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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Altium Health LLC
West Jordan, UT

Altium Health LLC, located in West Jordan, UT, stands out as a premier rehabilitation center dedicated to detox and addiction treatment for both adults and young adults. Emphasizing varied options such as intensive outpatient, outpatient, and day treatment programs, the center tailors its services for adult men, adult women, and those impacted by intimate partner or domestic violence. Their therapeutic strategies encompass 12-step programs, anger management, and concise intervention methods to meet the unique needs of each client. With a strong dedication to delivering exceptional care, this center provides a nurturing atmosphere for individuals pursuing thorough and individualized recovery from addiction.

Altruism Counseling Services

Altruism Counseling Services, located in Lexington, KY, delivers thorough substance abuse care. This includes specialized treatment for those facing both addiction and significant mental health challenges, whether in adults or children with serious emotional difficulties. Their services encompass intensive outpatient, standard outpatient, and regular outpatient therapy options. They employ proven methods such as 12-step facilitation, anger management, and brief intervention techniques. Altruism Counseling Services also offers targeted programs for active military personnel, adult men, and adult women, demonstrating a commitment to serving a wide spectrum of clients. The facility is dedicated to providing excellent care that is customized for each person's specific requirements, welcoming adults and young adults of all genders.

Alvarado Parkway Institute

Alvarado Parkway Institute in La Mesa, CA, provides a full spectrum of recovery programs. These include medically supervised detoxification, treatment for addiction, and dedicated support for individuals facing both substance abuse challenges and severe mental health issues in adults, as well as significant emotional distress in young people. Operating with 24-hour inpatient care for detoxification and treatment, the center incorporates proven methods like 12-step facilitation, anger management techniques, and brief intervention strategies. Specific interventions are available for those who have endured sexual abuse or trauma, and for individuals with dual diagnoses of mental health and substance use disorders. Alvarado Parkway Institute serves adults and young adults across all gender identities, offering personalized and effective treatment.

Ambrosia of Medford LLC

Ambrosia of Medford LLC, located in Medford, NJ, provides a wide array of addiction recovery services tailored for both adults and young adults grappling with substance use issues alongside mental health challenges. The center features targeted programs specifically for young adults and utilizes various therapeutic methods such as 12-step support, anger management, and brief motivational interventions, ensuring personalized treatment plans that address unique circumstances. The facility encompasses residential detox, 24-hour residential care, and short-term residential options, creating a nurturing atmosphere for healing. Committed to delivering high-quality treatment, Ambrosia of Medford LLC adopts a gender-sensitive approach for males and females alike, aiming to assist individuals in achieving enduring sobriety and improved emotional health.

American Behavioral Clinics

Situated in Milwaukee, WI, American Behavioral Clinics delivers extensive outpatient rehabilitation options for those facing challenges related to substance abuse and concurrent mental health issues. The center features services such as detoxification, 12-step support, anger management, and brief intervention initiatives. Tailored treatment paths are available for active military members, teenagers, and adult males. Prioritizing high-quality care, the center also provides outpatient treatment with methadone/buprenorphine or naltrexone to meet individual requirements. Catering to adults, youth, and individuals of all genders, this facility is a reliable option for those in search of effective and customized addiction recovery programs.

American Behavioral Clinics

American Behavioral Clinics in Milwaukee, WI provides extensive outpatient care for detox, addiction, and co-occurring mental health issues for all ages. They have specific tracks for military personnel, teens, and adult men. Treatment methods incorporate 12-step support, anger management techniques, and brief intervention strategies. The clinic also offers outpatient medication management with methadone, buprenorphine, or naltrexone for both male and female patients. Dedicated to high-quality, individualized recovery plans, American Behavioral Clinics is a reliable option for those needing effective and supportive addiction recovery.

American Treatment Network

Nestled in Havertown, PA, the American Treatment Network delivers expert rehabilitation services. The center specializes in intensive outpatient programs, day treatment, and partial hospitalization for those struggling with substance use issues and co-occurring mental health disorders. Emphasizing 12-step support, anger management, and brief intervention techniques, this facility serves active duty military members, as well as adult men and women. Customized programs are designed for both adults and young adults, providing thorough care for a diverse group of individuals pursuing recovery. Count on the American Treatment Network for reliable, evidence-driven treatment in a nurturing atmosphere.

