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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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High Country Behavioral Health

High Country Behavioral Health, situated in Idaho Falls, ID, delivers extensive care for adults and older individuals facing challenges with addiction and concurrent mental health issues. This center features intensive outpatient programs, outpatient detox services, and regular outpatient counseling, all grounded in proven therapeutic methods including cognitive behavioral therapy, anger control techniques, and motivational interviewing. They also have dedicated programs for active service members, teenagers, and adult men. Prioritizing tailored treatment plans, High Country Behavioral Health cultivates a nurturing atmosphere for all clients, male and female, on their journey toward sustained recovery and enhanced emotional health.

High Country Community Health

High Country Community Health, located in Boone, NC, delivers dedicated substance use disorder support via outpatient programs designed for your unique requirements. Employing proven methods including brief intervention, cognitive behavioral therapy, and contingency management, this establishment furnishes complete care for individuals of all ages. Prioritizing customized recovery strategies, High Country Community Health guarantees a nurturing and successful path to sobriety for all clients. Their dedication to excellent service and personalized plans establishes them as a crucial asset for anyone seeking help with addiction in Boone.

High Country Community Health

High Country Community Health in Boone, NC, provides a full spectrum of outpatient substance use disorder services, incorporating medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach integrates scientifically validated methods such as cognitive behavioral therapy and contingency management/incentive-based strategies to foster recovery. The center is committed to personalized care, serving adults and young people alike with customized support. High Country Community Health ensures an affirming space for everyone, regardless of gender identity, to embark on their healing process. Discover dedicated, person-centered treatment aimed at promoting enduring recovery.

High Focus Treatment Centers

High Focus Treatment Centers, located in Cherry Hill, NJ, delivers tailored programs for adults and adolescents struggling with substance abuse and co-occurring mental health conditions. They offer a range of services including intensive outpatient, outpatient, and day treatment. Their therapeutic strategies incorporate anger management, cognitive behavioral therapy, and motivational interviewing, all adapted to each person's specific journey. The center features specialized care for young people, the LGBTQ+ community, and individuals facing dual diagnoses, promoting holistic healing. High Focus Treatment Centers is committed to providing effective, evidence-based support for sustained recovery to all clients.

High Country Behavioral Health

High Country Behavioral Health, located in Afton, WY, offers a variety of targeted therapies for individuals dealing with substance abuse as well as dual mental health issues. This center features intensive outpatient services, general outpatient support, and options for methadone, buprenorphine, or naltrexone treatment. Employing techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, the center serves both adults and seniors, with dedicated programs for active duty personnel, teenagers, and adult males. By emphasizing personalized care, High Country Behavioral Health provides effective treatment solutions for all clients, regardless of gender, who are on their journey to recovery.

High Country Community Health

High Country Community Health, located in Newland, NC, provides a wide range of substance use treatment options through specialized outpatient programs designed for adults, children, and teenagers. The facility emphasizes personalized care, employing proven methods such as cognitive behavioral therapy and contingency management. By concentrating on short-term interventions, High Country Community Health offers outpatient treatment options that include methadone, buprenorphine, or naltrexone, in addition to standard outpatient services. The center is committed to delivering high-quality care to all clients, regardless of gender, in a supportive and inviting atmosphere.

Hickory Treatment Center at Corydon

Hickory Treatment Center at Corydon, situated in Corydon, IN, provides a wide range of detox and substance abuse services tailored for adult men. The center is adept in handling co-occurring substance misuse along with significant emotional issues in children. They offer residential detox services, 24-hour care, and short-term residential options. Employing methods such as 12-step guidance, anger management techniques, and brief intervention strategies, the facility serves active military members and individuals who have faced domestic violence. Emphasizing top-quality care for adults, seniors, and young adults, this center specializes in helping male clients on their path to recovery from addiction and mental health struggles.

