals. Through distinct programs designed for seniors and adult men, Heartland Family Service offers customized support addressing varied requirements. Their outpatient options for methadone/buprenorphine and naltrexone treatment underscore a complete recovery strategy. Prioritizing excellent service, this center is dedicated to assisting individuals of any gender who are struggling with substance use disorders.

Heartland Center for Behavioral Change

Located in Kansas City, MO, the Heartland Center for Behavioral Change provides an extensive array of services aimed at helping adults and young adults facing challenges with substance use and concurrent mental health conditions. The center's offerings include intensive outpatient programs, regular outpatient services, and day treatment. Emphasizing methods such as anger management, cognitive behavioral therapy, and the Matrix Model, the facility customizes its treatment plans to meet the unique needs of each individual. There are specialized programs designed for adult men, adult women, and those who have undergone traumatic experiences. Heartland Center for Behavioral Change is dedicated to delivering high-quality, tailored care to ensure effective recovery for all clients.

Heartland Family Service

Heartland Family Service, located in Omaha, NE, provides outpatient services for individuals dealing with substance use issues alongside mental health conditions. The facility features targeted programs designed for adult men, adult women, and those who have faced traumatic experiences. Their treatment methods incorporate anger management, cognitive behavioral therapy, and short-term interventions. Catering to both adult and senior populations, this center is distinguished by its commitment to offering personalized care and comprehensive treatment options. Additionally, Heartland Family Service includes outpatient treatments with methadone, buprenorphine, or naltrexone, fostering a well-rounded approach to addiction recovery for those in need of assistance.

Heartland Counseling Clinic

Heartland Counseling Clinic, located in Lexington, NE, specializes in outpatient care for adults and youth facing substance use challenges alongside significant mental health conditions. Employing techniques such as anger management, cognitive behavioral therapy, and brief intervention, they deliver targeted support for individuals impacted by trauma or co-occurring disorders. The clinic offers customized recovery pathways for adult men and women, as well as seniors, within a nurturing setting. Their commitment to high standards and personalized treatment distinguishes them in their integrated approach to concurrently managing addiction and mental health issues. Experience effective and empathetic treatment at Heartland Counseling Clinic.

Heartland Wellness Center

Heartland Wellness Center, located in Lowell, IN, delivers an extensive selection of treatment options for substance use tailored for both adults and young adults. Emphasizing the importance of addressing co-occurring mental health conditions, the center features a variety of services, including intensive outpatient care, outpatient day programs, and partial hospitalization. The methodologies employed at the facility range from 12-step support to anger management and brief intervention tactics. Heartland Wellness Center is equipped to assist clients who have faced trauma, individuals with dual disorders, as well as those who are part of the criminal justice system. With programs specifically designed for both men and women, the center fosters a nurturing environment for individuals seeking to embark on their recovery journey.

Hegira Health Inc

Hegira Health Inc, located in Livonia, MI, specializes in a wide range of substance abuse treatments for both adults and children dealing with concurrent mental health issues. The center provides intensive outpatient and outpatient programs, including services for methadone and buprenorphine. Utilizing proven techniques such as cognitive behavioral therapy and the Matrix Model, Hegira Health Inc addresses the unique needs of clients, including those with traumatic experiences, co-occurring conditions, and those affected by the criminal justice system. The center accommodates both male and female patients, ensuring that care is personalized for each individual. Committed to delivering quality and empathetic treatment, Hegira Health Inc plays an essential role in helping individuals navigate their recovery journey.

Hegira Health Inc

Hegira Health Inc, located in Taylor, MI, provides a wide range of substance use recovery services for both adults and children facing significant mental health challenges or emotional issues. The center offers both intensive outpatient and outpatient options, including treatments with methadone and buprenorphine. By implementing techniques such as brief interventions, cognitive behavioral therapy, and the Matrix Model, the center addresses the needs of those impacted by intimate partner violence, sexual trauma, or other adverse experiences. Hegira Health Inc serves both men and women, ensuring that care is tailored to meet the unique needs of each gender. Committed to delivering high-quality care and personalized treatment plans, this facility is focused on assisting individuals as they work towards recovery.

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Heartland Center for Behavioral Change, located in Liberty, MO, specializes in providing targeted treatment for substance use disorders among adults and young adults. This center emphasizes intensive outpatient programs and outpatient options that utilize methadone, buprenorphine, or naltrexone, ensuring a personalized treatment experience through proven methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Notably, the center has customized programs that cater specifically to clients involved with the criminal justice system. Offering thorough assistance to both men and women, Heartland Center for Behavioral Change is dedicated to delivering high-quality support for individuals on their journey to recovery from substance use issues.

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Heartland Counseling Clinic, located in Mc Cook, NE, specializes in outpatient treatment for substance use issues, as well as offering tailored support for individuals facing both substance use disorders and significant mental health challenges. The center incorporates approaches such as anger management, brief intervention, and cognitive behavioral therapy to effectively meet a wide range of client needs. Catering to both adults and seniors, the clinic provides trauma-informed care and guidance for those dealing with dual diagnoses. Customized treatment strategies are developed for all clients, regardless of gender, ensuring a holistic and personal approach to recovery. Heartland Counseling Clinic is committed to delivering high-quality, evidence-based care that fosters healing and promotes long-term wellness.

