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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Allure Detox
West Palm Beach, FL

Situated in West Palm Beach, Florida, Allure Detox stands out as a leading rehabilitation facility dedicated to detoxification and treatment for substance use disorders. The center provides tailored support for adults facing both substance use challenges and significant mental health issues. Offering inpatient hospital care with 24/7 supervision, Allure Detox employs proven methods such as 12-step facilitation and anger management therapy. The center features specialized programs designed for adult men and women, including those who have encountered intimate partner or domestic violence. With an emphasis on personalized and high-quality care, Allure Detox creates a safe and nurturing atmosphere for both adults and young adults seeking recovery.

Aloha Behavioral Consultants Inc

Aloha Behavioral Consultants Inc, located in Ogden, UT, provides a variety of focused rehabilitation services. This center is equipped to handle detox and substance use treatment for both adults and seniors, including those battling simultaneous severe mental health disorders. Featuring intensive outpatient and outpatient programs, the facility employs methods like anger management, short interventions, and cognitive behavioral therapy. A distinctive aspect of this program is its personalized treatment plans designed to meet the needs of both male and female clients. Aloha Behavioral Consultants Inc is committed to delivering exceptional care aimed at supporting individuals in their journey toward sustainable recovery.

Aloha Detox Center LLC
Delray Beach, FL

Aloha Detox Center LLC, located in Delray Beach, FL, provides thorough care for individuals struggling with withdrawal, addiction, and co-occurring mental health issues, serving both adults and adolescents. The facility features hospital-level inpatient detox and treatment, offering continuous care around the clock. Their therapeutic methods include 12-step facilitation, anger management techniques, and brief intervention strategies. Aloha Detox Center LLC also has dedicated programs for active military personnel, teenagers, and adult men. They welcome individuals of all genders and ages, ensuring personalized treatment plans. For those in search of expert and focused addiction recovery services, this center offers a nurturing atmosphere conducive to healing and rebuilding lives.

Alpha Recovery Center

In Lancaster, California, Alpha Recovery Center delivers a full spectrum of substance abuse treatment. The center features inpatient detox, continuous 24-hour residential support, and brief residential stays designed for adults and young adults. Addressing dual diagnoses of addiction and mental health issues, Alpha Recovery Center employs proven therapeutic methods such as 12-step support, anger management techniques, and concise intervention strategies. Distinctive treatment paths for active military members, adult males, and adult females are available, promoting customized care. Prioritizing excellent and tailored recovery plans, the center is committed to guiding individuals toward sustained healing.

Alpine Recovery Lodge

Situated in Alpine, UT, Alpine Recovery Lodge delivers an extensive array of treatment options designed for both adults and young adults facing challenges with substance use and co-existing mental health issues. The center features programs including intensive outpatient care, long-term residential stays, and outpatient therapies, all grounded in evidence-based practices like 12-step support, anger management, and short-term interventions. Tailored initiatives are available for adult men and women, as well as individuals who have encountered intimate partner or domestic violence. By emphasizing personalized care and gender-sensitive approaches, this center is committed to offering exceptional rehabilitation services that aid clients in attaining sustainable recovery.

Alpine Springs
Linesville, PA

Situated in Linesville, PA, Alpine Springs serves as a distinguished rehabilitation center that provides long-term residential options and around-the-clock support for detoxification and recovery from substance use disorders. The center is renowned for its expertise in 12-step facilitation, anger management therapies, and brief intervention strategies. Catering to both adult men and women, it also accommodates individuals who have undergone intimate partner or domestic violence. With personalized programs designed for both adults and young adults of all genders, Alpine Springs ensures a high standard of care within a nurturing atmosphere, making it an excellent option for individuals pursuing thorough and impactful addiction recovery.

Alpine Springs
Jamestown, PA

Alpine Springs, located in Jamestown, PA, specializes in rehabilitation services tailored for adults and young adults facing substance use challenges. This center offers extensive long-term residential treatment that includes detoxification services and round-the-clock support. Emphasizing 12-step principles, anger management strategies, and brief intervention techniques, Alpine Springs serves adult men and women, as well as those who have encountered intimate partner or domestic violence. Its gender-specific programs are designed to provide personalized care, promoting a nurturing atmosphere conducive to recovery. Alpine Springs is committed to providing quality, individualized treatment to assist clients in achieving sustained sobriety and enhanced well-being.

