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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Alexian Brothers BH Hosp

Situated in Schaumburg, IL, the Alexian Brothers BH Hosp delivers thorough addiction recovery services for both adults and children facing substance misuse and concurrent mental health challenges. The center features specialized programs catering to adolescents, adult males, and individuals with dual diagnoses, offering inpatient detox and treatment grounded in evidence-based methodologies such as 12-step facilitation, brief interventions, and cognitive behavioral therapy. Customized treatment plans are developed for male and female adults and seniors, ensuring personalized care. The facility's dedication to high-quality treatment and its emphasis on meeting individual needs position it as a reliable option for those in search of effective rehabilitation support.

Align Recovery Centers

Align Recovery Centers located in Sonoma, CA, provides a wide range of addiction treatment services aimed at adults and young adults struggling with substance abuse issues and co-existing mental health challenges. The facility features hospital inpatient detox and treatment options, along with specific programs designed for active-duty military members, as well as adult men and women. Emphasizing approaches such as 12-step facilitation, anger management, and cognitive behavioral therapy, the center customizes its treatment plans to meet the unique needs of each individual. Catering to both male and female clients, Align Recovery Centers is dedicated to offering top-tier care in a nurturing environment to support clients on their path to sustainable recovery.

All Addiction Recovery LLC
West Palm Beach, FL

All Addiction Recovery LLC, located in West Palm Beach, FL, provides an extensive range of addiction treatment services, including detox programs, substance use therapy, and targeted support for individuals facing both addiction and mental health challenges, whether adults or children. The center offers various options such as residential detoxification, around-the-clock residential care, and short-term residential treatment. Emphasizing techniques like 12-step facilitation, anger management, and brief therapeutic interventions, this facility is designed for active military members and adults of all genders. Committed to delivering exceptional care in a nurturing atmosphere, this center supports individuals in their journey towards overcoming addiction.

All In Solutions California

All In Solutions California, situated in Simi Valley, CA, specializes in extensive detox and treatment services for substance use. This center offers various options, including intensive outpatient programs, outpatient services, and partial hospitalization. Emphasizing methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, the facility customizes its strategies to fit the unique needs of each client. It features specialized programs designed for adult men, adult women, and those who have gone through traumatic experiences. Catering to both adults and young adults from all backgrounds, the center fosters a supportive and welcoming atmosphere for recovery. With a strong commitment to providing high-quality care, All In Solutions California aims to assist individuals in overcoming addiction and attaining sustainable sobriety.

All In Solutions Counseling Center

Situated in Cherry Hill, NJ, All In Solutions Counseling Center offers a variety of evidence-supported treatment options for those facing challenges related to substance abuse and concurrent mental health issues. The facility provides options such as intensive outpatient, outpatient, and day treatment, employing methodologies including 12-step support, brief intervention, and cognitive behavioral techniques. Tailored programs are available for adult men, adult women, and clients with experiences of sexual trauma. By prioritizing the needs of adults and young adults, the center guarantees personalized attention for both male and female participants. All In Solutions Counseling Center is committed to delivering high-quality, all-encompassing care to aid individuals on their path to recovery.

All in Solutions Counseling Center LLC

All in Solutions Counseling Center LLC, located in Boynton Beach, FL, provides extensive support for individuals battling substance use disorders, alongside transitional living accommodations. The center has tailored programs designed for adult men and women, and those with a history of sexual trauma, ensuring each person's unique requirements are met. Treatment options encompass intensive outpatient and day treatment programs, incorporating proven methods like 12-step encouragement, emotional regulation skills, and concise counseling interventions. Catering to adults and young adults across all gender identities, the center fosters a nurturing space for healing. Prioritizing exceptional care and customized treatment plans, All in Solutions Counseling Center LLC is committed to guiding individuals toward sustained abstinence.

All Opiates Detox
Wyandotte, MI

All Opiates Detox in Wyandotte, MI, delivers thorough detox services and addiction treatment. Their offerings include intensive outpatient care, standard outpatient services, and partial hospitalization programs. This center is dedicated to adult men, adult women, and young adults, creating a nurturing setting for those pursuing sobriety. Welcoming both genders, the programs are customized for adults and young adults facing addiction challenges. Their all-encompassing strategy guarantees excellent support for individuals aiming to overcome substance dependency.