Amethyst Recover Center LLC
Port Saint Lucie, FL

Amethyst Recovery Center LLC, located in Port Saint Lucie, FL, provides a wide range of services for addiction rehabilitation. This center focuses on detoxification and treatment for substance use, specifically designed for adult individuals experiencing dual diagnoses. Amethyst Recovery Center LLC features both residential and short-term residential options, ensuring around-the-clock care in a nurturing setting. Their treatment methods incorporate 12-step programs, anger management techniques, and cognitive behavioral therapy, allowing for a well-rounded and tailored recovery experience. Dedicated to adults and young adults of all genders, this center emphasizes high-quality care and personalized assistance on each client's path to wellness.

Amity Foundation

The Amity Foundation in Tucson, AZ, provides extensive residential rehabilitation for adults dealing with substance abuse and associated mental health conditions, as well as children with significant emotional challenges. Their approach incorporates 12-step principles, anger management techniques, and cognitive behavioral therapy, offering personalized treatment for active military members, adult men, and women. The center features distinct programs for adults and young adults of all genders, fostering a welcoming and supportive setting for recovery. Emphasizing proven methods and a focus on overall well-being, Amity Foundation is dedicated to assisting individuals on their journey to addiction recovery.

American Treatment Network LLC

American Treatment Network LLC, located in Newark, DE, offers a wide range of services for individuals dealing with substance use issues and concurrent mental health conditions, catering to both adults and children. The center features intensive outpatient and outpatient options, which include treatments with methadone and buprenorphine. Various therapeutic approaches, such as 12-step support, anger management, and brief interventions, are employed to aid recovery. Tailored programs are available for active duty military personnel as well as adult men and women, ensuring comprehensive support for all clients. The center is dedicated to delivering high-quality care and creating personalized treatment plans to assist individuals in their recovery journey.

Amity Foundation
Los Angeles, CA

Situated in Los Angeles, CA, the Amity Foundation provides extended residential treatment for adult males facing substance use challenges within a nurturing setting. The center offers various housing solutions, including transitional living, halfway houses, and sober living environments. Its programs emphasize 12-step facilitation, anger management techniques, and brief intervention strategies, specifically designed for individuals who have dealt with trauma or those involved in the criminal justice system. Focused on the needs of adult men, including seniors and younger adults, the facility ensures exceptional care aimed at facilitating recovery. Should you or someone close to you need in-depth substance use treatment, the Amity Foundation may be an ideal option for achieving meaningful change.

American Indian Changing Spirits

American Indian Changing Spirits, situated in Long Beach, CA, delivers thorough addiction treatment and targeted support for those facing dual mental health diagnoses. This establishment features extended, brief, and round-the-clock live-in programs customized for adults and young adults. Emphasizing 12-step support, emotional regulation techniques, and short-term intervention strategies, the center serves male and female patients, including adult women and survivors of trauma. Renowned for its effective treatment and personalized recovery paths, this center is a reliable option for individuals pursuing freedom from dependency and emotional struggles.

American Treatment Network

Situated in Dover, DE, the American Treatment Network delivers an extensive range of substance abuse rehabilitation services. Emphasizing intensive outpatient care, as well as various outpatient alternatives including methadone, buprenorphine, or naltrexone treatments, this center is dedicated to providing personalized support for those in recovery. Utilizing evidence-based practices like cognitive behavioral therapy, anger management, and motivational incentives, the facility addresses diverse needs. Specific programs are designed for active military members, as well as adult males and females. Catering to both adults and young adults, this establishment strives to offer exceptional care and assistance for individuals overcoming addiction challenges.

Amazing Care Health Services LLC

Amazing Care Health Services LLC, situated in Gwynn Oak, MD, delivers extensive addiction recovery support. This center provides inpatient hospital care, intensive outpatient programs, and supervised residences for those overcoming substance dependency. Utilizing methods like 12-step encouragement, emotional regulation techniques, and short-term counseling, they serve adults and older adults facing dual mental health conditions. Dedicated programs are offered for younger individuals, ensuring customized support across different life stages. Both male and female clients receive personalized recovery strategies designed for sustained abstinence.

