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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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High Watch Recovery Center

High Watch Recovery Center, located in Kent, CT, provides an array of extensive services aimed at treating addiction for both adults and young adults. The center's offerings encompass detoxification, substance abuse treatment, transitional housing, and sober living arrangements. It focuses on various recovery approaches such as intensive outpatient, long-term residential, and standard outpatient programs. High Watch Recovery Center is adept at delivering 12-step facilitation, anger management strategies, and short-term interventions. Programs are customized for men and women, including those who have faced trauma, ensuring the center maintains a nurturing and organized setting for individuals on their path to recovery from addiction.

Highland Ridge Hospital

Highland Ridge Hospital, located in Midvale, UT, delivers complete addiction recovery programs for individuals of all ages. The facility offers inpatient hospital detox, care for substance dependence, and support for co-occurring severe mental health issues. Treatment methodologies employed include motivational interviewing, dialectical behavior therapy, and aftercare planning. Highland Ridge Hospital serves distinct groups including veterans, teens, and adult women. With programs adaptable for both sexes, the center guarantees personalized support for everyone. Clients will find superior treatment and scientifically validated therapeutic methods here, positioning it as a leading option for those pursuing successful recovery.

Highlife Recovery
Grove City, OH

Highlife Recovery, located in Grove City, OH, provides an all-encompassing approach to substance abuse treatment, along with specialized support for individuals experiencing co-occurring mental health issues. Their outpatient services, which include intensive care options, are designed for both adults and young adults, regardless of gender. What sets Highlife Recovery apart are its customized strategies, such as 12-step support, anger management, and targeted brief interventions. The center also offers distinctive programs for individuals dealing with simultaneous pain and substance use disorders, ensuring that each person receives personalized, effective care. Committed to excellence and individualized support, this center serves as a guiding light for those on the path to recovery.

Hill Alcohol and Drug Treatment

Hill Alcohol and Drug Treatment, situated in Temecula, California, delivers thorough programs for addiction recovery. This center offers detox and substance abuse treatment through different levels of care, such as intensive outpatient, outpatient, and day treatment. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, the facility supports adolescents and adult men and women. Hill Alcohol and Drug Treatment provides tailored treatment considering gender and age, accommodating both adults and young people. Clients can anticipate top-tier, specialized care to aid in their path to lasting sobriety.

His House Treatment Center

His House Treatment Center, situated in Upland, CA, provides exceptional long-term residential and detoxification services specifically designed for men battling substance use disorders. Their approach integrates 12-step facilitation, anger management techniques, and brief intervention strategies to offer customized care plans for adults, seniors, and young adults. This center prioritizes a personalized treatment experience, ensuring every individual's needs are met. Renowned for its high standards and programs centered on men's recovery, His House Treatment Center is a premier option for individuals pursuing thorough and impactful addiction treatment.

Hinds Behavioral Health Services

Hinds Behavioral Health Services in Jackson, MS, delivers tailored treatment for individuals struggling with addiction and mental health challenges, catering to both young people and adults. Their offerings include comprehensive outpatient and intensive outpatient options, featuring medication-assisted treatment with methadone or buprenorphine. Emphasizing techniques such as anger management, brief intervention strategies, and cognitive behavioral therapy, the center customizes care plans for each person. They have dedicated programs for teenagers, adult men, and adult women. Serving a diverse population including seniors, Hinds Behavioral Health Services is committed to providing effective, compassionate support throughout the recovery process.

His House Palm Recovery

Situated in Upland, California, His House Palm Recovery provides targeted addiction treatment services specifically designed for adult and senior men. This center features long-term residential programs, detoxification services, and continuous support from staff. The treatment methodology incorporates 12-step facilitation, anger management strategies, and cognitive behavioral therapy to effectively tackle substance use disorders. Emphasizing personalized treatment plans, this facility adapts its services to cater to the distinct needs of each individual. His House Palm Recovery is distinguished by its dedication to high-quality care and a tailored approach to rehabilitation, making it a superb option for men in need of thorough and successful addiction treatment.