All Points North Lodge

All Points North Lodge, situated in Edwards, CO, presents a wide array of rehabilitation options for both adults and young adults. The center specializes in detox services, treatment for substance use disorders, and tailored support for individuals facing both substance use challenges and significant mental health conditions. With a variety of treatment modalities including intensive outpatient therapy, long-term residential stays, and standard outpatient care, it addresses varying client requirements. The Lodge employs methods such as 12-step programs, anger management, and brief intervention strategies. Additionally, it offers unique programs targeted to active military members, as well as separate offerings for adult men and women. All Points North Lodge places a strong emphasis on delivering high-quality, personalized care for clients striving for recovery from addiction.

Allendale Treatment

Allendale Treatment in Auburn, IN, delivers thorough recovery support for adults and adolescents facing addiction and concurrent mental health challenges. Their expertise lies in inpatient hospital detoxification and care, featuring tailored tracks for adult men, adult women, and survivors of intimate partner or domestic abuse. By employing 12-step facilitation, anger management techniques, and brief intervention strategies, the center delivers personalized support to foster sustained healing. Catering to both male and female individuals, Allendale Treatment is committed to offering premium, evidence-backed therapy in a nurturing setting.

Alexian Brothers/Foglia Family
Elk Grove Village, IL

Situated in Elk Grove Village, IL, the Alexian Brothers/Foglia Family center delivers exceptional substance use rehabilitation in a residential environment. The facility specializes in short-term residential programs that emphasize 12-step facilitation, brief interventions, and cognitive behavioral therapy. Focusing on individualized care, the center serves both adults and young adults across all gender identities. Its distinctive methodology guarantees customized treatment strategies for everyone, ensuring superior care and support during the recovery process. If you are looking for personalized and effective addiction treatment, this center is committed to guiding you towards lasting sobriety.

Allens Family Counseling Center Inc

Allens Family Counseling Center Inc, situated in Chicago, IL, provides a complete suite of recovery programs. The facility's expertise lies in addressing addiction and intertwined mental health conditions for both young and adult individuals. They offer various treatment levels, including intensive outpatient, standard outpatient, and less intensive outpatient options. Emphasis is placed on guiding clients through 12-step principles, managing anger, and employing short-term intervention strategies. Their services are available to active military personnel, teenagers, and adult males. Catering to a broad demographic, the center assists individuals of all ages and genders, ensuring personalized support for each client. The dedication to high-quality care and its diverse specialized offerings make Allens Family Counseling Center Inc a premier destination for effective therapeutic support.

AllHealth Network
Littleton, CO

Situated in Littleton, CO, AllHealth Network specializes in rehabilitation services aimed at addressing substance use disorders alongside co-existing mental health issues for both adults and children. The center offers various treatment options, including intensive outpatient programs, standard outpatient services, as well as methadone/buprenorphine or naltrexone therapies. Employing methods such as cognitive behavioral therapy and contingency management, AllHealth Network serves clients who have experienced trauma and those with dual diagnoses. The facility provides programs designed specifically for adolescents and individuals facing co-occurring disorders, ensuring holistic care for all clients, regardless of gender, in a nurturing recovery-focused atmosphere.

Alfre Inc
Morristown, NJ

Alfre Inc, located in Morristown, NJ, is a leading facility dedicated to assisting women with substance abuse and co-occurring mental health challenges. They offer a full spectrum of care, including intensive outpatient, extended residential stays, and standard outpatient services. Their treatment methodologies include 12-step facilitation, anger management, and brief intervention strategies. Notably, Alfre Inc provides specialized support for adult women who have experienced intimate partner violence, domestic abuse, and sexual assault. Serving adult women, seniors, and young adults, Alfre Inc is distinguished by its tailored approach and its unwavering dedication to fostering sustained recovery and overall well-being.

Aliviane Inc
El Paso, TX

Aliviane Inc, located in El Paso, TX, provides extensive addiction treatment services, specializing in intensive outpatient, outpatient, and medication-assisted treatment options including methadone, buprenorphine, and naltrexone. Utilizing scientifically proven methods such as anger management, cognitive behavioral therapy, and motivational interviewing, this establishment delivers customized support to adults, youth, and young adults regardless of gender. A key distinction of Aliviane Inc is its creation of unique treatment itineraries, guaranteeing customized assistance for every individual. With an unwavering dedication to superior care, Aliviane Inc is committed to guiding people toward a life free from addiction.