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Heartland Counseling Clinic, located in Ogallala, NE, provides outpatient treatment for substance use disorders as well as specialized services for individuals facing both substance use and severe mental health issues. The clinic emphasizes methods like anger management, brief interventions, and cognitive behavioral therapy, serving adults and seniors. It offers customized programs aimed at those who have undergone trauma or possess dual diagnoses. Catering to both men and women, the center is committed to delivering exceptional care through various evidence-based strategies. Those in need of assistance for substance use or mental health challenges can discover thorough and empathetic treatment options at Heartland Counseling Clinic.

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Heartland Counseling Clinic, located in North Platte, NE, provides outpatient services aimed at addressing substance abuse and associated mental health conditions for both adults and children. The center employs a range of strategies including anger management, brief interventions, and cognitive behavioral therapy, specifically designed for those who have faced trauma or have dual diagnoses. Catering to a diverse population of adults and seniors, Heartland Counseling Clinic offers personalized care that meets the unique needs of each individual. With a focus on high-quality, tailored treatment, the clinic is a reliable option for those in need of effective rehabilitation support in a nurturing setting.

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Heartland Family Service in Omaha, NE, delivers a full spectrum of recovery support for adults and young adults managing addiction and co-occurring mental health challenges. They offer robust outpatient, extended residential stays, and standard outpatient services, employing methods such as 12-step guidance, anger management techniques, and brief intervention strategies. The center also provides tailored services for adult women, those affected by domestic abuse, violence, or sexual trauma, addressing a wide range of individual circumstances. Heartland Family Service distinguishes itself through its empathetic and skilled approach to client care, guaranteeing excellent support for both men and women on their journey to wellness.

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Chataignier, LA

Heartland Recovery LLC, located in Chataignier, LA, delivers targeted care for individuals struggling with substance use disorders and co-occurring mental health conditions, catering to both adult and adolescent populations. The facility provides both residential and intensive short-term residential care, incorporating therapeutic modalities such as 12-step facilitation, anger management, and brief intervention strategies. Specific programming is available for adult men, adult women, and those with a history of sexual trauma, promoting personalized recovery journeys. Serving a diverse range of adults and young adults of all gender identities, this center fosters a nurturing atmosphere for effective treatment. For those in search of thorough rehabilitation that emphasizes integrated well-being and customized treatment plans, Heartland Recovery LLC is committed to supporting individuals on their path to sustained recovery.

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Westland, MI

Hegira Health Inc, located in Westland, MI, provides a wide range of substance abuse treatments for both adults and young individuals dealing with co-existing mental health issues. Their intensive outpatient and outpatient services feature a variety of treatment options, including methadone/buprenorphine and naltrexone therapies, designed to meet different client needs. The center employs evidence-based methods such as cognitive behavioral therapy and the Matrix Model to deliver tailored support, particularly for those involved in the criminal justice system and clients with dual diagnoses. With dedicated programs for both male and female participants, Hegira Health Inc emphasizes personalized, high-quality care aimed at fostering sustained recovery and overall wellness.

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Lincoln Park, MI

Hegira Health Inc, situated in Lincoln Park, MI, provides extensive outpatient care for individuals struggling with substance abuse and co-occurring mental health challenges, as well as emotional issues in young people. They offer targeted support for those who have experienced intimate partner violence, domestic abuse, sexual assault, and trauma. Employing proven therapeutic methods like brief intervention, cognitive behavioral therapy, and the Matrix Model, Hegira Health Inc serves clients of all genders and age groups. Their commitment to high-quality, personalized treatment plans guides individuals toward lasting recovery.

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Westland, MI

Hegira Health Inc in Westland, MI, provides extensive care for individuals struggling with substance use disorders. They offer several outpatient treatment avenues, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient services, and short-term intervention counseling. Specializing in motivational interviewing and strategies for preventing relapse, Hegira Health Inc delivers personalized support to adults and older adults, accommodating all genders. Their commitment to a client-centered methodology ensures that the services rendered are of the highest standard, fostering lasting recovery. This center is dedicated to creating a nurturing atmosphere for those on their journey to wellness and personal development.

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Westland, MI

Hegira Health Inc, located in Westland, MI, delivers specialized outpatient substance use disorder services, with a particular focus on individuals facing co-occurring mental health conditions. Their program encompasses medication-assisted treatment options like methadone, buprenorphine, and naltrexone, alongside general outpatient services. Employing strategies such as motivational interviewing, cognitive behavioral therapy, and the Matrix Model, they create personalized recovery plans. Hegira Health Inc also features distinct programs designed for active duty military personnel, adult men, and adult women, ensuring targeted support. Catering to adults and young adults of all genders, the center is committed to providing effective, scientifically-backed treatment within a supportive atmosphere.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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