Alta Centers Inc
Los Angeles, CA

Alta Centers Inc, situated in Los Angeles, CA, delivers complete addiction recovery programs. Their expertise lies in detoxification and substance abuse treatment, featuring extended stay residential care, on-site detox, and round-the-clock residential assistance. The treatment methodology integrates 12-step facilitation, brief intervention, and cognitive behavioral therapy. They uniquely cater to active military members, adult men, and adult women. Alta Centers Inc extends its services to adults and young adults, offering customized support for both male and female individuals. Dedicated to high standards and personalized recovery, this center stands out as an excellent option for effective and nurturing rehabilitation.

Alta Mira Recovery Center LLC

Alta Mira Recovery Center LLC, located in Sausalito, CA, provides a wide array of treatment options for individuals dealing with substance use disorders alongside mental health issues. The center is particularly known for its long-term residential treatment, detox programs, and around-the-clock support. Utilizing proven techniques such as 12-step programs, anger management, and focused interventions, it emphasizes comprehensive care. The center serves both adult men and women, including those with a history of trauma, ensuring personalized treatment plans for its clients. Understanding the necessity for gender-specific programs, Alta Mira Recovery Center LLC creates customized solutions for male and female clients, fostering a nurturing and inclusive therapeutic atmosphere.

AltaPointe Health Systems Inc

AltaPointe Health Systems Inc, located in Mobile, AL, delivers targeted rehabilitation for adults and adolescents struggling with addiction and co-occurring severe mental health conditions or emotional challenges. The facility features intensive outpatient and standard outpatient options, incorporating methadone/buprenorphine therapies. Emphasizing 12-step engagement, anger management techniques, and cognitive behavioral therapy, their approach is personalized to each client's unique situation. Specialized tracks for adult men, women, and survivors of sexual abuse foster a secure and understanding atmosphere. Catering to both genders, AltaPointe Health Systems Inc provides effective treatment through a complete recovery strategy.

Alteri LLC
Lexington, KY

Alteri LLC in Lexington, KY delivers extensive outpatient recovery programs for adults and older adults facing addiction and related mental health challenges. Their tailored treatment plans address the distinct needs of adult men and women, including those who have endured trauma. Emphasizing techniques like anger management, cognitive behavioral therapy, and motivational interviewing, Alteri LLC customizes care for each individual. They also provide outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, promoting a complete path to wellness. Alteri LLC is dedicated to high-quality support for all clients on their journey to rehabilitation.

ALPHA Behavioral Health Center

ALPHA Behavioral Health Center, located in Camden, SC, provides targeted treatment for substance use via both outpatient and traditional outpatient services. Their comprehensive approach encompasses anger management, brief interventions, and cognitive-behavioral therapy. The center offers customized programs designed for adolescents, adult men, and adult women, addressing the needs of both adults and younger clients. Emphasizing personalized care, ALPHA Behavioral Health Center is open to all clients, regardless of gender, who are in pursuit of effective rehabilitation solutions. The center is committed to offering top-notch treatment options through a variety of specialized programs aimed at accommodating the unique requirements of each individual.

Alluma Inc
Crookston, MN

Alluma Inc, situated in Crookston, Minnesota, specializes in providing substance use rehabilitation for adults with significant mental health challenges and emotional issues in children. The center offers both intensive outpatient and outpatient options, utilizing treatments such as methadone, buprenorphine, or naltrexone. Clients benefit from customized support through evidence-based methods, including anger management, cognitive behavioral therapy, and motivational interviewing, all designed to aid their recovery. Alluma Inc also has a unique program specifically for adult men and is inclusive of adults and seniors across all genders. Committed to delivering high-quality care and tailored treatment strategies, this center aims to empower clients on their path to sustained sobriety and improved mental health.

Alpine Center for Personal Growth

In Salt Lake City, UT, the Alpine Center for Personal Growth provides extensive care for those addressing substance abuse and co-occurring mental health challenges. They offer intensive outpatient, day treatment, and partial hospitalization options for adults and young adults. Their therapeutic model incorporates 12-step support, anger management techniques, and brief intervention strategies, serving both men and women. Specialized programs are available for individuals with dual diagnoses and younger clients. The Alpine Center for Personal Growth is committed to delivering high-quality support to foster client development and lasting sobriety.