Hickory Treatment Center at Rockville

Hickory Treatment Center at Rockville, situated in Rockville, IN, offers a wide range of rehabilitation services specifically for adult males facing challenges with substance use disorders and concurrent serious mental health issues. The facility features residential detox programs, around-the-clock care, and short-term residential options, employing evidence-based methods such as 12-step facilitation and cognitive behavioral therapy. With a unique focus on anger management, this center is dedicated to providing tailored treatment for adult men. Hickory Treatment Center at Rockville prioritizes high-quality care and assistance for adult, senior, and young adult male clients seeking help with addiction and mental health needs.

High Focus Centers
Somerville, NJ

High Focus Centers in Somerville, NJ, delivers a full spectrum of care for individuals of all ages facing substance use and dual diagnoses. Their offerings include intensive outpatient, standard outpatient, and partial hospitalization options, integrating therapeutic strategies like 12-step integration, anger de-escalation, and brief counseling techniques. The facility features distinct tracks for adult men, adult women, and those managing concurrent mental health and addiction challenges, demonstrating a commitment to tailored support. High Focus Centers is dedicated to providing high-quality, personalized treatment plans for adults, children, and adolescents, fostering lasting recovery and improved health.

Hickory Treatment Center
Indianapolis, IN

Situated in Indianapolis, IN, Hickory Treatment Center delivers a wide range of rehabilitation services specifically designed for adult men grappling with substance abuse and concurrent mental health challenges. The center features targeted programs for active duty military members, survivors of intimate partner violence, and individuals seeking assistance with anger management. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, the facility provides hospital inpatient and residential treatment alternatives. Concentrating on adults and seniors, Hickory Treatment Center is dedicated exclusively to male clients, guaranteeing customized and impactful support that meets the distinct needs of every individual.

High Country Behavioral Health

High Country Behavioral Health, located in Kemmerer, WY, provides dedicated rehabilitation services for individuals facing substance use issues and related mental health challenges. The center features various programs, including intensive outpatient options, standard outpatient treatment, and medication-assisted therapies with methadone/buprenorphine or naltrexone. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, this facility supports active duty military personnel, teenagers, and adult males. Catering to adults and seniors of any gender, High Country Behavioral Health is committed to delivering personalized care and assistance to those striving to conquer addiction and enhance their mental health.

High Country Behavioral Health

High Country Behavioral Health, situated in Pinedale, WY, delivers targeted care for adults managing co-occurring mental health conditions and substance use disorders. Their services include comprehensive outpatient programs and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing approaches like anger management, CBT, and motivational interviewing, the center supports active duty military, young adults, and adult males. High Country Behavioral Health is dedicated to providing effective, personalized treatment for adults and seniors across all genders.

High Country Behavioral Health

High Country Behavioral Health in Rawlins, WY, specializes in dual diagnosis treatment for adults with significant mental health challenges and children experiencing severe emotional distress. They offer comprehensive outpatient and intensive outpatient services, incorporating medication-assisted treatment like methadone, buprenorphine, or naltrexone. Treatment plans are personalized, utilizing approaches such as anger management, cognitive behavioral therapy, and motivational interviewing. Distinct programs are provided for active duty military personnel, teenagers, and adult males. High Country Behavioral Health supports adults and seniors across all genders, delivering effective care and assistance for individuals pursuing complete recovery.

High Focus Centers
Philadelphia, PA

High Focus Centers in Philadelphia, PA, delivers extensive addiction treatment solutions for adults and young adults facing co-occurring serious mental health conditions. Their offerings include intensive outpatient, outpatient day treatment, and partial hospitalization programs, employing methods like 12-step facilitation, anger management, and brief intervention. Dedicated services are available for active military, adult men, and adult women. Emphasizing personalized care, the center customizes treatment strategies for each individual's specific requirements. High Focus Centers is committed to delivering high-quality care in a nurturing setting for those pursuing sobriety.

