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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Heights Treatment

Heights Treatment, based in Houston, TX, presents a wide array of substance abuse recovery programs tailored for both adults and young adults. This facility focuses on addressing co-occurring substance use issues alongside significant mental health conditions. It offers various treatment options, including intensive outpatient programs, outpatient services, and day treatment, all designed to meet the individual needs of clients. Heights Treatment employs methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, ensuring that the care provided is rooted in evidence-based practices. Specialized programs are also available for active military personnel, as well as for adult men and women. With an emphasis on delivering high-quality care and customized treatment strategies, Heights Treatment is a reputable option for individuals pursuing recovery.

Hello House Burt Street
Dorchester Center, MA

Situated in Dorchester Center, MA, Hello House Burt Street is a premier rehabilitation center dedicated to providing long-term residential treatment for adult men facing challenges related to substance use disorders and concurrent severe mental health issues. The facility delivers a well-rounded program that integrates 12-step facilitation, anger management strategies, and brief intervention techniques to meet the diverse needs of its clients. What sets Hello House Burt Street apart is its commitment to supporting individuals who have endured trauma, in addition to those dealing with both mental health challenges and substance use. With tailored programs designed for adult men, seniors, and young adults, this center ensures personalized care and assistance to foster enduring recovery.

Helen Ross McNabb Center

The Helen Ross McNabb Center in Knoxville, TN, delivers tailored rehabilitation programs designed for diverse treatment requirements. This establishment features robust outpatient services, including intensive outpatient, day treatment, and partial hospitalization, serving adults, youth, and young adults grappling with addiction and concurrent mental health challenges. Employing strategies such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center personalizes its therapeutic interventions. Specialized tracks for adult men, adult women, and individuals with trauma histories underscore its dedication to holistic support. The center’s gender-specific treatment modalities for men and women exemplify its pledge to superior and equitable rehabilitation care.

Helen Ross McNabb Center

Situated in Knoxville, TN, the Helen Ross McNabb Center delivers a wide range of rehabilitation services targeting substance use issues and concurrent mental health challenges for both adults and children. The center features intensive outpatient and regular outpatient options that utilize evidence-supported methods like brief interventions, motivational interviewing, and relapse prevention strategies. With focused programs designed for adult males, adult females, and survivors of sexual abuse, this facility addresses a variety of requirements. By catering to all genders among adult and young adult populations, the Helen Ross McNabb Center is committed to providing personalized care and support, prioritizing effective treatment and comprehensive recovery.

Helen Ross McNabb Center

The Helen Ross McNabb Center, located in Athens, TN, specializes in rehabilitation for both adults and seniors struggling with substance abuse and accompanying mental health challenges. The center offers a range of treatment options, including intensive outpatient services, outpatient programs, and medication-assisted treatments such as methadone, buprenorphine, or naltrexone. Each program is personalized to address the unique needs of each client. The center employs research-supported methods such as cognitive behavioral therapy and motivational interviewing to foster recovery. Additionally, there are dedicated programs for adult men and women, as well as individuals who have faced sexual abuse. Committed to delivering high-quality care, this facility provides a nurturing atmosphere for clients on their path to recovery and personal development.

Helio Health Inc
Rochester, NY

Helio Health Inc, located in Rochester, NY, provides extensive detox programs within a nurturing setting. With a focus on residential detox and round-the-clock support, this center employs customized treatment strategies founded on proven methods, including 12-step programming, cognitive behavioral therapy, and contingency management. The facility features specialized programs for adult men and women, as well as those who have faced intimate partner or domestic violence. Helio Health Inc serves a diverse clientele, including adults, children, adolescents, and young adults of any gender, prioritizing personalized treatment plans to ensure exceptional care.

Helio Health Inc
Syracuse, NY

Helio Health Inc. in Syracuse, NY, delivers extensive support for adults battling substance use disorders, notably including individuals with significant mental health challenges. Their residential and transitional living services employ proven therapeutic methods like 12-step program integration, emotional regulation strategies, and motivational interviewing. While serving adults and young adults across all genders, the program places a particular emphasis on assisting adult men. Helio Health Inc. is dedicated to providing exceptional care aimed at fostering enduring sobriety and well-being. For those in need of a nurturing setting to address addiction and co-occurring mental health issues, this center presents a strong option.