American Health Services LLC

American Health Services LLC in Palmdale, CA, provides outpatient services for adults and young adults struggling with substance use disorders. Their program includes medication-assisted treatment options like methadone, buprenorphine, or naltrexone, integrated with evidence-based therapies such as motivational interviewing, relapse prevention strategies, and individual counseling. The facility prioritizes a personalized approach to care, developing custom treatment plans for all clients, regardless of gender. For those in Palmdale looking for effective and individualized addiction recovery support, American Health Services LLC offers dedicated and specialized assistance.

American Psychiatric Group PA

American Psychiatric Group PA, located in Baltimore, MD, delivers thorough addiction recovery services for adults and older individuals. They offer detox, treatment for substance misuse, and targeted support for those with dual diagnoses of substance use disorders and significant mental health issues in adults, or severe emotional challenges in children. Their program emphasizes intensive outpatient and outpatient care, employing proven therapeutic methods like anger management, cognitive behavioral therapy, and motivational interviewing. Each client receives a customized recovery plan for individualized support. This center accommodates both men and women, fostering a nurturing atmosphere dedicated to high-quality rehabilitation.

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Encino, CA

Altus Rehab in Encino, CA, provides extensive addiction recovery solutions for adults and adolescents. The center excels in long-term residential care, inpatient detox, and round-the-clock support for individuals battling substance abuse. Altus Rehab employs a variety of therapeutic methods, such as 12-step program integration, anger management techniques, and concise therapeutic interventions. Catering to distinct needs, they offer tailored programs for adult men, adult women, and those with a history of trauma, ensuring personalized attention for everyone. Altus Rehab prioritizes a nurturing atmosphere through its separate treatment tracks for men and women. Discover exceptional support and customized recovery plans at Altus Rehab.

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Amazing Care Health Services LLC, located in Baltimore, MD, provides an extensive range of services for those dealing with substance use challenges, including transitional housing and sober living arrangements. The center is dedicated to addressing both substance use and concurrent severe mental health conditions, offering specialized inpatient and intensive outpatient programs for adults and seniors. Emphasizing methods such as 12-step support, anger management, and brief intervention strategies, the facility also accommodates adolescents and young adults. With a commitment to delivering exceptional care in a nurturing setting, individuals of all genders can access customized treatment plans designed to promote enduring recovery.

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Amazing Care Health Services LLC, located in Baltimore, MD, delivers a complete spectrum of recovery support for those overcoming substance use challenges. Their offerings include inpatient hospital care, intensive outpatient programs, and structured living arrangements, all customized to individual client requirements. Employing proven methods like 12-step guidance, emotional regulation training, and concise intervention strategies, the center promotes a well-rounded and individualized recovery path. With dedicated programs for younger individuals and comprehensive services for adults and older adults, regardless of gender, this center fosters an inclusive atmosphere for all on their journey toward wellness.

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Idaho Falls, ID

AmericaHealth in Idaho Falls, ID, delivers extensive substance abuse treatment designed for adults and young adults facing concurrent severe mental health challenges. The center provides diverse outpatient services, including intensive outpatient programs and day treatment, to craft individualized recovery plans. Dedicated tracks are available for active-duty military, men, and women, offering focused assistance. Employing methodologies like 12-step encouragement and anger management, the facility prioritizes customized care to foster enduring sobriety. AmericaHealth is committed to offering effective treatment within a nurturing setting for those aiming to conquer addiction and enhance their mental well-being.

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American Health Services LLC, located in Venice, CA, provides outpatient detox and substance use treatment for both adults and young adults. This center is dedicated to personalized care, utilizing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Emphasizing an individualized approach, their programs are designed for clients of all genders. American Health Services LLC offers outpatient treatments involving methadone, buprenorphine, or naltrexone to assist individuals in recovery. With a commitment to high-quality care and a variety of therapeutic options, this facility stands out as an excellent choice for those seeking customized addiction treatment in the Venice region.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)