High Country Behavioral Health

High Country Behavioral Health in Thermopolis, WY, delivers targeted care for individuals facing substance use challenges and co-occurring mental health conditions, catering to both young people and adults. Their offerings include robust intensive outpatient and standard outpatient services, notably incorporating medication-assisted treatment with methadone or buprenorphine. The facility emphasizes evidence-based approaches such as anger management, cognitive behavioral therapy, and motivational interviewing, ensuring personalized treatment plans. Specialized interventions are available for active-duty military personnel, teenagers, and adult males, further enriching their support system. High Country Behavioral Health extends its comprehensive recovery and mental wellness services to adults and seniors across all gender identities, fostering a supportive atmosphere for healing.

High Country Community Health

High Country Community Health in Morganton, NC, provides comprehensive outpatient care for adults and young individuals grappling with substance use disorders. Their services encompass medication-assisted treatment options like methadone, buprenorphine, or naltrexone, alongside traditional outpatient services. A strong emphasis is placed on evidence-based practices such as brief intervention, cognitive behavioral therapy, and motivational strategies including contingency management. The center is dedicated to a personalized approach, ensuring that treatment plans are specifically designed for each client, accommodating both male and female individuals. High Country Community Health fosters a nurturing setting, committed to delivering effective and customized recovery pathways.

High Country Behavioral Health

High Country Behavioral Health, situated in Douglas, WY, provides an extensive range of services for individuals dealing with substance use disorders and concurrent severe mental health challenges in adults, alongside addressing significant emotional issues in children. The facility emphasizes both intensive outpatient and outpatient treatment options, incorporating medications like methadone/buprenorphine or naltrexone. Utilizing various evidence-based methods such as anger management, cognitive behavioral therapy, and motivational interviewing, High Country Behavioral Health supports active duty military members, adolescents, and adult men, ensuring comprehensive and customized care for adults and seniors of all backgrounds.

High Country Behavioral Health

High Country Behavioral Health in Lyman, WY, is dedicated to providing tailored care for adults facing substance use disorders, particularly those also dealing with significant mental health conditions or emotional challenges in young people. The center's offerings include robust intensive outpatient and outpatient programs, featuring medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods such as anger management, cognitive behavioral therapy, and motivational interviewing, the facility addresses the specific requirements of active duty military members, teenagers, and adult men. High Country Behavioral Health also extends its comprehensive rehabilitation and support services to adults and seniors across all gender identities, ensuring everyone receives high-quality assistance.

High Country Behavioral Health

High Country Behavioral Health in Lusk, WY, provides outpatient services for individuals struggling with substance use disorders. Their programs address co-occurring mental health conditions in adults and emotional challenges in youth. The center has dedicated offerings for active military personnel, teenagers, and adult males. Treatment modalities employed include anger management techniques, cognitive behavioral therapy, and motivational interviewing. Available medication-assisted treatment options include methadone, buprenorphine, and naltrexone for adult and senior patients of all genders. High Country Behavioral Health is committed to delivering effective and individualized care within a nurturing setting.

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High Plains Mental Health Center in Norton, KS, offers specialized outpatient treatment for substance use and co-occurring serious mental health conditions in adults and serious emotional disturbances in children. The center provides cognitive behavioral therapy, motivational interviewing, and substance use disorder counseling to address individual needs. With a focus on tailored care, this facility offers outpatient methadone/buprenorphine or naltrexone treatment along with regular outpatient services. Serving adults and seniors of all genders, the center ensures quality care through its unique individual approach programs. If you are seeking personalized and effective addiction treatment, High Plains Mental Health Center is dedicated to supporting your journey to recovery.

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High Plains Mental Health Center located in Phillipsburg, KS, provides targeted outpatient services for individuals dealing with substance use issues and co-occurring mental health conditions, catering to both adults and youth. The programs incorporate techniques like cognitive behavioral therapy, motivational interviewing, and specific counseling for substance use disorders. Emphasizing personalized treatment, this center offers options such as outpatient methadone/buprenorphine or naltrexone therapy, alongside conventional outpatient services. Accommodating adults and seniors of various backgrounds, High Plains Mental Health Center is committed to crafting a unique treatment plan for each person. For those in pursuit of effective addiction recovery with a focus on individualized support, this facility is devoted to delivering compassionate and impactful care.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)