Helio Health Inc
Syracuse, NY

Helio Health Inc in Syracuse, NY, is dedicated to offering comprehensive addiction recovery solutions. Their services include inpatient detox, continuous residential support around the clock, and abbreviated residential stays designed for adults, older adults, and younger adults. Helio Health Inc emphasizes personalized recovery journeys, integrating methodologies such as 12-step facilitation, emotional regulation training, and prompt intervention strategies within their therapeutic frameworks. This establishment welcomes individuals of all genders, fostering an atmosphere of encouragement. Patients can anticipate superior care that addresses their unique circumstances, establishing Helio Health Inc as a crucial provider of successful and customized addiction treatment.

Helen Ross McNabb
Maryville, TN

Helen Ross McNabb, situated in Maryville, TN, is a respected addiction recovery facility. They provide distinct therapeutic plans for individuals dealing with substance abuse and concurrent mental health conditions. Services include comprehensive outpatient care, general outpatient support, and medication-assisted treatment options. Employing methods like cognitive behavioral therapy and motivational interviewing, this establishment serves adults and older adults, alongside specific offerings for teenagers, adult males, and adult females. Dedicated to personalized recovery journeys, Helen Ross McNabb guarantees effective treatment for all clients, irrespective of gender, pursuing sobriety.

Helen Ross McNabb Center

Situated in Morristown, TN, the Helen Ross McNabb Center provides exceptional care for individuals grappling with substance use issues alongside significant mental health challenges. Their offerings encompass intensive outpatient programs, outpatient care, and medication-assisted treatment alternatives such as methadone and buprenorphine. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, this center serves a diverse clientele, including adults, children, and the elderly, featuring particular programs aimed at adolescents, adult men, and women. With a commitment to personalized treatment for both genders, this facility is dedicated to delivering effective support for individuals on their recovery journey.

Helping Hand Association

Helping Hand Association, situated in West Jordan, UT, provides extended residential recovery for adult males. This program fosters a structured and encouraging atmosphere, concentrating on 12-step integration, emotional regulation techniques, and concise therapeutic interventions. It serves adult males, older individuals, and younger adults facing past traumas or legal challenges. Emphasizing personalized attention and a male-focused strategy, Helping Hand Association offers a secure space for men on their path to healing and community re-entry via transitional, halfway, or sober living arrangements.

Helping Hand Association
Salt Lake City, UT

Situated in Salt Lake City, UT, the Helping Hand Association provides extensive recovery support for adults and young adults facing addiction challenges. Their offerings include intensive outpatient, day treatment, and partial hospitalization programs. The center emphasizes 12-step facilitation, anger management, and brief intervention strategies, with specialized programs for individuals who have undergone trauma. Dedicated tracks are available for adult men and women, promoting personalized healing journeys. Furthermore, the facility provides transitional housing, halfway house accommodations, and sober living environments for both male and female residents, fostering a secure and encouraging space for sustained sobriety.

Helen Ross McNabb Center

Situated in Knoxville, TN, the Helen Ross McNabb Center delivers a wide range of rehabilitation services aimed at adults and young adults facing challenges with substance abuse alongside mental health disorders. The facility provides options for residential detox and short-term residential care, employing proven methods like cognitive behavioral therapy and motivational interviewing. Emphasizing personalized treatment, the center features tailored programs for adult men, adult women, and individuals who have endured sexual abuse. The dedicated staff supports both male and female clients, fostering an encouraging and inclusive atmosphere conducive to healing.

Helen Ross McNabb Center

Nestled in Oak Ridge, TN, the Helen Ross McNabb Center provides extensive substance use recovery options for individuals of all ages dealing with co-occurring severe mental health conditions. Their offerings encompass intensive outpatient services, standard outpatient programs, and targeted outpatient care involving methadone, buprenorphine, or naltrexone. Employing proven methods like cognitive behavioral therapy and motivational interviewing, this institution delivers personalized support for adult men, women, and trauma survivors. Catering to adults and seniors of all genders, the center is dedicated to delivering excellent treatment and assistance within a supportive setting for those pursuing successful recovery.