Alpha Home Inc
San Antonio, TX

Alpha Home Inc, situated in San Antonio, TX, delivers a wide array of long-term residential treatment solutions designed specifically for adults dealing with substance use disorders and co-occurring severe mental health conditions, as well as children facing significant emotional challenges. The center specializes in support for women, including those affected by intimate partner violence, domestic abuse, and sexual assault. By emphasizing 12-step facilitation, anger management, and brief intervention techniques, Alpha Home Inc is dedicated to providing exceptional care and assistance tailored to female clients across various age groups, from young women to seniors.

Alpha School 822 Program

The Alpha School 822 Program, situated in Brooklyn, NY, delivers tailored outpatient services for individuals, both adults and youth, contending with addiction and concurrent mental health conditions. Their offerings encompass medication-assisted treatment using methadone, buprenorphine, or naltrexone, alongside support for the 12-step model, anger control techniques, and early intervention strategies. This center serves individuals across the gender spectrum, with particular attention to those affected by relationship violence, domestic abuse, and those managing chronic pain alongside substance dependency. The Alpha School 822 Program is dedicated to providing excellent care to guide people toward lasting recovery.

Alpine Recovery Services

Alpine Recovery Services, located in Arlington, WA, specializes in providing extensive substance use treatment for both adults and young adults. The center offers a range of programs, including intensive outpatient treatment, standard outpatient options, and partial hospitalization services. Emphasizing personalized care, Alpine Recovery Services utilizes methods such as 12-step facilitation, anger management, and brief interventions to tackle addiction. Their programs are designed to meet the unique needs of both men and women, facilitating a customized recovery path for everyone. Discover exceptional care and dedicated support at this facility, which prioritizes effective treatment solutions.

ALPHA Behavioral Health Center

ALPHA Behavioral Health Center in Chesterfield, SC, delivers outpatient support for individuals grappling with substance use issues, serving both young people and adults. The center employs proven therapeutic methods like anger control strategies, concise intervention techniques, and cognitive behavioral therapy within its regular outpatient services. They offer distinct programs designed for adult men, adult women, and adolescents, ensuring that a wide range of people receive relevant care. Anyone needing effective substance use treatment in a nurturing setting may find ALPHA Behavioral Health Center to be a valuable partner in their path to recovery.

Alpha II Womens Program

Situated in Secaucus, NJ, the Alpha II Womens Program stands out as a premier rehabilitation center dedicated to addressing substance use issues and co-occurring conditions in female adults. This facility offers extensive residential treatment, available around the clock, and employs a variety of evidence-backed methods such as 12-step programs, anger management sessions, and focused interventions. The program is designed for adult women, including seniors and young adults, who have faced challenges like intimate partner violence, domestic abuse, or sexual trauma. Emphasizing personalized care and a nurturing atmosphere, this center creates a secure and empowering space for women on their journey to recovery and restoration.

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Alpha Counseling and Treatment Inc. in Abingdon, MD, delivers thorough outpatient substance use services for adults and older individuals facing co-occurring severe mental health challenges. Their expert care incorporates 12-step facilitation, brief interventions, and cognitive behavioral therapy. Alpha Counseling and Treatment Inc. emphasizes personalized care, designing programs to suit each patient's distinct requirements. Providing outpatient treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care, this center is committed to high-quality support for all clients. For tailored, science-backed treatment in a welcoming setting, this center is equipped to support your journey to wellness.

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Situated in Medina, OH, Alternative Paths Inc delivers a wide array of rehabilitation services. This center specializes in detoxification, treatment for substance use disorders, and tailored support for individuals facing both substance use challenges and serious mental health issues in adults, as well as emotional difficulties in children. Offering intensive outpatient, outpatient, and day treatment programs, the facility prioritizes counseling for substance use disorders. Distinctive programs are available for adolescents, adult men, and adult women. Catering to individuals of all ages and genders, Alternative Paths Inc is dedicated to providing high-quality care through a customized treatment approach.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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