Allegany County Health Department

The Allegany County Health Department in Cumberland, MD, delivers thorough detox and substance abuse recovery services. This establishment provides inpatient hospital detox, treatment, and round-the-clock support for adults and young adults, regardless of gender. Featuring distinct programs for adult men and women, the center employs methods including 12-step facilitation, anger management, and brief intervention tailored to personal requirements. Dedicated to superior care, this facility prioritizes customized recovery plans to assist individuals in their journey to sobriety. For effective and individualized addiction treatment, the Allegany County Health Department stands ready to assist.

Align Group Homes
San Tan Valley, AZ

Situated in San Tan Valley, AZ, Align Group Homes delivers comprehensive long-term residential treatment for substance use in a nurturing setting. The facility features transitional housing, halfway housing, and sober living arrangements for adult men and women. Programs specifically designed for active duty military members are also offered. Emphasizing 12-step methods, anger management, and brief intervention, this center serves both young and adult residents in need of effective care. With specialized offerings for each gender, Align Group Homes is committed to supporting individuals as they progress on the path to recovery.

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Alhambra Valley Retreat LLC, located in Martinez, CA, provides extensive treatment for adult men struggling with substance use issues. This center is particularly focused on addressing co-existing substance use problems and significant mental health challenges among adults, alongside severe emotional issues in children. Offering both long-term and short-term residential options, as well as 24/7 care, the facility customizes its treatment strategies, incorporating methods like 12-step programs, anger management, and quick intervention techniques. Special initiatives are designed for adult men, as well as individuals affected by intimate partner violence, domestic violence, or sexual abuse. Catering to adults, seniors, and young adults, this center emphasizes high-quality, personalized care aimed at achieving sustainable recovery.

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Allcare Treatment Services LLC, located in Glen Burnie, MD, provides extensive outpatient substance abuse treatment. The center features tailored programs designed for adult men, adult women, and young adults, accommodating various age ranges. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, this facility offers customized support for both genders. Treatment options include outpatient methadone/buprenorphine or naltrexone therapies, in addition to standard outpatient services. Those looking for effective, research-supported addiction recovery can access high-quality care and assistance at Allcare Treatment Services LLC.

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Allegany Council on Alc/Subst Abuse in Wellsville, NY, provides outpatient addiction recovery services designed for adults and seniors. Their expertise includes anger management, cognitive behavioral therapy, and brief intervention strategies, offering holistic support for individuals facing dual mental health and substance use challenges. The center prioritizes addressing past trauma and serves adult men and women. They offer medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside standard outpatient care, all within personalized and successful treatment approaches. Allegany Council on Alc/Subst Abuse is committed to delivering top-tier, research-supported services to aid those on their journey toward lasting sobriety.

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Nestled in Covington, VA, Alleghany Highlands Community Services delivers a complete spectrum of care for adults and young people struggling with addiction and co-occurring mental health issues. The facility offers a range of services including intensive outpatient, standard outpatient, and medication-assisted treatments like methadone, buprenorphine, and naltrexone, all customized to meet each person's unique requirements. They feature distinct programs for individuals with dual diagnoses and those involved in the legal system, incorporating tools such as 12-step program support, anger management techniques, and short-term therapeutic interventions. Catering to both men and women, the center is committed to delivering high-quality, evidence-supported methods to aid in the recovery journey for those navigating addiction and mental health complexities.

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Situated in Sidman, PA, Allegiance Rehabilitation Center delivers an extensive array of treatment options for those facing addiction challenges. This center offers long-term residential rehabilitation, detoxification services, and round-the-clock assistance. The program integrates 12-step methodologies, anger management techniques, and brief intervention strategies to tackle substance use issues efficiently. With tailored programs for adult males, adult females, and individuals who have experienced sexual trauma, Allegiance Rehabilitation Center serves a wide spectrum of clients. Catering to both adult and young adult populations of all genders, the facility guarantees individualized care and support for every person’s recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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