Helping Associates Inc
Casa Grande, AZ

Helping Associates Inc, located in Casa Grande, AZ, specializes in outpatient treatment for substance use disorders and offers targeted support for individuals facing both substance use and significant mental health challenges. The facility employs regular outpatient services that incorporate evidence-based techniques such as cognitive behavioral therapy, anger management, and short-term interventions. Aiming to provide personalized care, the center serves adults and seniors of diverse backgrounds. Its dedication to high-quality treatment and customized recovery plans positions it as a top option for individuals looking for thorough and impactful rehabilitation in a nurturing setting.

Helen Ross McNabb Center

The Helen Ross McNabb Center in Chattanooga, TN, provides extensive support for individuals grappling with addiction and dual diagnoses. They specialize in treating co-occurring substance use disorders and severe mental health challenges in adults, alongside emotional difficulties experienced by children. Their offerings include intensive and standard outpatient services, featuring medication-assisted treatment with methadone and buprenorphine. Employing scientifically validated methods such as cognitive behavioral therapy and motivational interviewing, the center designs distinct programs for adult men, women, and those who have experienced sexual trauma, ensuring personalized recovery journeys. Catering to adults and young adults of all genders, this institution delivers high-caliber recovery assistance aimed at fostering sustained well-being and comprehensive health.

Helping Hand Association
Salt Lake City, UT

Situated in Salt Lake City, UT, the "Helping Hand Association" provides long-term residential treatment for adult men struggling with substance use issues. This center is dedicated to offering various options such as transitional housing, halfway houses, or sober living arrangements. Their programs emphasize 12-step methodologies, anger management, and brief intervention techniques. They serve adult men, including individuals who have faced trauma or who are part of the criminal justice system. With services designed for seniors, young adults, and those in between, this facility delivers holistic care within a nurturing atmosphere. The Helping Hand Association is a commendable option for those pursuing personalized addiction recovery support.

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The Helen Ross McNabb Center in Sevierville, TN, delivers thorough addiction treatment for youth and adults facing significant mental health challenges. Through intensive and standard outpatient programs, it offers tailored support for those with dual diagnoses. The center employs strategies like brief intervention, cognitive behavioral therapy, and motivational interviewing, serving adult men and women, including survivors of sexual trauma. Catering to adults and older adults of all genders, the Helen Ross McNabb Center is dedicated to providing superior, personalized care to aid individuals in their recovery journey.

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Liverpool, NY

Helio Health Inc, located in Liverpool, NY, is dedicated to providing extensive residential care for individuals battling substance abuse and related mental health challenges, serving both adults and young adults. Utilizing proven therapeutic methods including 12-step support, emotional regulation techniques, and cognitive restructuring, the facility crafts personalized recovery journeys. Helio Health Inc caters to distinct client groups with specialized programs for adult men, adult women, and those managing co-occurring disorders, ensuring a nurturing atmosphere for healing. Their commitment to unique treatment strategies and gender-sensitive care guarantees high standards for everyone pursuing sobriety. For those in need of expert addiction services, this center presents a caring and successful route to recovery.

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South Jordan, UT

The Helping Hand Association, situated in South Jordan, UT, provides comprehensive long-term residential care for substance use disorders, alongside transitional housing and sober living arrangements. This establishment focuses on 12-step integration, anger management techniques, and brief intervention strategies tailored for adult women affected by trauma, individuals with forensic histories, and those navigating the legal system. Catering to adult women, including seniors and young adults, the center ensures round-the-clock support within a nurturing setting. The Helping Hand Association in South Jordan is committed to offering exceptional, individualized support to individuals pursuing freedom from addiction.

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Egg Harbor Township, NJ

Nestled in Egg Harbor Township, NJ, Helping Hand Behavioral Health is dedicated to providing expert care for individuals grappling with substance use disorders and co-occurring mental health conditions. Serving adults and young adults, their programs emphasize intensive outpatient and day treatment services. They incorporate evidence-based therapies such as 12-step facilitation, anger management, and brief intervention strategies. Notably, Helping Hand Behavioral Health distinguishes itself with specialized tracks for adult men, adult women, and those affected by intimate partner violence, offering a personalized approach for every client. They welcome both male and female individuals seeking compassionate and successful recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)