High Point OTP New Bedford

High Point OTP New Bedford, located in New Bedford, MA, offers a wide range of treatment options for adults and children dealing with substance use disorders and significant mental health challenges. The facility delivers intensive outpatient programs, outpatient services, and targeted treatment with methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, High Point OTP New Bedford is designed for individuals who have faced trauma, intimate partner violence, domestic abuse, and sexual assault. Services are available to all genders, ensuring that care is customized to meet the unique needs of each client. The center is committed to delivering high-quality, research-supported treatment to assist clients in their recovery journey.

Highland Health Rivers

Highland Health Rivers in Rome, GA, delivers extensive recovery programs for adults and young adults. The center is dedicated to addressing addiction and co-occurring mental health conditions, offering robust outpatient services and supportive living arrangements. Their therapeutic methods include established principles like 12-step principles, emotional regulation skills, and concise counseling strategies. Tailored to assist adult men, adult women, and survivors of domestic abuse, Highland Health Rivers prioritizes personalized care. From partial hospitalization to outpatient care, individuals receive effective support within a nurturing setting aimed at fostering sustained well-being.

Highland Rivers Behavioral Health

Highland Rivers Behavioral Health, located in Rome, GA, presents a wide array of services aimed at helping individuals recover from substance abuse and associated mental health issues. The center features residential detox programs, around-the-clock residential support, and short-term residential options designed for both adults and young adults. By employing proven techniques such as cognitive behavioral therapy and the Matrix Model, the facility effectively addresses the needs of clients experiencing dual challenges. Highland Rivers Behavioral Health is particularly noted for its dedicated programs for individuals dealing with both mental health and substance use disorders, providing custom care plans for each client. With an emphasis on effective and personalized treatment, this center serves as a guiding light for those seeking recovery.

Highlands Community Services

Highlands Community Services, located in Abingdon, VA, delivers comprehensive care for individuals grappling with substance use challenges and co-occurring mental health conditions, serving both young and adult populations. Their treatment modalities encompass intensive outpatient, standard outpatient, and medication-assisted options, employing evidence-based strategies like anger management, cognitive behavioral therapy, and brief intervention. The center features distinct programs tailored for adolescents, adult men, and women, addressing specific demographic needs. Furthermore, Highlands Community Services extends its services to adults and seniors across all genders, prioritizing high-quality, individualized recovery plans.

Hilltop Recovery Services
Clearlake Oaks, CA

Situated in Clearlake Oaks, CA, Hilltop Recovery Services specializes in treating substance use disorders in a tranquil residential atmosphere. The center offers a range of treatment options, including long-term and short-term residential programs, designed for both adults and young adults. Emphasizing 12-step facilitation, anger management, and brief intervention methods, it serves clients of all genders. The facility also features distinctive programs for adult men, adult women, and individuals who have encountered trauma. Hilltop Recovery Services is committed to providing exceptional care in a nurturing environment, assisting individuals as they embark on their recovery journey.

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High Plains Mental Health Center, located in Osborne, KS, provides focused outpatient services for individuals grappling with substance use and concurrent disorders, catering to both adults and children. Through the implementation of cognitive behavioral therapy, motivational interviewing, and specialized counseling for substance use disorders, the center ensures that care is tailored to meet the unique needs of each participant. The facility features programs specifically created for adults and seniors, regardless of gender, distinguishing itself through its customized treatment strategies. Services encompass outpatient treatments using methadone, buprenorphine, or naltrexone, alongside consistent outpatient therapy sessions. High Plains Mental Health Center is committed to offering exceptional, individualized care that empowers individuals on their journey toward recovery.

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High Plains Mental Health Center, located in Colby, KS, provides targeted outpatient services for individuals dealing with substance use disorders and concurrent mental health challenges, catering to both adults and children. The center emphasizes techniques such as cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders, ensuring that each client's treatment plan is personalized. Focused on outpatient options including methadone/buprenorphine and naltrexone therapies, this facility accommodates adults and seniors of all genders. High Plains Mental Health Center is distinguished by its holistic strategy to tackle issues related to addiction and mental well-being, delivering exceptional care and support to each person as they embark on their recovery journey.

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High Plains Mental Health Center in Goodland, KS, delivers targeted outpatient services for individuals grappling with addiction and concurrent severe mental health concerns, as well as for children experiencing significant emotional distress. Their approach centers on personalized interventions, employing strategies such as cognitive behavioral therapy, motivational interviewing, and dedicated substance use disorder counseling. By crafting programs that are uniquely suited to each client, High Plains Mental Health Center prioritizes a personalized journey toward recovery. The center caters to adults and seniors across the gender spectrum, also providing outpatient medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Patients can anticipate receiving caring and successful support from this well-regarded treatment facility.

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High Plains Mental Health Center, located in Hays, KS, specializes in outpatient programs for individuals of all ages struggling with addiction and accompanying mental health conditions. Their therapeutic offerings utilize proven methods such as 12-step support, short-term counseling, and cognitive behavioral techniques. Prioritizing a personalized approach, the center crafts treatment strategies to address the distinct requirements of every patient. Serving a diverse clientele including adults and older adults of any gender, High Plains Mental Health Center delivers comprehensive care through outpatient options like methadone, buprenorphine, or naltrexone, alongside standard outpatient services.

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High Point Brockton, located in Brockton, MA, provides a wide array of services for those facing addiction challenges. The facility includes detox services, treatment for substance use disorders, and targeted support for individuals dealing with both substance use and significant mental health issues. High Point Brockton offers a variety of programs, including intensive outpatient options, regular outpatient care, and outpatient detox, making it suitable for adults and young adults of all genders. The center adheres to evidence-based practices, such as 12-step programs, anger management, and brief interventions, to deliver effective and tailored treatment. Additionally, specialized programs for pregnant and postpartum women demonstrate the center's dedication to meeting specific patient needs. Discover compassionate and high-quality care at High Point Brockton.

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High Point Brockton, located in Brockton, MA, offers a wide variety of treatment programs for substance use aimed at adults and young adults. The facility specializes in addressing the needs of those with dual diagnoses, combining substance use disorders with serious mental health issues or emotional challenges. Treatment options include intensive outpatient services, standard outpatient care, and methadone/buprenorphine or naltrexone therapies. High Point Brockton emphasizes anger management strategies, brief intervention techniques, and cognitive behavioral therapy, creating customized programs for adult men, women, and individuals affected by intimate partner or domestic violence. With a gender-specific focus, they provide tailored care to ensure high-quality rehabilitation services for all clients.

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High Point OTP Plymouth, located in Plymouth, MA, specializes in outpatient care for substance use disorders. The center offers a variety of treatments, including outpatient methadone/buprenorphine and naltrexone therapies, alongside standard outpatient services. A diverse selection of therapeutic methods is available, such as cognitive behavioral therapy, brief interventions, and anger management. They also have targeted programs for active duty military members, teenagers, and adult males. Services are designed for adults and young adults across all gender identities. With an emphasis on personalized care and effective treatment plans, this center stands out as an excellent option for those in need of thorough addiction recovery support in a nurturing setting.

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High Point Partial Care, located in Flemington, NJ, provides tailored treatment for adults and children dealing with substance use and concurrent disorders. The center offers various programs, including intensive outpatient, outpatient, and partial hospitalization, utilizing methodologies such as 12-step facilitation, anger management, and brief intervention techniques. Placing an emphasis on trauma-informed care, High Point Partial Care serves adult men and women as well as individuals who have faced traumatic experiences. The facility supports clients of all genders, delivering thorough and personalized care to assist them in their recovery process.

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Hildas Place Behavioral Health, situated in Westminster, MD, delivers extensive treatment for substance use and specialized support for those grappling with severe mental health issues or emotional challenges. The center emphasizes both intensive outpatient and outpatient services, offering customized options such as anger management, brief interventions, and motivational rewards. They provide distinctive programs for active duty military members, as well as for adult men and women, accommodating individuals across various age ranges, from children to the elderly. By employing a gender-specific strategy for both men and women, this facility is dedicated to providing exceptional care that aids individuals in their recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)